VATSNCT07395661

Comparison Of Analgesic Methods İn Video-Assisted Thoracoscopic Surgery

A study testing Ultrasound guided serratus anterior plane block and Ultrasound guided serratus posterior superior intercostal plane block in people with VATS and Pain Management, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane… Read more about this study

Who is it for?: Ages 18 to 65 yearsHealthy volunteers can take part
Conditions the study is for: VATS, Pain Management, Plane Blocks
What is being tested?: Ultrasound guided serratus anterior plane block and Ultrasound guided serratus posterior superior intercostal plane block
Type of treatment: Surgery or procedure
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 60 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 13 Jan 2025to 13 Oct 2025
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 65 years
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent

Who cannot join

History of allergy or toxicity to local anesthetic agents
Known or suspected coagulopathy
Infection at the site of block injection
Advanced organ failure
Diagnosed mental retardation
Pregnancy

Show all 11Show fewer

Pediatric patients
History of thoracotomy
Requirement for postoperative intubation
Emergency surgery
Refusal to participate in the study

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

University of Health Siences Gazi Yasargil Training and Research Hospital
Diyarbakır, Kayapınar, 21100

Other trials in Turkey (Türkiye)

About this study

Official title: Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery

Patients with ASA grades I-III, aged 18-65, will be included in the study. Standard general anesthesia will be administered to the patients. Postoperative analgesia evaluation will be conducted using VAS and NRS scores at specific time points after surgery Additional analgesic requirements and patient satisfaction will be recorded.

Conditions: VATS, Pain Management, Plane Blocks
Being tested: Ultrasound guided serratus anterior plane block, Ultrasound guided serratus posterior superior intercostal plane block
Keywords: VATS, Pain Management, Plane Blocks, SPSIPB, SAPB
Medical subject headings: Agnosia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Ultrasound guided serratus anterior plane blockProcedure or surgery
Also called serratus anterior plane block
Ultrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral)
Ultrasound guided serratus posterior superior intercostal plane blockProcedure or surgery
Also called Serratus posterior superior intercostal plane block
Ultrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral)

Study groups in NCT07395661
Study group	Role	What they receive
SERRATUS ANTERİOR PLANE BLOCK	Experimental	Participants received an ultrasound-guieded serratus anterior plane block (SAPB) Receives: Procedure: Ultrasound guided serratus anterior plane block
SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK	Experimental	Participants received an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) Receives: Procedure: Ultrasound guided serratus posterior superior intercostal plane block

What is being measured

The primary outcome is the main question the study is designed to answer.

Postoperative pain intensity
Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

Secondary outcomes (5)

Postoperative pain intensity assessed by Numeric Rating Scale (NRS)
Postoperative pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst pain imaginable)
Measured: 30 minutes, 1, 4, 8, 12, 24 hours after surgery
Total 24-hour tramadol consumption
Total amount of rescue tramadol administered within the first 24 postoperative hours, recorded in milligrams
Measured: 24 hours after surgery
Rescue analgesia requirement
Proportion of patients requiring rescue analgesia (intravenous tramadol) at each postoperative assessment time point
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Adverse events
Incidence of local anesthetic systemic toxicity, pneumothorax, hypotension, nausea/vomiting, and block-related complications
Measured: Within 24 hours after surgery
Dynamic (movement-associated) postoperative pain intensity
Postoperative pain intensity during movement/coughing was assessed using the Visual Analog Scale (VAS), distinct from the primary outcome which assessed pain at rest (static VAS)
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

13 Jan 202513 Oct 2025

First posted9 Feb 2026
Study start13 Jan 2025
Primary completion11 Jul 2025
Study completion13 Oct 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for VATSStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Triple blind
Who is masked: Participant, Care provider, Outcomes assessor
Enrolment: 60 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07395661
Sponsor's protocol ID: 225
Status last verified: Jan 2026
First submitted: 24 Jan 2026
Last updated: 12 Aug 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All VATS trials

Study at a glance

From the registry record, last updated by the sponsor on 12 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery
ClinicalTrials.gov ID: NCT07395661
Acronym / sponsor ID: 225
Conditions: VATS, Pain Management, Plane Blocks
Keywords: VATS, Pain Management, Plane Blocks, SPSIPB, SAPB
Study type: Interventional
Recruitment status: Completed
Enrolment: 60 participants (actual)
Lead sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalUniversity, hospital or other
Study start: 13 Jan 2025 (actual)
Primary completion: 11 Jul 2025 (actual)
Study completion: 13 Oct 2025 (actual)
First posted: 9 Feb 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Triple blind (participant, care provider, outcomes assessor)
Number of arms: 2

Arm	Type	Receives
SERRATUS ANTERİOR PLANE BLOCK	Experimental	Procedure: Ultrasound guided serratus anterior plane blockParticipants received an ultrasound-guieded serratus anterior plane block (SAPB)
SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK	Experimental	Procedure: Ultrasound guided serratus posterior superior intercostal plane blockParticipants received an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB)

Who may qualify

Ages: 18 to 65 years
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (1 listed)

Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent

Key exclusion criteria (11 listed)

History of allergy or toxicity to local anesthetic agents
Known or suspected coagulopathy
Infection at the site of block injection
Advanced organ failure
Diagnosed mental retardation

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Ultrasound guided serratus anterior plane blockAlso: serratus anterior plane blockUltrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral)	Procedure or surgery	SERRATUS ANTERİOR PLANE BLOCK
Ultrasound guided serratus posterior superior intercostal plane blockAlso: Serratus posterior superior intercostal plane blockUltrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral)	Procedure or surgery	SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK

Primary outcome

Postoperative pain intensity
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain

5 secondary outcomes

Postoperative pain intensity assessed by Numeric Rating Scale (NRS)
Time frame: 30 minutes, 1, 4, 8, 12, 24 hours after surgery
Total 24-hour tramadol consumption
Time frame: 24 hours after surgery
Rescue analgesia requirement
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Adverse events
Time frame: Within 24 hours after surgery
Dynamic (movement-associated) postoperative pain intensity
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 12 Aug 2026.
Individual participant dataSharing planned: No

Related trials for VATS

Recruiting
ITPB 1 vs 3 in VATS
Musculoskeletal Diseases or Conditions
Not yet recruiting
TBLC vs NIVATS in Interstitial Lung Disease
Interstitial Lung Diseases (ILD)
RecruitingPhase 4
VATS or Intrapleural Enzymatic Therapy for Patients With Empyema.
Empyema, Pleural, Pleural Infections
RecruitingObservational study
Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Op Pain Management After VATS Lung Resection
Thoracic Surgery, Video-assisted
Not yet recruiting
Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung Resection
Thoracic Neoplasms

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Postoperative pain intensity (time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07395661.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Aug 2026.