Hand and Forearm TraumaNCT07326943
Minimum Effective Dose of Ropivacaine for Ultrasound-guided Interscalene Block
A study testing Ultrasound guided intermuscular groove block targeting the C7 nerve root in people with Hand and Forearm Trauma and Hand and Forearm Diseases, run by Huazhong University of Science and Technology at 1 site in China.
Trial summary
Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Hand and Forearm Trauma, Hand and Forearm Diseases
- What is being tested?
- Ultrasound guided intermuscular groove block targeting the C7 nerve root
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 siteChina
- Study dates
- 1 May 2026to 30 Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age range: 18-60 years old
- ASAⅠ~II
- BMI between 18 and 30kg/m2
- Patients undergoing hand or forearm surgery
- Sign informed consent form
Who cannot join
- Refusal to participate in the experiment
- Merge peripheral nerve diseases
- Lidocaine and ropivacaine allergy
- Pregnant women
- Obstructive or restrictive lung disease
- Coagulation dysfunction
- Long term use of opioid drugs
- Infection, tumor or surgical history at the puncture site
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Zheng Hua, Study Principal Investigator contact
China1 site, 1 recruiting
- Recruiting
Shanxi Bethune Hospital
Taiyuan, Shanxi, 030032
Xiaomin zhang, 8618435148730, sxdyyky@126.com
About this study
Official title: Minimum Effective Dose of Ropivacaine 0.5% for Ultrasound-guided Interscalene Block Targeting the C7 Nerve Root in Hand and Forearm Surgery
Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. The classic ultrasound-guided intermuscular groove block also involves puncturing the needle to the level of the C5/C6 anterior branch for drug injection. After injection, local anesthetics mainly wrap around C5, C6, and some C7 nerve roots. Therefore, intermuscular groove block is mainly used for shoulder, humerus, and clavicle surgery. Due to incomplete ulnar block, it is not recommended for surgery on the elbow joint and its distal end.Scholars have found that using C5 as the puncture target to implement intermuscular groove block and administering 10ml of 0.75% ropivacaine, the success rate of ulnar nerve block is 19%. The success rate of ulnar nerve block with C6 as the puncture target was 93% when 10ml of 0.75% ropivacaine was administered. This suggests that blockade methods closer to the tail muscle groove on the tail side have a higher success rate for blocking the C7, C8, and T1 nerve roots. In our clinical work, the investigators found that when performing intermuscular groove block with C7 nerve root as the puncture target, local anesthetics not only stably wrap around C7 nerve root, but also spread to wrap around C5 and C6 nerve roots on the head side, and spread to the deep surface of the brachial plexus trunk on the tail side. Local anesthetic diffusion can also be seen in some patients at the brachial plexus bundle in the intercostal space. From the perspective of local anesthetic diffusion patterns, intermuscular groove block targeting the C7 nerve root may cover the anterior branches of C5, C6, C7, C8, and T1 nerve roots, achieving complete brachial plexus block. Preliminary clinical practice suggests that C7 intermuscular groove block can be used for forearm and hand surgery. Successful C7 intermuscular groove block relies on the diffusion and wrapping of local anesthetics around the anterior branches of C5, C6, and C7 nerve roots, as well as the inferior trunk of the brachial plexus (or the anterior branches of C8 and T1 nerve roots).Therefore, the investigators designed this study to determine the amount of local anesthetic required to achieve stable forearm and hand block during C7 intermuscular groove block.
Read the detailed description
Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. Intermuscular groove block is achieved by injecting local anesthetics between the anterior and middle scalene muscles in order to block the anterior branches of the cervical nerve that pass through this gap, including the anterior branches of the cervical 5 (C5), cervical 6 (C6), and cervical 7 (C7) spinal nerves. The classic technique of intermuscular groove block involves puncturing the thyroid cartilage horizontally into the intermuscular groove. This area is roughly equivalent to the level of the anterior branch of the C5/C6 nerve root. The classic ultrasound-guided intermuscular groove block also involves puncturing the needle to the level of the C5/C6 anterior branch for drug injection. After injection, local anesthetics mainly wrap around C5, C6, and some C7 nerve roots. According to the range of spinal nerve innervation, its blocking range is located in the shoulder, the anterior, posterior, and lateral sides of the upper arm, the anterior, posterior, and lateral sides of the forearm, and the two and a half fingers on the radial side. Therefore, intermuscular groove block is mainly used for shoulder, humerus, and clavicle surgery. Due to incomplete ulnar block, it is not recommended for surgery on the elbow joint and its distal end.Scholars have found that using C5 as the puncture target to implement intermuscular groove block and administering 10ml of 0.75% ropivacaine, the success rate of ulnar nerve block is 19%. The success rate of ulnar nerve block with C6 as the puncture target was 93% when 10ml of 0.75% ropivacaine was administered. This suggests that blockade methods closer to the tail muscle groove on the tail side have a higher success rate for blocking the C7, C8, and T1 nerve roots. In our clinical work, the investigators found that when performing intermuscular groove block with C7 nerve root as the puncture target, local anesthetics not only stably wrap around C7 nerve root, but also spread to wrap around C5 and C6 nerve roots on the head side, and spread to the deep surface of the brachial plexus trunk on the tail side. Local anesthetic diffusion can also be seen in some patients at the brachial plexus bundle in the intercostal space. From the perspective of local anesthetic diffusion patterns, intermuscular groove block targeting the C7 nerve root may cover the anterior branches of C5, C6, C7, C8, and T1 nerve roots, achieving complete brachial plexus block. In the preliminary exploratory clinical work, the patient underwent C7 nerve root intermuscular groove brachial plexus block. Through sensory testing, it was found that the musculocutaneous nerve, medial forearm nerve, radial nerve, median nerve, and ulnar nerve could all be stably blocked, and the forearm and hand surgeries were successfully completed under nerve block. Preliminary clinical practice suggests that C7 intermuscular groove block can be used for forearm and hand surgery. Successful C7 intermuscular groove block relies on the diffusion and wrapping of local anesthetics around the anterior branches of C5, C6, and C7 nerve roots, as well as the inferior trunk of the brachial plexus (or the anterior branches of C8 and T1 nerve roots).Therefore, the investigators designed this study to determine the amount of local anesthetic required to achieve stable forearm and hand block during C7 intermuscular groove block.
- Conditions
- Hand and Forearm Trauma, Hand and Forearm Diseases
- Being tested
- Ultrasound guided intermuscular groove block targeting the C7 nerve root
- Keywords
- ultrasound-guided interscalene block, Minimum effective dose, C7 nerve root
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound guided intermuscular groove block targeting the C7 nerve rootProcedure or surgery
The patient will receive ultrasound-guided intermuscular groove brachial plexus block targeting the C7 nerve root, decreasing doses of ropivacaine 0.5% will be administered.
Ultrasound guided intermuscular groove block targeting the C7 nerve rootProcedure or surgery
The patient will receive ultrasound-guided intermuscular groove brachial plexus block targeting the C7 nerve root, similar doses of ropivacaine 0.5% will be administered.
| Study group | Role | What they receive |
|---|---|---|
| Deceasing | Experimental | Brachial plexus block with decreasing dose. Real time ultrasound-guided intermuscular brachial plexus block anesthesia targeting the C7 nerve root. Receives: Procedure: Ultrasound guided intermuscular groove block targeting the C7 nerve root |
| similar | Experimental | Brachial plexus block, with similar doses. Real time ultrasound-guided intermuscular brachial plexus block anesthesia for C7 nerve roots Receives: Procedure: Ultrasound guided intermuscular groove block targeting the C7 nerve root |
What is being measured
The primary outcome is the main question the study is designed to answer.
Assessment of blocking effect
Starting from the completion of the nerve block, an independent evaluator (unaware of the dosage used) will test and record the block effect at 10, 20, and 30 minutes after the block. The block effect will be judged based on the effect at 30 minutes. Conduct sensory tests on the skin innervated by various nerves using ice cubes. Use a 3-point numerical scale (0=normal cold sensation, no obstruction; 1=partial cold sensation, partial obstruction; 2=no cold sensation, complete obstruction). Radial nerve, median nerve, ulnar nerve, musculocutaneous nerve, and medial forearm cutaneous nerve. Evaluate the degree of motor block through specific exercise activities (0=normal activity, 1=partial block, 2=complete block). Patients who are fully awake or have been administered an appropriate amount of sedatives, maintain spontaneous breathing, and successfully complete the surgery are considered to have successful blockade (i.e. positive reaction).
Measured: From the completion of nerve block to the 30th minute after block
Secondary outcomes (1)
Diaphragmatic muscle movement status
Ultrasound measurement of basal range of motion of the blocked ipsilateral diaphragm: The patient is seated in a semi seated position, with a low-frequency convex array probe placed between the anterior axillary line and the midline of the axilla. Real time M-mode ultrasound is used to evaluate the motion of the ipsilateral diaphragm. Use a low intercostal or subcostal approach, with the liver or spleen as the sound window for scanning. Record the diaphragm movement amplitude during rapid nasal inhalation from the resting exhalation position. Measure three times and take the average. And retain the measured images.
30 minutes after the completion of nerve block, evaluate the patient's diaphragm movement using the same method as before. The degree of diaphragmatic block is defined as a decrease in movement amplitude of>75% (complete diaphragmatic block), a decrease in movement amplitude of 25-75% (partial block), and a decrease of<25% (no block) compared to before the block was impleme
Measured: From the completion of nerve block to the 30th minute after block
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jan 2026
- Study start1 May 2026
- Primary completion30 Dec 2026 (estimated)
- Study completion30 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hand and Forearm TraumaStudies of the same condition, open and under way.
- More trials run by Huazhong University of Science and TechnologyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Model description
- This experiment enrolled participants using a biased coin up and down sequential method. The first subject was given 0.5% ropivacaine 12mL. The subsequent dose of ropivacaine for each subject depends on the anesthetic effect of the previous subject. If the effect of the previous subject is "failure" (negative reaction), the dose of ropivacaine will be increased by 1mL for the next subject. If the effect of the previous subject is "success" (positive reaction), the next subject will be randomized using the partial currency method. The patients will be randomly divided into two groups: one group will receive the same dose of ropivacaine as the previous subject (probability B=0.89) (same dose group); The dose of ropivacaine in another group decreased by 1mL (probability 1-B=0.11). The criterion for successful blockade is to simultaneously meet the following two criteria: (1) disappearance of sensory sensation in the muscle cutaneous nerve, medial forearm cutaneous nerve, median nerve, rad
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 56 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Huazhong University of Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hua Zheng, Huazhong University of Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07326943
- Sponsor's protocol ID
- YXLL-2025-292
- Status last verified
- Sep 2026
- First submitted
- 22 Dec 2025
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Paper case report forms were written by hand
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Minimum Effective Dose of Ropivacaine 0.5% for Ultrasound-guided Interscalene Block Targeting the C7 Nerve Root in Hand and Forearm Surgery
- ClinicalTrials.gov ID
- NCT07326943
- Acronym / sponsor ID
- YXLL-2025-292
- Conditions
- Hand and Forearm Trauma, Hand and Forearm Diseases
- Keywords
- ultrasound-guided interscalene block, Minimum effective dose, C7 nerve root
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 56 participants (estimated)
- Lead sponsor
- Huazhong University of Science and TechnologyUniversity, hospital or other
- Study start
- 1 May 2026 (actual)
- Primary completion
- 30 Dec 2026 (estimated)
- Study completion
- 30 Jun 2027 (estimated)
- First posted
- 8 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. The classic ultrasound-guided intermuscular groove block also involves puncturing the needle to the level of the C5/C6 anterior branch for drug injection. After injection, local anesthetics mainly wrap around C5, C6, and some C7 nerve roots. Therefore, intermuscular groove block is mainly used for shoulder, humerus, and clavicle surgery. Due to incomplete ulnar block, it is not recommended for surgery on the elbow joint and its distal end.Scholars have found that using C5 as the puncture target to implement intermuscular groove block and administering 10ml of 0.75% ropivacaine, the success rate of ulnar nerve block is 19%. The success rate of ulnar nerve block with C6 as the puncture target was 93% when 10ml of 0.75% ropivacaine was administered. This suggests that blockade methods closer to the tail muscle groove on the tail side have a higher success rate for blocking the C7, C8, and T1 nerve roots. In our clinical work, the investigators found that when performing intermuscular groove block with C7 nerve root as the puncture target, local anesthetics not only stably wrap around C7 nerve root, but also spread to wrap around C5 and C6 nerve roots on the head side, and spread to the deep surface of the brachial plexus trunk on the tail side. Local anesthetic diffusion can also be seen in some patients at the brachial plexus bundle in the intercostal space. From the perspective of local anesthetic diffusion patterns, intermuscular groove block targeting the C7 nerve root may cover the anterior branches of C5, C6, C7, C8, and T1 nerve roots, achieving complete brachial plexus block. Preliminary clinical practice suggests that C7 intermuscular groove block can be used for forearm and hand surgery. Successful C7 intermuscular groove block relies on the diffusion and wrapping of local anesthetics around the anterior branches of C5, C6, and C7 nerve roots, as well as the inferior trunk of the brachial plexus (or the anterior branches of C8 and T1 nerve roots).Therefore, the investigators designed this study to determine the amount of local anesthetic required to achieve stable forearm and hand block during C7 intermuscular groove block.
Detailed description
Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. Intermuscular groove block is achieved by injecting local anesthetics between the anterior and middle scalene muscles in order to block the anterior branches of the cervical nerve that pass through this gap, including the anterior branches of the cervical 5 (C5), cervical 6 (C6), and cervical 7 (C7) spinal nerves. The classic technique of intermuscular groove block involves puncturing the thyroid cartilage horizontally into the intermuscular groove. This area is roughly equivalent to the level of the anterior branch of the C5/C6 nerve root. The classic ultrasound-guided intermuscular groove block also involves puncturing the needle to the level of the C5/C6 anterior branch for drug injection. After injection, local anesthetics mainly wrap around C5, C6, and some C7 nerve roots. According to the range of spinal nerve innervation, its blocking range is located in the shoulder, the anterior, posterior, and lateral sides of the upper arm, the anterior, posterior, and lateral sides of the forearm, and the two and a half fingers on the radial side. Therefore, intermuscular groove block is mainly used for shoulder, humerus, and clavicle surgery. Due to incomplete ulnar block, it is not recommended for surgery on the elbow joint and its distal end.Scholars have found that using C5 as the puncture target to implement intermuscular groove block and administering 10ml of 0.75% ropivacaine, the success rate of ulnar nerve block is 19%. The success rate of ulnar nerve block with C6 as the puncture target was 93% when 10ml of 0.75% ropivacaine was administered. This suggests that blockade methods closer to the tail muscle groove on the tail side have a higher success rate for blocking the C7, C8, and T1 nerve roots. In our clinical work, the investigators found that when performing intermuscular groove block with C7 nerve root as the puncture target, local anesthetics not only stably wrap around C7 nerve root, but also spread to wrap around C5 and C6 nerve roots on the head side, and spread to the deep surface of the brachial plexus trunk on the tail side. Local anesthetic diffusion can also be seen in some patients at the brachial plexus bundle in the intercostal space. From the perspective of local anesthetic diffusion patterns, intermuscular groove block targeting the C7 nerve root may cover the anterior branches of C5, C6, C7, C8, and T1 nerve roots, achieving complete brachial plexus block. In the preliminary exploratory clinical work, the patient underwent C7 nerve root intermuscular groove brachial plexus block. Through sensory testing, it was found that the musculocutaneous nerve, medial forearm nerve, radial nerve, median nerve, and ulnar nerve could all be stably blocked, and the forearm and hand surgeries were successfully completed under nerve block. Preliminary clinical practice suggests that C7 intermuscular groove block can be used for forearm and hand surgery. Successful C7 intermuscular groove block relies on the diffusion and wrapping of local anesthetics around the anterior branches of C5, C6, and C7 nerve roots, as well as the inferior trunk of the brachial plexus (or the anterior branches of C8 and T1 nerve roots).Therefore, the investigators designed this study to determine the amount of local anesthetic required to achieve stable forearm and hand block during C7 intermuscular groove block.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- This experiment enrolled participants using a biased coin up and down sequential method. The first subject was given 0.5% ropivacaine 12mL. The subsequent dose of ropivacaine for each subject depends on the anesthetic effect of the previous subject. If the effect of the previous subject is "failure" (negative reaction), the dose of ropivacaine will be increased by 1mL for the next subject. If the effect of the previous subject is "success" (positive reaction), the next subject will be randomized using the partial currency method. The patients will be randomly divided into two groups: one group will receive the same dose of ropivacaine as the previous subject (probability B=0.89) (same dose group); The dose of ropivacaine in another group decreased by 1mL (probability 1-B=0.11). The criterion for successful blockade is to simultaneously meet the following two criteria: (1) disappearance of sensory sensation in the muscle cutaneous nerve, medial forearm cutaneous nerve, median nerve, rad
| Arm | Type | Receives |
|---|---|---|
| Deceasing | Experimental | Procedure: Ultrasound guided intermuscular groove block targeting the C7 nerve rootBrachial plexus block with decreasing dose. Real time ultrasound-guided intermuscular brachial plexus block anesthesia targeting the C7 nerve root. |
| similar | Experimental | Procedure: Ultrasound guided intermuscular groove block targeting the C7 nerve rootBrachial plexus block, with similar doses. Real time ultrasound-guided intermuscular brachial plexus block anesthesia for C7 nerve roots |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age range: 18-60 years old
- ASAⅠ~II
- BMI between 18 and 30kg/m2
- Patients undergoing hand or forearm surgery
- Sign informed consent form
Key exclusion criteria (8 listed)
- Refusal to participate in the experiment
- Merge peripheral nerve diseases
- Lidocaine and ropivacaine allergy
- Pregnant women
- Obstructive or restrictive lung disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound guided intermuscular groove block targeting the C7 nerve rootThe patient will receive ultrasound-guided intermuscular groove brachial plexus block targeting the C7 nerve root, decreasing doses of ropivacaine 0.5% will be administered. | Procedure or surgery | Deceasing |
| Ultrasound guided intermuscular groove block targeting the C7 nerve rootThe patient will receive ultrasound-guided intermuscular groove brachial plexus block targeting the C7 nerve root, similar doses of ropivacaine 0.5% will be administered. | Procedure or surgery | similar |
Primary outcome
Assessment of blocking effect
Time frame: From the completion of nerve block to the 30th minute after block
Starting from the completion of the nerve block, an independent evaluator (unaware of the dosage used) will test and record the block effect at 10, 20, and 30 minutes after the block. The block effect will be judged based on the effect at 30 minutes. Conduct sensory tests on the skin innervated by various nerves using ice cubes. Use a 3-point numerical scale (0=normal cold sensation, no obstruction; 1=partial cold sensation, partial obstruction; 2=no cold sensation, complete obstruction). Radial nerve, median nerve, ulnar nerve, musculocutaneous nerve, and medial forearm cutaneous nerve. Evaluate the degree of motor block through specific exercise activities (0=normal activity, 1=partial block, 2=complete block). Patients who are fully awake or have been administered an appropriate amount of sedatives, maintain spontaneous breathing, and successfully complete the surgery are considered to have successful blockade (i.e. positive reaction).
1 secondary outcome
Diaphragmatic muscle movement status
Time frame: From the completion of nerve block to the 30th minute after block
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No. Paper case report forms were written by hand
Related trials for Hand and Forearm Trauma
Not yet recruiting
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
Wrist Injury, Hand and Upper Limb Trauma
Recruiting
Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand Surgery
Hand Injuries and Disorders, Wrist Sprain
RecruitingObservational study
Perceived Ability and Hand Function
Hand Injuries, Forearm Injuries
RecruitingObservational study
Health Literacy Level and Functional Outcomes in Patients With Hand and Forearm Injuries
Hand Injuries, Forearm Fractures
Not yet recruitingObservational study
The Cognitive-Functional Relationship in Geriatric Hand-Forearm Injuries
Geriatric Population, Cognitive Ability
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Zheng Hua, Study Principal Investigator contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound guided intermuscular groove block targeting the C7 nerve root in people with Hand and Forearm Trauma and Hand and Forearm Diseases, run by Huazhong University of Science and Technology at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Huailiang LI, (86+18834183517, 574199674@qq.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Assessment of blocking effect (time frame: From the completion of nerve block to the 30th minute after block). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.