FatigueNCT07188831
Effect of Agarwood (Aquilaria Sinensis) Inhalation Aromatherapy on Workplace Fatigue and Sleep Quality Among Hospital Employees: A Randomized Controlled Trial
A study testing Agarwood Aromatherapy Inhalation in people with Fatigue and Occupational Stress or Workplace Stress, run by Da-Yeh University.
Trial summary
Hospital staff often experience workplace fatigue and poor sleep quality, which can harm their health, reduce job performance, and increase risks to patient safety. Aromatherapy is a simple, non-invasive complementary therapy that may help reduce fatigue and improve sleep. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Fatigue, Occupational Stress or Workplace Stress, Sleep Quality
- What is being tested?
- Agarwood Aromatherapy Inhalation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 78 participants
- Where
- No sites listed yet
- Study dates
- Sep 2025to Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- ≥20 years old, hospital employee working ≥30 hrs/week, employed ≥3 months
- Not using sedatives/hypnotics
- Normal olfactory function (verified with coffee/vinegar smell test)
- Clear consciousness, can read and understand Chinese, no major communication barriers
- Not participating in other aromatherapy or relaxation intervention studies
Who cannot join
- Major psychiatric disorders (e.g., major depression, schizophrenia)
- Malignancy under active radio/chemotherapy
- CNS diseases (e.g., brain tumor)
- History of asthma, fragrance allergy, pregnancy
- Chronic rhinitis, nasal surgery, anosmia
- Permanent night-shift workers (≥ midnight to 5am, as defined by ILO, 1995)
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Randomized Controlled Trial Examining the Impact of Agarwood Aromatherapy Inhalation on Sleep Quality and Occupational Fatigue in Hospital Staff
Hospital staff often experience workplace fatigue and poor sleep quality, which can harm their health, reduce job performance, and increase risks to patient safety. Aromatherapy is a simple, non-invasive complementary therapy that may help reduce fatigue and improve sleep. Agarwood (Aquilaria spp.) has calming and relaxing properties, but there is little clinical research on its effectiveness for hospital staff.
This randomized, double-blind, controlled trial will evaluate whether agarwood aromatherapy inhalation can improve fatigue and sleep quality among hospital employees in Taiwan. About 78 participants will be recruited and randomly assigned to one of two groups:
Read more
- Experimental group: Agarwood sachet containing agarwood wood chips and essential oil.
- Control group: Placebo sachet containing almond oil.
Participants will place the sachet about 60 cm from the nose during sleep for 7 nights. Data will be collected using questionnaires on workplace fatigue and sleep quality (Pittsburgh Sleep Quality Index, PSQI). The main questions this study aims to answer are: 1. Does agarwood aromatherapy reduce workplace fatigue in hospital staff? 2. Does agarwood aromatherapy improve sleep quality compared with placebo?
Findings are expected to provide scientific evidence for using agarwood inhalation as a safe and convenient strategy to improve staff well-being and support a healthier hospital environment.
- Being tested
- Agarwood Aromatherapy Inhalation
- Medical subject headings
- Fatigue, Occupational Stress, Sleep Initiation and Maintenance Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Agarwood Aromatherapy InhalationOther
The experimental group will receive agarwood essential oil sachets as the aromatherapy intervention, and participants will place the sachet 60 cm from the nose during sleep for one week.
| Study group | Role | What they receive |
|---|---|---|
| Group of agarwood | Experimental | Inhalation of agarwood (Aquilaria crassna, "Guangdong green kyara") wood chips + 2 drops agarwood essential oil in sachet, and exposure during sleep for 7-8 hrs/night × 7 nights Receives: Other: Agarwood Aromatherapy Inhalation |
| Group of sachet | Active comparator | Inhalation of sachet containing diffuser sticks soaked with sweet almond carrier oil (odorless placebo), and same exposure schedule Receives: Other: Agarwood Aromatherapy Inhalation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Workplace Fatigue
Change in fatigue levels measured by the Chinese version of the Copenhagen Burnout Inventory (21 items across four domains: personal, work-related, client-related, and overcommitment). Higher scores indicate greater fatigue.
Measured: Baseline and after 1-week intervention
Secondary outcomes (1)
Sleep Quality
Change in sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI, 19 items, 7 domains). Total scores range from 0 to 21, with higher scores indicating poorer sleep quality.
Measured: Baseline and after 1-week intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2025
- Study startSep 2025 (estimated)
- Primary completionJul 2026 (estimated)
- Study completionJul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FatigueStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 78 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Da-Yeh University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yi-chen Wu, Da-Yeh University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07188831
- Sponsor's protocol ID
- DYU-AGARWOOD-2025
- Status last verified
- Sep 2025
- First submitted
- 16 Sep 2025
- Last updated
- 23 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared because of privacy concerns and institutional data protection policies.
Study at a glance
From the registry record, last updated by the sponsor on 23 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Controlled Trial Examining the Impact of Agarwood Aromatherapy Inhalation on Sleep Quality and Occupational Fatigue in Hospital Staff
- ClinicalTrials.gov ID
- NCT07188831
- Acronym / sponsor ID
- DYU-AGARWOOD-2025
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 78 participants (estimated)
- Lead sponsor
- Da-Yeh UniversityUniversity, hospital or other
- Study start
- Sep 2025 (estimated)
- Primary completion
- Jul 2026 (estimated)
- Study completion
- Jul 2026 (estimated)
- First posted
- 23 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Hospital staff often experience workplace fatigue and poor sleep quality, which can harm their health, reduce job performance, and increase risks to patient safety. Aromatherapy is a simple, non-invasive complementary therapy that may help reduce fatigue and improve sleep. Agarwood (Aquilaria spp.) has calming and relaxing properties, but there is little clinical research on its effectiveness for hospital staff.
This randomized, double-blind, controlled trial will evaluate whether agarwood aromatherapy inhalation can improve fatigue and sleep quality among hospital employees in Taiwan. About 78 participants will be recruited and randomly assigned to one of two groups:
- Experimental group: Agarwood sachet containing agarwood wood chips and essential oil.
- Control group: Placebo sachet containing almond oil.
Participants will place the sachet about 60 cm from the nose during sleep for 7 nights. Data will be collected using questionnaires on workplace fatigue and sleep quality (Pittsburgh Sleep Quality Index, PSQI). The main questions this study aims to answer are: 1. Does agarwood aromatherapy reduce workplace fatigue in hospital staff? 2. Does agarwood aromatherapy improve sleep quality compared with placebo?
Findings are expected to provide scientific evidence for using agarwood inhalation as a safe and convenient strategy to improve staff well-being and support a healthier hospital environment.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group of agarwood | Experimental | Other: Agarwood Aromatherapy InhalationInhalation of agarwood (Aquilaria crassna, "Guangdong green kyara") wood chips + 2 drops agarwood essential oil in sachet, and exposure during sleep for 7-8 hrs/night × 7 nights |
| Group of sachet | Active comparator | Other: Agarwood Aromatherapy InhalationInhalation of sachet containing diffuser sticks soaked with sweet almond carrier oil (odorless placebo), and same exposure schedule |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- ≥20 years old, hospital employee working ≥30 hrs/week, employed ≥3 months
- Not using sedatives/hypnotics
- Normal olfactory function (verified with coffee/vinegar smell test)
- Clear consciousness, can read and understand Chinese, no major communication barriers
- Not participating in other aromatherapy or relaxation intervention studies
Key exclusion criteria (6 listed)
- Major psychiatric disorders (e.g., major depression, schizophrenia)
- Malignancy under active radio/chemotherapy
- CNS diseases (e.g., brain tumor)
- History of asthma, fragrance allergy, pregnancy
- Chronic rhinitis, nasal surgery, anosmia
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Agarwood Aromatherapy InhalationThe experimental group will receive agarwood essential oil sachets as the aromatherapy intervention, and participants will place the sachet 60 cm from the nose during sleep for one week. | Other | Group of agarwood, Group of sachet |
Primary outcome
Workplace Fatigue
Time frame: Baseline and after 1-week intervention
Change in fatigue levels measured by the Chinese version of the Copenhagen Burnout Inventory (21 items across four domains: personal, work-related, client-related, and overcommitment). Higher scores indicate greater fatigue.
1 secondary outcome
Sleep Quality
Time frame: Baseline and after 1-week intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Sep 2025.
- Individual participant dataSharing planned: No. Individual participant data will not be shared because of privacy concerns and institutional data protection policies.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Agarwood Aromatherapy Inhalation in people with Fatigue and Occupational Stress or Workplace Stress, run by Da-Yeh University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yi-chen Wu, PhD (+886-4-8511888 ext. 7215, yichenwu@mail.dyu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Workplace Fatigue (time frame: Baseline and after 1-week intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Sep 2025.