Grade 1 Anterior Cruciate Ligament InjuryNCT07115316
EFFECTIVENESS OF ECCENTRIC HAMSTRING CONTRACTIONS WITH PHYSIOTHERAPY TRAINING ON SPORTS PERFORMANCE AND QUALITY OF LIFE IN YOUNG MALE FOOTBALL PLAYERS WITH NON-CONTACT GRADE 1 ACL INJURY
A study testing Exercises in people with Grade 1 Anterior Cruciate Ligament Injury, run by Emirates Health Services (EHS) at 1 site in United Arab Emirates.
Trial summary
The overall aim of the study is to evaluate the impact of eccentric hamstring contractions on sports performance in young male football players with non-contact grade 1 Anterior Cruciate Ligament injuries. Read more about this study
- Who is it for?
- Ages 19 to 25 years, men only
- Conditions the study is for
- Grade 1 Anterior Cruciate Ligament Injury
- What is being tested?
- Exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 180 participants
- Where
- 1 siteUnited Arab Emirates
- Study dates
- 9 Aug 2025to 30 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 to 25 years
- Men only
- No healthy volunteers
- Adult
Who may be able to join
- physician-diagnosed non-contact acute grade 1 ACL injury within the past 6 weeks will be invited from the selected clubs for participation in the trial. Participants who can perform full Range of Motion in the injured knee without pain will be included. Male football players between age 19-25 years old, currently playing in UAE, who speak English language and with physician-diagnosed non-contact grade 1 ACL injury will be included in the trial.
Who cannot join
- • Players with contact ACL injuries.
- Players with chronic grade 1 ACL Injuries.
- If pain and swelling are severe and occur within 24 hours after exercise, will be excluded from the study.
- Grade 2 and above ACL injuries.
- Female players.
- Players aged below 18 years or above 25 years.
Show all 11Show fewer
- Players with a history of surgery on the same knee.
- Players with injuries to the menisci or other ligaments.
- Players who do not speak English.
- Players who refuse to provide written informed consent to participate in the trial.
- Players currently enrolled in other formal rehabilitation programs.
Trial locations and contacts
1 site in 1 country.
United Arab Emirates1 site
Emirates Health services
Ras al-Khaimah, Emirate of Ras Al Khaimah, 0000
About this study
Official title: A RANDOMIZED, OPEN-LABEL TRIAL TO EVALUATE THE CLINICAL EFFECTIVENESS OF ECCENTRIC HAMSTRING CONTRACTIONS WITH PHYSIOTHERAPY TRAINING ON SPORTS PERFORMANCE AND QUALITY OF LIFE IN YOUNG MALE FOOTBALL PLAYERS WITH NON-CONTACT GRADE 1 ACL INJURY
The overall aim of the study is to evaluate the impact of eccentric hamstring contractions on sports performance in young male football players with non-contact grade 1 Anterior Cruciate Ligament injuries.
Treatment allocation will be assigned using an automated randomization process developed by an independent person who is not involved in the study. Computer-generated random numbers will be used for randomization into two groups.
Read more
Inclusion criteria Eligible patients with physician-diagnosed non-contact acute grade 1 ACL injury within the past 6 weeks will be invited from the selected clubs for participation in the trial. Participants who can perform full Range of Motion in the injured knee without pain will be included. Male football players between age 19-25 years old, currently playing in UAE, who speak English language and with physician-diagnosed non-contact grade 1 ACL injury will be included in the trial.
Exclusion Criteria
- Players with contact ACL injuries.
- Players with chronic grade 1 ACL Injuries.
- If pain and swelling are severe and occur within 24 hours after exercise, will be excluded from the study.
- Grade 2 and above ACL injuries.
- Female players.
- Players aged below 18 years or above 25 years.
- Players with a history of surgery on the same knee.
- Players with injuries to the menisci or other ligaments.
- Players who do not speak English.
- Players who refuse to provide written informed consent to participate in the trial.
- Players currently enrolled in other formal rehabilitation programs. There is no invasive procedure to be done. It focuses on strengthening the hamstrings muscle, specifically through eccentric contractions, which involve lengthening the muscle while it's under tension along with normal physiotherapy exercises.
The comparator group receives a variety of physiotherapy exercises aimed at improving strength, flexibility, and balance around the knee. For those patients who have mild pain or swelling will also be given TENS and Ultrasound.
Read the detailed description
ACL injuries are prevalent in sports, particularly in activities that involve sudden stops, changes in direction, or direct impact on the knee. These injuries can have significant consequences, including pain, instability, and long-term joint damage(Montalvo et al., 2019). Understanding the mechanisms and risk factors for ACL injury is crucial for injury prevention and rehabilitation(Takahashi \& Okuwaki, 2017). Eccentric contraction involves the elongation of a muscle while it is under tension. The hamstrings are a muscle group situated at the back of the thigh, comprising the biceps femoris, semitendinosus, and semimembranosus. The hamstrings play a crucial role in knee stability, particularly in preventing excessive anterior translation of the tibia relative to the femur, which is one of the mechanisms of ACL injury (Gronwald et al., 2022). Strengthening the hamstrings, especially through eccentric contractions, can enhance knee joint stability(Jones et al., 2019). Eccentric muscle contractions involve the lengthening of a muscle while it is contracting. These contractions are particularly effective in building strength and improving muscle function (Al Attar et al., 2017). Research suggests that eccentric hamstring strengthening exercises can enhance muscle activation, increase muscle strength, and improve neuromuscular control, all beneficial in ACL rehabilitation (Opar et al., 2012). Eccentric strengthening exercises for the hamstrings are commonly prescribed in rehabilitation programs for ACL injuries, because they provide dynamic stability to the knee joint (Lodge et al., 2019). ACL injury often occurs during dynamic movements such as cutting, pivoting, or landing from a jump. Biomechanical studies have identified specific movement patterns and muscle activation sequences associated with ACL injury risk (Buckthorpe et al., 2019).
Rehabilitation protocols for ACL reconstruction typically include strengthening exercises, neuromuscular training, proprioceptive exercises, and functional activities. Eccentric hamstring exercises are commonly incorporated into these programs to improve muscle strength, control, and proprioception around the knee joint(Vatovec et al., 2020).
Despite the widespread use of eccentric hamstring training in ACL rehabilitation after reconstruction, there may be gaps in our understanding of the effectiveness of eccentric hamstring contractions in ACL rehabilitation,for rehabilitation after ACLR, progressive eccentric cycle training was not more clinically effective than concentric training (Giovanni Milandri, Sudesh Sivarasu, 2021). Addressing these gaps can provide valuable insights for providing rehabilitation protocols and enhancing outcomes for individuals recovering from ACL injury.
Overall, the background of the study highlights the importance of understanding the relationship between eccentric hamstring contraction and ACL grade 1 injury rehabilitation. The study aims to provide insights into how eccentric hamstring contraction may influence ACL grade 1 injury rehabilitation.
- THE OBJECTIVE OF THE STUDY
- To assess the effectiveness of eccentric hamstring contractions on changes in sports performance, using various testing methods, in the intervention group.
- To evaluate the impact of eccentric hamstring contractions on quality of life and psychological well-being in young male football players with non-contact grade 1 ACL injury.
- To compare sports performance outcomes between the intervention and control groups in young male football players with non-contact grade 1 ACL injury.
The overall aim of the study is to evaluate the impact of eccentric hamstring contractions on sports performance in young male football players with non-contact grade 1 ACL injuries hamstring exercises on sports performance among young male football players with non-contact grade 1 ACL injury in UAE. The participants recruited in the study will be randomly assigned to one of two intervention groups: a control arm (usual physiotherapy exercise will be given) and, an intervention Arm (custom-tailored eccentric hamstring exercises along with physiotherapy will be given). We assumed no interaction between the treatment arms.
Operational Definitions
- ACL - The anterior cruciate ligament (ACL) is one of 2 cruciate ligaments that aids in stabilizing the knee joint. It is a strong band made of connective tissue and collagenous fibers that originate from the anteromedial aspect of the intercondylar region of the tibial plateau and extends posterolaterally to attach to the medial aspect of the lateral femoral condyle, where there are two important landmarks; The lateral intercondylar ridge which defines the anterior boundary of the ACL, and the bifurcate ridge which separates the 2 ACL bundles(Evans J, 2023).
- Eccentric hamstring exercises - An eccentric strengthening exercise program for the hamstring muscles that can be performed during training can help prevent hamstring injuries in soccer players(Schache A, 2012).
- Nordic hamstring curl training (NHCT), a type of training based on eccentric contractions aimed at increasing hamstring muscle strength and performed on flat ground without requiring special equipment, has been accepted as a popular training method(Al Attar, 2017).
- Running, one of the most basic human motions, is characterized by a typical cyclic motion and an airborne phase involving projection of the body. Sprint running is recognized as the fastest mode of unaided human locomotion (Michiyoshi Ae, 2017).
Pain Categories:
- Mild: Pain intensity 1-3/10, occasional discomfort, no interference with daily tasks.
- Moderate: Pain intensity 4-6/10, noticeable during activities, some difficulty with strenuous movements.
- Severe: Pain intensity 7-10/10, significant pain at rest and with movement, difficulty with daily activities.
- Swelling Categories:
- Mild: Slight increase in size, no significant loss of motion, resolves with rest.
- Moderate: Noticeable swelling, some difficulty with knee movement, lasts several hours or days.
- Severe: Significant swelling, major restriction of movement, may require medical intervention.
- Being tested
- Exercises
- Keywords
- Eccentric hamstring exercises
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ExercisesOther
- Nordic hamstring curls
- Seated leg curls
- Prone leg curls
- Knee Straightening (Extension)
- Knee Bend (Flexion)
- Inner Range Quads
- Straight Leg Raise
- Lunge to Split Lunge
- Single Leg Sit to Stand
- Standing Hamstring Curls
- Double/Single Leg Bridge
- Side Lie Hip Abductions
- Crab Walks
- Forward Step Ups
- Calf Raises
- Single Leg Balance
- Clock Face Mini Squat
- Arabesque Clock
- Two-Legged Jump / Single-Legged Hop
| Study group | Role | What they receive |
|---|---|---|
| Control Arm (conventional physiotherapy) | Active comparator | Receives conventional physiotherapy alone
1. Knee Straightening (Extension)
2. Knee Bend (Flexion):
3. Inner Range Quads
4. Straight Leg Raise
5. Lunge to Split Lunge
6. Single Leg Sit to Stand
7. Standing Hamstring Curls
8. Double/Single Leg Bridge
9. Side Lie Hip Abductions
10. Crab Walks
11. Forward Step Ups
12. Calf Raises.
13. Single Leg Balance
14. Clock Face Mini Squat
15. Arabesque Clock
16. Two-Legged Jump / Single-Legged Hop Receives: Other: Exercises |
| Experimental Arm | Experimental | Receives both intervention exercises and conventional physiotherapy Receives: Other: Exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
ACL Quality of Life (ACL-QOL) questionnaire
Description: The ACL-QOL is a self-administered scale composed of 32 items divided into 5 domains: symptoms and physical complaints (5 items), work-related concerns (4 items), recreational activity and sport participation or competition Each domain has a proportional value according to the number of questions and is assessed with a 100-mm visual analog scale. A higher score indicates a better QOL
Measured: first intervention day and 3 months
Secondary outcomes (1)
Sargent vertical jump test
.The athlete warms up for 10 minutes. The athlete chalks the end of their fingertips. The athlete stands side onto the wall, keeping both feet remaining on the ground, reaches up as high as possible with one hand and marks the wall with the tips of the fingers (M1). From a static position, the athlete jumps as high as possible and marks the wall with the chalk on his fingers (M2).The therapist measures and records the distance between M1 and M2. The athlete repeats the test 3 times. The therapist calculates the average of the recorded distances and uses this value to assess the athlete's performance.
Measured: First day of intervention and at 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Aug 2025
- Study start9 Aug 2025
- Primary completion30 Jan 2026
- Study completion30 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Grade 1 Anterior Cruciate Ligament InjuryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 180 participants (actual)
Sponsor and investigators
- Lead sponsor
- Emirates Health Services (EHS)
- Sponsor type
- Other government
- Collaborators
- Lincoln University College Malaysia
- Responsible party
- Principal investigator, Ajmal Sheriff, Emirates Health Services (EHS)
- Investigators
- Anil John, PhD, Principal investigator, Lincoln University College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07115316
- Sponsor's protocol ID
- MOHAP/DXB-REC/ J.F.M /No. 21/
- Status last verified
- Sep 2026
- First submitted
- 4 Aug 2025
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: As per the informed consent
Publications
Oliver GD, Dougherty CP. The razor curl: a functional approach to hamstring training. J Strength Cond Res. 2009 Mar;23(2):401-5. doi: 10.1519/JSC.0b013e31818f08d0.
PubMed 19204567Milandri G, Sivarasu S. A Randomized Controlled Trial of Eccentric Versus Concentric Cycling for Anterior Cruciate Ligament Reconstruction Rehabilitation. Am J Sports Med. 2021 Mar;49(3):626-636. doi: 10.1177/0363546520987566. Epub 2021 Feb 8.
PubMed 33555943Takahashi S, Okuwaki T. Epidemiological survey of anterior cruciate ligament injury in Japanese junior high school and high school athletes: cross-sectional study. Res Sports Med. 2017 Jul-Sep;25(3):266-276. doi: 10.1080/15438627.2017.1314290. Epub 2017 Apr 10.
PubMed 28391716
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A RANDOMIZED, OPEN-LABEL TRIAL TO EVALUATE THE CLINICAL EFFECTIVENESS OF ECCENTRIC HAMSTRING CONTRACTIONS WITH PHYSIOTHERAPY TRAINING ON SPORTS PERFORMANCE AND QUALITY OF LIFE IN YOUNG MALE FOOTBALL PLAYERS WITH NON-CONTACT GRADE 1 ACL INJURY
- ClinicalTrials.gov ID
- NCT07115316
- Acronym / sponsor ID
- MOHAP/DXB-REC/ J.F.M /No. 21/
- Keywords
- Eccentric hamstring exercises
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 180 participants (actual)
- Lead sponsor
- Emirates Health Services (EHS)Other government
- Collaborators
- Lincoln University College Malaysia
- Study start
- 9 Aug 2025 (actual)
- Primary completion
- 30 Jan 2026 (actual)
- Study completion
- 30 May 2026 (actual)
- First posted
- 11 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The overall aim of the study is to evaluate the impact of eccentric hamstring contractions on sports performance in young male football players with non-contact grade 1 Anterior Cruciate Ligament injuries.
Treatment allocation will be assigned using an automated randomization process developed by an independent person who is not involved in the study. Computer-generated random numbers will be used for randomization into two groups.
Inclusion criteria Eligible patients with physician-diagnosed non-contact acute grade 1 ACL injury within the past 6 weeks will be invited from the selected clubs for participation in the trial. Participants who can perform full Range of Motion in the injured knee without pain will be included. Male football players between age 19-25 years old, currently playing in UAE, who speak English language and with physician-diagnosed non-contact grade 1 ACL injury will be included in the trial.
Exclusion Criteria
- Players with contact ACL injuries.
- Players with chronic grade 1 ACL Injuries.
- If pain and swelling are severe and occur within 24 hours after exercise, will be excluded from the study.
- Grade 2 and above ACL injuries.
- Female players.
- Players aged below 18 years or above 25 years.
- Players with a history of surgery on the same knee.
- Players with injuries to the menisci or other ligaments.
- Players who do not speak English.
- Players who refuse to provide written informed consent to participate in the trial.
- Players currently enrolled in other formal rehabilitation programs. There is no invasive procedure to be done. It focuses on strengthening the hamstrings muscle, specifically through eccentric contractions, which involve lengthening the muscle while it's under tension along with normal physiotherapy exercises.
The comparator group receives a variety of physiotherapy exercises aimed at improving strength, flexibility, and balance around the knee. For those patients who have mild pain or swelling will also be given TENS and Ultrasound.
Detailed description
ACL injuries are prevalent in sports, particularly in activities that involve sudden stops, changes in direction, or direct impact on the knee. These injuries can have significant consequences, including pain, instability, and long-term joint damage(Montalvo et al., 2019). Understanding the mechanisms and risk factors for ACL injury is crucial for injury prevention and rehabilitation(Takahashi \& Okuwaki, 2017). Eccentric contraction involves the elongation of a muscle while it is under tension. The hamstrings are a muscle group situated at the back of the thigh, comprising the biceps femoris, semitendinosus, and semimembranosus. The hamstrings play a crucial role in knee stability, particularly in preventing excessive anterior translation of the tibia relative to the femur, which is one of the mechanisms of ACL injury (Gronwald et al., 2022). Strengthening the hamstrings, especially through eccentric contractions, can enhance knee joint stability(Jones et al., 2019). Eccentric muscle contractions involve the lengthening of a muscle while it is contracting. These contractions are particularly effective in building strength and improving muscle function (Al Attar et al., 2017). Research suggests that eccentric hamstring strengthening exercises can enhance muscle activation, increase muscle strength, and improve neuromuscular control, all beneficial in ACL rehabilitation (Opar et al., 2012). Eccentric strengthening exercises for the hamstrings are commonly prescribed in rehabilitation programs for ACL injuries, because they provide dynamic stability to the knee joint (Lodge et al., 2019). ACL injury often occurs during dynamic movements such as cutting, pivoting, or landing from a jump. Biomechanical studies have identified specific movement patterns and muscle activation sequences associated with ACL injury risk (Buckthorpe et al., 2019).
Rehabilitation protocols for ACL reconstruction typically include strengthening exercises, neuromuscular training, proprioceptive exercises, and functional activities. Eccentric hamstring exercises are commonly incorporated into these programs to improve muscle strength, control, and proprioception around the knee joint(Vatovec et al., 2020).
Despite the widespread use of eccentric hamstring training in ACL rehabilitation after reconstruction, there may be gaps in our understanding of the effectiveness of eccentric hamstring contractions in ACL rehabilitation,for rehabilitation after ACLR, progressive eccentric cycle training was not more clinically effective than concentric training (Giovanni Milandri, Sudesh Sivarasu, 2021). Addressing these gaps can provide valuable insights for providing rehabilitation protocols and enhancing outcomes for individuals recovering from ACL injury.
Overall, the background of the study highlights the importance of understanding the relationship between eccentric hamstring contraction and ACL grade 1 injury rehabilitation. The study aims to provide insights into how eccentric hamstring contraction may influence ACL grade 1 injury rehabilitation.
- THE OBJECTIVE OF THE STUDY
- To assess the effectiveness of eccentric hamstring contractions on changes in sports performance, using various testing methods, in the intervention group.
- To evaluate the impact of eccentric hamstring contractions on quality of life and psychological well-being in young male football players with non-contact grade 1 ACL injury.
- To compare sports performance outcomes between the intervention and control groups in young male football players with non-contact grade 1 ACL injury.
The overall aim of the study is to evaluate the impact of eccentric hamstring contractions on sports performance in young male football players with non-contact grade 1 ACL injuries hamstring exercises on sports performance among young male football players with non-contact grade 1 ACL injury in UAE. The participants recruited in the study will be randomly assigned to one of two intervention groups: a control arm (usual physiotherapy exercise will be given) and, an intervention Arm (custom-tailored eccentric hamstring exercises along with physiotherapy will be given). We assumed no interaction between the treatment arms.
Operational Definitions
- ACL - The anterior cruciate ligament (ACL) is one of 2 cruciate ligaments that aids in stabilizing the knee joint. It is a strong band made of connective tissue and collagenous fibers that originate from the anteromedial aspect of the intercondylar region of the tibial plateau and extends posterolaterally to attach to the medial aspect of the lateral femoral condyle, where there are two important landmarks; The lateral intercondylar ridge which defines the anterior boundary of the ACL, and the bifurcate ridge which separates the 2 ACL bundles(Evans J, 2023).
- Eccentric hamstring exercises - An eccentric strengthening exercise program for the hamstring muscles that can be performed during training can help prevent hamstring injuries in soccer players(Schache A, 2012).
- Nordic hamstring curl training (NHCT), a type of training based on eccentric contractions aimed at increasing hamstring muscle strength and performed on flat ground without requiring special equipment, has been accepted as a popular training method(Al Attar, 2017).
- Running, one of the most basic human motions, is characterized by a typical cyclic motion and an airborne phase involving projection of the body. Sprint running is recognized as the fastest mode of unaided human locomotion (Michiyoshi Ae, 2017).
Pain Categories:
- Mild: Pain intensity 1-3/10, occasional discomfort, no interference with daily tasks.
- Moderate: Pain intensity 4-6/10, noticeable during activities, some difficulty with strenuous movements.
- Severe: Pain intensity 7-10/10, significant pain at rest and with movement, difficulty with daily activities.
- Swelling Categories:
- Mild: Slight increase in size, no significant loss of motion, resolves with rest.
- Moderate: Noticeable swelling, some difficulty with knee movement, lasts several hours or days.
- Severe: Significant swelling, major restriction of movement, may require medical intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control Arm (conventional physiotherapy) | Active comparator | Other: ExercisesReceives conventional physiotherapy alone 1. Knee Straightening (Extension) 2. Knee Bend (Flexion): 3. Inner Range Quads 4. Straight Leg Raise 5. Lunge to Split Lunge 6. Single Leg Sit to Stand 7. Standing Hamstring Curls 8. Double/Single Leg Bridge 9. Side Lie Hip Abductions 10. Crab Walks 11. Forward Step Ups 12. Calf Raises. 13. Single Leg Balance 14. Clock Face Mini Squat 15. Arabesque Clock 16. Two-Legged Jump / Single-Legged Hop |
| Experimental Arm | Experimental | Other: ExercisesReceives both intervention exercises and conventional physiotherapy |
Who may qualify
- Ages
- 19 to 25 years
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- physician-diagnosed non-contact acute grade 1 ACL injury within the past 6 weeks will be invited from the selected clubs for participation in the trial. Participants who can perform full Range of Motion in the injured knee without pain will be included. Male football players between age 19-25 years old, currently playing in UAE, who speak English language and with physician-diagnosed non-contact grade 1 ACL injury will be included in the trial.
Key exclusion criteria (11 listed)
- • Players with contact ACL injuries.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Exercises1. Nordic hamstring curls 2. Seated leg curls 3. Prone leg curls 4. Knee Straightening (Extension) 5. Knee Bend (Flexion) 6. Inner Range Quads 7. Straight Leg Raise 8. Lunge to Split Lunge 9. Single Leg Sit to Stand 10. Standing Hamstring Curls 11. Double/Single Leg Bridge 12. Side Lie Hip Abductions 13. Crab Walks 14. Forward Step Ups 15. Calf Raises 16. Single Leg Balance 17. Clock Face Mini Squat 18. Arabesque Clock 19. Two-Legged Jump / Single-Legged Hop | Other | Control Arm (conventional physiotherapy), Experimental Arm |
Primary outcome
ACL Quality of Life (ACL-QOL) questionnaire
Time frame: first intervention day and 3 months
Description: The ACL-QOL is a self-administered scale composed of 32 items divided into 5 domains: symptoms and physical complaints (5 items), work-related concerns (4 items), recreational activity and sport participation or competition Each domain has a proportional value according to the number of questions and is assessed with a 100-mm visual analog scale. A higher score indicates a better QOL
1 secondary outcome
Sargent vertical jump test
Time frame: First day of intervention and at 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Background: PubMed 19204567Oliver GD, Dougherty CP. The razor curl: a functional approach to hamstring training. J Strength Cond Res. 2009 Mar;23(2):401-5. doi: 10.1519/JSC.0b013e31818f08d0.
- Background: PubMed 33555943Milandri G, Sivarasu S. A Randomized Controlled Trial of Eccentric Versus Concentric Cycling for Anterior Cruciate Ligament Reconstruction Rehabilitation. Am J Sports Med. 2021 Mar;49(3):626-636. doi: 10.1177/0363546520987566. Epub 2021 Feb 8.
- Background: PubMed 28391716Takahashi S, Okuwaki T. Epidemiological survey of anterior cruciate ligament injury in Japanese junior high school and high school athletes: cross-sectional study. Res Sports Med. 2017 Jul-Sep;25(3):266-276. doi: 10.1080/15438627.2017.1314290. Epub 2017 Apr 10.
- Individual participant dataSharing planned: No. As per the informed consent
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Anil John, PhD principal investigator
Lincoln University College
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Exercises in people with Grade 1 Anterior Cruciate Ligament Injury, run by Emirates Health Services (EHS) at 1 site in United Arab Emirates.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Arab Emirates. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
ACL Quality of Life (ACL-QOL) questionnaire (time frame: first intervention day and 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07115316, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.