StrabismusNCT07152964
Medial Rectus Tendon Width and Surgical Dose Response in Commitant Esotropic Patients
An observational study of Strabismus, run by Assiut University.
Trial summary
This study aims to investigate the clinical correlation between medial rectus tendon width and surgical dose response in esotropic patients undergoing medical rectus recession Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Strabismus
- What is being tested?
- Caliper
- Type of treatment
- Medical device
- How many people
- 28 participants
- Where
- No sites listed yet
- Study dates
- Sep 2025to Oct 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession
Who may be able to join
- All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession
Who cannot join
- previous extraocular muscle surgery Incomitant esotropia
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Clinical Correlation Between Medial Rectus Tendon Width and Surgical Dose Response in Commitant Esotropic Patients Undergoing Medical Rectus Recession
This study aims to investigate the clinical correlation between medial rectus tendon width and surgical dose response in esotropic patients undergoing medical rectus recession
Read the detailed description
Esotropia is a type of strabismus where one or both eyes turn inward(1).Medial rectus tendon width is horizontal thickness of the tendon of the medial rectus muscle, one of the extraocular muscles.Medial rectus recession is a standard surgical treatment for esotropia involving weakening the medial rectus muscle by repositioning it posteriorly(2).Surgical Dose Response describes how much eye alignment in prism diopters is achieved per millimeter of muscle recession.
Studies on medial rectus resection revealed that higher medial rectus tendon width (MRTW) was associated with a larger surgical dose-response(3).Other studies revealed that the effect of lateral rectus recession in patients with intermittent exotropia was larger in cases with narrower lateral rectus tendon width (4,5).
The potential impact of medial rectus tendon width on the effectiveness of medial rectus recession had not been studied.
- Conditions
- Strabismus
- Being tested
- Caliper
- Medical subject headings
- Strabismus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
CaliperDevice
Measure medial rectus tendon width with caliper intraoperative
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinical correlation between medial rectus tendon width and surgical dose response in comitant esotropic patients undergoing medial rectus recession
Can medial rectus tendon width affect surgical dose response in commitant esotropic patients undergoing medial rectus recession
Measured: Baseline
Variation in medial rectus tendon width in different age groups
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2025
- Study startSep 2025 (estimated)
- Primary completionSep 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrabismusStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 28 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Reham Yahya Abdel Mohsen AbdelHafez, Assiut University
- Investigators
- Ali Natag Riad, Professor, Study director, Assiut UniversityMohammed Anwr Sayed, Assistant professor, Study director, Assiut UniversitySara Hussein AlAttar, Assistant professor, Study director, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07152964
- Sponsor's protocol ID
- Medial rectus tendon width
- Status last verified
- Aug 2025
- First submitted
- 26 Aug 2025
- Last updated
- 3 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Correlation Between Medial Rectus Tendon Width and Surgical Dose Response in Commitant Esotropic Patients Undergoing Medical Rectus Recession
- ClinicalTrials.gov ID
- NCT07152964
- Acronym / sponsor ID
- Medial rectus tendon width
- Conditions
- Strabismus
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 28 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- Sep 2025 (estimated)
- Primary completion
- Sep 2026 (estimated)
- Study completion
- Oct 2026 (estimated)
- First posted
- 3 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the clinical correlation between medial rectus tendon width and surgical dose response in esotropic patients undergoing medical rectus recession
Detailed description
Esotropia is a type of strabismus where one or both eyes turn inward(1).Medial rectus tendon width is horizontal thickness of the tendon of the medial rectus muscle, one of the extraocular muscles.Medial rectus recession is a standard surgical treatment for esotropia involving weakening the medial rectus muscle by repositioning it posteriorly(2).Surgical Dose Response describes how much eye alignment in prism diopters is achieved per millimeter of muscle recession.
Studies on medial rectus resection revealed that higher medial rectus tendon width (MRTW) was associated with a larger surgical dose-response(3).Other studies revealed that the effect of lateral rectus recession in patients with intermittent exotropia was larger in cases with narrower lateral rectus tendon width (4,5).
The potential impact of medial rectus tendon width on the effectiveness of medial rectus recession had not been studied.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession
Key inclusion criteria (1 listed)
- All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession
Key exclusion criteria (1 listed)
- previous extraocular muscle surgery Incomitant esotropia
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| CaliperMeasure medial rectus tendon width with caliper intraoperative | Device | – |
Primary outcome
Clinical correlation between medial rectus tendon width and surgical dose response in comitant esotropic patients undergoing medial rectus recession
Time frame: Baseline
Can medial rectus tendon width affect surgical dose response in commitant esotropic patients undergoing medial rectus recession
Variation in medial rectus tendon width in different age groups
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2025.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ali Natag Riad, Professor study director
Assiut University
Mohammed Anwr Sayed, Assistant professor study director
Assiut University
Sara Hussein AlAttar, Assistant professor study director
Assiut University
Questions about this trial
What is this clinical trial studying?
An observational study of Strabismus, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Reham Yahya AbdelMohsen, Resident doctor (+201140167502, rehamyahya123456@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinical correlation between medial rectus tendon width and surgical dose response in comitant esotropic patients undergoing medial rectus recession (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2025.