Early Diagnosis of Acute Kidney InjuryNCT07181174
Early Prediction and Diagnosis of Acute Kidney Injury
An observational study of Early Diagnosis of Acute Kidney Injury, run by Aswan University at 1 site in Egypt.
Trial summary
The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke. the main questions it aims to answer are : Early detection of acute kidney injury in patient with hemorrhagic stroke . Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Early Diagnosis of Acute Kidney Injury
- What is being tested?
- Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.
- Type of treatment
- Medical device
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Dec 2024to 1 Jan 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: patients with hemorrhagic stroke
Who may be able to join
- All patients with hemorrhagic stroke presented to Aswan university hospital that will be fulfilled the following characters:
- Age >18 years.
- Both sex.
- Cases of spontaneous onset
Who cannot join
- Age < 18
- Patients with traumatic hemorrhagic stroke.
- Patients with brain tumors.
- Patients with congenital anomalies of cerebral vessels e.g. AVM (arteriovenous malformation) and cerebral aneurysm.
- Patients with history of any renal diseases
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Renal Resistive Index as a Predictor of Acute Kidney Injury in Patient With Hemorrhagic Stroke
The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke. the main questions it aims to answer are :
- Early detection of acute kidney injury in patient with hemorrhagic stroke .
- Decrease morbidity and mortality rate in patients with hemorrhagic stroke .
- Conditions
- Early Diagnosis of Acute Kidney Injury
- Being tested
- Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.Device
-Renal Resistive Index Measurement Method: Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer. First, the kidney is localised in the flanks with conventional B-mode ultrasonography, after which, color doppler images are acquired. The interlobar arteries were visualised, with the wavelength obtained by creating a 90-degree right-angle with the interlobar artery using a power doppler. After the manual determination of the peak systolic and end-diastolic velocities * RRI will be calculated by the device using the formula: RRI = (peak systolic velocity - end-diastolic velocity) / (peak systolic velocity). RRI will be measured three times for each kidney and averaged
What is being measured
The primary outcome is the main question the study is designed to answer.
Early detection of acute kidney injury in patient with hemorrhagic stroke
Measured: within 2 days and 1 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Sep 2025
- Study start1 Dec 2024
- Primary completion1 Dec 2025 (estimated)
- Study completion1 Jan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Early Diagnosis of Acute Kidney InjuryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Aswan University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Peter Essa, Aswan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07181174
- Sponsor's protocol ID
- 1016/11/24
- Status last verified
- Aug 2025
- First submitted
- 12 Sep 2025
- Last updated
- 18 Sep 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Renal Resistive Index as a Predictor of Acute Kidney Injury in Patient With Hemorrhagic Stroke
- ClinicalTrials.gov ID
- NCT07181174
- Acronym / sponsor ID
- 1016/11/24
- Conditions
- Early Diagnosis of Acute Kidney Injury
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Aswan UniversityUniversity, hospital or other
- Study start
- 1 Dec 2024 (actual)
- Primary completion
- 1 Dec 2025 (estimated)
- Study completion
- 1 Jan 2026 (estimated)
- First posted
- 18 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke. the main questions it aims to answer are :
- Early detection of acute kidney injury in patient with hemorrhagic stroke .
- Decrease morbidity and mortality rate in patients with hemorrhagic stroke .
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- patients with hemorrhagic stroke
Key inclusion criteria (4 listed)
- All patients with hemorrhagic stroke presented to Aswan university hospital that will be fulfilled the following characters:
- Age >18 years.
- Both sex.
- Cases of spontaneous onset
Key exclusion criteria (5 listed)
- Age < 18
- Patients with traumatic hemorrhagic stroke.
- Patients with brain tumors.
- Patients with congenital anomalies of cerebral vessels e.g. AVM (arteriovenous malformation) and cerebral aneurysm.
- Patients with history of any renal diseases
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.-Renal Resistive Index Measurement Method: Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer. First, the kidney is localised in the flanks with conventional B-mode ultrasonography, after which, color doppler images are acquired. The interlobar arteries were visualised, with the wavelength obtained by creating a 90-degree right-angle with the interlobar artery using a power doppler. After the manual determination of the peak systolic and end-diastolic velocities * RRI will be calculated by the device using the formula: RRI = (peak systolic velocity - end-diastolic velocity) / (peak systolic velocity). RRI will be measured three times for each kidney and averaged | Device | – |
Primary outcome
Early detection of acute kidney injury in patient with hemorrhagic stroke
Time frame: within 2 days and 1 week
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Early Diagnosis of Acute Kidney Injury, run by Aswan University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 18 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Early detection of acute kidney injury in patient with hemorrhagic stroke (time frame: within 2 days and 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Sep 2025.