Anterior Cruciate Ligament TearIMAGERIEMOTRNCT07210489
Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery
A study testing Reconstructive surgery after anterior cruciate ligament rupture and sessions from a physical therapist in people with Anterior Cruciate Ligament Tear, run by GCS Ramsay Santé pour l'Enseignement et la Recherche at 1 site in France.
Trial summary
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months post-surgery versus patients who did not receive the motor imagery program. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Anterior Cruciate Ligament Tear
- What is being tested?
- Reconstructive surgery after anterior cruciate ligament rupture and sessions from a physical therapist
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteFrance
- Study dates
- Oct 2026to Mar 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients aged 18 to 45;
- Individuals who have undergone anterior cruciate ligament reconstruction for the first time on the operated leg;
- Patients able to understand and read French;
- Affiliation with a social insurance plan;
- Signed informed consent.
Who cannot join
- Recurrence or rupture of the contralateral anterior cruciate ligament;
- History of another orthopedic surgery on the ipsilateral and/or contralateral lower limb;
- History of an injury to the ipsilateral and/or contralateral lower limb within the last 3 months;
- Osteotomy;
- Cognitive disorders observed by the investigator for inclusion ;
- Vestibular disorders known to the patient or observed by the investigator for inclusion;
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- Post-surgical complications (infection, early graft rupture);
- Patient participating in another interventional clinical trial, or in a period of exclusion from another interventional study;
- Patient under guardianship or conservatorship;
- Pregnant or breastfeeding women.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site
Clinique de la Sauvegarde
Lyon, 69009
Benoit PAIROT DE FONTENAY, benoit.pdf@gmx.com
About this study
Official title: Therapeutic Benefits of a Motor Imaging Protocol After Anterior Cruciate Ligament Reconstruction Surgery: Study of Lower Limb Symmetry During Various Functional Tests
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months post-surgery versus patients who did not receive the motor imagery program.
Read the detailed description
This is a prospective, comparative, randomized, controlled, single-blind (patient), single-center study evaluating the effects of a motor imagery program in parallel with rehabilitation sessions in patients who have had an anterior cruciate ligament rupture.
The study population is composed of adult patients who underwent reconstructive surgery after anterior cruciate ligament rupture, followed up at the Clinique de la Sauvegarde in Lyon for post-operative functional and strength testing of the anterior cruciate ligament.
Patients included in the study will be randomized into two study arms (experimental arm and control arm).
- Conditions
- Anterior Cruciate Ligament Tear
- Being tested
- Reconstructive surgery after anterior cruciate ligament rupture, sessions from a physical therapist
- Medical subject headings
- Anterior Cruciate Ligament Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Reconstructive surgery after anterior cruciate ligament ruptureProcedure or surgery
surgical technique for repairing the cruciate ligament
sessions from a physical therapistOther
sessions from a physical therapist in accordance with standard practice
| Study group | Role | What they receive |
|---|---|---|
| Motor imagery program | Experimental | Patients will receive rehabilitation sessions from a physical therapist in accordance with standard practice and will be asked to complete a 3-week motor imagery program starting 3 months after anterior cruciate ligament surgery. Receives: Procedure: Reconstructive surgery after anterior cruciate ligament rupture; Other: sessions from a physical therapist |
| Cognitive (non-motor) task program | Active comparator | Patients will receive rehabilitation sessions from a physical therapist in accordance with standard practice and will be asked to complete a 3-week cognitive (non-motor) task program starting 3 months after anterior cruciate ligament surgery. Receives: Procedure: Reconstructive surgery after anterior cruciate ligament rupture; Other: sessions from a physical therapist |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evolution of limb symmetry
Evolution of limb symmetry assessed by the Limb Symmetry Index in %
Measured: between 3 and 4.5 months
Isometric quadriceps strength
Isometric quadriceps strength using a Micro Fet handheld dynamometer (in Newtons)
Measured: between 3 and 4.5 months
Isometric hamstring strength
Isometric hamstring strength measured using a Micro Fet handheld dynamometer (in Newtons)
Measured: between 3 and 4.5 months
Average concentric strength
Average concentric strength during a counter-movement jump measured using a force platform (in Newtons)
Measured: between 3 and 4.5 months
Average strength
Average strength during a squat measured using a force platform (in Newtons)
Measured: between 3 and 4.5 months
Quadriceps activation measured
Quadriceps activation measured using electromyography
Measured: between 3 and 4.5 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2025
- Study startOct 2026 (estimated)
- Primary completionMar 2028 (estimated)
- Study completionMar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Cruciate Ligament TearStudies of the same condition, open and under way.
- More trials run by GCS Ramsay Santé pour l'Enseignement et la RechercheThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Prospective, comparative, randomized, controlled, single-blind (patient), single-center study
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 70 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- Euraxi Pharma
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07210489
- Sponsor's protocol ID
- 2025-A01415-44
- Acronym
- IMAGERIEMOTR
- Status last verified
- Sep 2026
- First submitted
- 19 Sep 2025
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Therapeutic Benefits of a Motor Imaging Protocol After Anterior Cruciate Ligament Reconstruction Surgery: Study of Lower Limb Symmetry During Various Functional Tests
- ClinicalTrials.gov ID
- NCT07210489
- Acronym / sponsor ID
- IMAGERIEMOTR / 2025-A01415-44
- Conditions
- Anterior Cruciate Ligament Tear
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- GCS Ramsay Santé pour l'Enseignement et la RechercheUniversity, hospital or other
- Collaborators
- Euraxi Pharma
- Study start
- Oct 2026 (estimated)
- Primary completion
- Mar 2028 (estimated)
- Study completion
- Mar 2028 (estimated)
- First posted
- 7 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months post-surgery versus patients who did not receive the motor imagery program.
Detailed description
This is a prospective, comparative, randomized, controlled, single-blind (patient), single-center study evaluating the effects of a motor imagery program in parallel with rehabilitation sessions in patients who have had an anterior cruciate ligament rupture.
The study population is composed of adult patients who underwent reconstructive surgery after anterior cruciate ligament rupture, followed up at the Clinique de la Sauvegarde in Lyon for post-operative functional and strength testing of the anterior cruciate ligament.
Patients included in the study will be randomized into two study arms (experimental arm and control arm).
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Prospective, comparative, randomized, controlled, single-blind (patient), single-center study
| Arm | Type | Receives |
|---|---|---|
| Motor imagery program | Experimental | Procedure: Reconstructive surgery after anterior cruciate ligament rupture, Other: sessions from a physical therapistPatients will receive rehabilitation sessions from a physical therapist in accordance with standard practice and will be asked to complete a 3-week motor imagery program starting 3 months after anterior cruciate ligament surgery. |
| Cognitive (non-motor) task program | Active comparator | Procedure: Reconstructive surgery after anterior cruciate ligament rupture, Other: sessions from a physical therapistPatients will receive rehabilitation sessions from a physical therapist in accordance with standard practice and will be asked to complete a 3-week cognitive (non-motor) task program starting 3 months after anterior cruciate ligament surgery. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Patients aged 18 to 45;
- Individuals who have undergone anterior cruciate ligament reconstruction for the first time on the operated leg;
- Patients able to understand and read French;
- Affiliation with a social insurance plan;
- Signed informed consent.
Key exclusion criteria (10 listed)
- Recurrence or rupture of the contralateral anterior cruciate ligament;
- History of another orthopedic surgery on the ipsilateral and/or contralateral lower limb;
- History of an injury to the ipsilateral and/or contralateral lower limb within the last 3 months;
- Osteotomy;
- Cognitive disorders observed by the investigator for inclusion ;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Reconstructive surgery after anterior cruciate ligament rupturesurgical technique for repairing the cruciate ligament | Procedure or surgery | Cognitive (non-motor) task program, Motor imagery program |
| sessions from a physical therapistsessions from a physical therapist in accordance with standard practice | Other | Cognitive (non-motor) task program, Motor imagery program |
Primary outcome
Evolution of limb symmetry
Time frame: between 3 and 4.5 months
Evolution of limb symmetry assessed by the Limb Symmetry Index in %
Isometric quadriceps strength
Time frame: between 3 and 4.5 months
Isometric quadriceps strength using a Micro Fet handheld dynamometer (in Newtons)
Isometric hamstring strength
Time frame: between 3 and 4.5 months
Isometric hamstring strength measured using a Micro Fet handheld dynamometer (in Newtons)
Average concentric strength
Time frame: between 3 and 4.5 months
Average concentric strength during a counter-movement jump measured using a force platform (in Newtons)
Average strength
Time frame: between 3 and 4.5 months
Average strength during a squat measured using a force platform (in Newtons)
Quadriceps activation measured
Time frame: between 3 and 4.5 months
Quadriceps activation measured using electromyography
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Reconstructive surgery after anterior cruciate ligament rupture and sessions from a physical therapist in people with Anterior Cruciate Ligament Tear, run by GCS Ramsay Santé pour l'Enseignement et la Recherche at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Benoit PAIROT DE FONTENAY (601740875 ext. +33, benoit.pdf@gmx.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evolution of limb symmetry (time frame: between 3 and 4.5 months). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.