Printed DenturesNCT07303530
Effect of Printing Layer Thickness on Growth of Candida Albicans in Completely Edentulous Patients Rehabilitated With 3D-Printed Maxillary Complete Denture Bases.
A study testing printing layer thickness of denture in people with Printed Dentures, run by Cairo University at 2 sites in Egypt.
Trial summary
In completely edentulous patients rehabilitated with 3D-printed maxillary dentures bases, does the printing layer thickness affect candidal adherence and growth on the fitting surface of dentures. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Printed Dentures
- What is being tested?
- printing layer thickness of denture
- Type of treatment
- Medical device
- How many people
- 10 participants
- Where
- 2 sitesEgypt
- Study dates
- 30 Jan 2026to 5 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Completely edentulous patients aged 30-80 years
- Oral cavity is free from any mucosal lesions.
- No systemic conditions that would contraindicate participation in the study.
Who cannot join
- History of allergic reactions to denture materials.
- Active mucosal lesions related to denture use.
- Pregnancy or lactation.
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt2 sites, 2 recruiting
- Recruiting
cairo University hospital
Cairo, Cairo Governorate
ahmed Abdelgawad mousa, MSc, +201553843228, ahmed_musa@dentistry.cu.edu.eg
ahmed musa, MSc, 01553843228, ahmed_musa@dentistry.cu.edu.eg
- Recruiting
faculty of dentistry Cairo hospital
Cairo, Cairo Governorate
ahmed Abdelgawad mousa, MSc, 00201553843228, ahmed_musa@dentistry.cu.edu.eg
ahmed musa, MSc, 01553843228, ahmed_musa@dentistry.cu.edu.eg
About this study
Official title: Effect of Printing Layer Thickness on Growth of Candida Albicans in Completely Edentulous Patients Rehabilitated With 3D-Printed Maxillary Complete Denture Bases: A Randomized Cross-over Study
In completely edentulous patients rehabilitated with 3D-printed maxillary dentures bases, does the printing layer thickness affect candidal adherence and growth on the fitting surface of dentures.
Read the detailed description
The trial will follow a cross-over design, where each participant will wear denture bases printed with three different layer thicknesses (25 µm, 50 µm, and 100 µm) at a random order. Each participant will wear each of the three dentures for an 8-week period, with a washout period of two weeks between each thickness.
- Conditions
- Printed Dentures
- Being tested
- printing layer thickness of denture
- Keywords
- Candida
- Medical subject headings
- Torulopsis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
printing layer thickness of dentureDevice
Also called other printing layer thickness
denture printed by multiple printing layer thicknesses to assess effect of layer thickness on fungal growth
What is being measured
The primary outcome is the main question the study is designed to answer.
Candidal growth
candidal growth over denture surface measured by colony-forming units (CFU)
Measured: 8-10 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Dec 2025
- Study start30 Jan 2026 (estimated)
- Primary completion5 Dec 2026 (estimated)
- Study completion5 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Printed DenturesStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Crossover
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 10 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, ahmed abdelgawad mousa, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07303530
- Sponsor's protocol ID
- 3354445
- Status last verified
- Dec 2025
- First submitted
- 25 Nov 2025
- Last updated
- 26 Dec 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Printing Layer Thickness on Growth of Candida Albicans in Completely Edentulous Patients Rehabilitated With 3D-Printed Maxillary Complete Denture Bases: A Randomized Cross-over Study
- ClinicalTrials.gov ID
- NCT07303530
- Acronym / sponsor ID
- 3354445
- Conditions
- Printed Dentures
- Keywords
- Candida
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 10 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 30 Jan 2026 (estimated)
- Primary completion
- 5 Dec 2026 (estimated)
- Study completion
- 5 Jan 2027 (estimated)
- First posted
- 26 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In completely edentulous patients rehabilitated with 3D-printed maxillary dentures bases, does the printing layer thickness affect candidal adherence and growth on the fitting surface of dentures.
Detailed description
The trial will follow a cross-over design, where each participant will wear denture bases printed with three different layer thicknesses (25 µm, 50 µm, and 100 µm) at a random order. Each participant will wear each of the three dentures for an 8-week period, with a washout period of two weeks between each thickness.
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Crossover
- Masking
- Triple blind (participant, investigator, outcomes assessor)
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (3 listed)
- Completely edentulous patients aged 30-80 years
- Oral cavity is free from any mucosal lesions.
- No systemic conditions that would contraindicate participation in the study.
Key exclusion criteria (3 listed)
- History of allergic reactions to denture materials.
- Active mucosal lesions related to denture use.
- Pregnancy or lactation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| printing layer thickness of dentureAlso: other printing layer thicknessdenture printed by multiple printing layer thicknesses to assess effect of layer thickness on fungal growth | Device | – |
Primary outcome
Candidal growth
Time frame: 8-10 weeks
candidal growth over denture surface measured by colony-forming units (CFU)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Dec 2025.
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Clinical Outcomes of 3D Printed and Milled Complete Dentures
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3D Metrology-Based Comparison of Functional Casts Made With Conventional and 3D-Printed Custom Trays
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Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial
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Not yet recruiting
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing printing layer thickness of denture in people with Printed Dentures, run by Cairo University at 2 sites in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Candidal growth (time frame: 8-10 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Dec 2025.