Chronic Non-specific Neck PainNCT07132229
Impact Of Cervical High-Intensity Resistive Exercises In Patients With Chronic Non-Specific Neck Pain
A study testing Cervical High-Intensity Resistive Exercises and Conventional physical therapy in people with Chronic Non-specific Neck Pain, run by Cairo University at 1 site in Egypt.
Trial summary
Purposes of the study To investigate the effect of adding Cervical High-Intensity Resistive Exercises to conventional physical therapy in patients with Chronic Non-Specific Neck Pain Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Chronic Non-specific Neck Pain
- What is being tested?
- Cervical High-Intensity Resistive Exercises and Conventional physical therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Aug 2025to 1 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Thirty-four patients diagnosed CNSNP.
- Age of the patients between 20-40 years.
- Non-specific neck pain started more than 3 months.
- Reduce ventilatory function; FVC >= 70% from predicted.
- Waist to height ratio (WtHR)> 60 %.
- Positive craniocervical flexion test.
Show all 9Show fewer
- Positive neck flexor endurance test.
- Pain at neck after prolonged static weight bearing positions.
- Pain with palpation of the neck paraspinal or suboccipital or trapezius muscles.
Who cannot join
- History of whiplash injury.
- Clinical sign of cervical radiculopathy.
- Clinical signs of cervical myelopathy.
- Rheumatoid Arthritis or any other autoimmune diseases.
- Any respiratory disorders.
- Tumors.
- vertebrobasilar insufficiency VBI.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
outpatient clinic, Faculty of Physical Therapy, Cairo University
Giza, Egypt, 12613
Taha Elbragily, MSc, +20 103 382 3380, Tahaahmed.ta218@gmail.com
About this study
Official title: Impact of Cervical High-Intensity Resistive Exercises on Ventilatory Measures in Patients With Chronic Non-Specific Neck Pain
Purposes of the study
To investigate the effect of adding Cervical High-Intensity Resistive Exercises to conventional physical therapy in patients with Chronic Non-Specific Neck Pain
Read the detailed description
Patients will be randomized into either Cervical High-Intensity Resistive Exercises group or Conventional physical therapy group. Patients will receive the intervention for six weeks. Outcomes will be assessed at baseline and post-intervention.
- Conditions
- Chronic Non-specific Neck Pain
- Being tested
- Cervical High-Intensity Resistive Exercises, Conventional physical therapy
- Keywords
- neck pain, cervical pain, High-Intensity Resistive Exercises
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cervical High-Intensity Resistive ExercisesOther
The patient will wear a neck harness, and a weight equivalent to 90% of the patient's measured maximum voluntary isometric contraction (MVIC) will be attached to it.
Conventional physical therapyOther
Conventional physical therapy consisting of TENS for pain control, soft tissue release for the cervical and associated muscles, activation and strengthening exercises for the deep neck flexors, extensors, and scapular muscles, as well as diaphragmatic breathing exercises.
| Study group | Role | What they receive |
|---|---|---|
| Cervical High-Intensity Resistive Exercises + Conventional physical therapy | Experimental | Patients in this group will receive Cervical High-Intensity Resistive Exercises + Conventional physical therapy Receives: Other: Cervical High-Intensity Resistive Exercises; Other: Conventional physical therapy |
| Conventional physical therapy | Active comparator | Patients in this group will receive Conventional physical therapy Receives: Other: Conventional physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Disability
Neck disability index (NDI)
Measured: Change from Baseline Disability at 6 weeks
Diaphragm thickness
Ultrasound
Measured: Change from Baseline Diaphragm thickness at 6 weeks
Forced vital capacity (FVC)
Spirometry
Measured: Change from Baseline Forced vital capacity (FVC) at 6 weeks
maximum voluntary ventilation (MVV)
Spirometry
Measured: Change from maximum voluntary ventilation (MVV) at 6 weeks
Secondary outcomes (2)
Neck pain
Visual analogue scale
Measured: Change from Baseline Neck pain at 6 weeks
Strength of neck flexors, extensors, and side bending
Hand-held dynamometer (HHD)
Measured: Change from Baseline Strength of neck flexors, extensors, and side bending at 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Aug 2025
- Study start10 Aug 2025 (estimated)
- Primary completion1 Feb 2026 (estimated)
- Study completion1 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Non-specific Neck PainStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 34 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Taha Ahmed Taha Elbragily, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07132229
- Sponsor's protocol ID
- P.T.REC/012/004930
- Status last verified
- Aug 2025
- First submitted
- 5 Aug 2025
- Last updated
- 20 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 20 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Cervical High-Intensity Resistive Exercises on Ventilatory Measures in Patients With Chronic Non-Specific Neck Pain
- ClinicalTrials.gov ID
- NCT07132229
- Acronym / sponsor ID
- P.T.REC/012/004930
- Conditions
- Chronic Non-specific Neck Pain
- Keywords
- neck pain, cervical pain, High-Intensity Resistive Exercises
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 34 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Aug 2025 (estimated)
- Primary completion
- 1 Feb 2026 (estimated)
- Study completion
- 1 Feb 2026 (estimated)
- First posted
- 20 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Purposes of the study
To investigate the effect of adding Cervical High-Intensity Resistive Exercises to conventional physical therapy in patients with Chronic Non-Specific Neck Pain
Detailed description
Patients will be randomized into either Cervical High-Intensity Resistive Exercises group or Conventional physical therapy group. Patients will receive the intervention for six weeks. Outcomes will be assessed at baseline and post-intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Cervical High-Intensity Resistive Exercises + Conventional physical therapy | Experimental | Other: Cervical High-Intensity Resistive Exercises, Other: Conventional physical therapyPatients in this group will receive Cervical High-Intensity Resistive Exercises + Conventional physical therapy |
| Conventional physical therapy | Active comparator | Other: Conventional physical therapyPatients in this group will receive Conventional physical therapy |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (9 listed)
- Thirty-four patients diagnosed CNSNP.
- Age of the patients between 20-40 years.
- Non-specific neck pain started more than 3 months.
- Reduce ventilatory function; FVC >= 70% from predicted.
- Waist to height ratio (WtHR)> 60 %.
Key exclusion criteria (7 listed)
- History of whiplash injury.
- Clinical sign of cervical radiculopathy.
- Clinical signs of cervical myelopathy.
- Rheumatoid Arthritis or any other autoimmune diseases.
- Any respiratory disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cervical High-Intensity Resistive ExercisesThe patient will wear a neck harness, and a weight equivalent to 90% of the patient's measured maximum voluntary isometric contraction (MVIC) will be attached to it. | Other | Cervical High-Intensity Resistive Exercises + Conventional physical therapy |
| Conventional physical therapyConventional physical therapy consisting of TENS for pain control, soft tissue release for the cervical and associated muscles, activation and strengthening exercises for the deep neck flexors, extensors, and scapular muscles, as well as diaphragmatic breathing exercises. | Other | Cervical High-Intensity Resistive Exercises + Conventional physical therapy, Conventional physical therapy |
Primary outcome
Disability
Time frame: Change from Baseline Disability at 6 weeks
Neck disability index (NDI)
Diaphragm thickness
Time frame: Change from Baseline Diaphragm thickness at 6 weeks
Ultrasound
Forced vital capacity (FVC)
Time frame: Change from Baseline Forced vital capacity (FVC) at 6 weeks
Spirometry
maximum voluntary ventilation (MVV)
Time frame: Change from maximum voluntary ventilation (MVV) at 6 weeks
Spirometry
2 secondary outcomes
Neck pain
Time frame: Change from Baseline Neck pain at 6 weeks
Strength of neck flexors, extensors, and side bending
Time frame: Change from Baseline Strength of neck flexors, extensors, and side bending at 6 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Aug 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
outpatient clinic, Faculty of Physical Therapy, Cairo University
Giza, Egypt
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cervical High-Intensity Resistive Exercises and Conventional physical therapy in people with Chronic Non-specific Neck Pain, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Disability (time frame: Change from Baseline Disability at 6 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Aug 2025.