Brown CataractNCT07252154
Modified Nuclear Phacoemulsification in Brown Cataract
A study testing phacoemulsification in people with Brown Cataract, run by Assiut University at 1 site in Egypt.
Trial summary
Irrigation of the nucleus with saline for 30 seconds after creating the central groove. Read more about this study
- Who is it for?
- Ages 50 to 70 years
- Conditions the study is for
- Brown Cataract
- What is being tested?
- phacoemulsification
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Mar 2025to 1 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Brown cataract
Who cannot join
- white cataract
- soft cataract
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Modified Technique for Nuclear Phacoemulsification in Brown Cataractous Nucleus
Irrigation of the nucleus with saline for 30 seconds after creating the central groove.
Read the detailed description
The hard nucleus is physiologically immune against water flow from out to inside the nucleus but we discovered that it is not immune against the flow of water from inside the nucleus to outside. So, we are doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer.
. As we know, the nucleus of the lens has the highest concentration of crystalline (high osmotic pressure), so the water will flow from the center of the nucleus to the outer surface without any resistance, and all adhesions and bonds between lens fibers will be broken at once, and the nucleus becomes softer.
- Conditions
- Brown Cataract
- Being tested
- phacoemulsification
- Keywords
- phaco, hard nucleus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
phacoemulsificationProcedure or surgery
doing phacoemulsification as usual but we stop when the gutter becomes half the thickness of the nucleus then we use tip of the phaco as irrigation for 30 seconds. the nucleus will become more softer
| Study group | Role | What they receive |
|---|---|---|
| Brown cataract | Experimental | doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer Receives: Procedure: phacoemulsification |
What is being measured
The primary outcome is the main question the study is designed to answer.
phaco time
time of ultrasound power
Measured: 60 seconds
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Nov 2025
- Study start1 Mar 2025
- Primary completion1 Nov 2025
- Study completion1 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Brown CataractStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hassan Lotfy Fahmy, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07252154
- Sponsor's protocol ID
- 17209067
- Status last verified
- Nov 2025
- First submitted
- 19 Nov 2025
- Last updated
- 26 Nov 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Modified Technique for Nuclear Phacoemulsification in Brown Cataractous Nucleus
- ClinicalTrials.gov ID
- NCT07252154
- Acronym / sponsor ID
- 17209067
- Conditions
- Brown Cataract
- Keywords
- phaco, hard nucleus
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Mar 2025 (actual)
- Primary completion
- 1 Nov 2025 (actual)
- Study completion
- 1 Nov 2025 (actual)
- First posted
- 26 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Irrigation of the nucleus with saline for 30 seconds after creating the central groove.
Detailed description
The hard nucleus is physiologically immune against water flow from out to inside the nucleus but we discovered that it is not immune against the flow of water from inside the nucleus to outside. So, we are doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer.
. As we know, the nucleus of the lens has the highest concentration of crystalline (high osmotic pressure), so the water will flow from the center of the nucleus to the outer surface without any resistance, and all adhesions and bonds between lens fibers will be broken at once, and the nucleus becomes softer.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Brown cataract | Experimental | Procedure: phacoemulsificationdoing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer |
Who may qualify
- Ages
- 50 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Brown cataract
Key exclusion criteria (2 listed)
- white cataract
- soft cataract
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| phacoemulsificationdoing phacoemulsification as usual but we stop when the gutter becomes half the thickness of the nucleus then we use tip of the phaco as irrigation for 30 seconds. the nucleus will become more softer | Procedure or surgery | Brown cataract |
Primary outcome
phaco time
Time frame: 60 seconds
time of ultrasound power
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Nov 2025.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing phacoemulsification in people with Brown Cataract, run by Assiut University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
phaco time (time frame: 60 seconds). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Nov 2025.