Chronic Mechanical Neck PainNCT07326696
Thoracic Thrust With Cervical Non-Thrust Mobilization in Mechanical Neck Pain
A study testing Group A:Thoracic thrust and Group B: Cervical non thrust mobilization in people with Chronic Mechanical Neck Pain, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
This study is a randomised controlled trial and the purpose of this study is to determine the effects of thoracic thrust with cervical non-thrust mobilization in mechanical neck pain on components such as pain, thoracic range of motion, kyphotic angle, craniovertebral angle and proprioception. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Chronic Mechanical Neck Pain
- What is being tested?
- Group A:Thoracic thrust and Group B: Cervical non thrust mobilization
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 sitePakistan
- Study dates
- 25 Jan 2025to 15 Jan 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Both male and female
- Age: 20-40 years
- Numeric pain rating scale (3<) (13)
- Neck pain for more than 3 months
- Cervical hypomobility (C2-C7)
- Thoracic hypomobility (T1-T6)
- CranioVertebral Angle < 48 Degrees
Who cannot join
- Serious pathology (e.g. neoplasm, fracture)
- History of whiplash injury within the past 6 months
- Cervical spinal stenosis
- Radiculopathy
- Neurological deficit
- Structural deformities
Show all 9Show fewer
- Vertebrobasilar artery insufficiency
- Pregnancy
- Prior surgery of cervical or thoracic spine
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Foundation University College of Physical Therapy
Islamabad, Punjab Province, 46000
Ayesha Aslam, DPT, 03348648229, ayeshaaslam6@gmail.com
About this study
This study is a randomised controlled trial and the purpose of this study is to determine the effects of thoracic thrust with cervical non-thrust mobilization in mechanical neck pain on components such as pain, thoracic range of motion, kyphotic angle, craniovertebral angle and proprioception.
Read the detailed description
Particiapants will be divided into two groups through coin toss method, one group will recieve thoracic manipulation as addition to cervical mobilization and therapeutic exercises.
- Conditions
- Chronic Mechanical Neck Pain
- Being tested
- Group A:Thoracic thrust, Group B: Cervical non thrust mobilization
- Keywords
- neck pain, chronic neck pain, mechanical neck pain
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group A:Thoracic thrustProcedure or surgery
Group A will receive manipulation protocol as addition to standard treatment. Manipulation protocol:
High velocity, low amplitude as described by Maitland on thoracic hypomobile segments (T1-6)
Therapeutic exercise protocol:
Cervical and thoracic mobility exercises.
Group B: Cervical non thrust mobilizationProcedure or surgery
Intervention:
Group B will receive mobilization, post-facilitation stretch and exercise protocol.
Mobilization protocol:
Grade III or IV mobilization as described by Maitland on cervical Hypomobile segments (C2-7)
Therapeutic exercise protocol:
Cervical and thoracic mobility exercises.
| Study group | Role | What they receive |
|---|---|---|
| Group A; thoracic thrust | Experimental | thoracic thrust in addition to standard treatment Receives: Procedure: Group A:Thoracic thrust |
| Group B: cervical non-thrust mobilization | Active comparator | standard treatment of cervical non-thrust mobilization and home-based therapeutic exercises Receives: Procedure: Group B: Cervical non thrust mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity
Pain will be assessed by Numeric pain scale rating (NPRS).It is numeric 11-point scale, with 0 meaning no pain and 10 being worst pain.
Measured: baseline, 1st and 2nd week
Thoracic kyphosis
Thoracic Kyphosis is measured by Inclinometer. It is measured via summation of angles of two inclinometers, placed on anatomical landmarks (T1-3-12).
Measured: baseline, 1st week and 2nd week
Thoracic Range of Motion
Thoracic ROM (rotation) is measured by Inclinometer. Measured by placing the inclinometer at T1 segment with participant in a lumbar locked position.
Measured: baseline, 1st week, 2nd week
Craniovertebral angle
Craniovertebral angle (CVA)is measured by Goniometer. it is Angle measured between tragus of ear and C7 spinous process.
Measured: baseline,1st week, 2nd week
Proprioception
Proprioception is measured by Joint position sense/ error test. Participant wears a laser mounted headband and performs active neck movements with eyes closed on a target.
Measured: baseline, 1st and 2nd week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jan 2026
- Study start25 Jan 2025
- Primary completion30 Dec 2025 (estimated)
- Study completion15 Jan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Mechanical Neck PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 46 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07326696
- Sponsor's protocol ID
- FUI/CTR/2025/23
- Status last verified
- Dec 2025
- First submitted
- 26 Dec 2025
- Last updated
- 8 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Thoracic Thrust With Cervical Non-Thrust Mobilization in Mechanical Neck Pain
- ClinicalTrials.gov ID
- NCT07326696
- Acronym / sponsor ID
- FUI/CTR/2025/23
- Conditions
- Chronic Mechanical Neck Pain
- Keywords
- neck pain, chronic neck pain, mechanical neck pain
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 46 participants (estimated)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 25 Jan 2025 (actual)
- Primary completion
- 30 Dec 2025 (estimated)
- Study completion
- 15 Jan 2026 (estimated)
- First posted
- 8 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a randomised controlled trial and the purpose of this study is to determine the effects of thoracic thrust with cervical non-thrust mobilization in mechanical neck pain on components such as pain, thoracic range of motion, kyphotic angle, craniovertebral angle and proprioception.
Detailed description
Particiapants will be divided into two groups through coin toss method, one group will recieve thoracic manipulation as addition to cervical mobilization and therapeutic exercises.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A; thoracic thrust | Experimental | Procedure: Group A:Thoracic thrustthoracic thrust in addition to standard treatment |
| Group B: cervical non-thrust mobilization | Active comparator | Procedure: Group B: Cervical non thrust mobilizationstandard treatment of cervical non-thrust mobilization and home-based therapeutic exercises |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Both male and female
- Age: 20-40 years
- Numeric pain rating scale (3<) (13)
- Neck pain for more than 3 months
- Cervical hypomobility (C2-C7)
Key exclusion criteria (9 listed)
- Serious pathology (e.g. neoplasm, fracture)
- History of whiplash injury within the past 6 months
- Cervical spinal stenosis
- Radiculopathy
- Neurological deficit
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group A:Thoracic thrustGroup A will receive manipulation protocol as addition to standard treatment. Manipulation protocol: High velocity, low amplitude as described by Maitland on thoracic hypomobile segments (T1-6) Therapeutic exercise protocol: Cervical and thoracic mobility exercises. | Procedure or surgery | Group A; thoracic thrust |
| Group B: Cervical non thrust mobilizationIntervention: Group B will receive mobilization, post-facilitation stretch and exercise protocol. Mobilization protocol: Grade III or IV mobilization as described by Maitland on cervical Hypomobile segments (C2-7) Therapeutic exercise protocol: Cervical and thoracic mobility exercises. | Procedure or surgery | Group B: cervical non-thrust mobilization |
Primary outcome
Pain Intensity
Time frame: baseline, 1st and 2nd week
Pain will be assessed by Numeric pain scale rating (NPRS).It is numeric 11-point scale, with 0 meaning no pain and 10 being worst pain.
Thoracic kyphosis
Time frame: baseline, 1st week and 2nd week
Thoracic Kyphosis is measured by Inclinometer. It is measured via summation of angles of two inclinometers, placed on anatomical landmarks (T1-3-12).
Thoracic Range of Motion
Time frame: baseline, 1st week, 2nd week
Thoracic ROM (rotation) is measured by Inclinometer. Measured by placing the inclinometer at T1 segment with participant in a lumbar locked position.
Craniovertebral angle
Time frame: baseline,1st week, 2nd week
Craniovertebral angle (CVA)is measured by Goniometer. it is Angle measured between tragus of ear and C7 spinous process.
Proprioception
Time frame: baseline, 1st and 2nd week
Proprioception is measured by Joint position sense/ error test. Participant wears a laser mounted headband and performs active neck movements with eyes closed on a target.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group A:Thoracic thrust and Group B: Cervical non thrust mobilization in people with Chronic Mechanical Neck Pain, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 8 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ayesha Aslam (03348648229, ayeshaaslam6@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (time frame: baseline, 1st and 2nd week). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jan 2026; AzTrials last refreshed its copy on 26 Oct 2026.