Pulmonary AtelectasisLUNG USG SCORENCT07324122
Effect of Recruitment Maneuver on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Cholecystectomy
A study testing Alveolar recruitment manoeuvre and Lung-protective ventilation with lung ultrasound assessment in people with Pulmonary Atelectasis, run by Fatih Sultan Mehmet Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults undergoing elective laparoscopic cholecystectomy under general anaesthesia. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Pulmonary Atelectasis
- What is being tested?
- Alveolar recruitment manoeuvre and Lung-protective ventilation with lung ultrasound assessment
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 25 Apr 2025to 26 Oct 2025
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult patients scheduled for elective laparoscopic cholecystectomy under general anesthesia
- Age between 18 and 75 years
- Body mass index (BMI) < 30 kg/m²
- American Society of Anesthesiologists (ASA) physical status classification I-III
- Provision of written informed consent
Who cannot join
- Refusal to participate in the study
- Emergency surgical procedures
- Body mass index (BMI) ≥ 30 kg/m²
- American Society of Anesthesiologists (ASA) physical status classification IV
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul Provincial Health Directorate Fatih Sultan Mehmet Training and Research Hospital
Istanbul, Istanbul, 34000
About this study
Official title: EVALUATION OF THE EFFECT OF RECRUITMENT MANEUVER ON POSTOPERATIVE ATELECTASIS IN LAPAROSCOPIC CHOLECYSTECTOMY SURGERY USING LUS (LUG ULTRASOUND SCALE)
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults undergoing elective laparoscopic cholecystectomy under general anaesthesia. Eighty patients (ASA I-III) were allocated 1:1 to an RM group or a control group. Both groups received identical low-tidal-volume ventilation with 5 cmH₂O PEEP; the RM group additionally received a standardized stepwise recruitment manoeuvre at two points-after establishment of pneumoperitoneum and again before extubation-with PEEP returned to 5 cmH₂O after each manoeuvre. Lung aeration was assessed by an 8-zone lung ultrasound (LUS) protocol at five predefined perioperative time points. The primary outcome was the perioperative composite LUS score trajectory. Peripheral oxygen saturation, mean arterial pressure, and heart rate were assessed as safety outcomes.
Read the detailed description
Laparoscopic cholecystectomy under general anaesthesia with CO₂ pneumoperitoneum predictably reduces lung aeration and promotes atelectasis that global monitoring parameters may fail to detect. This trial compared two intraoperative ventilation strategies differing solely in the application of alveolar recruitment manoeuvres, using serial lung ultrasound to quantify regional aeration.
Adults aged 18-75 years, ASA physical status I-III, scheduled for elective laparoscopic cholecystectomy were eligible. Patients undergoing emergency surgery, with severe pre-existing pulmonary disease (e.g., COPD GOLD stage ≥ III, interstitial lung disease) or previous thoracic surgery, who were pregnant, or who required conversion to open surgery were excluded. Eligible participants were randomized 1:1 using a computer-generated sequence, with allocation concealed by sequentially numbered, sealed, opaque envelopes.
All patients received standardized general anaesthesia and volume-controlled ventilation (tidal volume 6-8 mL/kg predicted body weight, PEEP 5 cmH₂O, FiO₂ titrated to SpO₂ ≥ 95%, EtCO₂ 35-40 mmHg). In the RM group, a standardized stepwise recruitment manoeuvre (driving pressure 15 cmH₂O; PEEP incremented 5 → 10 → 15 cmH₂O in 10-15-second steps) was performed twice: first immediately after establishment of CO₂ pneumoperitoneum and surgical positioning, and second after pneumoperitoneum deflation and before extubation. PEEP was returned to 5 cmH₂O after each manoeuvre, identical to the control group, so that the groups differed only by the recruitment manoeuvres and not by sustained PEEP. The control group received no recruitment manoeuvre, with PEEP maintained at 5 cmH₂O throughout. Intra-abdominal pressure was limited to 12 mmHg.
An 8-zone LUS protocol (each hemithorax divided into anterior-upper, anterior-lower, lateral-upper, and lateral-lower regions) was applied at five predefined time points: T1, preoperative baseline; T2, 5 minutes after induction; T3, after pneumoperitoneum establishment and the first recruitment manoeuvre; T4, immediately after extubation and the second recruitment manoeuvre; and T5, 30 minutes after arrival in the post-anaesthesia care unit. LUS examinations were performed by a dedicated team of blinded anaesthesiology specialists independent of intraoperative ventilation management.
The primary outcome was the perioperative composite LUS score trajectory across the five time points, analysed with a linear mixed-effects model (group, time, and group × time interaction). Safety outcomes were peripheral oxygen saturation, mean arterial pressure, and heart rate at each time point.
- Conditions
- Pulmonary Atelectasis
- Being tested
- Alveolar recruitment manoeuvre, Lung-protective ventilation with lung ultrasound assessment
- Keywords
- Protective lung ventilation, Laparoscopic surgery, Alveolar recruitment, Pneumoperitoneum, Cholecystectomy, Perioperative respiratory complications, Lung ultrasound score, Lung ultrasound, LUS
- Medical subject headings
- Pulmonary Atelectasis, Pneumoperitoneum
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Alveolar recruitment manoeuvreProcedure or surgery
A standardized stepwise alveolar recruitment manoeuvre applied at two intraoperative time points: after establishment of CO₂ pneumoperitoneum and again before extubation. Each manoeuvre uses a fixed driving pressure of 15 cmH₂O with PEEP incremented stepwise (5 → 10 → 15 cmH₂O, 10-15 seconds per step), then PEEP returned to 5 cmH₂O. The manoeuvre is terminated if peak inspiratory pressure exceeds 35 cmH₂O or haemodynamic instability occurs. Applied in addition to low-tidal-volume protective ventilation.
Lung-protective ventilation with lung ultrasound assessmentProcedure or surgery
Volume-controlled low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP and FiO₂ titrated to maintain SpO₂ ≥ 95%, applied to both groups. Perioperative lung aeration is assessed using a standardized 8-zone lung ultrasound protocol at five predefined time points (preoperative baseline, 5 minutes post-induction, post-pneumoperitoneum, immediately post-extubation, and 30 minutes after PACU arrival) by blinded assessors independent of ventilation management.
| Study group | Role | What they receive |
|---|---|---|
| Recruitment manoeuvre (RM) group | Experimental | Patients receive low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP, plus a standardized stepwise alveolar recruitment manoeuvre applied at two time points: after establishment of CO₂ pneumoperitoneum and again before extubation. Each manoeuvre uses a fixed driving pressure of 15 cmH₂O with PEEP incremented stepwise (5 → 10 → 15 cmH₂O, 10-15 seconds per step); PEEP is returned to 5 cmH₂O after each manoeuvre. Lung aeration is assessed by 8-zone lung ultrasound at five predefined perioperative time points. Receives: Procedure: Alveolar recruitment manoeuvre |
| Control group (no recruitment manoeuvre) | Active comparator | Patients receive low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP maintained throughout the intraoperative period, without any alveolar recruitment manoeuvre. All other anaesthetic and surgical management is identical to the RM group. Lung aeration is assessed by 8-zone lung ultrasound at the same five predefined perioperative time points. Receives: Procedure: Lung-protective ventilation with lung ultrasound assessment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Lung Ultrasound Score (LUS)
Lung ultrasound score (LUS) assessed using a 8-zone scanning technique. Each zone is scored from 0 (normal aeration, A-lines) to 3 (lung consolidation). Total score ranges from 0 to 36, with higher scores indicating worse lung aeration. Change calculated as difference from baseline (T0) to T1 and T2.
Measured: Baseline (T0), 30 minutes after pneumoperitoneum (T1), and 30 minutes after desufflation (T2)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jan 2026
- Study start25 Apr 2025
- Primary completion25 Oct 2025
- Study completion26 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Pulmonary AtelectasisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two-arm parallel-group randomized controlled trial. Eligible patients were allocated 1:1 to a recruitment manoeuvre group or a control group using a computer-generated randomization sequence with allocation concealment by sequentially numbered, sealed, opaque envelopes. Both groups received identical low-tidal-volume ventilation with 5 cmH₂O PEEP; the groups differed only by the application of standardized alveolar recruitment manoeuvres in the intervention group.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- Fatih Sultan Mehmet Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- doga meric yukselen, MD, Study director, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITALelif acar deger, MD, Study chair, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITALoznur demiroluk, MD, Study chair, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITALarzu yildirim ar, MD, Study chair, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITALarsen gungor ay, MD, Study director, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITALcansu ofluoglu, MD, Principal investigator, ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07324122
- Sponsor's protocol ID
- FSMTRHLUS
- Other IDs
- 2025-KAEK-43
- Acronym
- LUNG USG SCORE
- Status last verified
- Jul 2026
- First submitted
- 24 Dec 2025
- Last updated
- 5 Aug 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared.
Publications
Liu Y, Wang J, Geng Y, Zhang Y, Su H, Yang Y. The effect of ultrasound-guided lung recruitment maneuvers on atelectasis in lung-healthy patients undergoing laparoscopic gynecologic surgery: a randomized controlled trial. BMC Anesthesiol. 2022 Jul 1;22(1):200. doi: 10.1186/s12871-022-01742-1.
PubMed 35778701Kim BR, Lee S, Bae H, Lee M, Bahk JH, Yoon S. Lung ultrasound score to determine the effect of fraction inspired oxygen during alveolar recruitment on absorption atelectasis in laparoscopic surgery: a randomized controlled trial. BMC Anesthesiol. 2020 Jul 18;20(1):173. doi: 10.1186/s12871-020-01090-y.
PubMed 32682397
Study at a glance
From the registry record, last updated by the sponsor on 5 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- EVALUATION OF THE EFFECT OF RECRUITMENT MANEUVER ON POSTOPERATIVE ATELECTASIS IN LAPAROSCOPIC CHOLECYSTECTOMY SURGERY USING LUS (LUG ULTRASOUND SCALE)
- ClinicalTrials.gov ID
- NCT07324122
- Acronym / sponsor ID
- LUNG USG SCORE / FSMTRHLUS
- Conditions
- Pulmonary Atelectasis
- Keywords
- Protective lung ventilation, Laparoscopic surgery, Alveolar recruitment, Pneumoperitoneum, Cholecystectomy, Perioperative respiratory complications, Lung ultrasound score, Lung ultrasound
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- Fatih Sultan Mehmet Training and Research HospitalUniversity, hospital or other
- Study start
- 25 Apr 2025 (actual)
- Primary completion
- 25 Oct 2025 (actual)
- Study completion
- 26 Oct 2025 (actual)
- First posted
- 7 Jan 2026 (actual)
- Results
- Posted 19 Feb 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults undergoing elective laparoscopic cholecystectomy under general anaesthesia. Eighty patients (ASA I-III) were allocated 1:1 to an RM group or a control group. Both groups received identical low-tidal-volume ventilation with 5 cmH₂O PEEP; the RM group additionally received a standardized stepwise recruitment manoeuvre at two points-after establishment of pneumoperitoneum and again before extubation-with PEEP returned to 5 cmH₂O after each manoeuvre. Lung aeration was assessed by an 8-zone lung ultrasound (LUS) protocol at five predefined perioperative time points. The primary outcome was the perioperative composite LUS score trajectory. Peripheral oxygen saturation, mean arterial pressure, and heart rate were assessed as safety outcomes.
Detailed description
Laparoscopic cholecystectomy under general anaesthesia with CO₂ pneumoperitoneum predictably reduces lung aeration and promotes atelectasis that global monitoring parameters may fail to detect. This trial compared two intraoperative ventilation strategies differing solely in the application of alveolar recruitment manoeuvres, using serial lung ultrasound to quantify regional aeration.
Adults aged 18-75 years, ASA physical status I-III, scheduled for elective laparoscopic cholecystectomy were eligible. Patients undergoing emergency surgery, with severe pre-existing pulmonary disease (e.g., COPD GOLD stage ≥ III, interstitial lung disease) or previous thoracic surgery, who were pregnant, or who required conversion to open surgery were excluded. Eligible participants were randomized 1:1 using a computer-generated sequence, with allocation concealed by sequentially numbered, sealed, opaque envelopes.
All patients received standardized general anaesthesia and volume-controlled ventilation (tidal volume 6-8 mL/kg predicted body weight, PEEP 5 cmH₂O, FiO₂ titrated to SpO₂ ≥ 95%, EtCO₂ 35-40 mmHg). In the RM group, a standardized stepwise recruitment manoeuvre (driving pressure 15 cmH₂O; PEEP incremented 5 → 10 → 15 cmH₂O in 10-15-second steps) was performed twice: first immediately after establishment of CO₂ pneumoperitoneum and surgical positioning, and second after pneumoperitoneum deflation and before extubation. PEEP was returned to 5 cmH₂O after each manoeuvre, identical to the control group, so that the groups differed only by the recruitment manoeuvres and not by sustained PEEP. The control group received no recruitment manoeuvre, with PEEP maintained at 5 cmH₂O throughout. Intra-abdominal pressure was limited to 12 mmHg.
An 8-zone LUS protocol (each hemithorax divided into anterior-upper, anterior-lower, lateral-upper, and lateral-lower regions) was applied at five predefined time points: T1, preoperative baseline; T2, 5 minutes after induction; T3, after pneumoperitoneum establishment and the first recruitment manoeuvre; T4, immediately after extubation and the second recruitment manoeuvre; and T5, 30 minutes after arrival in the post-anaesthesia care unit. LUS examinations were performed by a dedicated team of blinded anaesthesiology specialists independent of intraoperative ventilation management.
The primary outcome was the perioperative composite LUS score trajectory across the five time points, analysed with a linear mixed-effects model (group, time, and group × time interaction). Safety outcomes were peripheral oxygen saturation, mean arterial pressure, and heart rate at each time point.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Two-arm parallel-group randomized controlled trial. Eligible patients were allocated 1:1 to a recruitment manoeuvre group or a control group using a computer-generated randomization sequence with allocation concealment by sequentially numbered, sealed, opaque envelopes. Both groups received identical low-tidal-volume ventilation with 5 cmH₂O PEEP; the groups differed only by the application of standardized alveolar recruitment manoeuvres in the intervention group.
| Arm | Type | Receives |
|---|---|---|
| Recruitment manoeuvre (RM) group | Experimental | Procedure: Alveolar recruitment manoeuvrePatients receive low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP, plus a standardized stepwise alveolar recruitment manoeuvre applied at two time points: after establishment of CO₂ pneumoperitoneum and again before extubation. Each manoeuvre uses a fixed driving pressure of 15 cmH₂O with PEEP incremented stepwise (5 → 10 → 15 cmH₂O, 10-15 seconds per step); PEEP is returned to 5 cmH₂O after each manoeuvre. Lung aeration is assessed by 8-zone lung ultrasound at five predefined perioperative time points. |
| Control group (no recruitment manoeuvre) | Active comparator | Procedure: Lung-protective ventilation with lung ultrasound assessmentPatients receive low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP maintained throughout the intraoperative period, without any alveolar recruitment manoeuvre. All other anaesthetic and surgical management is identical to the RM group. Lung aeration is assessed by 8-zone lung ultrasound at the same five predefined perioperative time points. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Adult patients scheduled for elective laparoscopic cholecystectomy under general anesthesia
- Age between 18 and 75 years
- Body mass index (BMI) < 30 kg/m²
- American Society of Anesthesiologists (ASA) physical status classification I-III
- Provision of written informed consent
Key exclusion criteria (4 listed)
- Refusal to participate in the study
- Emergency surgical procedures
- Body mass index (BMI) ≥ 30 kg/m²
- American Society of Anesthesiologists (ASA) physical status classification IV
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Alveolar recruitment manoeuvreA standardized stepwise alveolar recruitment manoeuvre applied at two intraoperative time points: after establishment of CO₂ pneumoperitoneum and again before extubation. Each manoeuvre uses a fixed driving pressure of 15 cmH₂O with PEEP incremented stepwise (5 → 10 → 15 cmH₂O, 10-15 seconds per step), then PEEP returned to 5 cmH₂O. The manoeuvre is terminated if peak inspiratory pressure exceeds 35 cmH₂O or haemodynamic instability occurs. Applied in addition to low-tidal-volume protective ventilation. | Procedure or surgery | Recruitment manoeuvre (RM) group |
| Lung-protective ventilation with lung ultrasound assessmentVolume-controlled low-tidal-volume ventilation (6-8 mL/kg predicted body weight) with 5 cmH₂O PEEP and FiO₂ titrated to maintain SpO₂ ≥ 95%, applied to both groups. Perioperative lung aeration is assessed using a standardized 8-zone lung ultrasound protocol at five predefined time points (preoperative baseline, 5 minutes post-induction, post-pneumoperitoneum, immediately post-extubation, and 30 minutes after PACU arrival) by blinded assessors independent of ventilation management. | Procedure or surgery | Control group (no recruitment manoeuvre) |
Primary outcome
Change in Lung Ultrasound Score (LUS)
Time frame: Baseline (T0), 30 minutes after pneumoperitoneum (T1), and 30 minutes after desufflation (T2)
Lung ultrasound score (LUS) assessed using a 8-zone scanning technique. Each zone is scored from 0 (normal aeration, A-lines) to 3 (lung consolidation). Total score ranges from 0 to 36, with higher scores indicating worse lung aeration. Change calculated as difference from baseline (T0) to T1 and T2.
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Aug 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Results publication: PubMed 35778701Liu Y, Wang J, Geng Y, Zhang Y, Su H, Yang Y. The effect of ultrasound-guided lung recruitment maneuvers on atelectasis in lung-healthy patients undergoing laparoscopic gynecologic surgery: a randomized controlled trial. BMC Anesthesiol. 2022 Jul 1;22(1):200. doi: 10.1186/s12871-022-01742-1.
- Results publication: PubMed 32682397Kim BR, Lee S, Bae H, Lee M, Bahk JH, Yoon S. Lung ultrasound score to determine the effect of fraction inspired oxygen during alveolar recruitment on absorption atelectasis in laparoscopic surgery: a randomized controlled trial. BMC Anesthesiol. 2020 Jul 18;20(1):173. doi: 10.1186/s12871-020-01090-y.
- Individual participant dataSharing planned: No. Individual participant data will not be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
doga meric yukselen, MD study director
ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL
elif acar deger, MD study chair
ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL
oznur demiroluk, MD study chair
ISTANBUL PROVINCIAL HEALTH DIRECTORATE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Alveolar recruitment manoeuvre and Lung-protective ventilation with lung ultrasound assessment in people with Pulmonary Atelectasis, run by Fatih Sultan Mehmet Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 19 Feb 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Lung Ultrasound Score (LUS) (time frame: Baseline (T0), 30 minutes after pneumoperitoneum (T1), and 30 minutes after desufflation (T2)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07324122, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Aug 2026.