AzTrials
AzTrials

Alzheimers DiseasePhase 3TRAVELLERNCT07177352

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

A Phase 3 study of Alzheimers Disease, run by Hoffmann-La Roche at 234 sites in 15 countries.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
Search all trials

Trial summary

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies. Read more about this study

Who is it for?
Ages 50 to 90 years
Conditions the study is for
Alzheimers Disease
Could I receive a placebo?
No, everyone receives an active treatment
How many people
80,000 participants
Where
234 sitesin 15 countries
Study dates
2 Jul 2025to 31 Jul 2035
Phase
Phase 3
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 50 to 90 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)
  • Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study

Who cannot join

  • Dependency in basic activities of daily living (bADLs) due to cognitive impairment
  • Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)
  • Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD
  • History of severe, clinically significant central nervous system trauma
  • Any serious medical condition that precludes a participant's safe participation and completion of a clinical study
  • For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary

Trial locations and contacts

234 sites in 15 countries. Contact the study team or a site near you to ask about taking part.

Reference Study ID Number: WP45722 https://forpatients.roche.com/ No attachments to email below. contact

888-662-6728 (U.S. and Canada)

global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry contact

234 sites in 15 countries

United States68 sites, 68 recruiting

  • IMA Clinical Research - Albuquerque

    Albuquerque, New Mexico, 87109

    Recruiting

  • Sana Research, LLC

    Arlington, Virginia, 22205

    Recruiting

  • Grady Memorial Hospital

    Atlanta, Georgia, 30303

    Recruiting

  • JEM Research LLC

    Atlantis, Florida, 33462

    Recruiting

  • Gadolin Research, LLC

    Beaumont, Texas, 77702

    Recruiting

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233

    Recruiting

  • Adams Clinical Boston

    Boston, Massachusetts, 02116

    Recruiting

  • South Texas Research Institute - Brownsville

    Brownsville, Texas, 78520

    Recruiting

  • Ralph H. Johnson VA Medical Center

    Charleston, South Carolina, 29403

    Recruiting

  • RE:Cognition (Chicago)

    Chicago, Illinois, 60611

    Recruiting

  • Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville

    Chicago, Illinois, 60640

    Recruiting

  • K2 Medical Research-Winter Garden

    Clermont, Florida, 34711

    Recruiting

  • Alzheimer's Research and Treatment Center - Columbus

    Columbus, Georgia, 31904

    Recruiting

  • Ohio State University

    Columbus, Ohio, 43221

    Recruiting

  • Kerwin Medical Center

    Dallas, Texas, 75216

    Recruiting

  • Kerwin Research Center, LLC

    Dallas, Texas, 75231

    Recruiting

  • Accel Research Sites-NeuroStudies

    Decatur, Georgia, 30030

    Recruiting

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030

    Recruiting

  • South Texas Research Institute - Edinburg

    Edinburg, Texas, 78539

    Recruiting

  • Re:Cognition Health

    Fairfax, Virginia, 22031

    Recruiting

  • Quest Research Institute

    Farmington Hills, Michigan, 48334

    Recruiting

  • Re:Cognition Health - Fort Worth

    Fort Worth, Texas, 76104

    Recruiting

  • Center for Advanced Research & Education

    Gainesville, Georgia, 30501

    Recruiting

  • Triad Clinical Trials

    Greensboro, North Carolina, 27410

    Recruiting

  • Hawaii Pacific Neuroscience

    Honolulu, Hawaii, 96817

    Recruiting

  • Re:Cognition Health - Houston

    Houston, Texas, 77030

    Recruiting

  • Sun Valley Research Center, Inc.

    Imperial, California, 92251

    Recruiting

  • Irvine Center for Clinical Research

    Irvine, California, 92614

    Recruiting

  • Mt.Olympus Medical Research

    Katy, Texas, 77450

    Recruiting

  • Genesis Neuroscience Clinic

    Knoxville, Tennessee, 37909

    Recruiting

  • K2 Medical Research - The Villages

    Lady Lake, Florida, 32159

    Recruiting

  • Basil Clinical

    Laurelton, New York, 11413-2016

    Recruiting

  • Healthy Brain Clinic

    Long Beach, California, 90804

    Recruiting

  • Inglewood Clinicals

    Los Angeles, California, 90056

    Recruiting

  • K2 Medical Research, LLC

    Maitland, Florida, 32751

    Recruiting

  • Tandem Clinical Research, LLC

    Marrero, Louisiana, 70072

    Recruiting

  • Visionary Investigators Network- Neurology Aventura

    Miami, Florida, 33133

    Recruiting

  • K2 Medical Research - Nashville

    Nashville, Tennessee, 37204

    Recruiting

  • Yale University

    New Haven, Connecticut, 06510

    Recruiting

  • Weill Cornell Medical College

    New York, New York, 10021

    Recruiting

  • Adams Clinical Harlem

    New York, New York, 10029

    Recruiting

  • Boston Center for Memory

    Newton, Massachusetts, 02459

    Recruiting

  • Oakland Clinical

    Oakland, California, 94609

    Recruiting

  • Renstar Medical Research

    Ocala, Florida, 34470

    Recruiting

  • Charter Research - Winter Park/Orlando

    Orlando, Florida, 32803

    Recruiting

  • Conquest Research - Lake Nona

    Orlando, Florida, 32832

    Recruiting

  • Banner Alzheimer?s Institute

    Phoenix, Arizona, 85006

    Recruiting

  • Flourish Research ? Philadelphia

    Plymouth Meeting, Pennsylvania, 19462

    Recruiting

  • Summit Research Network Inc.

    Portland, Oregon, 97210

    Recruiting

  • Butler Hospital

    Providence, Rhode Island, 02906

    Recruiting

  • National Clinical Research Inc.-Richmond

    Richmond, Virginia, 23294

    Recruiting

  • The Cognitive and Research Center of New Jersey

    Ridgewood, New Jersey, 07450

    Recruiting

  • El Faro Health and Therapeutics

    Rio Grande City, Texas, 78582

    Recruiting

  • Riverside Clinical

    Riverside, California, 92506

    Recruiting

  • AD-CARE, University of Rochester Medical Center

    Rochester, New York, 14620

    Recruiting

  • Syrentis Clinical Research

    Santa Ana, California, 92705

    Recruiting

  • Cenexel California Neuroscience Research, LLC

    Sherman Oaks, California, 91403

    Recruiting

  • The Cognitive and Research Center of New Jersey

    Springfield, New Jersey, 07081

    Recruiting

  • Washington University School of MedicineClinical Translational Research Unit

    St Louis, Missouri, 63110

    Recruiting

  • Alzheimer's Research and Treatment Center

    Stuart, Florida, 34996

    Recruiting

  • Palmetto Clinical Trials

    Summerville, South Carolina, 29485

    Recruiting

  • Banner Sun Health Research Institute

    Sun City, Arizona, 85351

    Recruiting

  • Axiom Brain Health LLC

    Tampa, Florida, 34654

    Recruiting

  • Adams Clinical Bronx

    The Bronx, New York, 10461

    Recruiting

  • Charter Research - Lady Lake/The Villages

    The Villages, Florida, 32162

    Recruiting

  • Adams Clinical Watertown

    Watertown, Massachusetts, 02472

    Recruiting

  • Alzheimer?s Research and Treatment Center

    Wellington, Florida, 33414

    Recruiting

  • Conquest Research, LLC

    Winter Park, Florida, 32789

    Recruiting

Other trials in United States

Japan28 sites, 11 recruiting

  • National Center for Geriatrics and Gerontology

    Aichi, 474-8511

    Recruiting

  • Brain Attack Center Ota Memorial Hospital

    Hiroshima, 720-0825

    Active, not recruiting

  • National Hospital Organization Hiroshima-Nishi Medical Center

    Hiroshima, 739-0696

    Active, not recruiting

  • Kobe University Hospital

    Hyōgo, 650-0017

    Recruiting

  • Kagawa University Hospital

    Kagawa, 761-0793

    Active, not recruiting

  • Yokohama City Minato Red Cross Hospital

    Kanagawa, 231-8682

    Recruiting

  • Kochi Medical School Hospital

    Kochi, 783-8505

    Active, not recruiting

  • Kyoto University Hospital

    Kyoto, 606-8507

    Active, not recruiting

  • National Hospital Organization Utano National Hospital

    Kyoto, 616-8255

    Active, not recruiting

  • Mishuku Hospital

    Meguro-Ku, 153-0051

    Active, not recruiting

  • Mie University Hospital

    Mie, 514-8507

    Active, not recruiting

  • Okayama City Hospital

    Okayama, 700-8557

    Active, not recruiting

  • Rijikai Medical Corporation Katayama Medical Clinic

    Okayama, 710-0813

    Active, not recruiting

  • IWATA Neurosurgery Clinic

    Osaka, 536-0007

    Recruiting

  • Kotobuki Social Medical Corporation Tominaga Clinic

    Osaka, 556-0015

    Active, not recruiting

  • Medical Corporation Heishinkai OCROM Clinic

    Osaka, 565-0853

    Recruiting

  • Medical Corporation Asbo Tokyo Asbo Clinic

    Tokyo, 104-0031

    Recruiting

  • Memory Clinic Ochanomizu

    Tokyo, 113-0034

    Active, not recruiting

  • The University of Tokyo Hospital

    Tokyo, 113-8655

    Recruiting

  • Clinical Research Hospital Tokyo

    Tokyo, 160-0004

    Recruiting

  • Tokyo Medical University Hospital

    Tokyo, 160-0023

    Recruiting

  • Keio University Hospital

    Tokyo, 160-8582

    Active, not recruiting

  • Higashi-Shinjuku Clinic

    Tokyo, 169-0072

    Recruiting

  • Tokyo Metropolitan Institute for Geriatrics and Gerontology

    Tokyo, 173-0015

    Recruiting

  • National Center of Neurology and Psychiatry

    Tokyo, 187-8551

    Active, not recruiting

  • Federation of National Public Service Personnel Mutual Aid Associations Tachikawa Hospital

    Tokyo, 190-8531

    Active, not recruiting

  • P-One Clinic

    Tokyo, 192-0071

    Active, not recruiting

  • Yamagata Tokusyukai Hospital

    Yamagata, 990-0834

    Active, not recruiting

Other trials in Japan

Poland21 sites

  • Uniwersytet Medyczny w Lodzi

    ?ód?, 92-216

    Active, not recruiting

  • ProNeuro Centrum Medyczne

    ?ory, 44-240

    Active, not recruiting

  • Syberka-ClinHouse Sp. z o.o.

    B?dzin, 42-500

    Active, not recruiting

  • Podlaskie Centrum Psychogeriatrii

    Bia?ystok, 15-756

    Active, not recruiting

  • Centrum Medyczne Neuromed Sp. z.o.o.

    Bydgoszcz, 85-163

    Active, not recruiting

  • Centrum Badan Klinicznych PI-House sp. z o.o.

    Gda?sk, 80-546

    Active, not recruiting

  • Uniwersyteckie Centrum Kliniczne;Klinika Neurologii Doros?ych

    Gdansk, 80-214

    Active, not recruiting

  • Neuro-Care Gabriela Klodowska

    Katowice, 40-749

    Active, not recruiting

  • Szpital Uniwersytecki w Krakowie

    Krakow, 30-688

    Active, not recruiting

  • Krakowska Akademia Neurologii Sp z o.o. Centrum Neurologii K

    Krakow, 31-505

    Active, not recruiting

  • Indywidualna Praktyka Lekarska Prof. Dr Hab. N. Med. Konrad Rejdak.

    Lublin, 20-410

    Active, not recruiting

  • Clinical Research Center Sp. z o.o. MEDIC-R Spó?ka Komandytowa

    Późna, 61-731

    Active, not recruiting

  • Nmedis sp. z o.o.

    Rzeszów, 35-323

    Active, not recruiting

  • Centrum Medyczne Medyk

    Rzeszów, 35-326

    Active, not recruiting

  • O?rodek Badawczo-Naukowo-Dydaktyczny Chorób Ot?piennych w ?cinawie

    Ścinawa, 59-330

    Active, not recruiting

  • Senior Sp. Z O.O. Poradnia Psychogeriatryczna

    Sopot, 81-855

    Active, not recruiting

  • Centrum Medyczne NeuroProtect

    Warsaw, 01-684

    Active, not recruiting

  • ETG Neuroscience Sp. z o.o.

    Warsaw, 02-677

    Active, not recruiting

  • Centrum Leczenia Zaburzen Pamieci

    Warsaw, 03-839

    Active, not recruiting

  • NZOZ WCA

    Wroc?aw, 53-659

    Active, not recruiting

  • Samodzielny Publiczny Szpital Kliniczny Nr 1 im. Prof. Stanislawa SzyszkoSUM w Katowicach

    Zabrze, 41-800

    Active, not recruiting

Other trials in Poland

Canada17 sites, 16 recruiting

  • True North Clinical Research-Halifax

    Halifax, Nova Scotia, B3S 1N2

    Recruiting

  • Okanagan Clinical Trials

    Kelowna, British Columbia, V1Y 1Z9

    Recruiting

  • Kelowna Health and Memory Centre Ltd.

    Kelowna, British Columbia, V1Y 5A8

    Recruiting

  • Parkwood Institute, Mental Health Care Building

    London, Ontario, N6C 0A7

    Recruiting

  • Clinique Memoire de Montreal

    Montreal, Quebec, H2X 3B9

    Recruiting

  • Genge Partners Inc.

    Montreal, Quebec, H4A 3T2

    Recruiting

  • Bruyère Health Research Institute

    Ottawa, Ontario, K1N 5C8

    Recruiting

  • The Ottawa Memory Clinic

    Ottawa, Ontario, K1Z 1G3

    Recruiting

  • Kawartha Regional Memory Clinic

    Peterborough, Ontario, K9H 2P4

    Recruiting

  • Alpha Recherche Clinique

    Québec, G3K 2P8

    Recruiting

  • Richmond Clinical Trials

    Richmond, British Columbia, V6V 2L1

    Recruiting

  • Toronto Memory Program

    Toronto, Ontario, M3B 2S7

    Recruiting

  • Centricity East York

    Toronto, Ontario, M4G 3E8

    Recruiting

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5

    Recruiting

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8

    Active, not recruiting

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8

    Recruiting

  • Baycrest Health Sciences

    Toronto, Ontario, M6A 2E1

    Recruiting

Other trials in Canada

China16 sites, 16 recruiting

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034

    Recruiting

  • Beijing Friendship Hospital Affiliated of Capital University of Medical Science

    Beijing, 100050

    Recruiting

  • The First Hospital of Jilin University

    Changchun, 130021

    Recruiting

  • West China Hospital - Sichuan University

    Chengdu, 610047

    Recruiting

  • The First Affiliated Hospital, Chongqing Medical University

    Chongqing, 400016

    Recruiting

  • The second Affiliated Hospital of Guangzhou Medical University

    Guangzhou, 510000

    Recruiting

  • Guangdong General Hospital

    Guangzhou, 510080

    Recruiting

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, 230022

    Recruiting

  • Zhongda Hospital Affiliated to Southeast University

    Nanjing, 210009

    Recruiting

  • Nanjing Brain Hospital

    Nanjing, 210029

    Recruiting

  • Nanjing First Hospital

    Nanjing, 210029

    Recruiting

  • Huashan Hospital, Fudan University

    Shanghai, 200040

    Recruiting

  • Shanghai First People's Hospital

    Shanghai, 200080

    Recruiting

  • Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    Shanghai, 200127

    Recruiting

  • The Second Affiliated Hospital of Soochow University

    Suzhou, 215004

    Recruiting

  • The Affiliated Hospital of Xuzhou Medical University

    Xuzhou, Jiangsu, 221002

    Recruiting

Other trials in China

Spain15 sites

  • Fundación ACE

    Barcelona, 08028

    Active, not recruiting

  • Hospital Vall d'Hebron

    Barcelona, 08035

    Active, not recruiting

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041

    Active, not recruiting

  • Hospital Universitario Reina Sofia

    Córdoba, 14011

    Active, not recruiting

  • Hospital de Dénia;Servicio de Neurología

    Denia, Alicante, 03700

    Active, not recruiting

  • Policlínica Guipuzkoa

    Donosti-San Sebastián, 20014

    Active, not recruiting

  • Hospital San Cecilio

    Granada, 18016

    Active, not recruiting

  • Hospital Universitario de la Princesa

    Madrid, 28006

    Active, not recruiting

  • Hospital Universitario 12 de Octubre

    Madrid, 28041

    Active, not recruiting

  • Fundació Hospitalàries Martorell;Neurology

    Martorell, Barcelona, 08760

    Active, not recruiting

  • Hospital Quiron de Madrid

    Pozuelo de Alarcón, Madrid, 28223

    Active, not recruiting

  • Hospital Virgen del Rocío

    Seville, 41013

    Active, not recruiting

  • Hospital Mutua De Terrasa

    Terrassa, Barcelona, 08221

    Active, not recruiting

  • Hospital Universitario Dr. Peset

    Valencia, 46017

    Active, not recruiting

  • Hospital Universitario la Fe

    Valencia, 46026

    Active, not recruiting

Other trials in Spain

South Korea13 sites, 12 recruiting

  • Chonnam National University Hospital

    Gwangju, 61469

    Recruiting

  • St. Vincent's Hospital

    Gyeonggi-do, 442-723

    Active, not recruiting

  • Inha University Hospital

    Incheon, 22332

    Recruiting

  • Gachon University Gil Medical Center

    Namdong-gu, 21565

    Recruiting

  • Seoul National University Bundang Hospital

    Seongnam-si, 13605

    Recruiting

  • Hanyang University Seoul Hospital

    Seoul, 04763

    Recruiting

  • Konkuk University Medical Center

    Seoul, 05030

    Recruiting

  • Gangnam Severance Hospital

    Seoul, 06273

    Recruiting

  • Samsung Medical Center

    Seoul, 06351

    Recruiting

  • Ewha Womans University Hospital (Seoul)

    Seoul, 07804

    Recruiting

  • Korea University Guro Hospital

    Seoul, 08308

    Recruiting

  • Asan Medical Center

    Seoul, DUMMY_VALUE

    Recruiting

  • Ajou University Medical Center

    Suwon, 16499

    Recruiting

Other trials in South Korea

Australia10 sites, 10 recruiting

  • Flinders Medical Centre

    Bedford Park, South Australia, 5042

    Recruiting

  • Box Hill Hospital

    Box Hill, Victoria, 3128

    Recruiting

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050

    Recruiting

  • St Vincent's Hospital Sydney

    Darlinghurst, New South Wales, 2010

    Recruiting

  • Heidelberg Repatriation Hospital

    Heidelberg, Victoria, 3081

    Recruiting

  • Southern Neurology

    Kogarah, New South Wales, 2217

    Recruiting

  • KaRa Institute of Neurological Diseases

    Macquarie Park, New South Wales, 2113

    Recruiting

  • Alfred Health

    Melbourne, Victoria, 3004

    Recruiting

  • Royal Melbourne Hospital

    Parkville, Victoria, 3050

    Recruiting

  • Queen Elizabeth Hospital

    Woodville, South Australia, 5011

    Recruiting

Other trials in Australia

Italy10 sites

  • Asst Degli Spedali Civili Di Brescia

    Brescia, Lombardy, 25100

    Active, not recruiting

  • Irccs A.O.U.San Martino Ist

    Genoa, Liguria, 16132

    Active, not recruiting

  • IRCCS Ospedale San Raffaele

    Milan, Lombardy, 20132

    Active, not recruiting

  • A. O. U. Federico II

    Naples, Campania, 80131

    Active, not recruiting

  • AOU Policlinico Giaccone

    Palermo, Sicily, 90129

    Active, not recruiting

  • AO di Perugia - Ospedale S. Maria della Misericordia

    Perugia, Umbria, 06156

    Active, not recruiting

  • Policlinico Universitario Agostino Gemelli

    Rome, Lazio, 00168

    Active, not recruiting

  • Fondazione Santa Lucia IRCCS

    Rome, Lazio, 00179

    Active, not recruiting

  • Umberto I Policlinico di Roma-Università di Roma La Sapienza

    Rome, Lazio, 00185

    Active, not recruiting

  • Ospedale Isola Tiberina - Gemelli Isola

    Rome, Lazio, 00186

    Active, not recruiting

Other trials in Italy

Taiwan10 sites, 9 recruiting

  • Changhua Christian Hospital

    Changhua County, 500

    Recruiting

  • Kaohsiung Medical University Hospital

    Kaohsiung City, 807

    Active, not recruiting

  • Chang Gung Medical Foundation - LinKou Chang Gung Memorial Hospital - Neurology

    Kwei Shen, 33305

    Recruiting

  • Taipei Medical University - Shuang Ho Hospital - Neurology

    New Taipei City, 23561

    Recruiting

  • New Taipei Municipal TuCheng Hospital;Neurology

    New Taipei City, 236

    Recruiting

  • China Medical University Hospital

    North Dist., 40447

    Recruiting

  • Taichung Veterans General Hospital

    Taichung, 40705

    Recruiting

  • National Cheng Kung University Hospital

    Tainan, 704

    Recruiting

  • National Taiwan University Hospital

    Taipei, 100

    Recruiting

  • Taipei Veterans General Hospital-Neurology

    Taipei, 112

    Recruiting

Other trials in Taiwan

Brazil8 sites, 8 recruiting

  • Instituto de Neurologia de Curitiba

    Curitiba, Paraná, 81210-310

    Recruiting

  • Clinica Neurologica

    Joinville, Santa Catarina, 89202-190

    Recruiting

  • Clinica Clinilive ltda

    Maringá, Paraná, 87013-250

    Recruiting

  • Hospital Moinhos de Vento

    Porto Alegre, Rio Grande do Sul, 90035-001

    Recruiting

  • Hospital das Clinicas - UFRGS

    Porto Alegre, Rio Grande do Sul, 90035-903

    Recruiting

  • Instituto do Cerebro do Rio Grande do Sul

    Porto Alegre, Rio Grande do Sul, 90610-000

    Recruiting

  • Centro Multidisciplinar de Estudos Clínicos - CEMEC*X*

    São Bernardo do Campo, São Paulo, 09715-090

    Recruiting

  • Centro de Pesquisas Clinicas - CPCLIN

    São Paulo, São Paulo, 01244-030

    Recruiting

Other trials in Brazil

Chile8 sites, 8 recruiting

  • Biomedica Research Group

    Santiago, 7500710

    Recruiting

  • Icegclinic

    Santiago, 7510187

    Recruiting

  • Centro de Medicina de Precisión

    Santiago, 7560908

    Recruiting

  • Clinica Las Condes

    Santiago, 7591046

    Recruiting

  • Clinica MEDS

    Santiago, 7691236

    Recruiting

  • Centro de Investigación Clínica UC-CICUC

    Santiago, 8330034

    Recruiting

  • Hospital Clínico Universidad de Chile

    Santiago, 8380000

    Recruiting

  • Clinical Research Valdivia

    Valdivia, 5110683

    Recruiting

Other trials in Chile

Argentina6 sites, 4 recruiting

  • INECO

    Buenos Aires, 000C1021

    Recruiting

  • Hospital Italiano de Buenos Aires

    Buenos Aires, C1181ACH

    Recruiting

  • CIER

    C. A. B. A., C1055AAF

    Completed

  • Fundacion Scherbovsky

    Mendoza, 5500

    Recruiting

  • INECO Neurociencias Orono

    Rosario, Santa Fe Province, S2000DTC

    Recruiting

  • Sanatorio del Sur S.A.

    San Miguel de Tucumán, T4000IDK

    Completed

Other trials in Argentina

Denmark3 sites, 3 recruiting

  • Aalborg Universitetshospital

    Aalborg, 9000

    Recruiting

  • Aarhus Universitetshospital Skejby

    Aarhus N, 8200

    Recruiting

  • Rigshospitalet, Hukommelsesklinikken

    København Ø, 2100

    Recruiting

Other trials in Denmark

Puerto Rico1 site, 1 recruiting

  • University of Puerto Rico - Medical Science Campus

    San Juan, 00935

    Recruiting

Other trials in Puerto Rico

About this study

Official title: Master Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies as Assessed by Biomarker Status and Cognition

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

Being tested
No Intervention
Keywords
Early Alzheimers Disease, Mild Cognitive Impairment, Mild Dementia, Preclinical AD
Medical subject headings
Alzheimer Disease, Cognitive Dysfunction

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • No InterventionOther

    Participants will have their blood drawn and cognitive score measured by the ISLT.

Study groups in NCT07177352
Study groupRoleWhat they receive
Screening ArmOtherParticipants will be assessed for their concentration of pTau217 in blood and cognitive score in the International Shopping List Test (ISLT).
Receives: Other: No Intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Concentration of pTau217 in Blood on Day1

    Measured: Day 1

  2. Cognitive score in ISLT on Day 1

    Measured: Day 1

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted17 Sep 2025
  2. Study start2 Jul 2025
  3. Primary completion31 Jul 2035 (estimated)
  4. Study completion31 Jul 2035 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase 3
Primary purpose
Screening
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
80,000 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07177352
Sponsor's protocol ID
WP45722
Acronym
TRAVELLER
Status last verified
Oct 2026
First submitted
15 Sep 2025
Last updated
19 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A Phase 3 study of Alzheimers Disease, run by Hoffmann-La Roche at 234 sites in 15 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 234 sites in United States, Japan, Poland, Canada, China and 10 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

What does this phase mean?

Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.

Not every study follows the same path, and some studies (observational studies, device studies) have no phase.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Reference Study ID Number: WP45722 https://forpatients.roche.com/ No attachments to email below. (888-662-6728 (U.S. and Canada), global-roche-genentech-trials@gene.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Concentration of pTau217 in Blood on Day1 (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07177352.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.

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