Thoracic KyphosisNCT07218614
Can Mobilizations Applied to the Thoracic Spine Improve Oxygen Saturation Levels and Thoracic Kyphosis in E-Cigarette Smokers?
A study testing Thoracic Mobilization and Light Touch Contact in people with Thoracic Kyphosis, run by New York Institute of Technology at 1 site in United States.
Trial summary
The goal of this study is to determine if manual therapy can improve thoracic spinal posture and pulse oximetery in individuals who use e-cigarettes. The main questions the study aims to answer are: Is there an immediate improvements in thoracic posture Is there immediate improvements in pulse oximetery Research will… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Thoracic Kyphosis
- What is being tested?
- Thoracic Mobilization and Light Touch Contact
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 20 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Oct 2025to 15 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Current e-cigarette user Accentuated thoracic kyphosis (Cobb angle >20 degrees) Age range: at least 18 years old Good overall health
Who cannot join
- History of respiratory disease Recent vertebral fractures Recent spinal surgery Vertebral instability Congenital or acquired thoracic cage deformities Prolonged steroid use Osteoporosis/osteoporosis Inability to provide informed consent
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
NYIT
Old Westbury, New York, 11568
Teresa M Ingenito, DPT, 516-635-3974, tingenit@nyit.edu
Mark J Gugliotti, DPT, 631-512-5559, mgugliot@nyit.edu
About this study
The goal of this study is to determine if manual therapy can improve thoracic spinal posture and pulse oximetery in individuals who use e-cigarettes.
The main questions the study aims to answer are:
- Is there an immediate improvements in thoracic posture
- Is there immediate improvements in pulse oximetery Research will compare an experimental group and a control group to examine the effects.
Read the detailed description
All participants will be recruited from flyers posted throughout the NYIT Long Island campus. The participants will be screened for inclusion using set criteria by the PI.
In this crossover design study, participants will be randomly assigned to either an intervention experimental group or sham control group. The intervention group will received a thoracic extension mobilization to the mid-thoracic spine for a duration of 60 seconds and this will be repeated for a total of three times. The sham group will received a light, non-therapeutic touch to both scapulae which will be applied for three minutes. Both interventions will be performed in a seated position. Measurements of thoracic kyphosis and oxygen saturation will be taken before and after each procedure using inclinometers and a pulse oximeter, respectively.
After a washout period of one week, the participants will be return and receive the other form of intervention that they did no receive in in the first week. All procedures and outcomes will be performed as noted above.
- Conditions
- Thoracic Kyphosis
- Being tested
- Thoracic Mobilization, Light Touch Contact
- Keywords
- Thoracic spine, pulse oximetery, mobilzation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Thoracic MobilizationOther
The intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position.
Light Touch ContactOther
The sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position.
| Study group | Role | What they receive |
|---|---|---|
| Thoracic Mobilization | Experimental | The intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position. Receives: Other: Thoracic Mobilization |
| Light Touch Contact | Sham comparator | The sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position. Receives: Other: Light Touch Contact |
What is being measured
The primary outcome is the main question the study is designed to answer.
Angle of Thoracic Kyphosis
Measurement of the thoracic kyphosis will be made both pre and post treatment using excepted normative values (Cobb angle)
Measured: Immediately before and after each intervention
Secondary outcomes (1)
Oxygen Saturation
Percentage of oxygen found in the peripheral circulation using a pulse oximeter
Measured: immediately before and after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Oct 2025
- Study start15 Oct 2025 (estimated)
- Primary completion1 Apr 2026 (estimated)
- Study completion15 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thoracic KyphosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Experimental group will serve as their own control after a one-week washout period.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- New York Institute of Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Teresa M Ingenito, DPT, Principal investigator, New York Institute of Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07218614
- Sponsor's protocol ID
- NYIT-IRB-2025-299
- Status last verified
- May 2025
- First submitted
- 16 Oct 2025
- Last updated
- 20 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share IPD for this study.
Study at a glance
From the registry record, last updated by the sponsor on 20 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Can Mobilizations Applied to the Thoracic Spine Improve Oxygen Saturation Levels and Thoracic Kyphosis in E-Cigarette Smokers?
- ClinicalTrials.gov ID
- NCT07218614
- Acronym / sponsor ID
- NYIT-IRB-2025-299
- Conditions
- Thoracic Kyphosis
- Keywords
- Thoracic spine, pulse oximetery, mobilzation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- New York Institute of TechnologyUniversity, hospital or other
- Study start
- 15 Oct 2025 (estimated)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 15 May 2026 (estimated)
- First posted
- 20 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to determine if manual therapy can improve thoracic spinal posture and pulse oximetery in individuals who use e-cigarettes.
The main questions the study aims to answer are:
- Is there an immediate improvements in thoracic posture
- Is there immediate improvements in pulse oximetery Research will compare an experimental group and a control group to examine the effects.
Detailed description
All participants will be recruited from flyers posted throughout the NYIT Long Island campus. The participants will be screened for inclusion using set criteria by the PI.
In this crossover design study, participants will be randomly assigned to either an intervention experimental group or sham control group. The intervention group will received a thoracic extension mobilization to the mid-thoracic spine for a duration of 60 seconds and this will be repeated for a total of three times. The sham group will received a light, non-therapeutic touch to both scapulae which will be applied for three minutes. Both interventions will be performed in a seated position. Measurements of thoracic kyphosis and oxygen saturation will be taken before and after each procedure using inclinometers and a pulse oximeter, respectively.
After a washout period of one week, the participants will be return and receive the other form of intervention that they did no receive in in the first week. All procedures and outcomes will be performed as noted above.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Experimental group will serve as their own control after a one-week washout period.
| Arm | Type | Receives |
|---|---|---|
| Thoracic Mobilization | Experimental | Other: Thoracic MobilizationThe intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position. |
| Light Touch Contact | Sham comparator | Other: Light Touch ContactThe sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Current e-cigarette user Accentuated thoracic kyphosis (Cobb angle >20 degrees) Age range: at least 18 years old Good overall health
Key exclusion criteria (1 listed)
- History of respiratory disease Recent vertebral fractures Recent spinal surgery Vertebral instability Congenital or acquired thoracic cage deformities Prolonged steroid use Osteoporosis/osteoporosis Inability to provide informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Thoracic MobilizationThe intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position. | Other | Thoracic Mobilization |
| Light Touch ContactThe sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position. | Other | Light Touch Contact |
Primary outcome
Angle of Thoracic Kyphosis
Time frame: Immediately before and after each intervention
Measurement of the thoracic kyphosis will be made both pre and post treatment using excepted normative values (Cobb angle)
1 secondary outcome
Oxygen Saturation
Time frame: immediately before and after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Oct 2025.
- Individual participant dataSharing planned: No. There is no plan to share IPD for this study.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Teresa M Ingenito, DPT principal investigator
New York Institute of Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Thoracic Mobilization and Light Touch Contact in people with Thoracic Kyphosis, run by New York Institute of Technology at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Teresa M Ingenito, DPT (516-635-3974, tingenit@nyit.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Angle of Thoracic Kyphosis (time frame: Immediately before and after each intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Oct 2025.