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Emotional DisturbanceNCT07105137

AI-assisted GNW on Adolescent Emotional Distress

A study testing AI-GNW, NF-GNW and NWG in people with Emotional Disturbance and Emotional Regulation, run by Peking University at 1 site in China.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This cluster-randomized controlled trial aims to evaluate the efficacy of an AI-assisted Guided Narrative Writing (AI-GNW) in alleviating emotional distress among adolescents. Classes will be randomized in a 1:1:1 ratio to one of three arms-AI-GNW, a no-feedback GNW (NF-GNW), or a Neutral Writing Group (NWG)-and will… Read more about this study

Who is it for?
Ages 10 to 19 yearsHealthy volunteers can take part
What is being tested?
AI-GNW, NF-GNW and NWG
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
486 participants
Where
1 siteChina
Study dates
19 May 2025to 25 Oct 2025
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 10 to 19 years
  • All sexes
  • Healthy volunteers accepted
  • Child, Adult

Who may be able to join

  • Native speakers of Chinese who are proficient in reading and writing Chinese.
  • Signed a informed consent form and voluntarily agreed to participate.
  • Owns a smartphone, tablet, or similar electronic device and is able to complete the required questionnaires and writing tasks.

Who cannot join

  • Prior clinical diagnosis of schizophrenia or any other major psychiatric disorder.
  • Presence of severe cognitive impairment, language-expression difficulties, or any other condition that would impede writing ability.
  • Participation in another similar psychological intervention or psychotherapy within the past three months.
  • Inability to tolerate a group-based intervention setting due to personal health conditions (e.g., serious illness).
  • Unwillingness or inability to provide necessary cooperation or to sign the informed consent form.

Trial locations and contacts

1 site in 1 country.

China1 site
  • Peking University

    Haidian, Beijing Municipality, 100871

Other trials in China

About this study

Official title: Artificial Intelligence-Assisted Expressive Writing Intervention to Improve Adolescent Emotional Distress: A Cluster Randomized Controlled Trial

This cluster-randomized controlled trial aims to evaluate the efficacy of an AI-assisted Guided Narrative Writing (AI-GNW) in alleviating emotional distress among adolescents. Classes will be randomized in a 1:1:1 ratio to one of three arms-AI-GNW, a no-feedback GNW (NF-GNW), or a Neutral Writing Group (NWG)-and will complete a three-day writing intervention. On the first day, participants in both GNW conditions will recount a negative experience and reflect on their thoughts and feelings; on the second day, they will focus exclusively on the negative aspects of that experience; and on the third day, they will explore its positive dimensions. In contrast, NWG participants will objectively document their previous day's daily routine. After each session, those in the AI-GNW arm will receive individualized, AI-generated feedback, whereas NF-GNW participants will proceed without feedback.

Read the detailed description

Adolescent mental health, and in particular emotional distress, has emerged as a global public health challenge. A recent meta-analysis of 80,879 adolescents found that approximately 25.2 percent experienced clinically significant depression and 20.5 percent suffered from anxiety, with these emotional disturbances accounting for an estimated 45 percent of the total disease burden in this age group. In China, the situation is equally alarming: the 2022 Blue Book on National Depression reports that roughly half of all individuals diagnosed with an emotional disorder are school-aged, and as many as 41 percent have interrupted their studies as a result. Beyond inflicting serious harm on adolescents' physical and psychological well-being, persistent emotional distress undermines social engagement and academic performance, and may precipitate more severe psychopathology, such as major depression, anxiety disorders, or even suicidal behaviors, placing a heavy burden on families, communities, and the public health system. Thus, early and effective intervention is of paramount importance for improving youth mental health.

Schools represent a central arena in adolescents' daily lives and an ideal platform for delivering psychological interventions. In response to rising rates of youth emotional problems, the Chinese government has enacted a series of policies to bolster mental health education and intervention in schools. However, the vast size of China's adolescent population and the relative scarcity of professional resources mean that traditional one-to-one intervention models have limited reach when implemented at scale. Many schools lack sufficient numbers of qualified counselors, and non-specialist teachers often do not possess the training needed to deliver sustained, targeted support, resulting in modest and non-durable effects on students' emotional well-being.

Moreover, school-based intervention programs confront several practical challenges. First, the number of licensed school-psychology professionals remains inadequate in many regions, leaving schools unable to provide consistent, high-quality support. Second, a persistent mismatch between intervention demand and available resources makes it difficult to tailor services to individual students' needs, undermining the overall effectiveness of existing programs.

Among the array of psychological interventions, writing-based approaches have gained prominence for their simplicity, low cost, and ease of dissemination in group settings such as classrooms. Writing interventions typically guide participants to articulate their emotions and thoughts in writing for 20-30 minutes per day over 3-5 consecutive days, thereby fostering emotional processing, adaptive expression, and the construction of personal meaning. Meta-analytic evidence confirms that such interventions yield significant improvements in emotional symptoms and related psychophysiological outcomes, including sleep quality. In Chinese adolescent populations, guided narrative writing has been shown to reduce examination anxiety and to ameliorate symptoms of depression and anxiety. Nevertheless, conventional writing interventions often lack mechanisms for timely, individualized feedback, which can dampen participant engagement and undermine the longevity of treatment gains.

Against this backdrop, the integration of artificial intelligence (AI) offers promising new avenues for enhancing psychological interventions. Prior research indicates that interventions incorporating ongoing, process-oriented feedback and interactive dialogue outperform those that provide no feedback. Yet, in large-scale implementations, human-delivered feedback is constrained by finite personnel resources. By leveraging natural-language processing techniques, AI systems can automatically detect emotional and cognitive markers in written text and deliver personalized feedback at scale, thereby addressing a critical gap in current practice. Introducing AI-driven feedback into adolescent writing interventions thus holds considerable promise for improving outcomes in emotional distress.

Building on these insights, the present study will recruit approximately 450 adolescent students and-using classes as clusters-randomly assign them in equal proportions to one of three arms: an AI-feedback Guided Narrative Writing group (AI-GNW), a no-feedback Guided Narrative Writing group (NF-GNW), or a Neutral Writing Group (NWG). We will evaluate the impact of AI-assisted narrative writing on emotional distress, comparing the trajectories of change across these three conditions.

Being tested
AI-GNW, NF-GNW, NWG
Keywords
AI-assisted, Expressive writing, Adolesents, Emotional distress, Insomnia
Medical subject headings
Affective Symptoms, Emotional Regulation, Sleep Initiation and Maintenance Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • AI-GNWBehavioural

    This is a three-day writing intervention. Each session lasts 20 minutes. On the first day, participants in both GNW conditions will recount a negative experience and reflect on their thoughts and feelings; on the second day, they will focus exclusively on the negative aspects of that experience; and on the third day, they will explore its positive dimensions. AI-GNW participants would receive AI-generated feedback.

  • NF-GNWBehavioural

    guided narrative writing without feedbacks

  • NWGBehavioural

    In contrast, NWG participants will objectively document their previous day's daily routine.

Study groups in NCT07105137
Study groupRoleWhat they receive
AI-GNWExperimentalNot described
Receives: Behavioral: AI-GNW
NF-GNWActive comparatorNot described
Receives: Behavioral: NF-GNW
NWGSham comparatorNot described
Receives: Behavioral: NWG

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Revised Child Anxiety and Depression Scale (RCADS)

    RCADS is a 25-item scale that includes 15 items for general anxiety and 10 for depression, rated on a 4-point Likert scale (0 = never, 3 = always). Higher scores mean more severe emotional distress

    Measured: Baseline (day 0), post-intervention (day 4), and follow-ups at 1 (day 34), and 3 (day 64) months after the intervention.

Secondary outcomes (3)
  1. Non-Suicidal Self-Injury Assessment Tool (NSSI-AT)

    Only the severity dimension was measured in this trial.

    Measured: Baseline (day 0), post-intervention (day 4), and follow-ups at 1 (day 34), and 3 (day 64) months after the intervention.

  2. Suicidal Behaviors Questionnaire-Revised (SBQ-R)

    Measured: Baseline (day 0), post-intervention (day 4), and follow-ups at 1 (day 34), and 3 (day 64) months after the intervention.

  3. Chinese PTSD Symptom Scale (CPSS)

    Measured: Baseline (day 0), post-intervention (day 4), and follow-ups at 1 (day 34), and 3 (day 64) months after the intervention.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted5 Aug 2025
  2. Study start19 May 2025
  3. Primary completion25 Oct 2025
  4. Study completion25 Oct 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Parallel groups
Masking
Triple blind
Who is masked
Participant, Investigator, Outcomes assessor
Enrolment
486 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07105137
Sponsor's protocol ID
AI-assisted GNW
Status last verified
Jun 2026
First submitted
16 May 2025
Last updated
10 Jun 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: To protect participants' privacy, authors wishing to access the data should contact the corresponding author and provide a statistical analysis plan addressing a new research question. The study trial management group will discuss all requests.

Questions about this trial

What is this clinical trial studying?

A study testing AI-GNW, NF-GNW and NWG in people with Emotional Disturbance and Emotional Regulation, run by Peking University at 1 site in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 10 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Revised Child Anxiety and Depression Scale (RCADS) (time frame: Baseline (day 0), post-intervention (day 4), and follow-ups at 1 (day 34), and 3 (day 64) months after the intervention.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Jun 2026.

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