Non-specific Low Back Pain (NSLBP)WEBEX-LBPNCT07208435
Web-Based Exercise Program for Non-Specific Low Back Pain
A study testing Web-Based Therapeutic Exercise Program and Traditional Home Exercise Program in people with Non-specific Low Back Pain (NSLBP), run by Medipol University at 1 site in Turkey (Türkiye).
Trial summary
This study evaluates the effectiveness of a web application-based exercise program (delivered via Physitrack) for managing non-specific low back pain (NSLBP) compared to traditional home exercise programs. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Non-specific Low Back Pain (NSLBP)
- What is being tested?
- Web-Based Therapeutic Exercise Program and Traditional Home Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- May 2026to Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults aged 18-45 years diagnosed with non-specific low back pain (NSLBP) for 6 weeks to <12 months.
- Self-reported pain intensity ≥3 on a 0-10 Numeric Pain Rating Scale (NPRS).
- Evidence of functional limitation (Oswestry Disability Index or Roland-Morris Disability Questionnaire).
- Access to a smartphone, tablet, or computer with internet connectivity.
- Ability and willingness to participate in telerehabilitation programs.
Who cannot join
- Specific causes of low back pain (herniated disc with radiculopathy, spinal stenosis, spondylolisthesis, fractures, infections, malignancy).
- Neurological deficits (e.g., severe motor weakness, progressive neurological symptoms).
- Severe psychiatric or cognitive disorders interfering with participation.
- History of spinal surgery within the last year.
- Severe comorbidities contraindicating exercise (e.g., uncontrolled diabetes, cardiovascular disease).
- Pregnant or planning pregnancy during the study period.
- Active substance or alcohol abuse.
- Participation in other structured rehabilitation or physical therapy programs within the last 3 months.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Istanbul Medipol University
Istanbul, Beykoz, 34810
About this study
Official title: Effectiveness of Web-Based Exercise Programs in the Management of Non-Specific Low Back Pain: A Randomized Controlled Trial
This study evaluates the effectiveness of a web application-based exercise program (delivered via Physitrack) for managing non-specific low back pain (NSLBP) compared to traditional home exercise programs. The trial focuses on whether web-based delivery can improve pain, function, quality of life, and adherence, providing evidence for digital rehabilitation as a practical alternative to conventional physiotherapy.
Read the detailed description
Non-specific low back pain (NSLBP) is a prevalent condition associated with pain, functional limitations, and reduced quality of life. Access to in-person physiotherapy can be limited by geographic, financial, or time-related constraints. Web-based exercise programs offer an accessible alternative by delivering personalized exercises, educational content, reminders, and self-monitoring tools via digital platforms.
This study aims to investigate whether a structured web application-based exercise program can improve outcomes for adults with NSLBP compared to traditional home exercises. The trial addresses gaps in current evidence regarding the effectiveness of telerehabilitation, patient engagement, and delivery modes, and seeks to determine if digital interventions can serve as a viable complement or alternative to conventional physiotherapy.
- Conditions
- Non-specific Low Back Pain (NSLBP)
- Being tested
- Web-Based Therapeutic Exercise Program, Traditional Home Exercise Program
- Keywords
- Non-Specific Low Back Pain, NSLBP, Web-Based Exercise Program, Telerehabilitation, Randomized Controlled Trial, Physiotherapy, Home Exercise Program, Pain Management, Functional Improvement, Quality of Life
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Web-Based Therapeutic Exercise ProgramBehavioural
Participants complete an 8-week web-based therapeutic exercise program via Physitrack, with 30-45 minute sessions twice weekly. The program targets core strengthening, spinal mobility, posture correction, and pain reduction. Exercises progress weekly from basic core engagement and breathing techniques to advanced trunk control, dynamic movements, and integration. The platform provides instructional videos, reminders, educational content, and self-monitoring tools to enhance adherence, engagement, and self-management.
Traditional Home Exercise ProgramBehavioural
Participants follow a 6-week traditional home exercise program with 30-40 minute sessions, twice weekly. The program focuses on flexibility, basic trunk and core strengthening, balance, and ergonomic practice. Exercises progress weekly, including cat-cow stretches, pelvic tilts, glute bridges, partial curl-ups, bird-dog, lunges, and posture training. Participants perform exercises independently at home using printed instructions, aiming to reduce pain, improve spinal mobility, and enhance functional outcomes.
| Study group | Role | What they receive |
|---|---|---|
| Web-Based Exercise Program | Experimental | Participants complete an 8-week web-based exercise program via Physitrack. Sessions last 30-45 minutes, twice per week, focusing on core strengthening, spinal mobility, posture correction, and pain reduction. Exercises progress weekly from basic core engagement to advanced trunk control and integration. Receives: Behavioral: Web-Based Therapeutic Exercise Program |
| Traditional Home Exercise Program | Active comparator | Participants complete a 6-week traditional home exercise program. Sessions last 30-40 minutes, focusing on flexibility, basic trunk and core strengthening, balance, and ergonomic practice. Exercises progress weekly, emphasizing pain relief, trunk mobility, and functional strength. Receives: Behavioral: Traditional Home Exercise Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Reduction (Numeric Pain Rating Scale, NPRS)
Change in self-reported low back pain intensity from baseline to 6 weeks, measured using the Numeric Pain Rating Scale (NPRS), where 0 = no pain and 10 = worst imaginable pain. Participants report their average pain over the past 24 hours.
Measured: Baseline and 6 weeks after intervention
Secondary outcomes (4)
Functional Disability (Oswestry Disability Index, ODI)
Change in disability due to low back pain from baseline to 6 weeks, measured using the ODI, which evaluates daily activities such as pain intensity, personal care, lifting, walking, sitting, and sleeping. Higher scores indicate greater disability.
Measured: Baseline and 6 weeks after intervention
Quality of Life (Short Form Health Survey, SF-36)
Change in health-related quality of life from baseline to 6 weeks across physical and mental health domains
Measured: Baseline and 6 weeks after intervention
Patient Satisfaction Questionnaire (PSQ)
Participants' satisfaction with the intervention, including ease of use, communication, and perceived effectiveness.
Measured: 6 weeks end of intervention
Proprioception (Joint Position Sense Test, JPS)
Change in lumbar spine proprioception from baseline to 6 weeks.
Measured: Baseline and 6 weeks after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Oct 2025
- Study startMay 2026 (estimated)
- Primary completionMay 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (17)Papers the sponsor has linked to this study.
- Other trials for Non-specific Low Back Pain (NSLBP)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to either the web-based exercise program (Physitrack) group or the traditional home exercise program group. Each group will receive their assigned intervention throughout the study period, and outcomes will be compared between groups to assess differences in pain reduction, functional improvement, and quality of life.
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Medipol University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yağmur Mustafaoğlu, Medipol University
- Investigators
- Merve Yılmaz Menek, Assoc. Prof, Study director, Assoc. prof. Merve Yılmaz Menek
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07208435
- Sponsor's protocol ID
- E-10840098-202.3.02-3388
- Acronym
- WEBEX-LBP
- Status last verified
- Sep 2025
- First submitted
- 27 Sep 2025
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data (IPD) from this study, including demographic information, pain scores (NPRS), functional disability scores (ODI), quality of life (SF-36), patient satisfaction (PSQ), and proprioception measurements (JPS), may be shared upon reasonable request. Data will be anonymized to protect participant privacy, and access will be provided for academic or research purposes only.
Publications
Searle A et al., 2015
Hayden JA et al., 2005
Qaseem A et al., 2017
Fernández-Rodríguez R et al., 2021
Natour J et al., 2015
Wells C et al., 2014
Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992 Jun;30(6):473-83.
PubMed 1593914Fairbank JC, Pynsent PB. The Oswestry Disability Index. Spine (Phila Pa 1976). 2000 Nov 15;25(22):2940-52; discussion 2952. doi: 10.1097/00007632-200011150-00017.
PubMed 11074683Sissel C. Pilates for Rehabilitation. 2nd ed. 2018.
Bini SA, Schilling PL, Patel SP, Kalore NV, Ast MP, Maratt JD, Schuett DJ, Lawrie CM, Chung CC, Steele GD. Digital Orthopaedics: A Glimpse Into the Future in the Midst of a Pandemic. J Arthroplasty. 2020 Jul;35(7S):S68-S73. doi: 10.1016/j.arth.2020.04.048. Epub 2020 Apr 22.
PubMed 32416956Tseli E, Tsepis E, Anastasopoulos K, et al. Telerehabilitation in patients with low back pain: systematic review and meta-analysis. J Telemed Telecare. 2022;28(3):149-63.
Cottrell MA, Galea OA, O'Leary SP, Hill AJ, Russell TG. Real-time telerehabilitation for the treatment of musculoskeletal conditions is effective and comparable to standard practice: a systematic review and meta-analysis. Clin Rehabil. 2017 May;31(5):625-638. doi: 10.1177/0269215516645148. Epub 2016 May 2.
PubMed 27141087Moffet H, Tousignant M, Nadeau S, Merette C, Boissy P, Corriveau H, Marquis F, Cabana F, Ranger P, Belzile EL, Dimentberg R. In-Home Telerehabilitation Compared with Face-to-Face Rehabilitation After Total Knee Arthroplasty: A Noninferiority Randomized Controlled Trial. J Bone Joint Surg Am. 2015 Jul 15;97(14):1129-41. doi: 10.2106/JBJS.N.01066.
PubMed 26178888Hayden JA, van Tulder MW, Malmivaara AV, Koes BW. Meta-analysis: exercise therapy for nonspecific low back pain. Ann Intern Med. 2005 May 3;142(9):765-75. doi: 10.7326/0003-4819-142-9-200505030-00013.
PubMed 15867409Maniadakis N, Gray A. The economic burden of back pain in the UK. Pain. 2000 Jan;84(1):95-103. doi: 10.1016/S0304-3959(99)00187-6.
PubMed 10601677
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Web-Based Exercise Programs in the Management of Non-Specific Low Back Pain: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07208435
- Acronym / sponsor ID
- WEBEX-LBP / E-10840098-202.3.02-3388
- Conditions
- Non-specific Low Back Pain (NSLBP)
- Keywords
- Non-Specific Low Back Pain, NSLBP, Web-Based Exercise Program, Telerehabilitation, Randomized Controlled Trial, Physiotherapy, Home Exercise Program, Pain Management
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Medipol UniversityUniversity, hospital or other
- Study start
- May 2026 (estimated)
- Primary completion
- May 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 6 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluates the effectiveness of a web application-based exercise program (delivered via Physitrack) for managing non-specific low back pain (NSLBP) compared to traditional home exercise programs. The trial focuses on whether web-based delivery can improve pain, function, quality of life, and adherence, providing evidence for digital rehabilitation as a practical alternative to conventional physiotherapy.
Detailed description
Non-specific low back pain (NSLBP) is a prevalent condition associated with pain, functional limitations, and reduced quality of life. Access to in-person physiotherapy can be limited by geographic, financial, or time-related constraints. Web-based exercise programs offer an accessible alternative by delivering personalized exercises, educational content, reminders, and self-monitoring tools via digital platforms.
This study aims to investigate whether a structured web application-based exercise program can improve outcomes for adults with NSLBP compared to traditional home exercises. The trial addresses gaps in current evidence regarding the effectiveness of telerehabilitation, patient engagement, and delivery modes, and seeks to determine if digital interventions can serve as a viable complement or alternative to conventional physiotherapy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to either the web-based exercise program (Physitrack) group or the traditional home exercise program group. Each group will receive their assigned intervention throughout the study period, and outcomes will be compared between groups to assess differences in pain reduction, functional improvement, and quality of life.
| Arm | Type | Receives |
|---|---|---|
| Web-Based Exercise Program | Experimental | Behavioral: Web-Based Therapeutic Exercise ProgramParticipants complete an 8-week web-based exercise program via Physitrack. Sessions last 30-45 minutes, twice per week, focusing on core strengthening, spinal mobility, posture correction, and pain reduction. Exercises progress weekly from basic core engagement to advanced trunk control and integration. |
| Traditional Home Exercise Program | Active comparator | Behavioral: Traditional Home Exercise ProgramParticipants complete a 6-week traditional home exercise program. Sessions last 30-40 minutes, focusing on flexibility, basic trunk and core strengthening, balance, and ergonomic practice. Exercises progress weekly, emphasizing pain relief, trunk mobility, and functional strength. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Adults aged 18-45 years diagnosed with non-specific low back pain (NSLBP) for 6 weeks to <12 months.
- Self-reported pain intensity ≥3 on a 0-10 Numeric Pain Rating Scale (NPRS).
- Evidence of functional limitation (Oswestry Disability Index or Roland-Morris Disability Questionnaire).
- Access to a smartphone, tablet, or computer with internet connectivity.
- Ability and willingness to participate in telerehabilitation programs.
Key exclusion criteria (8 listed)
- Specific causes of low back pain (herniated disc with radiculopathy, spinal stenosis, spondylolisthesis, fractures, infections, malignancy).
- Neurological deficits (e.g., severe motor weakness, progressive neurological symptoms).
- Severe psychiatric or cognitive disorders interfering with participation.
- History of spinal surgery within the last year.
- Severe comorbidities contraindicating exercise (e.g., uncontrolled diabetes, cardiovascular disease).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Web-Based Therapeutic Exercise ProgramParticipants complete an 8-week web-based therapeutic exercise program via Physitrack, with 30-45 minute sessions twice weekly. The program targets core strengthening, spinal mobility, posture correction, and pain reduction. Exercises progress weekly from basic core engagement and breathing techniques to advanced trunk control, dynamic movements, and integration. The platform provides instructional videos, reminders, educational content, and self-monitoring tools to enhance adherence, engagement, and self-management. | Behavioural | Web-Based Exercise Program |
| Traditional Home Exercise ProgramParticipants follow a 6-week traditional home exercise program with 30-40 minute sessions, twice weekly. The program focuses on flexibility, basic trunk and core strengthening, balance, and ergonomic practice. Exercises progress weekly, including cat-cow stretches, pelvic tilts, glute bridges, partial curl-ups, bird-dog, lunges, and posture training. Participants perform exercises independently at home using printed instructions, aiming to reduce pain, improve spinal mobility, and enhance functional outcomes. | Behavioural | Traditional Home Exercise Program |
Primary outcome
Pain Reduction (Numeric Pain Rating Scale, NPRS)
Time frame: Baseline and 6 weeks after intervention
Change in self-reported low back pain intensity from baseline to 6 weeks, measured using the Numeric Pain Rating Scale (NPRS), where 0 = no pain and 10 = worst imaginable pain. Participants report their average pain over the past 24 hours.
4 secondary outcomes
Functional Disability (Oswestry Disability Index, ODI)
Time frame: Baseline and 6 weeks after intervention
Quality of Life (Short Form Health Survey, SF-36)
Time frame: Baseline and 6 weeks after intervention
Patient Satisfaction Questionnaire (PSQ)
Time frame: 6 weeks end of intervention
Proprioception (Joint Position Sense Test, JPS)
Time frame: Baseline and 6 weeks after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- BackgroundSearle A et al., 2015
- BackgroundHayden JA et al., 2005
- BackgroundQaseem A et al., 2017
- BackgroundFernández-Rodríguez R et al., 2021
- BackgroundNatour J et al., 2015
- BackgroundWells C et al., 2014
- Background: PubMed 1593914Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992 Jun;30(6):473-83.
- Background: PubMed 11074683Fairbank JC, Pynsent PB. The Oswestry Disability Index. Spine (Phila Pa 1976). 2000 Nov 15;25(22):2940-52; discussion 2952. doi: 10.1097/00007632-200011150-00017.
- BackgroundSissel C. Pilates for Rehabilitation. 2nd ed. 2018.
- Background: PubMed 32416956Bini SA, Schilling PL, Patel SP, Kalore NV, Ast MP, Maratt JD, Schuett DJ, Lawrie CM, Chung CC, Steele GD. Digital Orthopaedics: A Glimpse Into the Future in the Midst of a Pandemic. J Arthroplasty. 2020 Jul;35(7S):S68-S73. doi: 10.1016/j.arth.2020.04.048. Epub 2020 Apr 22.
- BackgroundTseli E, Tsepis E, Anastasopoulos K, et al. Telerehabilitation in patients with low back pain: systematic review and meta-analysis. J Telemed Telecare. 2022;28(3):149-63.
- Background: PubMed 27141087Cottrell MA, Galea OA, O'Leary SP, Hill AJ, Russell TG. Real-time telerehabilitation for the treatment of musculoskeletal conditions is effective and comparable to standard practice: a systematic review and meta-analysis. Clin Rehabil. 2017 May;31(5):625-638. doi: 10.1177/0269215516645148. Epub 2016 May 2.
- Official website for the web application used in the intervention group.Link provided by the sponsor.
- Individual participant dataSharing planned: Yes. De-identified individual participant data (IPD) from this study, including demographic information, pain scores (NPRS), functional disability scores (ODI), quality of life (SF-36), patient satisfaction (PSQ), and proprioception measurements (JPS), may be shared upon reasonable request. Data will be anonymized to protect participant privacy, and access will be provided for academic or research purposes only.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Merve Yılmaz Menek, Assoc. Prof study director
Assoc. prof. Merve Yılmaz Menek
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Web-Based Therapeutic Exercise Program and Traditional Home Exercise Program in people with Non-specific Low Back Pain (NSLBP), run by Medipol University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yağmur Mustafaoğlu, PT, MSc (Cand.) (+905397974655, yagmurmustafaoglu84@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Reduction (Numeric Pain Rating Scale, NPRS) (time frame: Baseline and 6 weeks after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07208435, which also lists 17 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.