Postural Orthostatic Tachycardia Syndrome (POTS)NCT07182578
Programming Aquatic Therapy for POTS
A study testing Aquatic Occupational Therapy in people with Postural Orthostatic Tachycardia Syndrome (POTS), run by California State University, Dominguez Hills at 1 site in United States.
Trial summary
The goal of this pilot study is to create, implement, and evaluate an aquatic therapy for Postural Orthostatic Tachycardia Syndrome (POTS) program feasibility and ability to improve quality of life as determined by reduced orthostatic tachycardia, reduced POTS symptoms, and improved quality of life measures. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Postural Orthostatic Tachycardia Syndrome (POTS)
- What is being tested?
- Aquatic Occupational Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5 participants
- Where
- 1 siteUnited States
- Study dates
- 12 Sep 2025to 8 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with POTS, Age 18-64, Participants must be English speaking, participants must obtain a physician permission letter* * The physician letter will only state that the participant is cleared to participate in aquatic therapy, it will not confirm or state what disease the individual has in the medical records or other HIPAA information.
Who cannot join
- Not diagnosed with POTS, Not between the ages of 18-64*, Epilepsym Bowel incontinence
- The reason for the age requirement is because individuals:
- under 18 have different diagnostic criteria and mechanisms for POTS than the age range specified and may respond differently to treatment
- over age 65 have different mechanisms behind POTS than younger individuals, and frequently have health conditions or factors that can be difficult to differentiate from POTS symptoms/diagnosis and would require lab work and continuous physician involvement. POTS is less common in older adults.
- The typical age of onset for POTS is generally considered to be between the ages of 15-50 years of age
- For participant's safety, the researcher needs to be able to communicate with them in the aquatic setting. English is the researcher's only language and electronic translators are not accessible/usable in the pool setting.
Trial locations and contacts
1 site in 1 country.
United States1 site
California Aquatic Therapy & Wellness Center
Long Beach, California, 90805
About this study
The goal of this pilot study is to create, implement, and evaluate an aquatic therapy for Postural Orthostatic Tachycardia Syndrome (POTS) program feasibility and ability to improve quality of life as determined by reduced orthostatic tachycardia, reduced POTS symptoms, and improved quality of life measures.
The main questions it aims to answer are:
Read more
Does aquatic occupational therapy reduce orthostatic tachycardia and POTS symptoms? Does aquatic occupational therapy lead to higher quality of live measures for people with POTS? Is this aquatic occupational therapy program feasible for clinicians and people with POTS?
There is no comparison group for this pilot study.
Participants will complete:
An occupational Therapy evaluation before and after program completion (3 hours total) 30 minutes at home/remote 30 minutes on-site/in-person 30 minutes of individualized occupational therapy on land
Participate in 3 aquatic therapy sessions per week, 60 minutes each for 12 weeks
- Being tested
- Aquatic Occupational Therapy
- Keywords
- Aquatic Therapy, Occupational therapy, POTS, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Rehabilitation, Hydrotherapy
- Medical subject headings
- Postural Orthostatic Tachycardia Syndrome, Autonomic Nervous System Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Aquatic Occupational TherapyOther
Aquatic Occupational Therapy sessions will be 60 minutes long, with 45 minutes spent in the pool. Sessions will include a gentle floating, stretching, or aqua yoga warm-up and an ai chi cooldown. Exercises in the first month will include a focus on balance, breathing, and sensory work. Exercises in the second month will focus on building strength and endurance, while the third month will combine all of the above with dual-task completion. Activities will be graded down (made less difficult) or graded up (made more challenging) according to individual participant needs.
| Study group | Role | What they receive |
|---|---|---|
| Aquatic Occupational Therapy Intervention | Experimental | All participants will participate in the aquatic occupational therapy arm. The aquatic occupational therapy intervention is divided into three progressive months:
Month 1: Breathing techniques, proprioception, balance, and vestibular activities.
Easy breathing and balancing moves Example: Belly breathing, water walking, toe lifts, mountain aqua yoga pose Month 2: Strength and endurance training Building strength and ability to exercise longer Example: Water marching, core exercises using dumbbells or paddles Month 3: Advanced strengthening and endurance tasks with integrated cognitive, balance, and dual-task challenges.
Harder exercises and doing two things at once, like thinking and moving together Example: Dumbbell exercises while playing a word association game Receives: Other: Aquatic Occupational Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
World Health Organization Quality of Life - Brief (WHOQOL-BREF)
The WHOQOL-BREF is a 26-item questionnaire that will be completed digitally. It is scored by first assigning numerical values (1-5) to each response, with higher scores generally indicating a better quality of life. Then, raw domain scores are calculated by averaging the responses within each domain (Physical, Psychological, Social, and Environmental). Finally, these raw domain scores are transformed into scaled scores ranging from 0 to 100 by multiplying by 4. Higher scores on the 0-100 scale indicate a higher quality of life.
The measure will be reported as a quality of life score.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
The DePaul Symptom Questionnaire (Short Form) (DSQ-SF)
14-item-questionnaire which measures post-exertional malaise symptoms over the last 6 months. Each question requires two ratings, one for frequency (0 = none of the time and 4 = all of the time) and one for severity (0 = symptom not present and 4 = very severe). A frequency of at least 2 and a severity of at least 2 on any one of the 5 questions on the DSQ-SF subscale indicate that post exertional malaise is present. For each symptom, the frequency and severity scores are averaged, and then multiplied by 25 to create a composite score out of 100.
The measure will be reported as a post exertional malaise score.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention.
Composite Autonomic Symptom Score-31
Measures neurodegenerative system symptoms through 31 patient-reported questions. Assessment is through six weighted domains: orthostatic intolerance [10 points]; vasomotor [6 points]; secretomotor [7 points]; gastrointestinal [28 points]; bladder [9 points] and pupillomotor [15 points]. A higher score indicates worse autonomic dysfunction. Simple yes or no questions are scored as 0 points for no and 1 point for yes. Questions about a specific site of symptoms or symptoms under specific circumstances are scored as 0 if not present and as 1 if present for each site or circumstance. All questions regarding the frequency of symptoms were scored as 0 points for rarely or never, 1 point for occasionally or sometimes, 2 points for frequently or "a lot of the time," and 3 points for almost always or constantly. All questions regarding the severity of symptoms were scored as 1 point for mild, 2 points for moderate, and 3 points for severe.
The measure will be reported as a COMPASS score
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention.
Malmo POTS Scale (MAPS)
This 12-item questionnaire assesses the specific POTS symptom burden over the past 3 months. Each question uses a visual analog scale from 0-10, with a maximum score of 120. A score of 42 or higher is considered indicative of POTS.
The measure will be reported as a MAPS score.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
ADLS, IADLS, and Vestibular Questionnaire
This is a 26-item questionnaire that will be filled out digitally. 21 questions cover about to participate in occupations listed in the Occupational Therapy Practice Framework using a scale from 1-10, where 1 is unable to complete the task, 5 is able to complete task with moderate difficulty (noticeable symptoms and extra effort is required) 10 is no problems/symptoms completing the task. It also contains 5 vestibular related questions using a scale from 1-7, with 1 being not at all dizzy, 4 being moderately dizzy, and 7 being extremely dizzy. The measure will be reported as an AIVQ score.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
Active Stand Test
The patient will begin laying down in a relaxed and comfortable position. Blood pressure (BP) and heart rate (HR) are taken after 5 minutes. Next, the patient will be asked to stand promptly, and will have their BP and HR measured immediately. The therapist will note any comments like "feeling dizzy". The BP and HR will be taken again and documented after three minutes, and again after ten minutes of standing. If there is any event, such as severe dizziness, paleness, etc, the BP and HR will be taken and documented just before the patient sits down.
The measure will be reported as the position, time, and the correlated heart rate and blood pressure.
Measured: From enrollment until the end of treatment at 12 weeks
Single leg stance test
This test measures a person's ability to balance standing on one leg without assistance. The participant will stand on one leg with their hands on their hips while being timed. The test is repeated 3 times for each leg and averaged. The measure will be reported as time standing per leg.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
Heart Rate
Heart rate (HR) will be measured on land while the participant is laying down, sitting up, and standing. HR in the water will be taken while seated and standing. An aquatic HR maximum and HR zones will be calculated for each participant. This measure will be reported as a land-based and aquatic HR maximum.
Measured: From enrollment to the end of treatment at 12 weeks
Borg's rate of perceived exertion scale
This scale is used to tell how tiring an activity feels. The scale ranges from 6 (no exertion at all), to 20 (maximal heaviness). This will be reported as the RPE score.
Measured: From enrollment to the end of treatment at 12 weeks
Secondary outcomes (11)
The Stroop Test
The Stroop Test is a measure of working memory and attention. A participant is asked to read words of various colors, say the color of the letters when they are the same, and when the colors don't match the words. They are timed and errors are tracked. This will be reported as the SCWT score.
Measured: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
Trail Making Test Parts A & B
The participant is given a paper with numbers and letters, and is instructed to connect the letters and numbers in order (1-A-2-B-3-C, etc.), as quickly as possible, without lifting the pend or pencil from the paper. Errors will be pointed out immediately and the participant is allowed to correct it, but the time it takes to correct is still included in the completion time for the task. This will be reported as the TMT-A and TMT-B scores.
Measured: From enrollment to the end of the intervention at 12 weeks
Enrollment
Total number of participants who complete the informed consent, evaluation session, and agree to participate in program according to schedule discussed with participant
Measured: From enrollment to the end of treatment at 12 weeks
Attrition Rate
The number of enrolled participants who do not complete the program
Measured: From enrollment to the end of treatment at 12 weeks
Session attendance rate
This will be calculated by the number of sessions attended out of the total number of sessions for the program.
Measured: From enrollment to the end of treatment at 12 weeks
Cost analysis
This measure will include resource tracking and total costs divided by the number of completers.
Measured: From enrollment to the end of treatment at 12 weeks
Health utilization changes
This will include a calculation of health utilization changes from before the program compared to after the program
Measured: From enrollment to the end of treatment at 12 weeks
Satisfaction Analysis
Thematic analysis of open-ended feedback from participants and stakeholders will determine the most common themes and areas for improvement within the program.
Measured: From enrollment to the end of treatment at 12 weeks
Exercise self-efficacy
Measure will be completed before the program and compared to the result after, leading to an ESE score.
Measured: From enrollment to the end of treatment at 12 weeks
Goal Attainment Scaling
Goal attainment scaling is a method to turn individualized goals into a 5-point evaluation method, using a score of -2 to + 2 to quantify progress towards the specific goals. It measures the outcomes against expected results, where 0 is the expected outcome, -2 is much less than the expected outcome, and +2 is much more than the expected outcome.
Measured: From enrollment to the end of treatment at 12 weeks
Beighton Score
The Beighton score is a screener for hypermobility and can be done quickly and simply with no testing materials needed. It consists of a 5-point scale, requires 5 maneuvers. It involves the evaluation of only a small number of joints, so any hypermobile joints not in this group may be overlooked.
Measured: From enrollment to the end of treatment at 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2025
- Study start12 Sep 2025
- Primary completion8 Feb 2026
- Study completion8 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postural Orthostatic Tachycardia Syndrome (POTS)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 5 participants (actual)
Sponsor and investigators
- Lead sponsor
- California State University, Dominguez Hills
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, EvaRose Celeste, California State University, Dominguez Hills
- Investigators
- EvaRose Celeste, OT Doctoral student, Principal investigator, California State University, Dominguez HillsTracy Becerra-Culqui, PhD, MPH, BS OT, Study chair, California State University, Dominguez Hills
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07182578
- Sponsor's protocol ID
- IRB-FY2025-162
- Status last verified
- Mar 2026
- First submitted
- 10 Sep 2025
- Last updated
- 3 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The final dataset will include individual-level vaccination and demographic data, as well as other health characteristics. We will make the data and associated documentation available to users only under a data-sharing agreement that provides for: (1) a commitment to using the data only for research purposes and not to identify any individual participant; (2) a commitment to securing the data using appropriate computer technology; and (3) a commitment to destroying or returning the data after analyses are completed. We will share the final dataset under our own auspices and by our own determination based on review of a detailed research plan submitted by the requestor.
Study at a glance
From the registry record, last updated by the sponsor on 3 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Programming Aquatic Therapy for POTS
- ClinicalTrials.gov ID
- NCT07182578
- Acronym / sponsor ID
- IRB-FY2025-162
- Keywords
- Aquatic Therapy, Occupational therapy, POTS, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Rehabilitation, Hydrotherapy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 5 participants (actual)
- Lead sponsor
- California State University, Dominguez HillsUniversity, hospital or other
- Study start
- 12 Sep 2025 (actual)
- Primary completion
- 8 Feb 2026 (actual)
- Study completion
- 8 Feb 2026 (actual)
- First posted
- 19 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this pilot study is to create, implement, and evaluate an aquatic therapy for Postural Orthostatic Tachycardia Syndrome (POTS) program feasibility and ability to improve quality of life as determined by reduced orthostatic tachycardia, reduced POTS symptoms, and improved quality of life measures.
The main questions it aims to answer are:
Does aquatic occupational therapy reduce orthostatic tachycardia and POTS symptoms? Does aquatic occupational therapy lead to higher quality of live measures for people with POTS? Is this aquatic occupational therapy program feasible for clinicians and people with POTS?
There is no comparison group for this pilot study.
Participants will complete:
An occupational Therapy evaluation before and after program completion (3 hours total) 30 minutes at home/remote 30 minutes on-site/in-person 30 minutes of individualized occupational therapy on land
Participate in 3 aquatic therapy sessions per week, 60 minutes each for 12 weeks
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Aquatic Occupational Therapy Intervention | Experimental | Other: Aquatic Occupational TherapyAll participants will participate in the aquatic occupational therapy arm. The aquatic occupational therapy intervention is divided into three progressive months: Month 1: Breathing techniques, proprioception, balance, and vestibular activities. Easy breathing and balancing moves Example: Belly breathing, water walking, toe lifts, mountain aqua yoga pose Month 2: Strength and endurance training Building strength and ability to exercise longer Example: Water marching, core exercises using dumbbells or paddles Month 3: Advanced strengthening and endurance tasks with integrated cognitive, balance, and dual-task challenges. Harder exercises and doing two things at once, like thinking and moving together Example: Dumbbell exercises while playing a word association game |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Diagnosed with POTS, Age 18-64, Participants must be English speaking, participants must obtain a physician permission letter* * The physician letter will only state that the participant is cleared to participate in aquatic therapy, it will not confirm or state what disease the individual has in the medical records or other HIPAA information.
Key exclusion criteria (6 listed)
- Not diagnosed with POTS, Not between the ages of 18-64*, Epilepsym Bowel incontinence
- under 18 have different diagnostic criteria and mechanisms for POTS than the age range specified and may respond differently to treatment
- over age 65 have different mechanisms behind POTS than younger individuals, and frequently have health conditions or factors that can be difficult to differentiate from POTS symptoms/diagnosis and would require lab work and continuous physician involvement. POTS is less common in older adults.
- The typical age of onset for POTS is generally considered to be between the ages of 15-50 years of age
- For participant's safety, the researcher needs to be able to communicate with them in the aquatic setting. English is the researcher's only language and electronic translators are not accessible/usable in the pool setting.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Aquatic Occupational TherapyAquatic Occupational Therapy sessions will be 60 minutes long, with 45 minutes spent in the pool. Sessions will include a gentle floating, stretching, or aqua yoga warm-up and an ai chi cooldown. Exercises in the first month will include a focus on balance, breathing, and sensory work. Exercises in the second month will focus on building strength and endurance, while the third month will combine all of the above with dual-task completion. Activities will be graded down (made less difficult) or graded up (made more challenging) according to individual participant needs. | Other | Aquatic Occupational Therapy Intervention |
Primary outcome
World Health Organization Quality of Life - Brief (WHOQOL-BREF)
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
The WHOQOL-BREF is a 26-item questionnaire that will be completed digitally. It is scored by first assigning numerical values (1-5) to each response, with higher scores generally indicating a better quality of life. Then, raw domain scores are calculated by averaging the responses within each domain (Physical, Psychological, Social, and Environmental). Finally, these raw domain scores are transformed into scaled scores ranging from 0 to 100 by multiplying by 4. Higher scores on the 0-100 scale indicate a higher quality of life. The measure will be reported as a quality of life score.
The DePaul Symptom Questionnaire (Short Form) (DSQ-SF)
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention.
14-item-questionnaire which measures post-exertional malaise symptoms over the last 6 months. Each question requires two ratings, one for frequency (0 = none of the time and 4 = all of the time) and one for severity (0 = symptom not present and 4 = very severe). A frequency of at least 2 and a severity of at least 2 on any one of the 5 questions on the DSQ-SF subscale indicate that post exertional malaise is present. For each symptom, the frequency and severity scores are averaged, and then multiplied by 25 to create a composite score out of 100. The measure will be reported as a post exertional malaise score.
Composite Autonomic Symptom Score-31
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention.
Measures neurodegenerative system symptoms through 31 patient-reported questions. Assessment is through six weighted domains: orthostatic intolerance [10 points]; vasomotor [6 points]; secretomotor [7 points]; gastrointestinal [28 points]; bladder [9 points] and pupillomotor [15 points]. A higher score indicates worse autonomic dysfunction. Simple yes or no questions are scored as 0 points for no and 1 point for yes. Questions about a specific site of symptoms or symptoms under specific circumstances are scored as 0 if not present and as 1 if present for each site or circumstance. All questions regarding the frequency of symptoms were scored as 0 points for rarely or never, 1 point for occasionally or sometimes, 2 points for frequently or "a lot of the time," and 3 points for almost always or constantly. All questions regarding the severity of symptoms were scored as 1 point for mild, 2 points for moderate, and 3 points for severe. The measure will be reported as a COMPASS score
Malmo POTS Scale (MAPS)
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
This 12-item questionnaire assesses the specific POTS symptom burden over the past 3 months. Each question uses a visual analog scale from 0-10, with a maximum score of 120. A score of 42 or higher is considered indicative of POTS. The measure will be reported as a MAPS score.
ADLS, IADLS, and Vestibular Questionnaire
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
This is a 26-item questionnaire that will be filled out digitally. 21 questions cover about to participate in occupations listed in the Occupational Therapy Practice Framework using a scale from 1-10, where 1 is unable to complete the task, 5 is able to complete task with moderate difficulty (noticeable symptoms and extra effort is required) 10 is no problems/symptoms completing the task. It also contains 5 vestibular related questions using a scale from 1-7, with 1 being not at all dizzy, 4 being moderately dizzy, and 7 being extremely dizzy. The measure will be reported as an AIVQ score.
Active Stand Test
Time frame: From enrollment until the end of treatment at 12 weeks
The patient will begin laying down in a relaxed and comfortable position. Blood pressure (BP) and heart rate (HR) are taken after 5 minutes. Next, the patient will be asked to stand promptly, and will have their BP and HR measured immediately. The therapist will note any comments like "feeling dizzy". The BP and HR will be taken again and documented after three minutes, and again after ten minutes of standing. If there is any event, such as severe dizziness, paleness, etc, the BP and HR will be taken and documented just before the patient sits down. The measure will be reported as the position, time, and the correlated heart rate and blood pressure.
Single leg stance test
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
This test measures a person's ability to balance standing on one leg without assistance. The participant will stand on one leg with their hands on their hips while being timed. The test is repeated 3 times for each leg and averaged. The measure will be reported as time standing per leg.
Heart Rate
Time frame: From enrollment to the end of treatment at 12 weeks
Heart rate (HR) will be measured on land while the participant is laying down, sitting up, and standing. HR in the water will be taken while seated and standing. An aquatic HR maximum and HR zones will be calculated for each participant. This measure will be reported as a land-based and aquatic HR maximum.
Borg's rate of perceived exertion scale
Time frame: From enrollment to the end of treatment at 12 weeks
This scale is used to tell how tiring an activity feels. The scale ranges from 6 (no exertion at all), to 20 (maximal heaviness). This will be reported as the RPE score.
11 secondary outcomes
The Stroop Test
Time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention
Trail Making Test Parts A & B
Time frame: From enrollment to the end of the intervention at 12 weeks
Enrollment
Time frame: From enrollment to the end of treatment at 12 weeks
Attrition Rate
Time frame: From enrollment to the end of treatment at 12 weeks
Session attendance rate
Time frame: From enrollment to the end of treatment at 12 weeks
Cost analysis
Time frame: From enrollment to the end of treatment at 12 weeks
Health utilization changes
Time frame: From enrollment to the end of treatment at 12 weeks
Satisfaction Analysis
Time frame: From enrollment to the end of treatment at 12 weeks
Exercise self-efficacy
Time frame: From enrollment to the end of treatment at 12 weeks
Goal Attainment Scaling
Time frame: From enrollment to the end of treatment at 12 weeks
Beighton Score
Time frame: From enrollment to the end of treatment at 12 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Apr 2026.
- Individual participant dataSharing planned: No. The final dataset will include individual-level vaccination and demographic data, as well as other health characteristics. We will make the data and associated documentation available to users only under a data-sharing agreement that provides for: (1) a commitment to using the data only for research purposes and not to identify any individual participant; (2) a commitment to securing the data using appropriate computer technology; and (3) a commitment to destroying or returning the data after analyses are completed. We will share the final dataset under our own auspices and by our own determination based on review of a detailed research plan submitted by the requestor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
EvaRose Celeste, OT Doctoral student principal investigator
California State University, Dominguez Hills
Tracy Becerra-Culqui, PhD, MPH, BS OT study chair
California State University, Dominguez Hills
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Aquatic Occupational Therapy in people with Postural Orthostatic Tachycardia Syndrome (POTS), run by California State University, Dominguez Hills at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
World Health Organization Quality of Life - Brief (WHOQOL-BREF) (time frame: From enrollment to the end of 12 weeks of aquatic occupational therapy intervention). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Apr 2026.