Social Anxiety Disorder (SAD)NCT07106840
Autism Traits in Adolescents With Social Anxiety Disorder: Associations With Parental Broader Autism Phenotype
An observational study of Social Anxiety Disorder (SAD) and Autistic Disorder, run by Ankara City Hospital Bilkent at 1 site in Turkey (Türkiye).
Trial summary
This observational study aims to examine autism-related traits in adolescents diagnosed with social anxiety disorder (SAD) and to evaluate their associations with broader autism phenotype (BAP) features in their parents. A total of 109 adolescents aged 11-17 and their parents were included. Read more about this study
- Who is it for?
- Ages 11 to 17 years
- Conditions the study is for
- Social Anxiety Disorder (SAD), Autistic Disorder
- How many people
- 109 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 11 Jan 2024to 1 Mar 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 11 to 17 years
- All sexes
- No healthy volunteers
- Child
Study population: This study included 109 adolescents aged 11-17 years diagnosed with Social Anxiety Disorder, along with their biological parents. The sample consisted of 87 females and 22 males. Participants were recruited prospectively from clinical outpatient settings.
Who may be able to join
- Adolescents aged 11-17 years diagnosed with Social Anxiety Disorder (SAB). Availability of at least one biological parent willing to participate. Ability to provide informed consent/assent.
Who cannot join
- Presence of intellectual disability or severe neurological disorder. Comorbid psychiatric diagnoses that could interfere with assessment (e.g., psychosis).
- Non-fluency in the language of assessment.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Identification of Autism Traits in Adolescents With Social Anxiety Disorder and Evaluation of Their Association With the Broader Autism Phenotype in Their Parents
This observational study aims to examine autism-related traits in adolescents diagnosed with social anxiety disorder (SAD) and to evaluate their associations with broader autism phenotype (BAP) features in their parents. A total of 109 adolescents aged 11-17 and their parents were included. Standardized scales were used to assess social anxiety severity and autism traits in adolescents, and BAP characteristics in parents.
Read the detailed description
Autism spectrum traits and social anxiety share clinical and cognitive features, particularly in the domains of social communication and interaction. These overlaps suggest that autistic traits may be present in adolescents diagnosed with social anxiety disorder (SAD), even in the absence of a formal autism diagnosis. Furthermore, the concept of the broader autism phenotype (BAP) suggests that subclinical autism-related features may be observed in parents of individuals with autism traits.
This study includes 109 adolescents (aged 11-17) diagnosed with SAD and their parents. The adolescents completed a standardized scale assessing social anxiety severity, while parents completed the Social Responsiveness Scale (SRS) for their children and the Autism Spectrum Quotient (AQ) to assess BAP characteristics in themselves. The study aimed to explore the associations between adolescents' autism-related traits and their social anxiety severity, and to evaluate how parental BAP scores (particularly fathers') may be associated with these traits.
Note: This study involved prospective recruitment and data collection; however, registration was completed retrospectively after the study was completed.
- Conditions
- Social Anxiety Disorder (SAD), Autistic Disorder
- Being tested
- No intervention (observational study)
- Keywords
- Phobia, Social, Anxiety, Autistic Disorder, Parents, Social Interaction
- Medical subject headings
- Phobia, Social, Autistic Disorder, Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No intervention (observational study)Other
This is an observational study with no intervention applied.
What is being measured
The primary outcome is the main question the study is designed to answer.
Social Anxiety Severity
Severity of social anxiety symptoms measured by the Social Anxiety Disorder Severity Scale - Child Form.
Measured: At baseline
Secondary outcomes (1)
Autism Traits in Adolescents
Autism spectrum traits in adolescents assessed by the Social Responsiveness Scale, completed by parents.
Measured: At baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Aug 2025
- Study start11 Jan 2024
- Primary completion10 Feb 2025
- Study completion1 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Social Anxiety Disorder (SAD)Studies of the same condition, open and under way.
- More trials run by Ankara City Hospital BilkentThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 109 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ankara City Hospital Bilkent
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Şermin Bilgen Ulgar, Ankara City Hospital Bilkent
- Investigators
- Şermin Bilgen Ulgar, Medical Doctor, Principal investigator, Ankara City Hospital Bilkent
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07106840
- Sponsor's protocol ID
- AnkaraCH_SAD_Autism_2025_01
- Other IDs
- E2-24-6099
- Status last verified
- Jul 2025
- First submitted
- 30 Jul 2025
- Last updated
- 6 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data will be shared upon reasonable request with qualified researchers, in accordance with ethical approvals and participant confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 6 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Identification of Autism Traits in Adolescents With Social Anxiety Disorder and Evaluation of Their Association With the Broader Autism Phenotype in Their Parents
- ClinicalTrials.gov ID
- NCT07106840
- Acronym / sponsor ID
- AnkaraCH_SAD_Autism_2025_01
- Conditions
- Social Anxiety Disorder (SAD), Autistic Disorder
- Keywords
- Phobia, Social, Anxiety, Autistic Disorder, Parents, Social Interaction
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 109 participants (actual)
- Lead sponsor
- Ankara City Hospital BilkentUniversity, hospital or other
- Study start
- 11 Jan 2024 (actual)
- Primary completion
- 10 Feb 2025 (actual)
- Study completion
- 1 Mar 2025 (actual)
- First posted
- 6 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to examine autism-related traits in adolescents diagnosed with social anxiety disorder (SAD) and to evaluate their associations with broader autism phenotype (BAP) features in their parents. A total of 109 adolescents aged 11-17 and their parents were included. Standardized scales were used to assess social anxiety severity and autism traits in adolescents, and BAP characteristics in parents.
Detailed description
Autism spectrum traits and social anxiety share clinical and cognitive features, particularly in the domains of social communication and interaction. These overlaps suggest that autistic traits may be present in adolescents diagnosed with social anxiety disorder (SAD), even in the absence of a formal autism diagnosis. Furthermore, the concept of the broader autism phenotype (BAP) suggests that subclinical autism-related features may be observed in parents of individuals with autism traits.
This study includes 109 adolescents (aged 11-17) diagnosed with SAD and their parents. The adolescents completed a standardized scale assessing social anxiety severity, while parents completed the Social Responsiveness Scale (SRS) for their children and the Autism Spectrum Quotient (AQ) to assess BAP characteristics in themselves. The study aimed to explore the associations between adolescents' autism-related traits and their social anxiety severity, and to evaluate how parental BAP scores (particularly fathers') may be associated with these traits.
Note: This study involved prospective recruitment and data collection; however, registration was completed retrospectively after the study was completed.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 11 to 17 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- This study included 109 adolescents aged 11-17 years diagnosed with Social Anxiety Disorder, along with their biological parents. The sample consisted of 87 females and 22 males. Participants were recruited prospectively from clinical outpatient settings.
Key inclusion criteria (1 listed)
- Adolescents aged 11-17 years diagnosed with Social Anxiety Disorder (SAB). Availability of at least one biological parent willing to participate. Ability to provide informed consent/assent.
Key exclusion criteria (2 listed)
- Presence of intellectual disability or severe neurological disorder. Comorbid psychiatric diagnoses that could interfere with assessment (e.g., psychosis).
- Non-fluency in the language of assessment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No intervention (observational study)This is an observational study with no intervention applied. | Other | – |
Primary outcome
Social Anxiety Severity
Time frame: At baseline
Severity of social anxiety symptoms measured by the Social Anxiety Disorder Severity Scale - Child Form.
1 secondary outcome
Autism Traits in Adolescents
Time frame: At baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Aug 2025.
- Individual participant dataSharing planned: Yes. Individual participant data will be shared upon reasonable request with qualified researchers, in accordance with ethical approvals and participant confidentiality.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Şermin Bilgen Ulgar, Medical Doctor principal investigator
Ankara City Hospital Bilkent
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Social Anxiety Disorder (SAD) and Autistic Disorder, run by Ankara City Hospital Bilkent at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Social Anxiety Severity (time frame: At baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2025.