Coronary Artery Bypass Graft (CABG)IS/ IMTNCT07367945
Incentive Spirometry Versus Inspiratory Muscle Training After Coronary Artery Bypass Grafting
A study testing Incentive spirometry, Inspiratory muscle trainer and Routine physical therapy in people with Coronary Artery Bypass Graft (CABG), run by Cairo University at 1 site in Egypt.
Trial summary
This study will be conducted to compare between incentive spirometry verses inspiratory muscle training preoperatively on (ABG) after coronary artery bypass graft surgery. Is there any significant difference of preoperative incentive spirometry verses inspiratory muscle training on Arterial blood gases (ABG) after… Read more about this study
- Who is it for?
- Ages 50 to 60 years, men only
- Conditions the study is for
- Coronary Artery Bypass Graft (CABG)
- What is being tested?
- Incentive spirometry, Inspiratory muscle trainer and Routine physical therapy
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Feb 2026to 1 May 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 60 years
- Men only
- No healthy volunteers
- Adult
Who may be able to join
- 45 male patients will be included in this study.
- Patients with age from 50 to 60 years old (undergoing coronary artery bypass graft surgery) through median sternotomy.
- Their body mass index from 25 to 29.9 kg/m2
- Patients will be alert and able to follow instruction.
Who cannot join
- Who are expected not to be able to conduct or comply with IS and IMT.
- Patients with cognitive or neurological deficits.
- Patients with coexisting acute or chronic respiratory disorders.
- Patients unable to understand or show the proper use of the incentive spirometer and Inspiratory muscle training .
- Patients who cannot be instructed or supervised to assure appropriate use of the device patients in whom cooperation is absent or patients unable to understand or demonstrate proper use of the devices (inspiratory muscle training and incentive spirometry).
- Patients who are confused or delirious.
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- Patients undergoing any other surgery along with CABG.
- Patients undergoing emergency CABG surgery.
- Chronic obstructive pulmonary disease (COPD), asthma, restrictive lung disease, preoperative major chest infection e.g. pulmonary tuberculosis, chest deformities such as pectus carinatum, pectus excavatum, thoracolumbar scoliosis, diaphragmatic hernias diagnosed on history.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Preoperative Incentive Spirometry Versus Inspiratory Muscle Training on Arterial Blood Gases After Coronary Artery Bypass Grafting
This study will be conducted to compare between incentive spirometry verses inspiratory muscle training preoperatively on (ABG) after coronary artery bypass graft surgery.
Is there any significant difference of preoperative incentive spirometry verses inspiratory muscle training on Arterial blood gases (ABG) after coronary artery bypass graft surgery?
Participants will:
Group A (incentive spirometry group ) Group B (Inspiratory muscle trainer group ) for 5 days before operative Group C (control group) and group a , b will have routinely postoperative
- Conditions
- Coronary Artery Bypass Graft (CABG)
- Being tested
- Incentive spirometry, Inspiratory muscle trainer, Routine physical therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Incentive spirometryDevice
Also called IS
This group will include 15 patients, Incentive spirometry was utilized by the patient with ten breaths, six sets per day for a period of 10 min within patient tolerance in every session for five days with routinely physical therapy program (education and explanation) preoperatively, And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization).
Inspiratory muscle trainerDevice
Also called IMT
This group will include 15 patients, each session consisted of 30 minutes of inspiratory muscle training. The patients were trained to use an inspiratory threshold-loading device (Threshold Inspiratory Muscle Training) for five days with routinely physical therapy program (education and explanation) preoperatively, And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization).
Routine physical therapyOther
Also called Control group
15 patients will receive for 5 days routinely physical therapy program (education and explanation) preoperatively, And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization).
| Study group | Role | What they receive |
|---|---|---|
| IS | Experimental | This group will include 15 patients, Incentive spirometry was utilized by the patient with ten breaths, six sets per day for a period of 10 min within patient tolerance in every session for five days with routinely physical therapy program (education and explanation) preoperatively, And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization). Receives: Device: Incentive spirometry |
| IMT | Experimental | This group will include 15 patients, each session consisted of 30 minutes of inspiratory muscle training. The patients were trained to use an inspiratory threshold-loading device (Threshold Inspiratory Muscle Training) for five days with routinely physical therapy program (education and explanation) preoperatively, two times per day.
And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization). Receives: Device: Inspiratory muscle trainer |
| Control group | Active comparator | 15 patients will receive for 5 days routinely physical therapy program (education and explanation) preoperatively, And postoperatively treatment (breathing treatment, deep-breathing applications, guided coughing, early mobilization). Receives: Other: Routine physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Arterial Blood gas Parameters (PaO2 and SaO2)
Assessment of arterial oxygenation changes by measuring PaO2 and SaO2 . data will be collected at Baseline pre-surgery (5 days ) , Immediately after the surgery (within 48 hours) , and through study completion an average of 8 days. to evaluate the recovery trend and the effectiveness of respiratory interventions.
Measured: Baseline 5 days pre-surgery , Immediately after the surgery within 48 hours , and through study completion an average of 8 days.
Numerical rating pain scale
Pain Scale for Pain Assessment. data will be collected at Baseline pre-surgery (5 days ) , Immediately after the surgery (within 48 hours) , and through study completion an average of 8 days. to evaluate the recovery trend and the effectiveness of respiratory interventions.
Measured: Baseline 5 days pre-surgery , Immediately after the surgery within 48 hours , and through study completion an average of 8 days.
Secondary outcomes (2)
Functional capacity (2- minute walk test)
measuring the maximum distance a patient can walk on a flat surface in 2-minutes to evaluate functional exercise capacity.
Measured: Baseline 5 days pre-surgery, and through study completion an average of 8 days.
Physical function ICU test - scored (PFIT-s)
Assessment of physical function in the ICU through four components ( sit -to- stand, marching, shoulder flexion, and knee extension ) Scored (0 - 10).
Measured: Immediately after the surgery within 48 hours.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jan 2026
- Study start1 Feb 2026
- Primary completion1 May 2026
- Study completion1 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Coronary Artery Bypass Graft (CABG)Studies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eman Abdelmohsen Ismail Hassan, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07367945
- Sponsor's protocol ID
- P.T.REC/012/006065
- Acronym
- IS/ IMT
- Status last verified
- Dec 2025
- First submitted
- 6 Jan 2026
- Last updated
- 1 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: data is available with a corresponding offer on reasonable request