Stroke AssessmentNCT07318376
Effect of E-learning Training on National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) Assessment
A study testing Educational intervention in people with Stroke Assessment and National Institutes of Health Stroke Scale, run by Stuby Loric at 1 site in Switzerland.
Trial summary
The goal of this web-based randomized clinical trial is to evaluate whether an e-learning training program improves the accuracy of National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) assessments among practicing paramedics in French-speaking Switzerland who have not previously received… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke Assessment, National Institutes of Health Stroke Scale, Modified Rankin Scale
- What is being tested?
- Educational intervention
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteSwitzerland
- Study dates
- Apr 2026to Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Holding a paramedic title (recognized in Switzerland)
- Currently actively practicing in Switzerland
- Fluent in French (all study material will be provided in French)
Who cannot join
- Previously completed formal training on either the NIHSS or the mRS.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Laurent Suppan contact
Switzerland1 site
Genève TEAM Ambulances
Geneva, Canton of Geneva, 1201
Loric Stuby, +41228001212, l.stuby@gt-ambulances.ch
About this study
Official title: Effect of E-learning Training on National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) Assessment Performance: a Web-based Randomized Controlled Trial
The goal of this web-based randomized clinical trial is to evaluate whether an e-learning training program improves the accuracy of National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) assessments among practicing paramedics in French-speaking Switzerland who have not previously received formal training in these scales.
The main questions it aims to answer are:
Read more
- Does e-learning training improve performance on a standardized NIHSS assessment quiz compared with no prior training?
- Does e-learning training improve the accuracy of mRS assessment using case-based clinical vignettes compared with no prior training?
Researchers will compare paramedics who complete the NIHSS and mRS e-learning modules before assessment (intervention group) with paramedics who complete the assessments without prior training (control group) to determine whether e-learning training leads to higher assessment performance scores.
Participants will:
- Provide electronic informed consent via a secure web-based platform
- Be randomly assigned to either the intervention group or the control group
- Complete either the e-learning modules before assessment or the assessments before training, depending on group allocation
- Complete an online NIHSS quiz and mRS case-based vignettes
- Receive access to the NIHSS and mRS e-learning modules by the end of the study
- Conditions
- Stroke Assessment, National Institutes of Health Stroke Scale, Modified Rankin Scale, Clinical Competence, Education, Distance Learning-Online Learning
- Being tested
- Educational intervention
- Keywords
- E-learning, Web-based training, Stroke assessment, National Institutes of Health Stroke Scale (NIHSS), Modified Rankin Scale (mRS), Paramedics, Emergency Medical Services, Prehospital care, Clinical competence, Educational intervention, Randomized controlled trial, Performance assessment, Distance education, Continuing professional education
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Educational interventionOther
Educational intervention by the mean of an e-learning modules (NIHSS and mRS).
| Study group | Role | What they receive |
|---|---|---|
| Control group | No intervention | Control group: Participants will first complete the NIHSS quiz and mRS case vignettes without prior training. |
| Intervention group | Experimental | Participants will follow the e-learning modules (NIHSS and mRS). Receives: Other: Educational intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Performance on a NIHSS 50-item quiz
The primary outcome will be the performance on a NIHSS 50-item quiz consisting in 3 full assessments of a patient (3x15 items) plus 5 general questions (each question scores 1 point if correct, maximum total of 50 points).
Measured: From enrollment to the end of the study path in a timeframe of maximum 4 weeks.
Secondary outcomes (1)
Performance of mRS assessment
The secondary outcome will be the performance of mRS assessment of about 10 newly developed case-based vignettes (each question scores 1 point if correct, maximum total of 10 points).
Measured: From enrollment to the end of the study path in a timeframe of maximum 4 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Jan 2026
- Study startApr 2026 (estimated)
- Primary completionJul 2026 (estimated)
- Study completionJul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Stroke AssessmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stuby Loric
- Sponsor type
- University, hospital or other
- Collaborators
- University Hospital, Geneva, Geneve TEAM Ambulances
- Responsible party
- Sponsor-investigator, Stuby Loric, Geneve TEAM Ambulances
- Investigators
- Loric Stuby, Principal investigator, Genève TEAM Ambulances
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07318376
- Sponsor's protocol ID
- NIHSS-6
- Status last verified
- Jan 2026
- First submitted
- 23 Dec 2025
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Study data will be made available by deposition in a public repository (Yareta.org).
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of E-learning Training on National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) Assessment Performance: a Web-based Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07318376
- Acronym / sponsor ID
- NIHSS-6
- Conditions
- Stroke Assessment, National Institutes of Health Stroke Scale, Modified Rankin Scale, Clinical Competence, Education, Distance Learning-Online Learning
- Keywords
- E-learning, Web-based training, Stroke assessment, National Institutes of Health Stroke Scale (NIHSS), Modified Rankin Scale (mRS), Paramedics, Emergency Medical Services, Prehospital care
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Stuby LoricUniversity, hospital or other
- Collaborators
- University Hospital, Geneva, Geneve TEAM Ambulances
- Study start
- Apr 2026 (estimated)
- Primary completion
- Jul 2026 (estimated)
- Study completion
- Jul 2026 (estimated)
- First posted
- 6 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this web-based randomized clinical trial is to evaluate whether an e-learning training program improves the accuracy of National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) assessments among practicing paramedics in French-speaking Switzerland who have not previously received formal training in these scales.
The main questions it aims to answer are:
- Does e-learning training improve performance on a standardized NIHSS assessment quiz compared with no prior training?
- Does e-learning training improve the accuracy of mRS assessment using case-based clinical vignettes compared with no prior training?
Researchers will compare paramedics who complete the NIHSS and mRS e-learning modules before assessment (intervention group) with paramedics who complete the assessments without prior training (control group) to determine whether e-learning training leads to higher assessment performance scores.
Participants will:
- Provide electronic informed consent via a secure web-based platform
- Be randomly assigned to either the intervention group or the control group
- Complete either the e-learning modules before assessment or the assessments before training, depending on group allocation
- Complete an online NIHSS quiz and mRS case-based vignettes
- Receive access to the NIHSS and mRS e-learning modules by the end of the study
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control group | No intervention | –Control group: Participants will first complete the NIHSS quiz and mRS case vignettes without prior training. |
| Intervention group | Experimental | Other: Educational interventionParticipants will follow the e-learning modules (NIHSS and mRS). |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Holding a paramedic title (recognized in Switzerland)
- Currently actively practicing in Switzerland
- Fluent in French (all study material will be provided in French)
Key exclusion criteria (1 listed)
- Previously completed formal training on either the NIHSS or the mRS.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Educational interventionEducational intervention by the mean of an e-learning modules (NIHSS and mRS). | Other | Intervention group |
Primary outcome
Performance on a NIHSS 50-item quiz
Time frame: From enrollment to the end of the study path in a timeframe of maximum 4 weeks.
The primary outcome will be the performance on a NIHSS 50-item quiz consisting in 3 full assessments of a patient (3x15 items) plus 5 general questions (each question scores 1 point if correct, maximum total of 50 points).
1 secondary outcome
Performance of mRS assessment
Time frame: From enrollment to the end of the study path in a timeframe of maximum 4 weeks.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
- Individual participant dataSharing planned: Yes. Study data will be made available by deposition in a public repository (Yareta.org).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Laurent Suppan contact
Loric Stuby principal investigator
Genève TEAM Ambulances
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Educational intervention in people with Stroke Assessment and National Institutes of Health Stroke Scale, run by Stuby Loric at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Loric Stuby (+41228001212, l.stuby@gt-ambulances.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Performance on a NIHSS 50-item quiz (time frame: From enrollment to the end of the study path in a timeframe of maximum 4 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026.