NO DECOMPENSATED ILLNESSNCT07264530
The Relationship of the Joint Blockage and Muscle Spasm
A study testing Mobilization technique for sacroiliac joint in people with NO DECOMPENSATED ILLNESS and Muscle Cramps, run by Charles University, Czech Republic at 1 site in Czechia.
Trial summary
An interventional study aimed at verifying the effect of sacroiliac joint blockage on changes in piriformis muscle tension. The study was conducted on 40 subjects, both male and female. Physical therapy methods were used to diagnose muscle tension as a diagnostic tool, along with a visual analogue scale. Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- NO DECOMPENSATED ILLNESS, Muscle Cramps, Joint Dysfunction
- What is being tested?
- Mobilization technique for sacroiliac joint
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteCzechia
- Study dates
- 10 Nov 2025to 10 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- palpation sensitivity of the piriformis muscle in the piriformis line,
- limited joint play of the sacroiliac joint,
- pain in the lower back, groin, perineum, buttocks, or hips, tenderness in the sacrum,
- pain or weakness during resisted abduction at 90° flexion in the hip joint,
- positive piriformis sign, positive Freiberg's test, positive Trendelenburg's test, or positive Pace's abduction test.
- At least 50% of the accompanying signs of sacroiliac joint blockage must be present in each subject.
Who cannot join
- acute (primarily infectious) diseases,
- persons in acute condition after an accident,
- persons recovering from an accident/illness
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Relationship Between the Blockage of the Sacroiliac Joint (SI) and the Spasm of the Piriformis Muscle.
An interventional study aimed at verifying the effect of sacroiliac joint blockage on changes in piriformis muscle tension. The study was conducted on 40 subjects, both male and female. Physical therapy methods were used to diagnose muscle tension as a diagnostic tool, along with a visual analogue scale. The intervention was performed using manual mobilisation techniques commonly used in clinical practice. The effectiveness was verified using the same physical therapy diagnostic tool as at the beginning. The entire research process is time-consuming, taking up to 1 hour per examinee.
Read the detailed description
Objectives: The main aim of this study is to summarise current knowledge about the relationship between functional joint blockage and chained muscle spasm. To verify the relationship between sacroiliac joint blockage and piriformis muscle using combined therapy as a diagnostic tool, where the main parameter monitored will be the intensity of piriformis muscle irritability before and after sacroiliac joint mobilisation.
Methods: Measurements will be taken on a group of 40 subjects. The research sample consists of people aged 18-60, randomly divided into an experimental and a control group. All subjects underwent an initial palpation examination of the piriformis muscle, during which the level of pain was determined on a numerical pain scale. All subjects then underwent measurement of the piriformis muscle's irritability threshold using the "Beauty-line device 4000 Topline" device. The experimental group then underwent therapeutic intervention in the form of sacroiliac joint mobilisation using the "Cluster of Lasslet" technique. This was followed by 30 minutes of relaxation. The control group received no therapeutic intervention and only 30 minutes of relaxation between the initial and final examinations. Both groups then underwent the same final examination as at the beginning.
The investigators expect a change in piriformis muscle hypertonicity after sacroiliac joint mobilisation, including a reduction in pain in this muscle, at a statistical significance level of 5%.
- Conditions
- NO DECOMPENSATED ILLNESS, Muscle Cramps, Joint Dysfunction
- Being tested
- Mobilization technique for sacroiliac joint
- Keywords
- joint blockage, muscle spasm, muscle irritability
- Medical subject headings
- Muscle Cramp, Joint Diseases, Spasm
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mobilization technique for sacroiliac jointProcedure or surgery
The subject lies on their stomach, mobilization maneuvers are performed, a total of 4 maneuvers according to the recommended "Cluster of Lasslet" procedure for the sacroiliac joint.
| Study group | Role | What they receive |
|---|---|---|
| Experimental investigated group | Experimental | Group to which the mobilization technique will be applied to the sacroiliac joint according to "Cluster of Lasslet" Receives: Procedure: Mobilization technique for sacroiliac joint |
| Control non-investigated group | No intervention | A control group that undergoes an initial examination but subsequently receives no therapy. After 30 minutes of quiet rest, it is examined again. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changing of piriformis muscle irritability
After removing the sacroiliac joint blockage, the irritability threshold of the piriformis muscle increases and its painfulness decreases. The reduction in pain will be evident based on instrumental measurements using the Beauty-line device and palpation examination.
Measured: one hour at all
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Dec 2025
- Study start10 Nov 2025
- Primary completion10 Nov 2025
- Study completion10 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for NO DECOMPENSATED ILLNESSStudies of the same condition, open and under way.
- More trials run by Charles University, Czech RepublicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- A group of suitable subjects (n=40) is divided into an experimental group and a control group (n=20). All subjects meet the study's inclusion criteria. All subjects undergo the same initial examination, including palpation of the piriformis muscle, joint play of the sacroiliac joint, and a visual analogue scale. The experimental group is treated with mobilisation techniques and left to rest for 30 minutes. The control group receives no mobilisation intervention and is only left to rest for 30 minutes. Subsequently, an exit examination identical to the entrance examination is performed. The results are entered into Excel tables and further processed using statistical methods.
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Charles University, Czech Republic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Malá Jitka, Charles University, Czech Republic
- Investigators
- Miroslav Petr, Doc., Study chair, Charles University, Faculty of physical education and sport
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07264530
- Sponsor's protocol ID
- Svobodova, Piriformis
- Status last verified
- Dec 2025
- First submitted
- 20 Nov 2025
- Last updated
- 4 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: not enough experience
Study at a glance
From the registry record, last updated by the sponsor on 4 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Relationship Between the Blockage of the Sacroiliac Joint (SI) and the Spasm of the Piriformis Muscle.
- ClinicalTrials.gov ID
- NCT07264530
- Acronym / sponsor ID
- Svobodova, Piriformis
- Conditions
- NO DECOMPENSATED ILLNESS, Muscle Cramps, Joint Dysfunction
- Keywords
- joint blockage, muscle spasm, muscle irritability
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Charles University, Czech RepublicUniversity, hospital or other
- Study start
- 10 Nov 2025 (actual)
- Primary completion
- 10 Nov 2025 (actual)
- Study completion
- 10 Nov 2025 (actual)
- First posted
- 4 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
An interventional study aimed at verifying the effect of sacroiliac joint blockage on changes in piriformis muscle tension. The study was conducted on 40 subjects, both male and female. Physical therapy methods were used to diagnose muscle tension as a diagnostic tool, along with a visual analogue scale. The intervention was performed using manual mobilisation techniques commonly used in clinical practice. The effectiveness was verified using the same physical therapy diagnostic tool as at the beginning. The entire research process is time-consuming, taking up to 1 hour per examinee.
Detailed description
Objectives: The main aim of this study is to summarise current knowledge about the relationship between functional joint blockage and chained muscle spasm. To verify the relationship between sacroiliac joint blockage and piriformis muscle using combined therapy as a diagnostic tool, where the main parameter monitored will be the intensity of piriformis muscle irritability before and after sacroiliac joint mobilisation.
Methods: Measurements will be taken on a group of 40 subjects. The research sample consists of people aged 18-60, randomly divided into an experimental and a control group. All subjects underwent an initial palpation examination of the piriformis muscle, during which the level of pain was determined on a numerical pain scale. All subjects then underwent measurement of the piriformis muscle's irritability threshold using the "Beauty-line device 4000 Topline" device. The experimental group then underwent therapeutic intervention in the form of sacroiliac joint mobilisation using the "Cluster of Lasslet" technique. This was followed by 30 minutes of relaxation. The control group received no therapeutic intervention and only 30 minutes of relaxation between the initial and final examinations. Both groups then underwent the same final examination as at the beginning.
The investigators expect a change in piriformis muscle hypertonicity after sacroiliac joint mobilisation, including a reduction in pain in this muscle, at a statistical significance level of 5%.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- A group of suitable subjects (n=40) is divided into an experimental group and a control group (n=20). All subjects meet the study's inclusion criteria. All subjects undergo the same initial examination, including palpation of the piriformis muscle, joint play of the sacroiliac joint, and a visual analogue scale. The experimental group is treated with mobilisation techniques and left to rest for 30 minutes. The control group receives no mobilisation intervention and is only left to rest for 30 minutes. Subsequently, an exit examination identical to the entrance examination is performed. The results are entered into Excel tables and further processed using statistical methods.
| Arm | Type | Receives |
|---|---|---|
| Experimental investigated group | Experimental | Procedure: Mobilization technique for sacroiliac jointGroup to which the mobilization technique will be applied to the sacroiliac joint according to "Cluster of Lasslet" |
| Control non-investigated group | No intervention | –A control group that undergoes an initial examination but subsequently receives no therapy. After 30 minutes of quiet rest, it is examined again. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- palpation sensitivity of the piriformis muscle in the piriformis line,
- limited joint play of the sacroiliac joint,
- pain in the lower back, groin, perineum, buttocks, or hips, tenderness in the sacrum,
- pain or weakness during resisted abduction at 90° flexion in the hip joint,
- positive piriformis sign, positive Freiberg's test, positive Trendelenburg's test, or positive Pace's abduction test.
Key exclusion criteria (3 listed)
- acute (primarily infectious) diseases,
- persons in acute condition after an accident,
- persons recovering from an accident/illness
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mobilization technique for sacroiliac jointThe subject lies on their stomach, mobilization maneuvers are performed, a total of 4 maneuvers according to the recommended "Cluster of Lasslet" procedure for the sacroiliac joint. | Procedure or surgery | Experimental investigated group |
Primary outcome
Changing of piriformis muscle irritability
Time frame: one hour at all
After removing the sacroiliac joint blockage, the irritability threshold of the piriformis muscle increases and its painfulness decreases. The reduction in pain will be evident based on instrumental measurements using the Beauty-line device and palpation examination.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Dec 2025.
- Individual participant dataSharing planned: No. not enough experience
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Miroslav Petr, Doc. study chair
Charles University, Faculty of physical education and sport
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mobilization technique for sacroiliac joint in people with NO DECOMPENSATED ILLNESS and Muscle Cramps, run by Charles University, Czech Republic at 1 site in Czechia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Czechia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changing of piriformis muscle irritability (time frame: one hour at all). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2025.