Cerebral PalsyNCT07248566
Cognitive Sensory Motor Training Therapy for Children With Cerebral Palsy
A study testing Cognitive Sensory Motor Training Therapy and conventional occupational therapy in people with Cerebral Palsy, run by Riphah International University at 1 site in Pakistan.
Trial summary
The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Read more about this study
- Who is it for?
- Ages 6 to 12 years, women only
- Conditions the study is for
- Cerebral Palsy
- What is being tested?
- Cognitive Sensory Motor Training Therapy and conventional occupational therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 28 Oct 2025to 16 Jan 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 12 years
- Women only
- No healthy volunteers
- Child
Who may be able to join
- Children aged 6-12 years with cerebral palsy
- Diagnosis confirmed by pediatric neurologist or rehabilitation specialist
- Ability to follow simple instructions and participate in therapy sessions.
- Participants had to be able to focus attention on demonstrate level II and III on the Gross
- Motor Function Classification Scale (GMFCS)
- Level II or III on the Manual Ability Classification System (MACS)
Who cannot join
- Visual impairment or hearing defect
- Severe cognitive decline and aphasia
- Contractures that could limit the patient from maintaining the extended arm in a comfortable position,
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Muhammad Asif Jvaed
Lahore, Punjab Province, 54000
Muhammad asif Javed, MS-PT, 923224209422, a.javed@riphah.edu.pk
About this study
Official title: Effects of Cognitive Sensory Motor Training Therapy on Dexterity and Upper Limb Function in Children With Cerebral Palsy
The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal cord injury or deformity, diagnosis with other neurological conditions, and visual or hearing impairments will be excluded from the study.. The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.Outcome measures will include the dexterity, and upper limb function.Tools used for data collection will be Action Research Arm Test and Box and Block Test. Data analysis will utilize SPSS version 25.00.
Read the detailed description
Cerebral palsy defined as a neuro-impairment with motor disability caused by a non- progressive defect or lesion of the immature brain. Cerebral palsy (CP) impact approximately
1 in 500 children worldwide, affecting motor function, muscle tone, and coordination.
Children with CP will experience limitations in daily activities, social participation, and quality of life due to impaired upper limb function. To address this, rehabilitation strategies will focus on enhancing dexterity, and upper limb function. The aims of the study is to examine the effects of cognitive sensory motor training therapy on dexterity and upper limb function in children with CP. The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal cord injury or deformity, diagnosis with other neurological conditions, and visual or hearing impairments will be excluded from the study.. The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.Outcome measures will include the dexterity, and upper limb function.Tools used for data collection will be Action Research Arm Test and Box and Block Test. Data analysis will utilize SPSS version 25.00.
- Conditions
- Cerebral Palsy
- Being tested
- Cognitive Sensory Motor Training Therapy, conventional occupational therapy
- Keywords
- Cerebral palsy, Cognition, Functional activity, Dexterity
- Medical subject headings
- Cerebral Palsy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cognitive Sensory Motor Training TherapyOther
Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Cognitive exercise therapy combines spatial and tactile tasks to improve cognitive function, focusing on perception and sensory awareness.
Participants completed 5 tasks, customized to their recovery progress.
conventional occupational therapyOther
Participants received conventional occupational therapy, consisting of many purposeful kinetic activities such as skateboard-supported arm-sliding exercises on a tabletop, picking up a ball and putting it into a basket, bi-manual placing cone, shoulder curved arch, double curved arch, arm bicycling, donut on base, putty kneading, block stacking, peg board exercise, graded pinch exercise and plastic cone stacking. Therapists could offer passive, active-assistive or active training, as deemed appropriate to the patient's ability
| Study group | Role | What they receive |
|---|---|---|
| Group A | Active comparator | participated in Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Cognitive exercise therapy combines spatial and tactile tasks to improve cognitive function, focusing on perception and sensory awareness.
Participants completed 5 tasks, customized to their recovery progress Receives: Other: Cognitive Sensory Motor Training Therapy |
| Group B | Active comparator | participants received conventional occupational therapy, consisting of many purposeful kinetic activities such as skateboard-supported arm-sliding exercises on a tabletop, picking up a ball and putting it into a basket, bi-manual placing cone, shoulder curved arch, double curved arch, arm bicycling, donut on base, putty kneading, block stacking, peg board exercise, graded pinch exercise and plastic cone stacking. Therapists could offer passive, active-assistive or active training, as deemed appropriate to the patient's ability Receives: Other: conventional occupational therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Action Research Arm Test:
The ARAT is a standardized measure of the upper extremity (arm and hand) function based
on four movements
: grasping, grip-ping, pinching and gross movements of shoulder,elbow and fingers. ARAT has an ordinal 4-point scale (0-3) for 19 items. Scoring is determined as follows: 0, patient cannot perform any part of task;1, patient is able to lift the object completely from the platform; 2, function is performed fully but clumsily or with great difficulty; and 3, the movement is performed normally. The maximum score for each arm is 57 points.
Measured: The test can be completed in an average of 10 minutes but requires specific materials
Box and Block Test:
The box and block test 13 will be used to evaluate gross manual dexterity. The setup consists of two adjacent boxes of the same size (53.7 × 25.4 × 8.5cm), one of them filled with 150 blocks (2.5 cm 3).Between the two boxes, there is a partition 15.2 cm in height. The patient must move blocks one by one from one box to the other, over the partition.
Measured: The number moved in 60 seconds is the recorded score.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Nov 2025
- Study start28 Oct 2025
- Primary completion2 Jan 2026 (estimated)
- Study completion16 Jan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Cerebral PalsyStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal . The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Sadia Javed, MS-PT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07248566
- Sponsor's protocol ID
- REC/RCR&AHS/SADIAJAVED
- Status last verified
- Nov 2025
- First submitted
- 18 Nov 2025
- Last updated
- 25 Nov 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Choi W. Effects of Cognitive Exercise Therapy on Upper Extremity Sensorimotor Function and Activities of Daily Living in Patients with Chronic Stroke: A Randomized Controlled Trial. Healthcare (Basel). 2022 Feb 24;10(3):429. doi: 10.3390/healthcare10030429.
PubMed 35326907
Study at a glance
From the registry record, last updated by the sponsor on 25 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Cognitive Sensory Motor Training Therapy on Dexterity and Upper Limb Function in Children With Cerebral Palsy
- ClinicalTrials.gov ID
- NCT07248566
- Acronym / sponsor ID
- REC/RCR&AHS/SADIAJAVED
- Conditions
- Cerebral Palsy
- Keywords
- Cerebral palsy, Cognition, Functional activity, Dexterity
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 28 Oct 2025 (actual)
- Primary completion
- 2 Jan 2026 (estimated)
- Study completion
- 16 Jan 2026 (estimated)
- First posted
- 25 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal cord injury or deformity, diagnosis with other neurological conditions, and visual or hearing impairments will be excluded from the study.. The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.Outcome measures will include the dexterity, and upper limb function.Tools used for data collection will be Action Research Arm Test and Box and Block Test. Data analysis will utilize SPSS version 25.00.
Detailed description
Cerebral palsy defined as a neuro-impairment with motor disability caused by a non- progressive defect or lesion of the immature brain. Cerebral palsy (CP) impact approximately
1 in 500 children worldwide, affecting motor function, muscle tone, and coordination.
Children with CP will experience limitations in daily activities, social participation, and quality of life due to impaired upper limb function. To address this, rehabilitation strategies will focus on enhancing dexterity, and upper limb function. The aims of the study is to examine the effects of cognitive sensory motor training therapy on dexterity and upper limb function in children with CP. The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal cord injury or deformity, diagnosis with other neurological conditions, and visual or hearing impairments will be excluded from the study.. The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.Outcome measures will include the dexterity, and upper limb function.Tools used for data collection will be Action Research Arm Test and Box and Block Test. Data analysis will utilize SPSS version 25.00.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated. Inclusion criteria for this study will be consist of diagnosis with cerebral palsy, age 6-12, ability to participate in cognitive sensory motor training therapy, stable medical condition, and informed consent from parents/guardians. Participants with severe cognitive impairments, unstable medical condition, history of spinal . The Experimental group will receive Cognitive Sensory Motor Training Therapy and Routine Physical Therapy, while the Control group will receive Routine Physical Therapy.Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Data collection will be done before and after the interventions.
| Arm | Type | Receives |
|---|---|---|
| Group A | Active comparator | Other: Cognitive Sensory Motor Training Therapyparticipated in Cognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Cognitive exercise therapy combines spatial and tactile tasks to improve cognitive function, focusing on perception and sensory awareness. Participants completed 5 tasks, customized to their recovery progress |
| Group B | Active comparator | Other: conventional occupational therapyparticipants received conventional occupational therapy, consisting of many purposeful kinetic activities such as skateboard-supported arm-sliding exercises on a tabletop, picking up a ball and putting it into a basket, bi-manual placing cone, shoulder curved arch, double curved arch, arm bicycling, donut on base, putty kneading, block stacking, peg board exercise, graded pinch exercise and plastic cone stacking. Therapists could offer passive, active-assistive or active training, as deemed appropriate to the patient's ability |
Who may qualify
- Ages
- 6 to 12 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (6 listed)
- Children aged 6-12 years with cerebral palsy
- Diagnosis confirmed by pediatric neurologist or rehabilitation specialist
- Ability to follow simple instructions and participate in therapy sessions.
- Participants had to be able to focus attention on demonstrate level II and III on the Gross
- Motor Function Classification Scale (GMFCS)
Key exclusion criteria (3 listed)
- Visual impairment or hearing defect
- Severe cognitive decline and aphasia
- Contractures that could limit the patient from maintaining the extended arm in a comfortable position,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cognitive Sensory Motor Training TherapyCognitive Sensory Motor Training Therapy (CSMT) for 35 minutes, five times a week, over 12 weeks. Cognitive exercise therapy combines spatial and tactile tasks to improve cognitive function, focusing on perception and sensory awareness. Participants completed 5 tasks, customized to their recovery progress. | Other | Group A |
| conventional occupational therapyParticipants received conventional occupational therapy, consisting of many purposeful kinetic activities such as skateboard-supported arm-sliding exercises on a tabletop, picking up a ball and putting it into a basket, bi-manual placing cone, shoulder curved arch, double curved arch, arm bicycling, donut on base, putty kneading, block stacking, peg board exercise, graded pinch exercise and plastic cone stacking. Therapists could offer passive, active-assistive or active training, as deemed appropriate to the patient's ability | Other | Group B |
Primary outcome
Action Research Arm Test:
Time frame: The test can be completed in an average of 10 minutes but requires specific materials
The ARAT is a standardized measure of the upper extremity (arm and hand) function based on four movements : grasping, grip-ping, pinching and gross movements of shoulder,elbow and fingers. ARAT has an ordinal 4-point scale (0-3) for 19 items. Scoring is determined as follows: 0, patient cannot perform any part of task;1, patient is able to lift the object completely from the platform; 2, function is performed fully but clumsily or with great difficulty; and 3, the movement is performed normally. The maximum score for each arm is 57 points.
Box and Block Test:
Time frame: The number moved in 60 seconds is the recorded score.
The box and block test 13 will be used to evaluate gross manual dexterity. The setup consists of two adjacent boxes of the same size (53.7 × 25.4 × 8.5cm), one of them filled with 150 blocks (2.5 cm 3).Between the two boxes, there is a partition 15.2 cm in height. The patient must move blocks one by one from one box to the other, over the partition.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Nov 2025.
- Background: PubMed 35326907Choi W. Effects of Cognitive Exercise Therapy on Upper Extremity Sensorimotor Function and Activities of Daily Living in Patients with Chronic Stroke: A Randomized Controlled Trial. Healthcare (Basel). 2022 Feb 24;10(3):429. doi: 10.3390/healthcare10030429.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sadia Javed, MS-PT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cognitive Sensory Motor Training Therapy and conventional occupational therapy in people with Cerebral Palsy, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Imran Amjad, PHD (9233224390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Action Research Arm Test: (time frame: The test can be completed in an average of 10 minutes but requires specific materials). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07248566, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Nov 2025.