Neuropathic Pain in CancerSUONO-PT 01NCT07187986
Sound Acupuncture in Painful Chemotherapy-Related Neuropathies
A study testing Sound acupuncture in people with Neuropathic Pain in Cancer, run by Ente Ospedaliero Ospedali Galliera at 1 site in Italy.
Trial summary
The objective of this clinical trial is to evaluate the efficacy of sound acupuncture in combination with traditional medical therapy in the treatment of chemotherapy-induced peripheral neuropathies. Read more about this study
- Who is it for?
- Ages 30 to 80 years
- Conditions the study is for
- Neuropathic Pain in Cancer
- What is being tested?
- Sound acupuncture
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteItaly
- Study dates
- 17 Mar 2022to 16 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 30-80 years
- Clinical and electrophysiological diagnosis of chemotherapy-induced neuropathy
- Patients being treated with Best Medical Therapy for neuropathic pain
- Written informed consent
Who cannot join
- Women who are pregnant or breastfeeding
- Patients with intellectual disabilities or cognitive impairment that impair their ability to comply with the consent process
- Pacemaker users
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of Sound Acupuncture in Painful Chemotherapy-Related Neuropathies: A Non-Invasive Alternative to Acupuncture? Pilot Study
The objective of this clinical trial is to evaluate the efficacy of sound acupuncture in combination with traditional medical therapy in the treatment of chemotherapy-induced peripheral neuropathies.
Sound acupuncture is a non-invasive technique that involves stimulating energy points, used in acupuncture, with the help of specific tuning forks and the frequencies they emit.
Read more
The energy points are those used in Chinese medicine and, more specifically, in acupuncture.
The aim is to restore the recipient's complex bioenergetic system to an optimal state of well-being and balance
Participants:
20 patients will receive only the best medical therapy; 20 patients will receive BMT and sound acupuncture treatment
- Conditions
- Neuropathic Pain in Cancer
- Being tested
- Sound acupuncture
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sound acupunctureOther
Best medical therapy + soundpuncture
| Study group | Role | What they receive |
|---|---|---|
| Sound acupuncture | Experimental | Best medical therapy + Sound Acupuncture Receives: Other: Sound acupuncture |
| BMT | No intervention | Best medical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain reduction
At least a 30% reduction from baseline on the NPS scale for neuropathic pain
Measured: 1 year
Secondary outcomes (2)
Back Depression inventory
Effectiveness of sound therapy combined with pharmacological treatment through administration of the BDI-II scale
Measured: 1 year
Quality of life assessment
EQ-5D scale for assessing the impact on quality of life
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2025
- Study start17 Mar 2022
- Primary completion15 Jul 2025
- Study completion16 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neuropathic Pain in CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ente Ospedaliero Ospedali Galliera
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Andrea Assini, Ente Ospedaliero Ospedali Galliera
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07187986
- Sponsor's protocol ID
- 67UCS2018
- Acronym
- SUONO-PT 01
- Status last verified
- Sep 2025
- First submitted
- 4 Aug 2025
- Last updated
- 23 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Sound Acupuncture in Painful Chemotherapy-Related Neuropathies: A Non-Invasive Alternative to Acupuncture? Pilot Study
- ClinicalTrials.gov ID
- NCT07187986
- Acronym / sponsor ID
- SUONO-PT 01 / 67UCS2018
- Conditions
- Neuropathic Pain in Cancer
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Ente Ospedaliero Ospedali GallieraUniversity, hospital or other
- Study start
- 17 Mar 2022 (actual)
- Primary completion
- 15 Jul 2025 (actual)
- Study completion
- 16 Jul 2025 (actual)
- First posted
- 23 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of this clinical trial is to evaluate the efficacy of sound acupuncture in combination with traditional medical therapy in the treatment of chemotherapy-induced peripheral neuropathies.
Sound acupuncture is a non-invasive technique that involves stimulating energy points, used in acupuncture, with the help of specific tuning forks and the frequencies they emit.
The energy points are those used in Chinese medicine and, more specifically, in acupuncture.
The aim is to restore the recipient's complex bioenergetic system to an optimal state of well-being and balance
Participants:
20 patients will receive only the best medical therapy; 20 patients will receive BMT and sound acupuncture treatment
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sound acupuncture | Experimental | Other: Sound acupunctureBest medical therapy + Sound Acupuncture |
| BMT | No intervention | –Best medical therapy |
Who may qualify
- Ages
- 30 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age 30-80 years
- Clinical and electrophysiological diagnosis of chemotherapy-induced neuropathy
- Patients being treated with Best Medical Therapy for neuropathic pain
- Written informed consent
Key exclusion criteria (3 listed)
- Women who are pregnant or breastfeeding
- Patients with intellectual disabilities or cognitive impairment that impair their ability to comply with the consent process
- Pacemaker users
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sound acupunctureBest medical therapy + soundpuncture | Other | Sound acupuncture |
Primary outcome
Pain reduction
Time frame: 1 year
At least a 30% reduction from baseline on the NPS scale for neuropathic pain
2 secondary outcomes
Back Depression inventory
Time frame: 1 year
Quality of life assessment
Time frame: 1 year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sound acupuncture in people with Neuropathic Pain in Cancer, run by Ente Ospedaliero Ospedali Galliera at 1 site in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain reduction (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Sep 2025.