Patients With Trigger FingerNCT07128043
The Effect of Cassava Waxes Hot Bath on Pain, Pressure Pain Threshold and Hand Function Among Patients With Trigger Finger
A study testing ultrasound therapy and cassava wax hot immersion and ultrasound therapy in people with Patients With Trigger Finger, run by University of Phayao at 1 site in Thailand.
Trial summary
Objective: This study aimed to evaluate the efficacy of cassava wax hand immersion combined with ultrasound therapy on pain severity, pain threshold, finger locking frequency, and hand functional ability in patients with trigger finger. We assessed immediate, short-term, and long-term treatment outcomes. Read more about this study
- Who is it for?
- Ages 40 to 70 years
- Conditions the study is for
- Patients With Trigger Finger
- What is being tested?
- ultrasound therapy and cassava wax hot immersion and ultrasound therapy
- Type of treatment
- Medical device
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 40 participants
- Where
- 1 siteThailand
- Study dates
- 1 Sep 2025to 30 Oct 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Having a diagnosis of trigger finger by a physician or a specialized physical therapist
- Present with all of the following symptoms: pain at the base of the affected finger, triggering (catching/locking) as a primary symptom (though pain often increased with it), and a palpable or audible triggering sensation during finger flexion and extension.
- Able to understand and follow the research procedures.
Who cannot join
- Having a history of neurological conditions, such as stroke or diseases causing sensory impairment in the upper limbs.
- Having arthritis or infection in the upper limbs
- Having Rheumatoid Arthritis.
- Having a skin condition in the wrist or hand area, upper limb fractures within the last 6 months, or those affecting movement.
- Having musculoskeletal deformities of the upper limbs that impact movement.
- Having an inflammation (e.g., pain, swelling, redness, warmth) in the wrist and fingers
- Having a history of upper limb surgery, an allergy to cassava starch/flour.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effect of Cassava Waxes Hot Bath on Pain, Pressure Pain Threshold and Hand Function Among Patient With Trigger Finger: Single-Blind Randomized Controlled Trial Study
Objective: This study aimed to evaluate the efficacy of cassava wax hand immersion combined with ultrasound therapy on pain severity, pain threshold, finger locking frequency, and hand functional ability in patients with trigger finger. We assessed immediate, short-term, and long-term treatment outcomes.
Methods: This was a randomized controlled trial. Thirty-eight eligible volunteers were randomly assigned to two groups. The experimental group received ultrasound therapy combined with cassava wax hand immersion, while the control group received ultrasound therapy alone. Treatments were administered three times per week for four weeks.
- Conditions
- Patients With Trigger Finger
- Being tested
- ultrasound therapy and cassava wax hot immersion, ultrasound therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ultrasound therapy and cassava wax hot immersionDevice
participants sat in a comfortable position with their hand placed on a pillow or cushion. Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm. Afterward, the hand was cleaned and immersed in cassava wax heated to 125°F (51.7°C). The affected hand was dipped into the wax for 3 seconds, then removed. This process was repeated for 10 cycles. The hand was then wrapped in a plastic bag and a towel for 15 minutes before the wax was removed and peeled off.
ultrasound therapyDevice
- ultrasound therapy Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm.
| Study group | Role | What they receive |
|---|---|---|
| ultrasound therapy combined with cassava wax hot immersion | Experimental | ultrasound therapy combined with cassava wax hot immersion group and ultrasound therapy only Receives: Device: ultrasound therapy and cassava wax hot immersion |
| ultrasound therapy | Sham comparator | ultrasound therapy Receives: Device: ultrasound therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analog Scale (VAS)
This assesses the current pain severity using a 10-centimeter scale. Scores range from 0 to 10, where the far left end of the scale indicates "no pain at all" (score of 0), and the far right end indicates "worst pain imaginable" (score of 10). Participants were asked to mark an 'X' on the scale at the point corresponding to their current pain severity.
Measured: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.
Pressure pain threshold
Participants were seated, and the assessor identified the location of the myofascial trigger point. This spot was marked with a washable pen. An algometer (a device used to measure pain threshold) was then applied to the marked trigger point at a rate of approximately 1 kg/second. Participants were instructed to signal immediately upon feeling the onset of pain (pain threshold). The applied pressure ranged from 0 to 11 kg/cm. Each participant underwent three measurements, with a 3-minute rest interval between each. The average of these three measurements was then calculated.
Measured: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.
Pain frequency
Participants were interviewed regarding the frequency of finger locking symptoms and the number of finger locking episodes per day.
Measured: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.
Disability of the arm, shoulder and hand
This is a questionnaire designed to assess the level of upper extremity impairment. It evaluates the functional ability of the wrist and finger joints, comprising 30 questions related to the patient's daily life activities and work capacity.
Measured: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2025
- Study start1 Sep 2025 (estimated)
- Primary completion30 Sep 2025 (estimated)
- Study completion30 Oct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patients With Trigger FingerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Arm 1: Name: Cassava waxes hot bath group ( Experimental group) Type: Experimental Description: Ultrasound therapy combined with cassava wax hot immersion Arm 2: Name: Control or comparison group Type: Active Comparator (Control) Description: Ultrasound therapy only
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Phayao
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Chonticha Kaewjoho, University of Phayao
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07128043
- Sponsor's protocol ID
- NarongsakMFU2568
- Status last verified
- Aug 2025
- First submitted
- 31 Jul 2025
- Last updated
- 17 Aug 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Cassava Waxes Hot Bath on Pain, Pressure Pain Threshold and Hand Function Among Patient With Trigger Finger: Single-Blind Randomized Controlled Trial Study
- ClinicalTrials.gov ID
- NCT07128043
- Acronym / sponsor ID
- NarongsakMFU2568
- Conditions
- Patients With Trigger Finger
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- University of PhayaoUniversity, hospital or other
- Study start
- 1 Sep 2025 (estimated)
- Primary completion
- 30 Sep 2025 (estimated)
- Study completion
- 30 Oct 2025 (estimated)
- First posted
- 17 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objective: This study aimed to evaluate the efficacy of cassava wax hand immersion combined with ultrasound therapy on pain severity, pain threshold, finger locking frequency, and hand functional ability in patients with trigger finger. We assessed immediate, short-term, and long-term treatment outcomes.
Methods: This was a randomized controlled trial. Thirty-eight eligible volunteers were randomly assigned to two groups. The experimental group received ultrasound therapy combined with cassava wax hand immersion, while the control group received ultrasound therapy alone. Treatments were administered three times per week for four weeks.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Arm 1: Name: Cassava waxes hot bath group ( Experimental group) Type: Experimental Description: Ultrasound therapy combined with cassava wax hot immersion Arm 2: Name: Control or comparison group Type: Active Comparator (Control) Description: Ultrasound therapy only
| Arm | Type | Receives |
|---|---|---|
| ultrasound therapy combined with cassava wax hot immersion | Experimental | Device: ultrasound therapy and cassava wax hot immersionultrasound therapy combined with cassava wax hot immersion group and ultrasound therapy only |
| ultrasound therapy | Sham comparator | Device: ultrasound therapyultrasound therapy |
Who may qualify
- Ages
- 40 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Having a diagnosis of trigger finger by a physician or a specialized physical therapist
- Present with all of the following symptoms: pain at the base of the affected finger, triggering (catching/locking) as a primary symptom (though pain often increased with it), and a palpable or audible triggering sensation during finger flexion and extension.
- Able to understand and follow the research procedures.
Key exclusion criteria (7 listed)
- Having a history of neurological conditions, such as stroke or diseases causing sensory impairment in the upper limbs.
- Having arthritis or infection in the upper limbs
- Having Rheumatoid Arthritis.
- Having a skin condition in the wrist or hand area, upper limb fractures within the last 6 months, or those affecting movement.
- Having musculoskeletal deformities of the upper limbs that impact movement.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ultrasound therapy and cassava wax hot immersionparticipants sat in a comfortable position with their hand placed on a pillow or cushion. Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm. Afterward, the hand was cleaned and immersed in cassava wax heated to 125°F (51.7°C). The affected hand was dipped into the wax for 3 seconds, then removed. This process was repeated for 10 cycles. The hand was then wrapped in a plastic bag and a towel for 15 minutes before the wax was removed and peeled off. | Device | ultrasound therapy combined with cassava wax hot immersion |
| ultrasound therapy1. ultrasound therapy Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm. | Device | ultrasound therapy |
Primary outcome
Visual Analog Scale (VAS)
Time frame: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.
This assesses the current pain severity using a 10-centimeter scale. Scores range from 0 to 10, where the far left end of the scale indicates "no pain at all" (score of 0), and the far right end indicates "worst pain imaginable" (score of 10). Participants were asked to mark an 'X' on the scale at the point corresponding to their current pain severity.
Pressure pain threshold
Time frame: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.
Participants were seated, and the assessor identified the location of the myofascial trigger point. This spot was marked with a washable pen. An algometer (a device used to measure pain threshold) was then applied to the marked trigger point at a rate of approximately 1 kg/second. Participants were instructed to signal immediately upon feeling the onset of pain (pain threshold). The applied pressure ranged from 0 to 11 kg/cm. Each participant underwent three measurements, with a 3-minute rest interval between each. The average of these three measurements was then calculated.
Pain frequency
Time frame: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.
Participants were interviewed regarding the frequency of finger locking symptoms and the number of finger locking episodes per day.
Disability of the arm, shoulder and hand
Time frame: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.
This is a questionnaire designed to assess the level of upper extremity impairment. It evaluates the functional ability of the wrist and finger joints, comprising 30 questions related to the patient's daily life activities and work capacity.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ultrasound therapy and cassava wax hot immersion and ultrasound therapy in people with Patients With Trigger Finger, run by University of Phayao at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 17 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analog Scale (VAS) (time frame: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2025.