NeurocysticercosisNCT07208656
The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis
A study testing Medical TV Drama Episode (House M.D.) in people with Neurocysticercosis and Health Literacy, run by Cephas Health Research Initiative Inc, Ibadan, Nigeria.
Trial summary
This randomized controlled trial evaluates whether exposure to a medical television drama improves knowledge of neurocysticercosis (NCC) among young adults. Sixty participants aged 18-35 will be randomly assigned to either an intervention group, which will watch a medically relevant TV episode (House M.D., Season 1… Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Neurocysticercosis, Health Literacy, Epilepsy
- What is being tested?
- Medical TV Drama Episode (House M.D.)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- 15 Dec 2025to 15 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Aged 18 to 35 years
- Proficient in English (reading and comprehension)
- Has access to a stable internet connection
- Possesses a screen-enabled device (e.g., smartphone, tablet, or computer)
- Has access to the Netflix streaming platform
Who cannot join
- Has formal education in medical or health sciences
- Has a prior diagnosis of neurocysticercosis (NCC)
- Has previously participated in any NCC-related health literacy or awareness program
- Lacks access to the Netflix movie platform
- Below 18 years or above 35 years of age
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis: An Online Open-Label Two-Arm Randomized Controlled Trial
This randomized controlled trial evaluates whether exposure to a medical television drama improves knowledge of neurocysticercosis (NCC) among young adults. Sixty participants aged 18-35 will be randomly assigned to either an intervention group, which will watch a medically relevant TV episode (House M.D., Season 1, Episode 1), or a control group with no media exposure. Both groups will complete pre- and post-test questionnaires assessing knowledge of NCC. The primary outcome is change in NCC-related knowledge. Secondary outcomes include motivation to seek further health information and perceived credibility of the media source
Read the detailed description
Neurocysticercosis (NCC) is a parasitic infection of the central nervous system caused by the larval stage of Taenia solium, the pork tapeworm. It is one of the leading preventable causes of epilepsy worldwide, particularly in low- and middle-income countries (LMICs). Despite this, awareness and understanding of NCC remain low among young adults, who often play a key role in disseminating health information within their families and communities. Conventional health education efforts have had limited success in increasing public literacy about NCC, underscoring the need for innovative, engaging communication strategies.
This study uses an open-label, two-arm randomized controlled trial design to evaluate whether exposure to a medical television drama can improve knowledge of NCC among young adults. The trial will be conducted entirely online to enable participation from a geographically diverse population and to reflect modern media consumption patterns. After providing electronic informed consent, eligible participants will be randomly assigned to either an intervention or control group in a 1:1 ratio using a computer-generated allocation process to ensure randomization integrity.
Participants in the intervention group will watch House M.D., Season 1, Episode 1 - a medically themed television episode featuring a dramatized case of parasitic brain infection with conceptual relevance to NCC. The control group will not view the episode during the study period but will be offered access to the same content after data collection is complete. Both groups will complete structured online questionnaires before and after the intervention period to measure changes in NCC-related knowledge and attitudes. These questionnaires have been developed and validated through expert review and pilot testing.
The trial's primary objective is to determine whether viewing the medical TV drama improves knowledge of NCC, as measured by changes in pre- and post-intervention knowledge scores. Secondary objectives include assessing participants' motivation to learn more about NCC and their perception of the credibility of the TV drama as an educational resource. Statistical analyses will include paired and independent t-tests (or corresponding non-parametric tests where appropriate), with significance set at p < 0.05.
Data will be collected securely using encrypted online survey platforms. All responses will be anonymized, and no personally identifiable information will be stored. Data access will be limited to the research team, and all procedures will comply with international data protection standards.
This trial is designed in accordance with the CONSORT guidelines for randomized behavioral and educational interventions. Ethical approval has been obtained from the Research Ethics Committee of Caleb University, Nigeria, and the study will adhere to the principles outlined in the Declaration of Helsinki (1964). Participation is voluntary, and participants may withdraw at any time before data analysis without consequence.
This research is innovative in its use of entertainment-education as a vehicle for improving disease literacy. By evaluating the effect of a medical TV drama on public knowledge of NCC, the study aims to provide evidence for scalable, cost-effective, and culturally adaptable strategies for health communication in resource-limited settings. The findings are expected to contribute to global public health education efforts, particularly those addressing neglected parasitic diseases and preventable causes of epilepsy.
- Conditions
- Neurocysticercosis, Health Literacy, Epilepsy
- Being tested
- Medical TV Drama Episode (House M.D.)
- Medical subject headings
- Neurocysticercosis, Epilepsy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Medical TV Drama Episode (House M.D.)Behavioural
Also called House M.D. Season 1, Episode 1
Participants in the experimental group will watch a selected episode of the medical drama House M.D. (Season 1, Episode 1), which includes a dramatized storyline relevant to neurocysticercosis. The episode is intended to deliver narrative-based health education. After viewing, participants will complete post-test questionnaires assessing changes in knowledge, motivation, and credibility compared to pre-test results.
| Study group | Role | What they receive |
|---|---|---|
| Intervention (House M.D. Episode) | Experimental | Participants in this arm will watch a selected episode of the medical television drama House M.D. (Season 1, Episode 1), which features a dramatized case of neurocysticercosis. The intervention is designed to provide narrative-based exposure to information relevant to the disease. Participants will complete pre- and post-intervention questionnaires assessing knowledge, motivation, and credibility. Receives: Behavioral: Medical TV Drama Episode (House M.D.) |
| Control (No Episode) | No intervention | Participants in this arm will not receive any exposure to medical television content during the study period. They will complete the same pre- and post-intervention questionnaires as the intervention group, allowing comparison of changes in knowledge, motivation, and credibility. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Neurocysticercosis (NCC) Knowledge Score
Knowledge of neurocysticercosis (NCC) will be assessed using the Neurocysticercosis Knowledge Questionnaire, a 10-item multiple-choice instrument developed for this study. Each correct answer is scored as 1 point, and each incorrect or "I don't know" response is scored as 0 points. The total score represents the sum of correct answers, with a minimum possible score of 0 and a maximum possible score of 10. Higher scores indicate better knowledge of NCC across domains such as cause, transmission, symptoms, prevention, and treatment. The primary outcome is the change in total knowledge score from baseline (pre-test) to immediately post-intervention, compared between the intervention and control groups
Measured: Baseline and immediately post-intervention (within 1 hour)
Secondary outcomes (3)
Retention of Neurocysticercosis Knowledge
Knowledge retention will be assessed using the Neurocysticercosis Knowledge Questionnaire, the same 10-item multiple-choice instrument used at baseline and immediately post-intervention. Each correct answer is scored as 1 point, and incorrect or "I don't know" responses are scored as 0 points. The total score is the sum of correct responses, with a minimum possible score of 0 and a maximum possible score of 10. Higher scores indicate better retention of NCC knowledge.
The outcome measure is the change in total knowledge score from baseline (pre-test) to 4 weeks post-intervention, as well as between-group differences in retained knowledge over time.
Measured: 4 weeks post-intervention.
Perceived Credibility of the Medical TV Drama
Perceived credibility of the medical TV drama as a health information source will be measured using the Perceived Credibility of Health Media Scale, a 5-item Likert-type scale adapted for this study. Each item is rated from 1 ("Strongly Disagree") to 5 ("Strongly Agree"), assessing dimensions such as trustworthiness, accuracy, and believability of the episode's medical content. Scores for all items will be summed to produce a total credibility score, with a minimum possible score of 5 and a maximum possible score of 25. Higher scores indicate greater perceived credibility and trust in the medical TV drama as a reliable health education resource.
The outcome measure is the mean total credibility score immediately following the intervention, compared between the intervention and control groups.
Measured: Immediately post-intervention (within 1 hour).
Motivation to Seek Further Health Information
Participants' motivation to seek additional information about neurocysticercosis (NCC) will be assessed using the Motivation to Seek Health Information Scale, a single-item 5-point Likert-type measure adapted for this study. Participants will rate their likelihood of looking for more information about NCC following the intervention, with response options ranging from 1 ("Not at all likely") to 5 ("Extremely likely"). Scores range from 1 to 5, where higher scores indicate greater motivation to seek additional health information.
The outcome will be reported as the mean motivation score immediately post-intervention and compared between the intervention and control groups.
Measured: Immediately post-intervention (within 1 hour).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Oct 2025
- Study start15 Dec 2025 (estimated)
- Primary completion15 Feb 2026 (estimated)
- Study completion15 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for NeurocysticercosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two-arm, open-label, randomized controlled trial with parallel assignment.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cephas Health Research Initiative Inc, Ibadan, Nigeria
- Sponsor type
- Research network
- Responsible party
- Principal investigator, Emeka Okeke, Cephas Health Research Initiative Inc, Ibadan, Nigeria
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07208656
- Sponsor's protocol ID
- CUL25/NCC/001
- Status last verified
- Nov 2025
- First submitted
- 28 Sep 2025
- Last updated
- 4 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared.
Study at a glance
From the registry record, last updated by the sponsor on 4 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis: An Online Open-Label Two-Arm Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07208656
- Acronym / sponsor ID
- CUL25/NCC/001
- Conditions
- Neurocysticercosis, Health Literacy, Epilepsy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Cephas Health Research Initiative Inc, Ibadan, NigeriaResearch network
- Study start
- 15 Dec 2025 (estimated)
- Primary completion
- 15 Feb 2026 (estimated)
- Study completion
- 15 Apr 2026 (estimated)
- First posted
- 6 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial evaluates whether exposure to a medical television drama improves knowledge of neurocysticercosis (NCC) among young adults. Sixty participants aged 18-35 will be randomly assigned to either an intervention group, which will watch a medically relevant TV episode (House M.D., Season 1, Episode 1), or a control group with no media exposure. Both groups will complete pre- and post-test questionnaires assessing knowledge of NCC. The primary outcome is change in NCC-related knowledge. Secondary outcomes include motivation to seek further health information and perceived credibility of the media source
Detailed description
Neurocysticercosis (NCC) is a parasitic infection of the central nervous system caused by the larval stage of Taenia solium, the pork tapeworm. It is one of the leading preventable causes of epilepsy worldwide, particularly in low- and middle-income countries (LMICs). Despite this, awareness and understanding of NCC remain low among young adults, who often play a key role in disseminating health information within their families and communities. Conventional health education efforts have had limited success in increasing public literacy about NCC, underscoring the need for innovative, engaging communication strategies.
This study uses an open-label, two-arm randomized controlled trial design to evaluate whether exposure to a medical television drama can improve knowledge of NCC among young adults. The trial will be conducted entirely online to enable participation from a geographically diverse population and to reflect modern media consumption patterns. After providing electronic informed consent, eligible participants will be randomly assigned to either an intervention or control group in a 1:1 ratio using a computer-generated allocation process to ensure randomization integrity.
Participants in the intervention group will watch House M.D., Season 1, Episode 1 - a medically themed television episode featuring a dramatized case of parasitic brain infection with conceptual relevance to NCC. The control group will not view the episode during the study period but will be offered access to the same content after data collection is complete. Both groups will complete structured online questionnaires before and after the intervention period to measure changes in NCC-related knowledge and attitudes. These questionnaires have been developed and validated through expert review and pilot testing.
The trial's primary objective is to determine whether viewing the medical TV drama improves knowledge of NCC, as measured by changes in pre- and post-intervention knowledge scores. Secondary objectives include assessing participants' motivation to learn more about NCC and their perception of the credibility of the TV drama as an educational resource. Statistical analyses will include paired and independent t-tests (or corresponding non-parametric tests where appropriate), with significance set at p < 0.05.
Data will be collected securely using encrypted online survey platforms. All responses will be anonymized, and no personally identifiable information will be stored. Data access will be limited to the research team, and all procedures will comply with international data protection standards.
This trial is designed in accordance with the CONSORT guidelines for randomized behavioral and educational interventions. Ethical approval has been obtained from the Research Ethics Committee of Caleb University, Nigeria, and the study will adhere to the principles outlined in the Declaration of Helsinki (1964). Participation is voluntary, and participants may withdraw at any time before data analysis without consequence.
This research is innovative in its use of entertainment-education as a vehicle for improving disease literacy. By evaluating the effect of a medical TV drama on public knowledge of NCC, the study aims to provide evidence for scalable, cost-effective, and culturally adaptable strategies for health communication in resource-limited settings. The findings are expected to contribute to global public health education efforts, particularly those addressing neglected parasitic diseases and preventable causes of epilepsy.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Two-arm, open-label, randomized controlled trial with parallel assignment.
| Arm | Type | Receives |
|---|---|---|
| Intervention (House M.D. Episode) | Experimental | Behavioral: Medical TV Drama Episode (House M.D.)Participants in this arm will watch a selected episode of the medical television drama House M.D. (Season 1, Episode 1), which features a dramatized case of neurocysticercosis. The intervention is designed to provide narrative-based exposure to information relevant to the disease. Participants will complete pre- and post-intervention questionnaires assessing knowledge, motivation, and credibility. |
| Control (No Episode) | No intervention | –Participants in this arm will not receive any exposure to medical television content during the study period. They will complete the same pre- and post-intervention questionnaires as the intervention group, allowing comparison of changes in knowledge, motivation, and credibility. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Aged 18 to 35 years
- Proficient in English (reading and comprehension)
- Has access to a stable internet connection
- Possesses a screen-enabled device (e.g., smartphone, tablet, or computer)
- Has access to the Netflix streaming platform
Key exclusion criteria (5 listed)
- Has formal education in medical or health sciences
- Has a prior diagnosis of neurocysticercosis (NCC)
- Has previously participated in any NCC-related health literacy or awareness program
- Lacks access to the Netflix movie platform
- Below 18 years or above 35 years of age
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Medical TV Drama Episode (House M.D.)Also: House M.D. Season 1, Episode 1Participants in the experimental group will watch a selected episode of the medical drama House M.D. (Season 1, Episode 1), which includes a dramatized storyline relevant to neurocysticercosis. The episode is intended to deliver narrative-based health education. After viewing, participants will complete post-test questionnaires assessing changes in knowledge, motivation, and credibility compared to pre-test results. | Behavioural | Intervention (House M.D. Episode) |
Primary outcome
Change in Neurocysticercosis (NCC) Knowledge Score
Time frame: Baseline and immediately post-intervention (within 1 hour)
Knowledge of neurocysticercosis (NCC) will be assessed using the Neurocysticercosis Knowledge Questionnaire, a 10-item multiple-choice instrument developed for this study. Each correct answer is scored as 1 point, and each incorrect or "I don't know" response is scored as 0 points. The total score represents the sum of correct answers, with a minimum possible score of 0 and a maximum possible score of 10. Higher scores indicate better knowledge of NCC across domains such as cause, transmission, symptoms, prevention, and treatment. The primary outcome is the change in total knowledge score from baseline (pre-test) to immediately post-intervention, compared between the intervention and control groups
3 secondary outcomes
Retention of Neurocysticercosis Knowledge
Time frame: 4 weeks post-intervention.
Perceived Credibility of the Medical TV Drama
Time frame: Immediately post-intervention (within 1 hour).
Motivation to Seek Further Health Information
Time frame: Immediately post-intervention (within 1 hour).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Dec 2025.
- Individual participant dataSharing planned: No. Individual participant data will not be shared.
Related trials for Neurocysticercosis
RecruitingObservational study
Natural History of Treated Neurocysticercosis and Long-Term Outcomes
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Oxfendazole in Mild Parenchymal Brain Cysticercosis
Brain Cysticercosis
Not yet recruitingPhase 4
Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Medical TV Drama Episode (House M.D.) in people with Neurocysticercosis and Health Literacy, run by Cephas Health Research Initiative Inc, Ibadan, Nigeria.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Kehinde Kanmodi, PhD (+15059006972, kanmodikehinde@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Neurocysticercosis (NCC) Knowledge Score (time frame: Baseline and immediately post-intervention (within 1 hour)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2025; AzTrials last refreshed its copy on 8 Nov 2026.