Neglect, SensoryNeglex01NCT07227844
Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation
A study testing VR Neglect Training in people with Neglect, Sensory and Neglect, Hemispatial, run by Markey Olson at 1 site in United States.
Trial summary
Neglect, a common and disabling neurological deficit post-CNS injury, profoundly hinders recovery and escalates healthcare costs. Current diagnostic tools are often insensitive or impractical, and while therapies exist, a significant research gap remains. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Neglect, Sensory, Neglect, Hemispatial, Neglect, Hemisensory
- What is being tested?
- VR Neglect Training
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5 participants
- Where
- 1 siteUnited States
- Study dates
- 31 Dec 2025to 31 Dec 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- The study will involve patients over the age of 18 who have been diagnosed with a neurological injury that includes: ischemic stroke, hemorrhagic stroke, tumor, or trauma.
- Neurological injury that localizes to only one side of the brain
- At least one hand that retains dexterity enough to use a controller to extinguish the visual stimulus.
- Cognitive ability to understand simple instructions on how to use the device
- Visual fields intact
Who cannot join
- Bilateral symptomatic injury
- Inability to consent or to comply with study
- Blindness or severe visual deficits other than neglect
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Barrow Neurological Institute
Phoenix, Arizona, 85013
Markey Olson, PhD, 602-406-5944, neuromodulationresearch@commonspirit.org
About this study
Official title: Pilot Study of a Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation
Neglect, a common and disabling neurological deficit post-CNS injury, profoundly hinders recovery and escalates healthcare costs. Current diagnostic tools are often insensitive or impractical, and while therapies exist, a significant research gap remains. Traditional methods, including standardized scales and paper-pencil tests, lack precision; even advanced video oculography is limited by cost and accessibility. Rehabilitative approaches like visual scanning and prism adaptation offer some benefit, but more effective solutions are needed. This project utilizes a non-invasive neuromodulatory training approach via a mixed-reality visual attention task delivered through a virtual reality headset. This system aims to improve both neglect diagnosis and personalized therapeutic intervention. The study will assess the headset's safety and practicality, its capacity to detect and lateralize neglect, and its long-term effect on improving attention to the neglected field. By measuring reaction times to visual stimuli within the VR environment, the research seeks to develop a more accessible and impactful tool for both assessing and treating neglect, potentially enabling self-directed therapy and enhancing patient outcomes.
- Conditions
- Neglect, Sensory, Neglect, Hemispatial, Neglect, Hemisensory
- Being tested
- VR Neglect Training
- Keywords
- neglect
- Medical subject headings
- Perceptual Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
VR Neglect TrainingDevice
VR Neglect Training
| Study group | Role | What they receive |
|---|---|---|
| Treatment | Experimental | Not described Receives: Device: VR Neglect Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Improvement in Neglect
Measured as improvement in percentage of lines detected at each location in the VR app
Measured: 6 months
Secondary outcomes (2)
Feasibility/Usage, sessions
Number of sessions completed by each participant
Measured: 6 months
Feasibility/Usage, time
Total time spent using the device
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Nov 2025
- Study start31 Dec 2025 (estimated)
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neglect, SensoryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 5 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Markey Olson
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Markey Olson, St. Joseph's Hospital and Medical Center, Phoenix
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07227844
- Sponsor's protocol ID
- 26-500-131-30-06
- Acronym
- Neglex01
- Status last verified
- Nov 2025
- First submitted
- 7 Nov 2025
- Last updated
- 13 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- Undecided