Magnetic Resonance ImagingNCT07138768
Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time in Emergency Settings
An observational study of Magnetic Resonance Imaging and Diagnosis, run by Tanta University at 1 site in Egypt.
Trial summary
This study aims to evaluate the role of stroke protocol in the early diagnosis and management of acute stroke and its effect on turnaround time (TAT) in emergency settings. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Magnetic Resonance Imaging, Diagnosis, Management
- What is being tested?
- Magnetic Resonance Imaging
- Type of treatment
- Medical device
- How many people
- 136 participants
- Where
- 1 siteEgypt
- Study dates
- 23 Aug 2025to 1 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: This prospective cohort study will be carried out on 136 patients presenting with acute stroke symptoms after approval from the institutional ethical committee.
Who may be able to join
- Age ≥18 years.
- Both sexes.
- Patients with acute stroke who are admitted to the emergency department.
Who cannot join
- Contraindications to magnetic resonance imaging (MRI) or computed tomography (CT).
- Symptoms strongly suggestive of subarachnoid hemorrhage.
- Initiation of antithrombotic or thrombolytic treatment before the completion of both scans.
- Inability to complete both scans in time to allow thrombolytic treatment within three h of the onset of symptoms.
- Uncontrollable hypertension.
- Pregnant or lactating women.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Tanta University
Tanta, El-Gharbia, 31527
Hend M Mansour, MD, 00201221474344, hend.mansour@med.tanta.edu.eg
Radwa Mohamed, MD
About this study
Official title: The Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time (TAT) in Emergency Settings
This study aims to evaluate the role of stroke protocol in the early diagnosis and management of acute stroke and its effect on turnaround time (TAT) in emergency settings.
Read the detailed description
Acute stroke is a common and often devastating disorder; however, acute treatments that reduce long-term disability are available if patients present within the time window for treatment.
Computed tomography (CT) or magnetic resonance imaging (MRI) has been used in comprehensive stroke centers, although the role of advanced imaging in the improvement of stroke outcome remains controversial.
MRI offers advantages for the assessment of acute stroke. Changes of acute ischaemic injury are detectable sooner with MRI than with CT, especially with diffusion-weighted imaging, and ischaemic stroke diagnosis with MRI has greater interobserver and intraobserver reliability than CT, even in readers with little experience.
- Conditions
- Magnetic Resonance Imaging, Diagnosis, Management, Acute Stroke, Turnaround Time, Emergency Settings
- Being tested
- Magnetic Resonance Imaging
- Medical subject headings
- Disease, Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Magnetic Resonance ImagingDevice
Magnetic Resonance Imaging will be performed to all patients
| Study group | Role | What they receive |
|---|---|---|
| Study group | Patients with acute stroke who are admitted to the emergency department. Receives: Device: Magnetic Resonance Imaging |
What is being measured
The primary outcome is the main question the study is designed to answer.
Sensitivity of magnetic resonance imaging for acute stroke
Sensitivity of magnetic resonance imaging for acute stroke will be recorded.
Measured: Immediately post-procedure (Up to 1 hour)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Aug 2025
- Study start23 Aug 2025
- Primary completion1 Dec 2026 (estimated)
- Study completion1 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Magnetic Resonance ImagingStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 136 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hend Mohammed Mansour, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07138768
- Sponsor's protocol ID
- 36264PR1258/6/25
- Status last verified
- Aug 2025
- First submitted
- 17 Aug 2025
- Last updated
- 26 Aug 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time (TAT) in Emergency Settings
- ClinicalTrials.gov ID
- NCT07138768
- Acronym / sponsor ID
- 36264PR1258/6/25
- Conditions
- Magnetic Resonance Imaging, Diagnosis, Management, Acute Stroke, Turnaround Time, Emergency Settings
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 136 participants (estimated)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 23 Aug 2025 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 1 Dec 2026 (estimated)
- First posted
- 24 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the role of stroke protocol in the early diagnosis and management of acute stroke and its effect on turnaround time (TAT) in emergency settings.
Detailed description
Acute stroke is a common and often devastating disorder; however, acute treatments that reduce long-term disability are available if patients present within the time window for treatment.
Computed tomography (CT) or magnetic resonance imaging (MRI) has been used in comprehensive stroke centers, although the role of advanced imaging in the improvement of stroke outcome remains controversial.
MRI offers advantages for the assessment of acute stroke. Changes of acute ischaemic injury are detectable sooner with MRI than with CT, especially with diffusion-weighted imaging, and ischaemic stroke diagnosis with MRI has greater interobserver and intraobserver reliability than CT, even in readers with little experience.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Study group | – | Device: Magnetic Resonance ImagingPatients with acute stroke who are admitted to the emergency department. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- This prospective cohort study will be carried out on 136 patients presenting with acute stroke symptoms after approval from the institutional ethical committee.
Key inclusion criteria (3 listed)
- Age ≥18 years.
- Both sexes.
- Patients with acute stroke who are admitted to the emergency department.
Key exclusion criteria (6 listed)
- Contraindications to magnetic resonance imaging (MRI) or computed tomography (CT).
- Symptoms strongly suggestive of subarachnoid hemorrhage.
- Initiation of antithrombotic or thrombolytic treatment before the completion of both scans.
- Inability to complete both scans in time to allow thrombolytic treatment within three h of the onset of symptoms.
- Uncontrollable hypertension.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Magnetic Resonance ImagingMagnetic Resonance Imaging will be performed to all patients | Device | Study group |
Primary outcome
Sensitivity of magnetic resonance imaging for acute stroke
Time frame: Immediately post-procedure (Up to 1 hour)
Sensitivity of magnetic resonance imaging for acute stroke will be recorded.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2025.
- Individual participant dataSharing planned: Yes. The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Magnetic Resonance Imaging and Diagnosis, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hend M Mansour, MD (00201221474344, hend.mansour@med.tanta.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Sensitivity of magnetic resonance imaging for acute stroke (time frame: Immediately post-procedure (Up to 1 hour)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2025.