HealthyNCT07367607
Circadian Modulation of Neurophysiological Responses to Therapeutic Massage Modalities
A study testing FMP, VMMP and PMMP in people with Healthy, run by Princess Nourah Bint Abdulrahman University at 1 site in Turkey (Türkiye).
Trial summary
Athletic performance and recovery are closely linked to central nervous system regulation, which can be objectively assessed using electroencephalography (EEG). Although therapeutic massage is widely used as a recovery modality in combat sports, its neurophysiological effects and potential interaction with circadian… Read more about this study
- Who is it for?
- Ages 18 to 25 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- FMP, VMMP and PMMP
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 12 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Aug 2025to 5 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Male taekwondo athletes aged 18-25 years
- Minimum of 4 years of structured taekwondo training
- Training frequency ≥ 5 days/week
- Black belt (1st Dan or higher)
- No musculoskeletal injury in the past 6 months
Who cannot join
- Neurological or psychiatric disorders
- Use of stimulant substances or anti-inflammatory medication
- Irregular sleep-wake patterns (e.g., shift work)
- Withdrawal of consent at any stage
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Faculty of Sport Sciences, İnönü University
Malatya
About this study
Official title: Circadian Modulation of Neurophysiological Responses to Therapeutic Massage Modalities in Taekwondo Athletes: A Randomized Crossover Trial
Athletic performance and recovery are closely linked to central nervous system regulation, which can be objectively assessed using electroencephalography (EEG). Although therapeutic massage is widely used as a recovery modality in combat sports, its neurophysiological effects and potential interaction with circadian timing remain poorly understood. This study investigates whether different therapeutic massage modalities applied at different times of the day modulate resting-state EEG activity in taekwondo athletes.
Read the detailed description
This randomized, within-subject crossover study examines the effects of different therapeutic massage modalities and time of day on resting-state EEG activity in elite male taekwondo athletes. Twelve athletes complete four experimental conditions: no-massage control, friction massage, vibration mechanical massage, and percussion mechanical massage. Each condition is administered during both morning and evening sessions, separated by a minimum 48-hour washout period.
Resting-state EEG is recorded immediately following each intervention using a 32-channel system. Power spectral density is computed to extract global band power in delta, theta, alpha, beta, and gamma frequency bands. The study aims to determine whether massage modality, circadian timing, or their interaction significantly influences cortical oscillatory activity associated with recovery and neural readiness.
- Conditions
- Healthy
- Being tested
- FMP, VMMP, PMMP
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
FMPBehavioural
Manual therapeutic massage consisting of rhythmic, sustained friction techniques applied by a certified physiotherapist to the dominant upper extremity muscles. Moderate-to-strong pressure was applied for a total duration of 10 minutes using a standardized intermittent protocol.
VMMPDevice
Therapeutic vibration massage delivered using a handheld vibration device set at a fixed frequency of 50 Hz. The device was applied to the dominant upper extremity muscles for 10 minutes to provide localized high-frequency mechanical stimulation.
PMMPDevice
Therapeutic percussion massage administered using a handheld percussive therapy device delivering rapid mechanical impulses at approximately 40 Hz. The intervention was applied to the dominant upper extremity muscles for 10 minutes to elicit deep somatosensory stimulation.
| Study group | Role | What they receive |
|---|---|---|
| Friction Massage (FMP) | Experimental | Not described Receives: Behavioral: FMP |
| Vibration Mechanical Massage (VMMP) | Experimental | Not described Receives: Device: VMMP |
| Percussion Mechanical Massage (PMMP) | Experimental | Not described Receives: Device: PMMP |
What is being measured
The primary outcome is the main question the study is designed to answer.
Global EEG Band Power
Log-transformed power spectral density values for delta, theta, alpha, beta, and gamma frequency bands obtained from resting-state EEG recordings.
Measured: Immediately post-intervention in morning and evening sessions.
Secondary outcomes (1)
Topographical EEG Distribution
Spatial distribution of EEG band power across frontal and central scalp regions.
Measured: Immediately post-intervention in morning and evening sessions.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jan 2026
- Study start1 Aug 2025
- Primary completion1 Jan 2026
- Study completion5 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 12 participants (actual)
Sponsor and investigators
- Lead sponsor
- Princess Nourah Bint Abdulrahman University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Monira Aldhahi, Princess Nourah Bint Abdulrahman University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07367607
- Sponsor's protocol ID
- PNU-10
- Status last verified
- Jan 2026
- First submitted
- 17 Jan 2026
- Last updated
- 26 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 26 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Circadian Modulation of Neurophysiological Responses to Therapeutic Massage Modalities in Taekwondo Athletes: A Randomized Crossover Trial
- ClinicalTrials.gov ID
- NCT07367607
- Acronym / sponsor ID
- PNU-10
- Conditions
- Healthy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 12 participants (actual)
- Lead sponsor
- Princess Nourah Bint Abdulrahman UniversityUniversity, hospital or other
- Study start
- 1 Aug 2025 (actual)
- Primary completion
- 1 Jan 2026 (actual)
- Study completion
- 5 Jan 2026 (actual)
- First posted
- 26 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Athletic performance and recovery are closely linked to central nervous system regulation, which can be objectively assessed using electroencephalography (EEG). Although therapeutic massage is widely used as a recovery modality in combat sports, its neurophysiological effects and potential interaction with circadian timing remain poorly understood. This study investigates whether different therapeutic massage modalities applied at different times of the day modulate resting-state EEG activity in taekwondo athletes.
Detailed description
This randomized, within-subject crossover study examines the effects of different therapeutic massage modalities and time of day on resting-state EEG activity in elite male taekwondo athletes. Twelve athletes complete four experimental conditions: no-massage control, friction massage, vibration mechanical massage, and percussion mechanical massage. Each condition is administered during both morning and evening sessions, separated by a minimum 48-hour washout period.
Resting-state EEG is recorded immediately following each intervention using a 32-channel system. Power spectral density is computed to extract global band power in delta, theta, alpha, beta, and gamma frequency bands. The study aims to determine whether massage modality, circadian timing, or their interaction significantly influences cortical oscillatory activity associated with recovery and neural readiness.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Friction Massage (FMP) | Experimental | Behavioral: FMP |
| Vibration Mechanical Massage (VMMP) | Experimental | Device: VMMP |
| Percussion Mechanical Massage (PMMP) | Experimental | Device: PMMP |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Male taekwondo athletes aged 18-25 years
- Minimum of 4 years of structured taekwondo training
- Training frequency ≥ 5 days/week
- Black belt (1st Dan or higher)
- No musculoskeletal injury in the past 6 months
Key exclusion criteria (4 listed)
- Neurological or psychiatric disorders
- Use of stimulant substances or anti-inflammatory medication
- Irregular sleep-wake patterns (e.g., shift work)
- Withdrawal of consent at any stage
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| FMPManual therapeutic massage consisting of rhythmic, sustained friction techniques applied by a certified physiotherapist to the dominant upper extremity muscles. Moderate-to-strong pressure was applied for a total duration of 10 minutes using a standardized intermittent protocol. | Behavioural | Friction Massage (FMP) |
| VMMPTherapeutic vibration massage delivered using a handheld vibration device set at a fixed frequency of 50 Hz. The device was applied to the dominant upper extremity muscles for 10 minutes to provide localized high-frequency mechanical stimulation. | Device | Vibration Mechanical Massage (VMMP) |
| PMMPTherapeutic percussion massage administered using a handheld percussive therapy device delivering rapid mechanical impulses at approximately 40 Hz. The intervention was applied to the dominant upper extremity muscles for 10 minutes to elicit deep somatosensory stimulation. | Device | Percussion Mechanical Massage (PMMP) |
Primary outcome
Global EEG Band Power
Time frame: Immediately post-intervention in morning and evening sessions.
Log-transformed power spectral density values for delta, theta, alpha, beta, and gamma frequency bands obtained from resting-state EEG recordings.
1 secondary outcome
Topographical EEG Distribution
Time frame: Immediately post-intervention in morning and evening sessions.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jan 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing FMP, VMMP and PMMP in people with Healthy, run by Princess Nourah Bint Abdulrahman University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Global EEG Band Power (time frame: Immediately post-intervention in morning and evening sessions.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jan 2026.