Alveolar Ridge PreservationPONTIC-MPMNCT07171879
Pontic Shield and Mineralized Plasmatic Matrix for Ridge Preservation
A study testing Tooth Extraction only, Extraction + MPM and Pontic Shield Only in people with Alveolar Ridge Preservation, run by Soaad Tolba Mohammed Tolba Badawi at 1 site in Egypt.
Trial summary
This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Alveolar Ridge Preservation
- What is being tested?
- Tooth Extraction only, Extraction + MPM and Pontic Shield Only
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2024to 1 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults (≥18 years).
- Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification.
- Presence of Type 1 extraction sockets (intact buccal bone and soft tissues).
- Adequate oral hygiene.
- Sufficient inter-arch space for prosthetic rehabilitation.
- Willingness to comply with study protocol and follow-up schedule.
Who cannot join
- Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression).
- History of head and neck radiotherapy or bisphosphonate therapy.
- Acute infection or suppuration at the extraction site.
- Severe periodontal disease.
- Root caries or tooth mobility.
- Buccal bone plate loss due to vertical/horizontal root fractures or advanced periodontitis.
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Dentistry, Mansoura University
Al Mansurah, Dakahlia Governorate, 35511
About this study
Official title: Partial Extraction Therapy for Facial Contour Preservation, "Old is Gold or Time for Change?" A Randomized Clinical Trial
This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. A technique called Partial Extraction Therapy (Pontic Shield Technique) keeps part of the tooth root in place to help maintain the natural shape of the bone and gums. Another method, called Mineralized Plasmatic Matrix (MPM), uses a patient's own blood mixed with bone particles to support healing.
In this randomized clinical trial, 56 patients were assigned to one of four groups:
Read more
Group I: Tooth extraction only Group II: Tooth extraction with MPM grafting Group III: Pontic shield technique alone Group IV: Pontic shield technique with MPM grafting The main outcome measured was the amount of bone width preserved, using 3D X-rays (CBCT). Other outcomes included bone height and soft-tissue healing over 4 months.
This research will help determine whether the pontic shield technique, with or without MPM, provides better preservation of bone and gum tissue compared to tooth extraction alone.
- Conditions
- Alveolar Ridge Preservation
- Being tested
- Tooth Extraction only, Extraction + MPM, Pontic Shield Only, Pontic Shield + MPM
- Keywords
- Partial extraction therapy, Pontic shield, Mineralized plasmatic matrix (MPM), Socket preservation, Wound healing index
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tooth Extraction onlyProcedure or surgery
Conventional atraumatic extraction of the non-restorable maxillary tooth in the esthetic zone without socket preservation procedures.
Extraction + MPMProcedure or surgery
Tooth extraction followed by socket grafting using MPM, prepared from autologous blood combined with xenograft bone particles.
Pontic Shield OnlyProcedure or surgery
Partial extraction therapy using the pontic shield technique, in which the buccal root fragment is preserved to maintain ridge contour, without additional grafting.
Pontic Shield + MPMProcedure or surgery
Pontic shield technique combined with grafting using mineralized plasmatic matrix (MPM) for enhanced ridge preservation and healing.
| Study group | Role | What they receive |
|---|---|---|
| Extraction Only | Active comparator | Patients receive total tooth extraction in the esthetic maxillary zone without any adjunctive grafting. Receives: Procedure: Tooth Extraction only |
| Extraction + MPM | Active comparator | Patients receive total tooth extraction in the esthetic maxillary zone, followed by grafting with MPM. Receives: Procedure: Extraction + MPM |
| Pontic Shield Only | Active comparator | Patients undergo the pontic shield technique, in which a portion of the buccal root is preserved to maintain ridge contour, without grafting. Receives: Procedure: Pontic Shield Only |
| Pontic Shield + MPM | Active comparator | Patients undergo the pontic shield technique combined with MPM grafting for ridge preservation. Receives: Procedure: Pontic Shield + MPM |
What is being measured
The primary outcome is the main question the study is designed to answer.
Alveolar Ridge Width Change
Mean changes in alveolar ridge width measured at standardized reference points on cone-beam computed tomography (CBCT) Unit of Measure: millimeters (mm)
Measured: Baseline (pre- or immediate post-extraction) to 4 months.
Secondary outcomes (2)
Buccal and Palatal Bone Height Change
Change in buccal and palatal bone heights measured on CBCT from baseline to 4 months.
Unit of Measure: mm
Measured: Baseline to 4 months.
Soft-Tissue Healing (Wound Healing Index, WHI)
Clinical soft-tissue healing evaluated using the WHI. Unit of Measure: score on 5-point scale with higher values indicating more favorable wound healing.
Measured: 1 week and 4 months post-extraction.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Sep 2025
- Study start1 Sep 2024
- Primary completion1 Jul 2025
- Study completion1 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alveolar Ridge PreservationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were randomized to one of four groups: extraction alone, extraction with MPM, pontic shield alone, or pontic shield with MPM.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 56 participants (actual)
Sponsor and investigators
- Lead sponsor
- Soaad Tolba Mohammed Tolba Badawi
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Soaad Tolba Mohammed Tolba Badawi, Mansoura University
- Investigators
- Soaad Tolba Badawy, Lecturer, Oral Surgery, MU, Principal investigator, Mansoura University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07171879
- Sponsor's protocol ID
- R.25.09.22
- Acronym
- PONTIC-MPM
- Status last verified
- Sep 2025
- First submitted
- 6 Sep 2025
- Last updated
- 17 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Partial Extraction Therapy for Facial Contour Preservation, "Old is Gold or Time for Change?" A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07171879
- Acronym / sponsor ID
- PONTIC-MPM / R.25.09.22
- Conditions
- Alveolar Ridge Preservation
- Keywords
- Partial extraction therapy, Pontic shield, Mineralized plasmatic matrix (MPM), Socket preservation, Wound healing index
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 56 participants (actual)
- Lead sponsor
- Soaad Tolba Mohammed Tolba BadawiUniversity, hospital or other
- Study start
- 1 Sep 2024 (actual)
- Primary completion
- 1 Jul 2025 (actual)
- Study completion
- 1 Jul 2025 (actual)
- First posted
- 15 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. A technique called Partial Extraction Therapy (Pontic Shield Technique) keeps part of the tooth root in place to help maintain the natural shape of the bone and gums. Another method, called Mineralized Plasmatic Matrix (MPM), uses a patient's own blood mixed with bone particles to support healing.
In this randomized clinical trial, 56 patients were assigned to one of four groups:
Group I: Tooth extraction only Group II: Tooth extraction with MPM grafting Group III: Pontic shield technique alone Group IV: Pontic shield technique with MPM grafting The main outcome measured was the amount of bone width preserved, using 3D X-rays (CBCT). Other outcomes included bone height and soft-tissue healing over 4 months.
This research will help determine whether the pontic shield technique, with or without MPM, provides better preservation of bone and gum tissue compared to tooth extraction alone.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 4
- Model description
- Participants were randomized to one of four groups: extraction alone, extraction with MPM, pontic shield alone, or pontic shield with MPM.
| Arm | Type | Receives |
|---|---|---|
| Extraction Only | Active comparator | Procedure: Tooth Extraction onlyPatients receive total tooth extraction in the esthetic maxillary zone without any adjunctive grafting. |
| Extraction + MPM | Active comparator | Procedure: Extraction + MPMPatients receive total tooth extraction in the esthetic maxillary zone, followed by grafting with MPM. |
| Pontic Shield Only | Active comparator | Procedure: Pontic Shield OnlyPatients undergo the pontic shield technique, in which a portion of the buccal root is preserved to maintain ridge contour, without grafting. |
| Pontic Shield + MPM | Active comparator | Procedure: Pontic Shield + MPMPatients undergo the pontic shield technique combined with MPM grafting for ridge preservation. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Adults (≥18 years).
- Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification.
- Presence of Type 1 extraction sockets (intact buccal bone and soft tissues).
- Adequate oral hygiene.
- Sufficient inter-arch space for prosthetic rehabilitation.
Key exclusion criteria (6 listed)
- Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression).
- History of head and neck radiotherapy or bisphosphonate therapy.
- Acute infection or suppuration at the extraction site.
- Severe periodontal disease.
- Root caries or tooth mobility.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tooth Extraction onlyConventional atraumatic extraction of the non-restorable maxillary tooth in the esthetic zone without socket preservation procedures. | Procedure or surgery | Extraction Only |
| Extraction + MPMTooth extraction followed by socket grafting using MPM, prepared from autologous blood combined with xenograft bone particles. | Procedure or surgery | Extraction + MPM |
| Pontic Shield OnlyPartial extraction therapy using the pontic shield technique, in which the buccal root fragment is preserved to maintain ridge contour, without additional grafting. | Procedure or surgery | Pontic Shield Only |
| Pontic Shield + MPMPontic shield technique combined with grafting using mineralized plasmatic matrix (MPM) for enhanced ridge preservation and healing. | Procedure or surgery | Pontic Shield + MPM |
Primary outcome
Alveolar Ridge Width Change
Time frame: Baseline (pre- or immediate post-extraction) to 4 months.
Mean changes in alveolar ridge width measured at standardized reference points on cone-beam computed tomography (CBCT) Unit of Measure: millimeters (mm)
2 secondary outcomes
Buccal and Palatal Bone Height Change
Time frame: Baseline to 4 months.
Soft-Tissue Healing (Wound Healing Index, WHI)
Time frame: 1 week and 4 months post-extraction.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Soaad Tolba Badawy, Lecturer, Oral Surgery, MU principal investigator
Mansoura University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Tooth Extraction only, Extraction + MPM and Pontic Shield Only in people with Alveolar Ridge Preservation, run by Soaad Tolba Mohammed Tolba Badawi at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Alveolar Ridge Width Change (time frame: Baseline (pre- or immediate post-extraction) to 4 months.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2025.