Smoking CessationIMPACTNCT07267936
Interventions for Maximizing Patient And Family Smoking Cessation Together
A study testing Household member support in people with Smoking Cessation, run by Papworth Hospital NHS Foundation Trust at 1 site in United Kingdom.
Trial summary
This feasibility study evaluates the effectiveness of a household-based smoking cessation intervention for patients and their household members. Patients who smoke and live with household members who also smoke will be invited to participate in the Treating Tobacco Dependency (TTD) program at Royal Papworth Hospital. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Smoking Cessation
- What is being tested?
- Household member support
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 231 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 7 Jul 2025to Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Any inpatient aged 18 and above admitted to Papworth Hospital who smoke. (Smoking is described as using any tobacco products as defined by the TTD programme)
- Patient and household members must be eligible to join the TTD programme.
- Patients must live in a household with other smokers.
- Participants must live in Cambridgeshire and/or be registered with a GP Practice in the Cambridgeshire \& Peterborough Integrated Care System
Who cannot join
- Pregnant individuals - Pregnant individuals who smoke are offered a differing pathway to the standard TTD programme.
- Contraindications for NRT.
- Any household member who smokes unwilling to participate.
- Individuals already enrolled on smoking cessation programme.
Trial locations and contacts
1 site in 1 country.
United Kingdom1 site
Royal Papworth Hospital NHS Foundation Trust
Cambridge, Cambridgeshire, CB2 0AY
About this study
This feasibility study evaluates the effectiveness of a household-based smoking cessation intervention for patients and their household members. Patients who smoke and live with household members who also smoke will be invited to participate in the Treating Tobacco Dependency (TTD) program at Royal Papworth Hospital. The study aims to assess whether providing support to both patients and their household members improves quit rates and reduces relapse risk.
Participants will receive nicotine replacement therapy (NRT) and behavioural support, with follow-up assessments at 28 days, 3 months, and 12 months after starting the program. This study will compare outcomes to historical data from patients who participated in the TTD program without household support.
Read the detailed description
The Treating Tobacco Dependency (TTD) program is currently available at Royal Papworth Hospital as part of an NHS initiative that started in August 2023. The program is available to all patients who smoke tobacco and are admitted to the hospital for at least 24 hours.
The TTD program provides NRT and behavioural counselling support, initially delivered by the TTD team at Royal Papworth Hospital, followed by HealthyYou, an NHS-approved stop smoking organization. Through this study, investigators are extending the invitation to household members of Royal Papworth Hospital patients to join the TTD program. This will allow the research team to assess whether a household-based intervention improves smoking cessation rates for both patients and their household members.
All participants will be followed up at 28 days, 3 months and 12 months post start of quit smoking. The smoking cessation rate will be compared to the routine TTD data set the research team has previously collected over the last year before household members were approached. This data will be acting as a control.
- Conditions
- Smoking Cessation
- Being tested
- Household member support
- Keywords
- Household-based intervention, Smoking Cessation, Tobacco dependency
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Household member supportOther
The intervention in this study involves inviting household members of the patients, to participate in the Treating Tobacco Dependency program.
| Study group | Role | What they receive |
|---|---|---|
| Patients with household members support | Experimental | Both the patients and the additional household members will be provided with Nicotine Replacement Therapy products and behavioural support. All participants will be followed up at 28 days, 3 months and 12 months post start Quit Date.
The intervention in this study involves inviting household members of the patients, to participate in the Treating Tobacco Dependency program.
The control group is patients without household members support. This is based on retrospective data of all patients who were admitted to Papworth Hospital and engaged with the Treating Tobacco Dependency Programme without any household members invited. Receives: Other: Household member support |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quit Rate among patients at 28 days
Assess difference in quit rates between patients with household support and the control group at 28 days.
Measured: 28 days
Secondary outcomes (4)
Patient relapse rate
Patient relapse rate at 3 and 12 months.
Measured: 3 and 12 months
Household member quit rate
Household member quit rate at 28 days, 3 months and 12 months.
Measured: 28 days, 3 months and 12 months
Difference in relapse rate between patients with and without household members support
Difference in relapse rates between the two groups at 3 months and 12 months (Patients supported with household members and the control group)
Measured: 3 months and 12 months
Acceptance rate of support among household members
Potential household members who were approached but did not agree to participate in the study will be analyzed for the Acceptance of Support Among Household Members Who Smoke (%) endpoint
Measured: Baseline (At the time of screening , prior to enrollment)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Dec 2025
- Study start7 Jul 2025
- Primary completion22 Apr 2026
- Study completionApr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Smoking CessationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- The intervention in this study involves inviting household members of the patients, to participate in the TTD program.
- Masking
- None (open label)
- Enrolment
- 231 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Papworth Hospital NHS Foundation Trust
- Sponsor type
- Other government
- Responsible party
- Sponsor
- Investigators
- Health Inequalities Specialist, Study chair, Papworth Hospital NHS Foundation Trust
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07267936
- Sponsor's protocol ID
- P03172
- Acronym
- IMPACT
- Status last verified
- May 2026
- First submitted
- 22 May 2025
- Last updated
- 14 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Interventions for Maximizing Patient And Family Smoking Cessation Together
- ClinicalTrials.gov ID
- NCT07267936
- Acronym / sponsor ID
- IMPACT / P03172
- Conditions
- Smoking Cessation
- Keywords
- Household-based intervention, Smoking Cessation, Tobacco dependency
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 231 participants (estimated)
- Lead sponsor
- Papworth Hospital NHS Foundation TrustOther government
- Study start
- 7 Jul 2025 (actual)
- Primary completion
- 22 Apr 2026 (actual)
- Study completion
- Apr 2027 (estimated)
- First posted
- 5 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This feasibility study evaluates the effectiveness of a household-based smoking cessation intervention for patients and their household members. Patients who smoke and live with household members who also smoke will be invited to participate in the Treating Tobacco Dependency (TTD) program at Royal Papworth Hospital. The study aims to assess whether providing support to both patients and their household members improves quit rates and reduces relapse risk.
Participants will receive nicotine replacement therapy (NRT) and behavioural support, with follow-up assessments at 28 days, 3 months, and 12 months after starting the program. This study will compare outcomes to historical data from patients who participated in the TTD program without household support.
Detailed description
The Treating Tobacco Dependency (TTD) program is currently available at Royal Papworth Hospital as part of an NHS initiative that started in August 2023. The program is available to all patients who smoke tobacco and are admitted to the hospital for at least 24 hours.
The TTD program provides NRT and behavioural counselling support, initially delivered by the TTD team at Royal Papworth Hospital, followed by HealthyYou, an NHS-approved stop smoking organization. Through this study, investigators are extending the invitation to household members of Royal Papworth Hospital patients to join the TTD program. This will allow the research team to assess whether a household-based intervention improves smoking cessation rates for both patients and their household members.
All participants will be followed up at 28 days, 3 months and 12 months post start of quit smoking. The smoking cessation rate will be compared to the routine TTD data set the research team has previously collected over the last year before household members were approached. This data will be acting as a control.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- The intervention in this study involves inviting household members of the patients, to participate in the TTD program.
| Arm | Type | Receives |
|---|---|---|
| Patients with household members support | Experimental | Other: Household member supportBoth the patients and the additional household members will be provided with Nicotine Replacement Therapy products and behavioural support. All participants will be followed up at 28 days, 3 months and 12 months post start Quit Date. The intervention in this study involves inviting household members of the patients, to participate in the Treating Tobacco Dependency program. The control group is patients without household members support. This is based on retrospective data of all patients who were admitted to Papworth Hospital and engaged with the Treating Tobacco Dependency Programme without any household members invited. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Any inpatient aged 18 and above admitted to Papworth Hospital who smoke. (Smoking is described as using any tobacco products as defined by the TTD programme)
- Patient and household members must be eligible to join the TTD programme.
- Patients must live in a household with other smokers.
- Participants must live in Cambridgeshire and/or be registered with a GP Practice in the Cambridgeshire \& Peterborough Integrated Care System
Key exclusion criteria (4 listed)
- Pregnant individuals - Pregnant individuals who smoke are offered a differing pathway to the standard TTD programme.
- Contraindications for NRT.
- Any household member who smokes unwilling to participate.
- Individuals already enrolled on smoking cessation programme.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Household member supportThe intervention in this study involves inviting household members of the patients, to participate in the Treating Tobacco Dependency program. | Other | Patients with household members support |
Primary outcome
Quit Rate among patients at 28 days
Time frame: 28 days
Assess difference in quit rates between patients with household support and the control group at 28 days.
4 secondary outcomes
Patient relapse rate
Time frame: 3 and 12 months
Household member quit rate
Time frame: 28 days, 3 months and 12 months
Difference in relapse rate between patients with and without household members support
Time frame: 3 months and 12 months
Acceptance rate of support among household members
Time frame: Baseline (At the time of screening , prior to enrollment)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Health Inequalities Specialist study chair
Papworth Hospital NHS Foundation Trust
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Household member support in people with Smoking Cessation, run by Papworth Hospital NHS Foundation Trust at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quit Rate among patients at 28 days (time frame: 28 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2026.