Post Mastectomy ComplicationsNCT07181980
Intercostal Mulligan Moblization Post Mastectomy
A study testing Intercostal mulligan mobilization with shoulder abduction and Exercise in people with Post Mastectomy Complications, run by Cairo University at 1 site in Egypt.
Trial summary
the study is to evaluate the therapeutic efficacy of intercostal mulligan Mobilization in decreasing pain and improve ROM for shoulder dysfunction Patients post mastectomy. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Post Mastectomy Complications
- What is being tested?
- Intercostal mulligan mobilization with shoulder abduction and Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 16 Sep 2025to 16 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients post modified radical mastectomy at least 3 months prior and had a limited ROM in abduction.
- Patients post mastectomy with lateral chest wall pain.
- Age ranges between 40-60 years.
- All patients had informed written consent
Who cannot join
- Receiving any previous rehabilitation programs for the upper extremities
- The presence of any type of metastases
- The presence of lymphedema
- Bilateral breast cancer surgery
- Locoregional recurrence
- Withdrawal of the consent at any time during the study for any reason
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Amany R lecturer of physical therapy Cairo university, PHD physical therapy contact
Wafaa H professor in physical therapy, PHD n physical therapy contact
About this study
Official title: Effect of Intercostal Mulligan Moblization on Shoulder Dysfunction Post Mastectomy
the study is to evaluate the therapeutic efficacy of intercostal mulligan Mobilization in decreasing pain and improve ROM for shoulder dysfunction Patients post mastectomy.
- Conditions
- Post Mastectomy Complications
- Being tested
- Intercostal mulligan mobilization with shoulder abduction, Exercise
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Intercostal mulligan mobilization with shoulder abductionOther
Intercostal mulligan mobilization with shoulder abduction: is mulligain technique where the patient was Side lying with affected side up and the therapist Therapist placed ulnar side of his hand along the intercostal space of affected rib in oblique direction on the patient's wall of chest. Therapist's other hand hold the patient's elevated arm close to his abdomen 3sets 10 reptations
- Assistive range of motion exercises (AAROME): Two sets of 15 repetitions of each exercise were performed for AAROME .
- Active stretching: Two sets of 10 repetitions with 15- sec hold and relax times were performed for active stretching.
- Strengthening exercises for the shoulder joint: Two sets of 15 repetitions of each exercise .
- Postural correction exercises: 3 sets of postural correction were performed with 3-5 repetitions per set.
- Scapular strengthening exercises : two sets of ten repetitions
- The Intervention protocol: 45 to 50 minutes sessions 3 days per week for 8 week
ExerciseOther
1.3.b. Therapeutic Exercise:
- Therapeutic exercise included: (prior to 3 month post mastectomy).
- Assistive range of motion exercises (AAROME): Two sets of 15 repetitions of each exercise were performed for AAROME .
- Active stretching: Two sets of 10 repetitions with 15- sec hold and relax times were performed for active stretching. .
- Strengthening exercises for the shoulder joint: Two sets of 15 repetitions of each exercise .
- Postural correction exercises: 3 sets of postural correction were performed with 3-5 repetitions per set. .
- Scapular strengthening exercises : Strengthening exercises performed using weights were initiated with two sets of ten repetitions, beginning with a weight of 0.5kg and progressed to 0.75 and then 1 kg.
- The Intervention protocol: 45 to 50 minutes sessions 3 days per week for 8 week
| Study group | Role | What they receive |
|---|---|---|
| intercostal mulligan moblization | Active comparator | Not described Receives: Other: Intercostal mulligan mobilization with shoulder abduction; Other: Exercise |
| control group | Active comparator | Not described Receives: Other: Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
range of motion of shoulder abducation Universal goniometer.
Measured: Universal goniometer: maximum pain free shoulder abduction was investigated in an upright position .Normal range of active movement of the shoulder 180 degree Were recorded at baseline and at the end of 8 weeks of treatment.
Secondary outcomes (1)
1.4.a. Measuring shoulder function The Arabic version of DASH questionnaire
Measured: The DASH was adapted into Arabic . contains 30 items , each item has five response choices that range from 1, ''without any difficulty or no symptoms exist'' to 5, ''.Were recorded at baseline and at the end of 8 weeks of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2025
- Study start16 Sep 2025 (estimated)
- Primary completion16 Sep 2026 (estimated)
- Study completion16 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Post Mastectomy ComplicationsStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Aya Medhat Nagib Abd Elhakim, Cairo University
- Investigators
- Aya M Submitted In Partial Fulfilment of The Requirements For Master, B.Sc. of physical therapy, Principal investigator, Cairo universty
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07181980
- Sponsor's protocol ID
- P.T.REC/012/005413
- Status last verified
- Sep 2025
- First submitted
- 26 Aug 2025
- Last updated
- 19 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Salati SA, Alsulaim L, Alharbi MH, Alharbi NH, Alsenaid TM, Alaodah SA, Alsuhaibani AS, Albaqami KA. Postmastectomy Pain Syndrome: A Narrative Review. Cureus. 2023 Oct 20;15(10):e47384. doi: 10.7759/cureus.47384. eCollection 2023 Oct.
PubMed 38021812Min J, Yeon S, Ryu J, Kim JY, Yang EJ, Il Kim S, Park S, Jeon JY. Shoulder function and health outcomes in newly diagnosed breast cancer patients receiving surgery: a prospective study. Clin Breast Cancer. 2023 Jun;23(4):e247-e258. doi: 10.1016/j.clbc.2023.03.001. Epub 2023 Mar 6.
PubMed 36990840
Study at a glance
From the registry record, last updated by the sponsor on 19 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Intercostal Mulligan Moblization on Shoulder Dysfunction Post Mastectomy
- ClinicalTrials.gov ID
- NCT07181980
- Acronym / sponsor ID
- P.T.REC/012/005413
- Conditions
- Post Mastectomy Complications
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 16 Sep 2025 (estimated)
- Primary completion
- 16 Sep 2026 (estimated)
- Study completion
- 16 Sep 2026 (estimated)
- First posted
- 19 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
the study is to evaluate the therapeutic efficacy of intercostal mulligan Mobilization in decreasing pain and improve ROM for shoulder dysfunction Patients post mastectomy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intercostal mulligan moblization | Active comparator | Other: Intercostal mulligan mobilization with shoulder abduction, Other: Exercise |
| control group | Active comparator | Other: Exercise |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Patients post modified radical mastectomy at least 3 months prior and had a limited ROM in abduction.
- Patients post mastectomy with lateral chest wall pain.
- Age ranges between 40-60 years.
- All patients had informed written consent
Key exclusion criteria (6 listed)
- Receiving any previous rehabilitation programs for the upper extremities
- The presence of any type of metastases
- The presence of lymphedema
- Bilateral breast cancer surgery
- Locoregional recurrence
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Intercostal mulligan mobilization with shoulder abductionIntercostal mulligan mobilization with shoulder abduction: is mulligain technique where the patient was Side lying with affected side up and the therapist Therapist placed ulnar side of his hand along the intercostal space of affected rib in oblique direction on the patient's wall of chest. Therapist's other hand hold the patient's elevated arm close to his abdomen 3sets 10 reptations * Assistive range of motion exercises (AAROME): Two sets of 15 repetitions of each exercise were performed for AAROME . * Active stretching: Two sets of 10 repetitions with 15- sec hold and relax times were performed for active stretching. * Strengthening exercises for the shoulder joint: Two sets of 15 repetitions of each exercise . * Postural correction exercises: 3 sets of postural correction were performed with 3-5 repetitions per set. * Scapular strengthening exercises : two sets of ten repetitions * The Intervention protocol: 45 to 50 minutes sessions 3 days per week for 8 week | Other | intercostal mulligan moblization |
| Exercise1.3.b. Therapeutic Exercise: * Therapeutic exercise included: (prior to 3 month post mastectomy). * Assistive range of motion exercises (AAROME): Two sets of 15 repetitions of each exercise were performed for AAROME . * Active stretching: Two sets of 10 repetitions with 15- sec hold and relax times were performed for active stretching. . * Strengthening exercises for the shoulder joint: Two sets of 15 repetitions of each exercise . * Postural correction exercises: 3 sets of postural correction were performed with 3-5 repetitions per set. . * Scapular strengthening exercises : Strengthening exercises performed using weights were initiated with two sets of ten repetitions, beginning with a weight of 0.5kg and progressed to 0.75 and then 1 kg. * The Intervention protocol: 45 to 50 minutes sessions 3 days per week for 8 week | Other | control group, intercostal mulligan moblization |
Primary outcome
range of motion of shoulder abducation Universal goniometer.
Time frame: Universal goniometer: maximum pain free shoulder abduction was investigated in an upright position .Normal range of active movement of the shoulder 180 degree Were recorded at baseline and at the end of 8 weeks of treatment.
1 secondary outcome
1.4.a. Measuring shoulder function The Arabic version of DASH questionnaire
Time frame: The DASH was adapted into Arabic . contains 30 items , each item has five response choices that range from 1, ''without any difficulty or no symptoms exist'' to 5, ''.Were recorded at baseline and at the end of 8 weeks of treatment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Sep 2025.
- Results publication: PubMed 38021812Salati SA, Alsulaim L, Alharbi MH, Alharbi NH, Alsenaid TM, Alaodah SA, Alsuhaibani AS, Albaqami KA. Postmastectomy Pain Syndrome: A Narrative Review. Cureus. 2023 Oct 20;15(10):e47384. doi: 10.7759/cureus.47384. eCollection 2023 Oct.
- Results publication: PubMed 36990840Min J, Yeon S, Ryu J, Kim JY, Yang EJ, Il Kim S, Park S, Jeon JY. Shoulder function and health outcomes in newly diagnosed breast cancer patients receiving surgery: a prospective study. Clin Breast Cancer. 2023 Jun;23(4):e247-e258. doi: 10.1016/j.clbc.2023.03.001. Epub 2023 Mar 6.
- Individual participant dataSharing planned: No
Related trials for Post Mastectomy Complications
Not yet recruiting
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Not yet recruiting
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
Breast Cancer, Post Operative Pain
Active, not recruitingPhase 3
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Post-mastectomy Pain Syndrome, Breast Cancer
Recruiting
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
Post Mastectomy Lymphedema
Recruiting
Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy
Breast Cancer, Postoperative Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Amany R lecturer of physical therapy Cairo university, PHD physical therapy contact
Wafaa H professor in physical therapy, PHD n physical therapy contact
Aya M Submitted In Partial Fulfilment of The Requirements For Master, B.Sc. of physical therapy principal investigator
Cairo universty
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Intercostal mulligan mobilization with shoulder abduction and Exercise in people with Post Mastectomy Complications, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Amany R lecturer of physical therapy Cairo university, PHD physical therapy (+201018965528, Amany.reffat.ar@cu.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
range of motion of shoulder abducation Universal goniometer. (time frame: Universal goniometer: maximum pain free shoulder abduction was investigated in an upright position .Normal range of active movement of the shoulder 180 degree Were recorded at baseline and at the end of 8 weeks of treatment.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07181980, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Sep 2025.