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Healty VolunteersNCT07112534

This Study Explores Whether Static Stretching and Foam Rolling Intervention of the Calf (Dominant Leg) Can Improve Range of Motion and Balance Similarly to Treatments Applied to the Hamstring (Dominant Leg), Supporting the Concept of Myofascial Chains

A study testing Static stretching and Foam rolling in people with Healty Volunteers, run by Alberto Canzone at 1 site in Italy.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study explores the effects of static stretching (SS) and foam rolling (FR) on the knee's range of motion (ROM) and balance, with particular reference to their application to the calf muscles and their possible influence through the myofascial chain known as the superficial back line (SBL). Read more about this study

Who is it for?
Ages 20 to 40 yearsHealthy volunteers can take part
Conditions the study is for
Healty Volunteers
What is being tested?
Static stretching and Foam rolling
Could I receive a placebo?
No, everyone receives an active treatment
How many people
48 participants
Where
1 siteItaly
Study dates
15 Jan 2025to 15 Jun 2025
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 40 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • no lower limb injuries in the 6 months before the start of the study, and no musculoskeletal disorders were recruited for this study

Who cannot join

  • lower limbs injuries

Trial locations and contacts

1 site in 1 country.

Italy1 site
  • University of Palermo

    Palermo, Italy, 90144

Other trials in Italy

About this study

Official title: Static Stretching and Foam Rolling in the Calf Muscles vs Static Stretching and Foam Rolling in the Hamstrings: Effects on Knee ROM and Balance

This study explores the effects of static stretching (SS) and foam rolling (FR) on the knee's range of motion (ROM) and balance, with particular reference to their application to the calf muscles and their possible influence through the myofascial chain known as the superficial back line (SBL). Balance is an essential skill for maintaining an upright posture and avoiding Falls, especially in people with chronic conditions. The knee plays a crucial role in load-bearing and locomotion, and its function can be limited by reduced muscle flexibility, particularly of the rectus femoris. To counteract this, SS and FR are commonly used strategies to improve ROM and are frequently employed in sports and rehabilitation settings.

SS involves holding a muscle in an elongated position for a set period, while FR is a self-massage technique using a roller or massage bar that applies pressure to soft tissues through body weight. Both techniques have been shown to increase ROM, reduce muscle stiffness, and potentially improve athletic performance and recovery.

Read more

The study also discusses the concept of tensegrity, fascia, and myofascial chains, which explain how different body structures are biomechanically connected. Fascia is described as a tissue capable of transmitting mechanical forces throughout the body, forming a continuum that supports and connects muscles, bones, and other structures. Evidence shows that tension can be transmitted through fascial connections, influencing movement and posture far from the point of force application. The SBL, described by Myers, connects the calf muscles with the hamstrings and posterior structures, implying that interventions on the calf could affect knee mobility similarly to direct hamstrings treatment.

The research aimed to verify whether SS and FR protocols applied to the calves could produce similar benefits for knee ROM and balance as those applied to the hamstrings, based on their shared fascial connection. It also sought to compare the effectiveness of FR and SS, hypothesizing greater effects for FR due to its combined compression and stretching action.

A total of 48 healthy subjects aged 20-40 years, with no recent lower limb injuries, were recruited and divided into four groups: hamstring static stretching (SSH), calf static stretching (SSC), hamstring foam rolling (FRH), and calf foam rolling (FRC). The interventions were standardized in terms of duration and intensità: 3 sets of 1 minute each with moderate intensity perceived as 7/10 on a discomfort scale, performed only on the dominant leg. SS was performed using classic stretching positions, while FR involved rolling from the popliteal fossa to the insert points of the target muscles using a BLACROLL® foam roller.

Measurements included single-leg balance (SLB) test on a posturographic platform, knee ROM in flexion and extension using an inertial sensor, both before and 5 minutes after the intervention. Balance parameters analyzed were sway path length, sway ellipse surface, mean sway speed, and other center of pressure variables.

Statistical analysis involved repeated-measures ANOVA for parametric variables and non-parametric ANOVA for balance parameters, with appropriate post hoc tests. The significance level was set at p<0.05, and the effect size was assessed with partial eta squared.

This research provides insights into the effectiveness of targeting different muscle groups within the same myofascial chain for improving knee mobility and balance. The results are expected to clarify whether indirect treatments of the calf can replicate the effects of direct hamstring protocols and whether FR can outperform SS in terms of increasing knee ROM and improving postural control.

Being tested
Static stretching, Foam rolling
Keywords
Myofasial chains, Postural control, Balance, Range of motion

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Static stretchingOther

    Static stretching: 3 sets of 1 minute and 30 seconds of rest between sets

  • Foam rollingOther

    Foam rolling: 3 sets of 1 minute and 30 seconds of rest between sets

Study groups in NCT07112534
Study groupRoleWhat they receive
foam rolling of the calfOtherFoam rolling of the calf (dominante leg)
Receives: Other: Foam rolling
Static stretching of the calfOtherStatic stretching of the calf (dominant leg)
Receives: Other: Static stretching
foam rolling of the hamstringOtherfoam rolling of the hamstring (dominant leg)
Receives: Other: Foam rolling
Static stretching of the hamstringOtherStatic stretching of the hamstring (dominant leg)
Receives: Other: Static stretching

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Evaluation of static balance via a posturographic platform

    The single-leg balance (SLB) test used a freeMed® platform (50 Hz) with freeStep® software. Subjects stood comfortably, then balanced on the dominant leg, flexing the other backward, arms at hips for 10 s. Extracted: sway path lenght (mm), sway ellipse surface (mm2), sway mean speed (mm/s), sway path length/sway ellipse surface, X/Y-medium (mm), ∆X (mm), ∆Y (mm).

    Measured: Complex 1 hour to complete both intervention and measurements (acute effects)

  2. Assessment of knee flexion and extension range of motion using an inertial sensor

    Knee flexion ROM (º): prone on a couch, inertial sensor on medial malleolus, elastic at gluteals. Subjects flexed the dominant leg, heel to gluteus, head turned sideways, 3 reps; mean used. Knee extension ROM (º): supine with sensor, dominant leg on box, non-dominant extended; tibia actively extended upward, 3 reps, mean calculated.

    Measured: Complex 1 hour to complete both intervention and measurements (acute effects)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted8 Aug 2025
  2. Study start15 Jan 2025
  3. Primary completion28 Feb 2025
  4. Study completion15 Jun 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Factorial
Masking
Single blind
Who is masked
Participant
Enrolment
48 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07112534
Sponsor's protocol ID
60646-2025
Other IDs
PRIN 2022PZH8SX
Status last verified
Aug 2025
First submitted
21 Jul 2025
Last updated
8 Aug 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing Static stretching and Foam rolling in people with Healty Volunteers, run by Alberto Canzone at 1 site in Italy.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Evaluation of static balance via a posturographic platform (time frame: Complex 1 hour to complete both intervention and measurements (acute effects)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Aug 2025; AzTrials last refreshed its copy on 28 Oct 2026.

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