Deviated Nasal Septum and Maxillary SinusitisNCT07210827
Deviated Nasal Septum Effect on Maxillary Sinus Volumes and Development of Maxillary Sinusitis by CT
An observational study of Deviated Nasal Septum and Maxillary Sinusitis, run by Assiut University.
Trial summary
By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of… Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Deviated Nasal Septum and Maxillary Sinusitis
- How many people
- 120 participants
- Where
- No sites listed yet
- Study dates
- 1 Oct 2025to Oct 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Adult, Older adult
Study population: Patients presented to outpatient clinic at Assiut University hospital complaining of nasal symptoms like nasal obstruction, rhinorrhea ,headache, and recurrent sinusitis.
Who may be able to join
- Age ≥18 years.
- Availability of high-resolution CT scans of paranasal Sinuses (axial, coronal, sagittal views).
- Adequate imaging quality allowing sinus volumetry and septal deviation measurement.
- Anatomical landmarks visible: Crista galli, hard palate, choanae, uncinate process/OMC region clearly identifiable to permit NSD measurement and sinus segmentation.
Who cannot join
- Age < 18 years.
- Previous sinonasal or maxillofacial surgery.
- History of facial trauma or fractures affecting the nasal septum or sinus walls.
- Sinonasal tumors, polyps, or large cysts.
- Congenital craniofacial anomalies (e.g., cleft palate).
- head and neck syndromes.
- Cases with systemic diseases affecting growth and development.
- -
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effect of Nasal Septal Deviation on Maxillary Sinus Volumes and Development of Maxillary Sinusitis :A CT Study.
By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of the contralateral side.
- Medical subject headings
- Maxillary Sinusitis
What is being measured
The primary outcome is the main question the study is designed to answer.
CT based comparison in cases with deviated nasal septum
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2025
- Study start1 Oct 2025 (estimated)
- Primary completionOct 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Deviated Nasal Septum and Maxillary SinusitisStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rana Emad Ali, Assiut University
- Investigators
- Ahmed Abdelaleem, Study chair, Professor at ENT department,Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07210827
- Sponsor's protocol ID
- CT in nasal septal deviation
- Status last verified
- Sep 2025
- First submitted
- 30 Sep 2025
- Last updated
- 7 Oct 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Razavi M, Shams N, Pirasteh SMA. Determining the effects of deviated nasal septum on maxillary sinus volume using cone-beam computed tomography. Immunopathol Persa. 2023;9(1):e34427
Elahi MM, Frenkiel S, Fageeh N. Paraseptal structural changes and chronic sinus disease in relation to the deviated septum. J Otolaryngol. 1997 Aug;26(4):236-40.
PubMed 9263892Serifoglu I, Oz II, Damar M, Buyukuysal MC, Tosun A, Tokgoz O. Relationship between the degree and direction of nasal septum deviation and nasal bone morphology. Head Face Med. 2017 Feb 28;13(1):3. doi: 10.1186/s13005-017-0136-2.
PubMed 28245851
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Nasal Septal Deviation on Maxillary Sinus Volumes and Development of Maxillary Sinusitis :A CT Study.
- ClinicalTrials.gov ID
- NCT07210827
- Acronym / sponsor ID
- CT in nasal septal deviation
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Oct 2025 (estimated)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Oct 2026 (estimated)
- First posted
- 7 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of the contralateral side.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Patients presented to outpatient clinic at Assiut University hospital complaining of nasal symptoms like nasal obstruction, rhinorrhea ,headache, and recurrent sinusitis.
Key inclusion criteria (4 listed)
- Age ≥18 years.
- Availability of high-resolution CT scans of paranasal Sinuses (axial, coronal, sagittal views).
- Adequate imaging quality allowing sinus volumetry and septal deviation measurement.
- Anatomical landmarks visible: Crista galli, hard palate, choanae, uncinate process/OMC region clearly identifiable to permit NSD measurement and sinus segmentation.
Key exclusion criteria (8 listed)
- Age < 18 years.
- Previous sinonasal or maxillofacial surgery.
- History of facial trauma or fractures affecting the nasal septum or sinus walls.
- Sinonasal tumors, polyps, or large cysts.
- Congenital craniofacial anomalies (e.g., cleft palate).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
CT based comparison in cases with deviated nasal septum
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2025.
- Results publicationRazavi M, Shams N, Pirasteh SMA. Determining the effects of deviated nasal septum on maxillary sinus volume using cone-beam computed tomography. Immunopathol Persa. 2023;9(1):e34427
- Results publication: PubMed 9263892Elahi MM, Frenkiel S, Fageeh N. Paraseptal structural changes and chronic sinus disease in relation to the deviated septum. J Otolaryngol. 1997 Aug;26(4):236-40.
- Results publication: PubMed 28245851Serifoglu I, Oz II, Damar M, Buyukuysal MC, Tosun A, Tokgoz O. Relationship between the degree and direction of nasal septum deviation and nasal bone morphology. Head Face Med. 2017 Feb 28;13(1):3. doi: 10.1186/s13005-017-0136-2.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ahmed Abdelaleem study chair
Professor at ENT department,Assiut University
Questions about this trial
What is this clinical trial studying?
An observational study of Deviated Nasal Septum and Maxillary Sinusitis, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Rana Emad Ali (20+1026232442, Rana.17289805@med.aun.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
CT based comparison in cases with deviated nasal septum (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07210827, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2025; AzTrials last refreshed its copy on 30 Oct 2026.