Eye-trackingECoS-ANCT07377227
Social COgnition Screening
A study testing eye-tracking and cognitive assessments in people with Eye-tracking and Autism Spectrum Disorder, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
Social cognition refers to the mental processes involved in social interactions, including social perception, motivation, communication, emotion recognition, and theory of mind. Face perception plays a key role in children's social development, but children with Autism Spectrum Disorder (ASD) tend to look less at… Read more about this study
- Who is it for?
- Ages 4 to 10 yearsHealthy volunteers can take part
- Conditions the study is for
- Eye-tracking, Autism Spectrum Disorder, Social Cognition
- What is being tested?
- eye-tracking and cognitive assessments
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 128 participants
- Where
- 1 siteFrance
- Study dates
- Feb 2026to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 4 to 10 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- ASD Group:
- Boys or girls diagnosed with Autism Spectrum Disorder (based on clinical tools and observations)
- Aged between 4 and 10 years old
- Affiliation with a social security scheme
- Informed consent of those with parental authority
- DT Group:
Show all 11Show fewer
- Boys or girls
- Aged between 4 and 10
- Attending school in the Hauts-de-France region
- Affiliation with a social security scheme
- Consent of those with parental authority
Who cannot join
- For ASD: Uncorrected visual or auditory impairments.
- For DT: Intellectual disability, neurological or genetic disorders, autistic traits reported by teachers. The discrepancy between actual age and abilities calculated on the basis of standardised test scores
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site
Amiens hospital
Amiens, 80000
Federica Cilia, MD, 33+3 22 66 75 40, Cilia.Federica-ext@chu-amiens.fr
Sébastien Garny De La Rivière, MD
About this study
Official title: Evaluation of Social Cognition: A New Screening Approach for Autism
Social cognition refers to the mental processes involved in social interactions, including social perception, motivation, communication, emotion recognition, and theory of mind. Face perception plays a key role in children's social development, but children with Autism Spectrum Disorder (ASD) tend to look less at social stimuli, especially faces, than typically developing (TD) peers. Eye-tracking studies highlight these visual exploration differences, linked to difficulties in joint attention, emotion recognition, and theory of mind, as well as in executive and memory functions. Standard diagnostic tests often require active participation and sufficient language, which makes assessment challenging for children with ASD and additional cognitive or language impairments.
This research project investigates how visual activity supports social cognition depending on cognitive and language levels, hypothesizing that eye-tracking can provide useful indicators for ASD screening and diagnosis.
- Conditions
- Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis
- Being tested
- eye-tracking, cognitive assessments
- Keywords
- Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis
- Medical subject headings
- Autism Spectrum Disorder, Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
eye-trackingOther
eye-tracking
cognitive assessmentsOther
cognitive assessments
| Study group | Role | What they receive |
|---|---|---|
| Autism Spectrum Disorder | Experimental | Autism Spectrum Disorder Receives: Other: eye-tracking; Other: cognitive assessments |
| typically developing peers | Active comparator | typically developing (TD) peers Receives: Other: eye-tracking; Other: cognitive assessments |
What is being measured
The primary outcome is the main question the study is designed to answer.
differences in visual exploration patterns between both groups
Differences in visual exploration patterns between both groups Visual exploration patterns are determined with TOM Test Battery, PPVT-5, Raven's 2 and FEE tests
Measured: 2 years
Classification performance of machine learning algorithms in distinguishing ASD from TD
Classification performance of machine learning algorithms in distinguishing ASD from TD
Measured: 2 years
Secondary outcomes (3)
Correlations between eye-tracking measures and cognitive scores
Eye-tracking patterns are determined with TOM Test Battery, PPVT-5, Raven's 2 and FEE tests
Measured: 2 years
Developmental trajectory analysis in TD children
Measured: 2 years
Identification of cognitive subgroups within ASD group
Measured: 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jan 2026
- Study startFeb 2026 (estimated)
- Primary completionDec 2027 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Eye-trackingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 128 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07377227
- Sponsor's protocol ID
- PI2025_843_0181
- Acronym
- ECoS-A
- Status last verified
- Feb 2026
- First submitted
- 17 Nov 2025
- Last updated
- 6 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Social Cognition: A New Screening Approach for Autism
- ClinicalTrials.gov ID
- NCT07377227
- Acronym / sponsor ID
- ECoS-A / PI2025_843_0181
- Conditions
- Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis
- Keywords
- Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 128 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- Feb 2026 (estimated)
- Primary completion
- Dec 2027 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 29 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Social cognition refers to the mental processes involved in social interactions, including social perception, motivation, communication, emotion recognition, and theory of mind. Face perception plays a key role in children's social development, but children with Autism Spectrum Disorder (ASD) tend to look less at social stimuli, especially faces, than typically developing (TD) peers. Eye-tracking studies highlight these visual exploration differences, linked to difficulties in joint attention, emotion recognition, and theory of mind, as well as in executive and memory functions. Standard diagnostic tests often require active participation and sufficient language, which makes assessment challenging for children with ASD and additional cognitive or language impairments.
This research project investigates how visual activity supports social cognition depending on cognitive and language levels, hypothesizing that eye-tracking can provide useful indicators for ASD screening and diagnosis.
Study design
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Autism Spectrum Disorder | Experimental | Other: eye-tracking, Other: cognitive assessmentsAutism Spectrum Disorder |
| typically developing peers | Active comparator | Other: eye-tracking, Other: cognitive assessmentstypically developing (TD) peers |
Who may qualify
- Ages
- 4 to 10 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (11 listed)
- ASD Group:
- Boys or girls diagnosed with Autism Spectrum Disorder (based on clinical tools and observations)
- Aged between 4 and 10 years old
- Affiliation with a social security scheme
- Informed consent of those with parental authority
Key exclusion criteria (2 listed)
- For ASD: Uncorrected visual or auditory impairments.
- For DT: Intellectual disability, neurological or genetic disorders, autistic traits reported by teachers. The discrepancy between actual age and abilities calculated on the basis of standardised test scores
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| eye-trackingeye-tracking | Other | Autism Spectrum Disorder, typically developing peers |
| cognitive assessmentscognitive assessments | Other | Autism Spectrum Disorder, typically developing peers |
Primary outcome
differences in visual exploration patterns between both groups
Time frame: 2 years
Differences in visual exploration patterns between both groups Visual exploration patterns are determined with TOM Test Battery, PPVT-5, Raven's 2 and FEE tests
Classification performance of machine learning algorithms in distinguishing ASD from TD
Time frame: 2 years
Classification performance of machine learning algorithms in distinguishing ASD from TD
3 secondary outcomes
Correlations between eye-tracking measures and cognitive scores
Time frame: 2 years
Developmental trajectory analysis in TD children
Time frame: 2 years
Identification of cognitive subgroups within ASD group
Time frame: 2 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing eye-tracking and cognitive assessments in people with Eye-tracking and Autism Spectrum Disorder, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Federica Cilia, MD (33+3 22 66 75 40, Cilia.Federica-ext@chu-amiens.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
differences in visual exploration patterns between both groups (time frame: 2 years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.