Physical FitnessPLBT-ATHNCT07398248
Effects of Powerlifting-Based Training in Athletes
A study testing Powerlifting-Based Training, Usual Basketball Training and Blood Sampling and Laboratory Analysis in people with Physical Fitness and Hormonal Response, run by Ramazan Erdoğan at 2 sites in Turkey (Türkiye).
Trial summary
This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. Read more about this study
- Who is it for?
- Ages 18 to 24 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Physical Fitness, Hormonal Response, Metabolic Parameters
- What is being tested?
- Powerlifting-Based Training, Usual Basketball Training and Blood Sampling and Laboratory Analysis
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 10 Jan 2025to 15 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Male basketball players aged 18 to 24 years
- At least two years of regular sports experience
- Actively participating in basketball training and competition
- Voluntary participation with written informed consent
Who cannot join
- History of musculoskeletal injury or surgery within the last six months
- Presence of chronic disease or metabolic disorder
- Use of performance-enhancing drugs or hormonal supplements
- Participation in another structured training program during the study period
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Munzur University
Bitlis, Tunceli, 62000
Faculty of Sport Sciences
Tunceli, Center, 62000
About this study
Official title: The Effects of Powerlifting-Based Training on Hormonal, Metabolic, and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial
This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.
Read the detailed description
This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines.
The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.
- Conditions
- Physical Fitness, Hormonal Response, Metabolic Parameters
- Being tested
- Powerlifting-Based Training, Usual Basketball Training, Blood Sampling and Laboratory Analysis
- Keywords
- Powerlifting, Strength Training, Basketball
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Powerlifting-Based TrainingOther
Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision.
Usual Basketball TrainingOther
Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises.
Blood Sampling and Laboratory AnalysisOther
Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.
| Study group | Role | What they receive |
|---|---|---|
| Powerlifting-Based Training Group | Experimental | Participants performed a structured powerlifting-based training program in addition to their regular basketball training. The intervention was conducted three days per week for six weeks. Each session lasted approximately 60 minutes and included a standardized warm-up, a powerlifting-focused main training phase, and a cool-down period.
The training program emphasized the squat, bench press, and deadlift exercises performed with progressive intensity. Accessory exercises targeting lower-body strength, upper-body musculature, and core stability were included. High-intensity bodyweight exercises were also performed to enhance anaerobic capacity and neuromuscular performance. All training sessions were supervised by qualified staff. Receives: Other: Powerlifting-Based Training; Other: Blood Sampling and Laboratory Analysis |
| Control Group | Other | Participants continued their usual basketball training routines throughout the study period without any additional strength or powerlifting-based exercises. Receives: Other: Usual Basketball Training; Other: Blood Sampling and Laboratory Analysis |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)
Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)
Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)
Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)
Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)
Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)
Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Secondary outcomes (6)
Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)
Mean difference between baseline and post-intervention fasting serum insulin concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Mean difference between baseline and post-intervention fasting blood glucose concentrations, measured from venous blood samples using an automated biochemical analyzer.
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Mean difference between baseline and post-intervention total cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Mean difference between baseline and post-intervention low-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Measured: Baseline and post-intervention (8 weeks)
Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Mean difference between baseline and post-intervention high-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Measured: Baseline and post-intervention (8 weeks)
Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Mean difference between baseline and post-intervention triglyceride concentrations, measured from venous blood samples using an automated biochemical analyzer.
Measured: Baseline and post-intervention (8 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Feb 2026
- Study start10 Jan 2025
- Primary completion15 Jun 2025
- Study completion15 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Physical FitnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ramazan Erdoğan
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Ramazan Erdoğan, Munzur University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07398248
- Sponsor's protocol ID
- E-31679287-663.05-523405
- Other IDs
- E-31679287-663.05-523405
- Acronym
- PLBT-ATH
- Status last verified
- Jan 2026
- First submitted
- 29 Dec 2025
- Last updated
- 9 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to ethical restrictions, participant confidentiality concerns, and the absence of participant consent for data sharing beyond the scope of this study.
Publications
Tizar E, Erdogan R. Short-term effects of powerlifting-based training on hormonal, metabolic, and lipid profile markers in male basketball players: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2026 Jul 1. doi: 10.1186/s13102-026-01832-4. Online ahead of print.
PubMed 42387653
Study at a glance
From the registry record, last updated by the sponsor on 9 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Powerlifting-Based Training on Hormonal, Metabolic, and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07398248
- Acronym / sponsor ID
- PLBT-ATH / E-31679287-663.05-523405
- Conditions
- Physical Fitness, Hormonal Response, Metabolic Parameters
- Keywords
- Powerlifting, Strength Training, Basketball
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Ramazan ErdoğanUniversity, hospital or other
- Study start
- 10 Jan 2025 (actual)
- Primary completion
- 15 Jun 2025 (actual)
- Study completion
- 15 Oct 2025 (actual)
- First posted
- 9 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.
Detailed description
This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines.
The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Powerlifting-Based Training Group | Experimental | Other: Powerlifting-Based Training, Other: Blood Sampling and Laboratory AnalysisParticipants performed a structured powerlifting-based training program in addition to their regular basketball training. The intervention was conducted three days per week for six weeks. Each session lasted approximately 60 minutes and included a standardized warm-up, a powerlifting-focused main training phase, and a cool-down period. The training program emphasized the squat, bench press, and deadlift exercises performed with progressive intensity. Accessory exercises targeting lower-body strength, upper-body musculature, and core stability were included. High-intensity bodyweight exercises were also performed to enhance anaerobic capacity and neuromuscular performance. All training sessions were supervised by qualified staff. |
| Control Group | Other | Other: Usual Basketball Training, Other: Blood Sampling and Laboratory AnalysisParticipants continued their usual basketball training routines throughout the study period without any additional strength or powerlifting-based exercises. |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Male basketball players aged 18 to 24 years
- At least two years of regular sports experience
- Actively participating in basketball training and competition
- Voluntary participation with written informed consent
Key exclusion criteria (4 listed)
- History of musculoskeletal injury or surgery within the last six months
- Presence of chronic disease or metabolic disorder
- Use of performance-enhancing drugs or hormonal supplements
- Participation in another structured training program during the study period
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Powerlifting-Based TrainingParticipants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision. | Other | Powerlifting-Based Training Group |
| Usual Basketball TrainingParticipants continued their usual basketball training routines without any additional strength or powerlifting-based exercises. | Other | Control Group |
| Blood Sampling and Laboratory AnalysisVenous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer. | Other | Control Group, Powerlifting-Based Training Group |
Primary outcome
Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
6 secondary outcomes
Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)
Time frame: Baseline and post-intervention (8 weeks)
Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL)
Time frame: Baseline and post-intervention (8 weeks)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Feb 2026.
- Derived from this study: PubMed 42387653Tizar E, Erdogan R. Short-term effects of powerlifting-based training on hormonal, metabolic, and lipid profile markers in male basketball players: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2026 Jul 1. doi: 10.1186/s13102-026-01832-4. Online ahead of print.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to ethical restrictions, participant confidentiality concerns, and the absence of participant consent for data sharing beyond the scope of this study.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Powerlifting-Based Training, Usual Basketball Training and Blood Sampling and Laboratory Analysis in people with Physical Fitness and Hormonal Response, run by Ramazan Erdoğan at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL) (time frame: Baseline and post-intervention (8 weeks)). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07398248, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Feb 2026.