Atopic Dermatitis (AD)NCT07270965
Moisturization and Skin Hydration Study
A study testing Moisturizing while in shower/bath and Moisturizing after towel drying in people with Atopic Dermatitis (AD) and Atopic Dermatitis (Eczema), run by University of British Columbia at 1 site in Canada.
Trial summary
Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. Read more about this study
- Who is it for?
- Ages 12 to 18 years
- Conditions the study is for
- Atopic Dermatitis (AD), Atopic Dermatitis (Eczema)
- What is being tested?
- Moisturizing while in shower/bath and Moisturizing after towel drying
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteCanada
- Study dates
- Dec 2025to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Participants must have a diagnosis of atopic dermatitis/eczema.
- Participants must be between the age of 12-18.
- Participants must be able to bathe independently.
- Participants will be English speaking and able to complete questionnaires.
Who cannot join
- Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
- Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Understanding the Effect of Pre-Drying Moisturization on Skin Hydration
Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:
- Which moisturization technique is preferred: while showering/bathing or after towel drying?
- How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?
Read more
Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.
Participants will:
- Apply moisturizer while showering/bathing for one month and after towel drying for one month.
- Complete questionnaires on moisturization technique, skin feel, and itchiness.
- Undergo skin hydration measurements using a Corneometer® CM825 device.
- Conditions
- Atopic Dermatitis (AD), Atopic Dermatitis (Eczema)
- Being tested
- Moisturizing while in shower/bath, Moisturizing after towel drying
- Keywords
- Atopic Dermatitis, Eczema, AD, Moisturizer, Cream, Skin Hydration
- Medical subject headings
- Dermatitis, Atopic, Eczema
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Moisturizing while in shower/bathBehavioural
Applying moisturizer in the shower/bath.
Moisturizing after towel dryingBehavioural
Applying moisturizer out of the shower/bath after towel drying.
| Study group | Role | What they receive |
|---|---|---|
| Moisturizing while in shower/bath | Experimental | Not described Receives: Behavioral: Moisturizing while in shower/bath |
| Moisturizing after towel drying | Experimental | Not described Receives: Behavioral: Moisturizing after towel drying |
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of Participants Preferring Each Moisturization Technique
Participant reported preference of moisturization technique
Measured: Through study completion, an average of 2 months.
Secondary outcomes (1)
Skin Hydration Level
Skin electrical capacitance measured using Corneometer® CM825 as an indicator of skin hydration.
Measured: Through study completion, an average of 2 months.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Dec 2025
- Study startDec 2025 (estimated)
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Atopic Dermatitis (AD)Studies of the same condition, open and under way.
- More trials run by University of British ColumbiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of British Columbia
- Sponsor type
- University, hospital or other
- Collaborators
- L'Oreal
- Responsible party
- Principal investigator, Wingfield Rehmus, University of British Columbia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07270965
- Sponsor's protocol ID
- H25-02646
- Status last verified
- Nov 2025
- First submitted
- 21 Nov 2025
- Last updated
- 8 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared, but aggregated data from all participants will be shared.
Study at a glance
From the registry record, last updated by the sponsor on 8 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Understanding the Effect of Pre-Drying Moisturization on Skin Hydration
- ClinicalTrials.gov ID
- NCT07270965
- Acronym / sponsor ID
- H25-02646
- Conditions
- Atopic Dermatitis (AD), Atopic Dermatitis (Eczema)
- Keywords
- Atopic Dermatitis, Eczema, AD, Moisturizer, Cream, Skin Hydration
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- University of British ColumbiaUniversity, hospital or other
- Collaborators
- L'Oreal
- Study start
- Dec 2025 (estimated)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 8 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:
- Which moisturization technique is preferred: while showering/bathing or after towel drying?
- How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?
Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.
Participants will:
- Apply moisturizer while showering/bathing for one month and after towel drying for one month.
- Complete questionnaires on moisturization technique, skin feel, and itchiness.
- Undergo skin hydration measurements using a Corneometer® CM825 device.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Moisturizing while in shower/bath | Experimental | Behavioral: Moisturizing while in shower/bath |
| Moisturizing after towel drying | Experimental | Behavioral: Moisturizing after towel drying |
Who may qualify
- Ages
- 12 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (4 listed)
- Participants must have a diagnosis of atopic dermatitis/eczema.
- Participants must be between the age of 12-18.
- Participants must be able to bathe independently.
- Participants will be English speaking and able to complete questionnaires.
Key exclusion criteria (2 listed)
- Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
- Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Moisturizing while in shower/bathApplying moisturizer in the shower/bath. | Behavioural | Moisturizing while in shower/bath |
| Moisturizing after towel dryingApplying moisturizer out of the shower/bath after towel drying. | Behavioural | Moisturizing after towel drying |
Primary outcome
Proportion of Participants Preferring Each Moisturization Technique
Time frame: Through study completion, an average of 2 months.
Participant reported preference of moisturization technique
1 secondary outcome
Skin Hydration Level
Time frame: Through study completion, an average of 2 months.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Dec 2025.
- Individual participant dataSharing planned: No. Individual participant data will not be shared, but aggregated data from all participants will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Moisturizing while in shower/bath and Moisturizing after towel drying in people with Atopic Dermatitis (AD) and Atopic Dermatitis (Eczema), run by University of British Columbia at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Wingfield Rehmus, MD, MPH (1-604-875-2606, dermatologyresearch@cw.bc.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of Participants Preferring Each Moisturization Technique (time frame: Through study completion, an average of 2 months.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Dec 2025.