Symptomatic Non-ruptured Abdominal Aortic AneurysmsDETHINENCT07184723
Investigating Practice Patterns in Symptomatic Non-ruptured Abdominal Aortic Aneurysms (AAA) in Europe
An observational study of Symptomatic Non-ruptured Abdominal Aortic Aneurysms, run by Wilhelminenspital Vienna at 1 site in Austria.
Trial summary
Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies. Unlike ruptured AAAs, snrAAA lack large-scale population-based studies, primarily due to inconsistent application of standardised medical… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Symptomatic Non-ruptured Abdominal Aortic Aneurysms
- How many people
- 130 participants
- Where
- 1 siteAustria
- Study dates
- 1 Aug 2024to Jun 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: European vascular centres offering elective and emergency AAA repair
Who may be able to join
- Last 5 patients (aged >18 years) treated at a participating centre for symptomatic non-ruptured AAA (or the last patients in the preceding 5 years if they have treated less than 5 patients in 5 years)
Who cannot join
- None
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Maria Elisabeth Leinweber, MD contact
Austria1 site, 1 recruiting
- Recruiting
Department of Vascular and Endovascular Surgery, Clinic Ottakring
Vienna, State of Vienna, 1160
Afshin Assadian, MD, +43 1 49150 4110, kor.1ch@gesundheitsverbund.at
About this study
Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies. Unlike ruptured AAAs, snrAAA lack large-scale population-based studies, primarily due to inconsistent application of standardised medical classifications (e.g., ICD-10) and international variability in definitions, diagnostic approaches, and treatment protocols. Optimal diagnostic pathways, preoperative risk assessments, and treatment strategies remain poorly defined, with minimal guidance from existing guidelines.
This study aims to conduct a multinational cross-sectional online survey with optional retrospective validation to assess current opinions on an institutional scale regarding the definition and management of patients with snrAAA in Europe. All European vascular centres offering elective and emergency AAA repair are eligible to participate. Multiple survey entries from the same institution are not allowed. Centres are also invited to participate in a retrospective observational validation, reporting diagnostic and therapeutic details of their last five snrAAA cases.
- Keywords
- abdominal aortic aneurysm, symptomatic non-ruptured, vascular surgery, Europe
- Medical subject headings
- Aortic Aneurysm, Abdominal
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants that define non-ruptured symptomatic AAA on clinical symptoms alone assessed by the snrAAA Questionaire
The objective of this study is to provide insights into current practice strategies in the definition, diagnosis, preoperative optimization, and surgical care of patients with non-ruptured symptomatic AAA in Europe.
Primary outcome measures will be count and proportion.
Measured: From August 2024 to June 2026
Secondary outcomes (1)
Number of participants where the stated practices align with actual treatment patterns assessed by the snrAAA Questionaire and electronic Case Report Form
In order to validate the data collected on the institutional standard of care for symptomatic non-ruptured AAA cases, centres are kindly invited to participate in a retrospective observational analysis in which they are asked to report the diagnostic and therapeutic procedure of the last 5 patients treated at their institution for symptomatic non-ruptured AAA (or the last patients in the preceding 5 years if they have treated less than 5 patients in 5 years).
Secondary outcome measures will be count and proportion.
Measured: From August 2024 to June 2026
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Sep 2025
- Study start1 Aug 2024
- Primary completionJun 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Symptomatic Non-ruptured Abdominal Aortic AneurysmsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 130 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Wilhelminenspital Vienna
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Prim PD Dr Afshin Assadian, Wilhelminenspital Vienna
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07184723
- Sponsor's protocol ID
- EK_24_063_VK
- Acronym
- DETHINE
- Status last verified
- Jun 2025
- First submitted
- 9 Jul 2025
- Last updated
- 22 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigating Practice Patterns in Symptomatic Non-ruptured Abdominal Aortic Aneurysms (AAA) in Europe
- ClinicalTrials.gov ID
- NCT07184723
- Acronym / sponsor ID
- DETHINE / EK_24_063_VK
- Keywords
- abdominal aortic aneurysm, symptomatic non-ruptured, vascular surgery, Europe
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 130 participants (estimated)
- Lead sponsor
- Wilhelminenspital ViennaUniversity, hospital or other
- Study start
- 1 Aug 2024 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 22 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies. Unlike ruptured AAAs, snrAAA lack large-scale population-based studies, primarily due to inconsistent application of standardised medical classifications (e.g., ICD-10) and international variability in definitions, diagnostic approaches, and treatment protocols. Optimal diagnostic pathways, preoperative risk assessments, and treatment strategies remain poorly defined, with minimal guidance from existing guidelines.
This study aims to conduct a multinational cross-sectional online survey with optional retrospective validation to assess current opinions on an institutional scale regarding the definition and management of patients with snrAAA in Europe. All European vascular centres offering elective and emergency AAA repair are eligible to participate. Multiple survey entries from the same institution are not allowed. Centres are also invited to participate in a retrospective observational validation, reporting diagnostic and therapeutic details of their last five snrAAA cases.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- European vascular centres offering elective and emergency AAA repair
Key inclusion criteria (1 listed)
- Last 5 patients (aged >18 years) treated at a participating centre for symptomatic non-ruptured AAA (or the last patients in the preceding 5 years if they have treated less than 5 patients in 5 years)
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of participants that define non-ruptured symptomatic AAA on clinical symptoms alone assessed by the snrAAA Questionaire
Time frame: From August 2024 to June 2026
The objective of this study is to provide insights into current practice strategies in the definition, diagnosis, preoperative optimization, and surgical care of patients with non-ruptured symptomatic AAA in Europe. Primary outcome measures will be count and proportion.
1 secondary outcome
Number of participants where the stated practices align with actual treatment patterns assessed by the snrAAA Questionaire and electronic Case Report Form
Time frame: From August 2024 to June 2026
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2025.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Maria Elisabeth Leinweber, MD contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Symptomatic Non-ruptured Abdominal Aortic Aneurysms, run by Wilhelminenspital Vienna at 1 site in Austria.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Austria. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Maria Elisabeth Leinweber, MD (+43 1 49150 4110, maria-elisabeth.leinweber@gesundheitsverbund.at), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants that define non-ruptured symptomatic AAA on clinical symptoms alone assessed by the snrAAA Questionaire (time frame: From August 2024 to June 2026). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2025.