Heart FailureHeFRANCT07100561
30 Days and 90 Days Heart Failure Re-Admission at Komfo Anokye Teaching Hospital
A study testing Extensive post discharge counselling and phone-based follow up in people with Heart Failure, run by Komfo Anokye Teaching Hospital at 1 site in Ghana.
Trial summary
In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Heart Failure
- What is being tested?
- Extensive post discharge counselling and phone-based follow up
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 220 participants
- Where
- 1 siteGhana
- Study dates
- 14 Jul 2025to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- · Adults Aged 18 years and above
- Diagnosed with heart failure
- NYHA Class II-IV
- Informed consent
Who cannot join
- · NHYA class I
- Patients who do not have access to a mobile phone
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Ghana1 site, 1 recruiting
- Recruiting
Komfo Anokye Teaching Hospital
Kumasi, Ashanti Region
Solomon Gyabaah, +233265763129, solomongyabaah53@gmail.com
About this study
Official title: Extensive Post-discharge Counselling and Phone-based Follow-up Intervention to Reduce Heart Failure Readmission- A Pilot Randomized Control Trial
In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. This may be due to the underutilization of these evidence-based therapies or a lack of proper follow-up on these patients. Recurrent hospital admission is an independent predictor of death in heart failure. Strategies aimed at providing increased support at discharge and effective follow-up may be associated with lower readmission risk. This study aims to assess the effect of extensive post-discharge counselling and effective phone-based follow-up on the 30-day and 90-day heart failure readmission rate at a tertiary hospital in Ghana. This is a single-centre, pilot randomised controlled trial of heart failure patients admitted to the Komfo Anokye Teaching Hospital
- Conditions
- Heart Failure
- Being tested
- Extensive post discharge counselling and phone-based follow up
- Keywords
- heart failure readmission, phone-based follow up, extensive post discharge counseling, pilot randomized control trial
- Medical subject headings
- Heart Failure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Extensive post discharge counselling and phone-based follow upOther
Counselling by their attending physicians plus Extensive post-discharge counselling from a study doctor/pharmacist/a trained nurse and telephone follow-ups in addition to their normal outpatient reviews. The telephone follow-ups will be weekly for the first 30 days and then 4 weekly till day 90.
| Study group | Role | What they receive |
|---|---|---|
| control/Usual Care | No intervention | The usual care (counselling by their attending physicians and their normal outpatient reviews). |
| intervention arm | Experimental | Not described Receives: Other: Extensive post discharge counselling and phone-based follow up |
What is being measured
The primary outcome is the main question the study is designed to answer.
the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization
the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization
Measured: 90 days
Secondary outcomes (4)
1. Readmission rate of heart failure patients on guideline-directed heart failure medications
The readmission rate of heart failure patients on guideline-directed medical therapy (GDMT) will be compared to those who are not on GDMT.
Measured: 90days
Quality of life of the heart failure patients at 90 days
Quality of life at 90 days will be measured using the Kansas City Cardiomyopathy Questionnaire (KCCQ).
Measured: 90days
All-cause mortality within 30 and 90 days
. Assessing all-cause mortality will involve tracking total deaths from any reason within a population over the 90-day follow-up
Measured: 90 days
Caregiver burden in heart failure management
Caregiver burden will be assessed using the standard tool "Caregiver Burden Questionnaire - Heart Failure Version 3.0 (CBQ-HF)
Measured: 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Aug 2025
- Study start14 Jul 2025
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Heart FailureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 220 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Komfo Anokye Teaching Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07100561
- Sponsor's protocol ID
- KATHIRB/AP/031/25
- Acronym
- HeFRA
- Status last verified
- Aug 2026
- First submitted
- 1 Jul 2025
- Last updated
- 10 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 10 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Extensive Post-discharge Counselling and Phone-based Follow-up Intervention to Reduce Heart Failure Readmission- A Pilot Randomized Control Trial
- ClinicalTrials.gov ID
- NCT07100561
- Acronym / sponsor ID
- HeFRA / KATHIRB/AP/031/25
- Conditions
- Heart Failure
- Keywords
- heart failure readmission, phone-based follow up, extensive post discharge counseling, pilot randomized control trial
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 220 participants (estimated)
- Lead sponsor
- Komfo Anokye Teaching HospitalUniversity, hospital or other
- Study start
- 14 Jul 2025 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 3 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. This may be due to the underutilization of these evidence-based therapies or a lack of proper follow-up on these patients. Recurrent hospital admission is an independent predictor of death in heart failure. Strategies aimed at providing increased support at discharge and effective follow-up may be associated with lower readmission risk. This study aims to assess the effect of extensive post-discharge counselling and effective phone-based follow-up on the 30-day and 90-day heart failure readmission rate at a tertiary hospital in Ghana. This is a single-centre, pilot randomised controlled trial of heart failure patients admitted to the Komfo Anokye Teaching Hospital
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| control/Usual Care | No intervention | –The usual care (counselling by their attending physicians and their normal outpatient reviews). |
| intervention arm | Experimental | Other: Extensive post discharge counselling and phone-based follow up |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- · Adults Aged 18 years and above
Key exclusion criteria (2 listed)
- · NHYA class I
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Extensive post discharge counselling and phone-based follow upCounselling by their attending physicians plus Extensive post-discharge counselling from a study doctor/pharmacist/a trained nurse and telephone follow-ups in addition to their normal outpatient reviews. The telephone follow-ups will be weekly for the first 30 days and then 4 weekly till day 90. | Other | intervention arm |
Primary outcome
the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization
Time frame: 90 days
the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization
4 secondary outcomes
1. Readmission rate of heart failure patients on guideline-directed heart failure medications
Time frame: 90days
Quality of life of the heart failure patients at 90 days
Time frame: 90days
All-cause mortality within 30 and 90 days
Time frame: 90 days
Caregiver burden in heart failure management
Time frame: 30 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Extensive post discharge counselling and phone-based follow up in people with Heart Failure, run by Komfo Anokye Teaching Hospital at 1 site in Ghana.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Ghana. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact SOLOMON GYABAAH (+233265763129, solomongyabaah53@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization (time frame: 90 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Sep 2026.