AnesthesiaASGARD-igelNCT07338448
Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation
A study testing transcutaneous electrical acupoint stimulation and electrodes attachment in people with Anesthesia, run by Air Force Military Medical University, China.
Trial summary
This study will compare the effects of transcutaneous acupoint electrical stimulation versus no stimulation on intraoperative gastric reflux in patients undergoing general anesthesia with i-gel airway device ventilation. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Anesthesia
- What is being tested?
- transcutaneous electrical acupoint stimulation and electrodes attachment
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 116 participants
- Where
- No sites listed yet
- Study dates
- 12 Jan 2026to 31 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- age ≥18 years old
- scheduled for surgery under general anesthesia with igel ventilation
Who cannot join
- American society of anesthesiologists status higher than grade 3
- history of gastrointestinal surgery
- Currently taking acidic medications, or medications that affect gastric acid secretion or gastrointestinal motility
- High risk of reflux or aspiration (e.g., symptomatic gastroesophageal reflux disease or hiatal hernia)
- History of postoperative nausea and vomiting (PONV)
- Intraoperative requirement of Trendelenburg position
- Expected surgery duration exceeding 4 hours
- Contraindications for acupoint electrical stimulation, such as patients with implanted electrophysiological devices, or skin infection/lesions at acupoint sites
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effect of Electrical Acupoint Stimulation on Gastric Reflux During Anesthesia With I-gel Ventilation
This study will compare the effects of transcutaneous acupoint electrical stimulation versus no stimulation on intraoperative gastric reflux in patients undergoing general anesthesia with i-gel airway device ventilation.
- Conditions
- Anesthesia
- Being tested
- transcutaneous electrical acupoint stimulation, electrodes attachment
- Keywords
- acupoint stimulation, general anesthesia, gastric reflux, igel
- Medical subject headings
- Gastroesophageal Reflux, Ige Responsiveness, Atopic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
transcutaneous electrical acupoint stimulationOther
electrical stimulation at 2Hz/10Hz is given from induction to end of surgery
electrodes attachmentOther
Electrodes are pasted to the skin of Neiguan, Zusanli, Gongsun, Taichong acupoints
| Study group | Role | What they receive |
|---|---|---|
| Electrical stimulation | Experimental | Electrodes are pasted at the Neiguan, Zusanli, Gongsun, Taichong acupoints and electrical stimulation is given from anesthesia induction to end of surgery Receives: Other: transcutaneous electrical acupoint stimulation; Other: electrodes attachment |
| Control | Placebo comparator | Electrodes are pasted at the Neiguan, Zusanli, Gongsun, Taichong acupoints but no electrical stimulation is given Receives: Other: electrodes attachment |
What is being measured
The primary outcome is the main question the study is designed to answer.
pH value at middle-esophageal part at end of surgery
Measured: at end of surgery
Secondary outcomes (5)
number of gastric reflux episodes
Measured: from intubation of igel to end of surgery, at an average of 2 hours
total duration of gastric reflux episodes
Measured: from intubation of igel to end of surgery, at an average of 2 hours
longest duration of gastric reflux episodes
Measured: from intubation of igel to end of surgery, at an average of 2 hours
pH value at glottis at the end of surgery
Measured: at end of surgery
percentage of patients suffering postoperative nausea and vomiting by 24 hours after surgery
Measured: from end of surgery to 24 hours after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jan 2026
- Study start12 Jan 2026 (estimated)
- Primary completion31 Jul 2026 (estimated)
- Study completion31 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnesthesiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 116 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Air Force Military Medical University, China
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zhihong LU, Air Force Military Medical University, China
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07338448
- Sponsor's protocol ID
- XJH-A-20251021
- Acronym
- ASGARD-igel
- Status last verified
- Jan 2026
- First submitted
- 3 Jan 2026
- Last updated
- 13 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 13 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Electrical Acupoint Stimulation on Gastric Reflux During Anesthesia With I-gel Ventilation
- ClinicalTrials.gov ID
- NCT07338448
- Acronym / sponsor ID
- ASGARD-igel / XJH-A-20251021
- Conditions
- Anesthesia
- Keywords
- acupoint stimulation, general anesthesia, gastric reflux, igel
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 116 participants (estimated)
- Lead sponsor
- Air Force Military Medical University, ChinaUniversity, hospital or other
- Study start
- 12 Jan 2026 (estimated)
- Primary completion
- 31 Jul 2026 (estimated)
- Study completion
- 31 Jul 2026 (estimated)
- First posted
- 13 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will compare the effects of transcutaneous acupoint electrical stimulation versus no stimulation on intraoperative gastric reflux in patients undergoing general anesthesia with i-gel airway device ventilation.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Electrical stimulation | Experimental | Other: transcutaneous electrical acupoint stimulation, Other: electrodes attachmentElectrodes are pasted at the Neiguan, Zusanli, Gongsun, Taichong acupoints and electrical stimulation is given from anesthesia induction to end of surgery |
| Control | Placebo comparator | Other: electrodes attachmentElectrodes are pasted at the Neiguan, Zusanli, Gongsun, Taichong acupoints but no electrical stimulation is given |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- age ≥18 years old
- scheduled for surgery under general anesthesia with igel ventilation
Key exclusion criteria (8 listed)
- American society of anesthesiologists status higher than grade 3
- history of gastrointestinal surgery
- Currently taking acidic medications, or medications that affect gastric acid secretion or gastrointestinal motility
- High risk of reflux or aspiration (e.g., symptomatic gastroesophageal reflux disease or hiatal hernia)
- History of postoperative nausea and vomiting (PONV)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| transcutaneous electrical acupoint stimulationelectrical stimulation at 2Hz/10Hz is given from induction to end of surgery | Other | Electrical stimulation |
| electrodes attachmentElectrodes are pasted to the skin of Neiguan, Zusanli, Gongsun, Taichong acupoints | Other | Control, Electrical stimulation |
Primary outcome
pH value at middle-esophageal part at end of surgery
Time frame: at end of surgery
5 secondary outcomes
number of gastric reflux episodes
Time frame: from intubation of igel to end of surgery, at an average of 2 hours
total duration of gastric reflux episodes
Time frame: from intubation of igel to end of surgery, at an average of 2 hours
longest duration of gastric reflux episodes
Time frame: from intubation of igel to end of surgery, at an average of 2 hours
pH value at glottis at the end of surgery
Time frame: at end of surgery
percentage of patients suffering postoperative nausea and vomiting by 24 hours after surgery
Time frame: from end of surgery to 24 hours after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Jan 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing transcutaneous electrical acupoint stimulation and electrodes attachment in people with Anesthesia, run by Air Force Military Medical University, China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Zhihong Lu (86-13891975018, deerlu23@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
pH value at middle-esophageal part at end of surgery (time frame: at end of surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jan 2026.