Breast CancerNCT07137468
Everyday Exposures: How Chemicals and Weight Impact Breast Cancer Risk
An observational study of Breast Cancer, run by M.D. Anderson Cancer Center at 1 site in United States.
Trial summary
To learn about breast cancer survivors' and their family members' knowledge of and interest in learning about environmental exposures related to personal care products. Researchers also want to learn if there is a link between excessive weight and chemicals that may affect hormones. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Breast Cancer
- What is being tested?
- Surveys and Video
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 6 Jan 2026to 31 Dec 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: MD Anderson Cancer Center
Who may be able to join
- Live, work, or worship in the Acres Homes community or live in surrounding neighborhoods with similar community characteristics
- Be 18 years of age and older
- Self-report a breast cancer diagnosis including subtypes OR be a family member of a survivor
- If a breast cancer survivor: current, former, or non-participant of the ALAC program
- Able to communicate in English
Who cannot join
- Self-report metastatic breast cancer diagnosis
- Unable to communicate in English
- Not a breast cancer survivor or family member of a survivor
Trial locations and contacts
1 site in 1 country.
United States1 site
The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030
About this study
Official title: Excessive Weight, Breast Cancer, and Endocrine Disrupting Chemicals (EDCs): Findings From Active Living After Cancer (ALAC) With Environmental Vitality
To learn about breast cancer survivors' and their family members' knowledge of and interest in learning about environmental exposures related to personal care products. Researchers also want to learn if there is a link between excessive weight and chemicals that may affect hormones.
Read the detailed description
Primary Objectives:
Excessive body weight, endocrine disrupting chemicals (EDCs), and breast cancer are interconnected through disruptions in hormone balance, with notable disparities in risk and outcomes for under-resourced communities. Under-resourced communities face compounding risks including aggressive late-stage diagnoses and healthcare access barriers that contribute to elevated breast cancer mortality. This proposal engages participants from the Acres Homes community and surrounding neighborhoods, including Active Living After Cancer (ALAC) participants, breast cancer survivors not enrolled in ALAC, and family members to assess knowledge and interest in environmental exposure education focused on personal care products, supporting development of the ALAC with Environmental Vitality (ALAC-ENV) intervention and examine associations between prevalent EDCs and excessive weight for breast cancer survivors and their family members.
Specific Aim 1: Determine survivors' and family members' environmental exposure knowledge. Participants (n=30) will participate in interviews to assess their interest and understanding of environmental exposures with an emphasis on personal care products.
Specific Aim 2: Determine the relationship between exposures to prevalent EDCs and BMI. A cross-sectional design to examine associations between BMI and measurements of non-persistent EDCs in urine and wristband samples of cancer survivors and family members.
Findings will inform an R-level grant to develop a randomized trial testing the efficacy of an adapted ALAC-ENV curriculum for dissemination and implementation in community settings, as well as foundation grant support fora cross-sectional study examining the association between body mass index, EDC exposure, and cancer in Acres Homes within the context of non-medical drivers of health.
- Conditions
- Breast Cancer
- Being tested
- Surveys, Video
- Medical subject headings
- Breast Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
SurveysOther
Electronic surveys will completed via REDCap.
VideoOther
Interviews and community forums will be conducted via videoconference (Zoom)
SurveysOther
Electronic surveys will completed via REDCap.
| Study group | Role | What they receive |
|---|---|---|
| Pre-Interview Survey | Before your interview, you will complete computer-based surveys about your age, biological sex, gender, income, highest level of education, marital status, insurance status, and health behaviors. The online surveys may take up to 40 minutes to complete. Receives: Other: Surveys | |
| Interview | After completing the pre-interview surveys, you will be scheduled for an interview. The interview will include a warm-up discussion, a short audiovisual presentation describing endocrine-disrupting chemicals (EDCs), and open-ended questions facilitating discussions on environmental exposures and personal care product usage from your perspective.
Interviews will occur by Zoom video conferencing and will be audio- and video-recorded. The recording will be transcribed (written down) word-for-word, but without your name or any other identifying information. The digital audio and video files will be destroyed after they are transcribed. Receives: Other: Video | |
| Post-Interview Survey | After your interview, you will complete a computer-based survey to help researchers understand the products you use and things that you do in your everyday life, provide urine samples, and wear a wristband. Receives: Other: Surveys |
What is being measured
The primary outcome is the main question the study is designed to answer.
Outcome Measure
Questionnaires/Videos
Measured: Through study completion; an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Aug 2025
- Study start6 Jan 2026
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Breast CancerStudies of the same condition, open and under way.
- More trials run by M.D. Anderson Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- M.D. Anderson Cancer Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Dede Teteh-Brooks, DRPH, Principal investigator, M.D. Anderson Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07137468
- Sponsor's protocol ID
- 2025-0698
- Other IDs
- NCI-2025-06013
- Status last verified
- Sep 2026
- First submitted
- 15 Aug 2025
- Last updated
- 15 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Excessive Weight, Breast Cancer, and Endocrine Disrupting Chemicals (EDCs): Findings From Active Living After Cancer (ALAC) With Environmental Vitality
- ClinicalTrials.gov ID
- NCT07137468
- Acronym / sponsor ID
- 2025-0698
- Conditions
- Breast Cancer
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- M.D. Anderson Cancer CenterUniversity, hospital or other
- Study start
- 6 Jan 2026 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 22 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To learn about breast cancer survivors' and their family members' knowledge of and interest in learning about environmental exposures related to personal care products. Researchers also want to learn if there is a link between excessive weight and chemicals that may affect hormones.
Detailed description
Primary Objectives:
Excessive body weight, endocrine disrupting chemicals (EDCs), and breast cancer are interconnected through disruptions in hormone balance, with notable disparities in risk and outcomes for under-resourced communities. Under-resourced communities face compounding risks including aggressive late-stage diagnoses and healthcare access barriers that contribute to elevated breast cancer mortality. This proposal engages participants from the Acres Homes community and surrounding neighborhoods, including Active Living After Cancer (ALAC) participants, breast cancer survivors not enrolled in ALAC, and family members to assess knowledge and interest in environmental exposure education focused on personal care products, supporting development of the ALAC with Environmental Vitality (ALAC-ENV) intervention and examine associations between prevalent EDCs and excessive weight for breast cancer survivors and their family members.
Specific Aim 1: Determine survivors' and family members' environmental exposure knowledge. Participants (n=30) will participate in interviews to assess their interest and understanding of environmental exposures with an emphasis on personal care products.
Specific Aim 2: Determine the relationship between exposures to prevalent EDCs and BMI. A cross-sectional design to examine associations between BMI and measurements of non-persistent EDCs in urine and wristband samples of cancer survivors and family members.
Findings will inform an R-level grant to develop a randomized trial testing the efficacy of an adapted ALAC-ENV curriculum for dissemination and implementation in community settings, as well as foundation grant support fora cross-sectional study examining the association between body mass index, EDC exposure, and cancer in Acres Homes within the context of non-medical drivers of health.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Pre-Interview Survey | – | Other: SurveysBefore your interview, you will complete computer-based surveys about your age, biological sex, gender, income, highest level of education, marital status, insurance status, and health behaviors. The online surveys may take up to 40 minutes to complete. |
| Interview | – | Other: VideoAfter completing the pre-interview surveys, you will be scheduled for an interview. The interview will include a warm-up discussion, a short audiovisual presentation describing endocrine-disrupting chemicals (EDCs), and open-ended questions facilitating discussions on environmental exposures and personal care product usage from your perspective. Interviews will occur by Zoom video conferencing and will be audio- and video-recorded. The recording will be transcribed (written down) word-for-word, but without your name or any other identifying information. The digital audio and video files will be destroyed after they are transcribed. |
| Post-Interview Survey | – | Other: SurveysAfter your interview, you will complete a computer-based survey to help researchers understand the products you use and things that you do in your everyday life, provide urine samples, and wear a wristband. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- MD Anderson Cancer Center
Key inclusion criteria (5 listed)
- Live, work, or worship in the Acres Homes community or live in surrounding neighborhoods with similar community characteristics
- Be 18 years of age and older
- Self-report a breast cancer diagnosis including subtypes OR be a family member of a survivor
- If a breast cancer survivor: current, former, or non-participant of the ALAC program
- Able to communicate in English
Key exclusion criteria (3 listed)
- Self-report metastatic breast cancer diagnosis
- Unable to communicate in English
- Not a breast cancer survivor or family member of a survivor
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| SurveysElectronic surveys will completed via REDCap. | Other | Pre-Interview Survey |
| VideoInterviews and community forums will be conducted via videoconference (Zoom) | Other | Interview |
| SurveysElectronic surveys will completed via REDCap. | Other | Post-Interview Survey |
Primary outcome
Outcome Measure
Time frame: Through study completion; an average of 1 year
Questionnaires/Videos
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Sep 2026.
- MD Anderson Cancer Center WebsiteLink provided by the sponsor.
Related trials for Breast Cancer
Active, not recruiting
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
Breast Cancer, Comorbidities and Coexisting Conditions
RecruitingPhase 2
Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
Invasive Mammary Carcinoma, Metastatic Breast Cancer
Not yet recruitingObservational study
Comparison of Reliability, Time Cost, and Participant Comfort of Lymphedema Assessments in Upper Extremity
Lymphedema, Upper Extremity Lymphedema
RecruitingPhase 3
A Study of Camrelizumab Plus Chemotherapy in Combination With or Without Famitinib as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (BCTOP-T-N01)
TNBC - Triple-Negative Breast Cancer
RecruitingPhase 3
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dede Teteh-Brooks, DRPH principal investigator
M.D. Anderson Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Breast Cancer, run by M.D. Anderson Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 15 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Outcome Measure (time frame: Through study completion; an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Sep 2026.