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UnemploymentNCT07097376

Evaluating the Efficacy of a Vocational Counseling Intervention to Improve Occupational Functioning and Employment Quality Among Veterans With Mental Health and Substance Use Disorders

A study testing Purposeful Pathways and Transitional Work in people with Unemployment, run by VA Office of Research and Development at 3 sites in United States.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Veterans living with mental health and substance use conditions are at risk of unemployment, which leads to significant health-related consequences. Though the Veterans Health Administration offers numerous vocational rehabilitation programs to address unemployment, they are not uniformly effective for everyone who… Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Unemployment
What is being tested?
Purposeful Pathways and Transitional Work
Could I receive a placebo?
No, everyone receives an active treatment
How many people
254 participants
Where
3 sitesUnited States
Study dates
1 Sep 2026to 31 Mar 2031
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • enrolled in VHA TW at one of the three VA recruitment sites
  • be unemployed
  • report interest/intention to return to paid work within the upcoming three years
  • presence of a psychiatric disorder as indicated by documented ICD-10 diagnosis (mental health disorder and/or substance use disorder) addressed in an encounter at VHA within the 24 months preceding study enrollment
  • willing to participate in weekly vocational counseling sessions

Who cannot join

  • report a plan to remain unemployed during the upcoming 12 months
  • report plans to retire within the next 12 months
  • be currently retired
  • be a full-time student
  • enrolled in Supported Employment
  • experiencing significantly elevated mental health symptoms as indicated by a score greater than 26 on the Symptom Checklist-6 (SCL-648)
  • have a guardian or conservator

Trial locations and contacts

3 sites in 1 country. Contact the study team or a site near you to ask about taking part.

Brian J Stevenson, PhD contact

(718) 687-3919

Brian.Stevenson4@va.gov

United States3 sites, 3 recruiting
  • VA Bedford HealthCare System, Bedford, MA

    Bedford, Massachusetts, 01730-1114

    Brian J Stevenson, PhD, (718) 687-3919, Brian.Stevenson4@va.gov

    Brian J Stevenson, PhD

    Not yet recruiting
  • VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX

    Dallas, Texas, 75216-7167

    James LePage, PhD, 214-857-0240, james.lepage@va.gov

    Not yet recruiting
  • Edward Hines Jr. VA Hospital, Hines, IL

    Hines, Illinois, 60141-3030

    Matthew Sprong, PhD, 815-993-8724, matthew.sprong@va.gov

    Recruiting

Other trials in United States

About this study

Veterans living with mental health and substance use conditions are at risk of unemployment, which leads to significant health-related consequences. Though the Veterans Health Administration offers numerous vocational rehabilitation programs to address unemployment, they are not uniformly effective for everyone who participates. This project will test a new model for addressing Veteran unemployment. This new model adds career development services (a vocational counseling program called Purposeful Pathways) to a standard model of vocational rehabilitation (a program called Transitional Work [TW]). The investigators will test if adding Purposeful Pathways to TW leads to more Veterans working in quality jobs as well as better quality of life, reduced mental health symptoms, and reduced substance use. This project fills a critical need in advancing research and practice aimed at reducing Veteran unemployment; thereby preventing consequences to Veteran's economic, social, and health related functioning and well-being.

The investigators will conduct a phase II, multi-site, RCT comparing Purposeful Pathways + TW (n=127) to TW alone (n=127) among Veterans participating in TW at VA Bedford, VA Hines, and VA North Texas. Aim 1: Evaluate the efficacy of Purposeful Pathways for improving occupational functioning (primary outcome). Hypothesis: Purposeful Pathways + TW, compared to TW only, will improve occupational functioning. Aim 2: Evaluate the efficacy of Purposeful Pathways for improving quality of life, and reducing mental health symptoms and substance use (secondary outcomes). Hypothesis: Purposeful Pathways + TW, compared to TW only, will improve quality of life, and reduce mental health symptoms and substance use. Aim 3 (Exploratory): Explore whether occupational functioning (competitive employment attainment) in the Purposeful Pathways + TW group is mediated by vocational identity, work hope, self-regulation, and/or employment motivation, key factors central to the Purposeful Pathways intervention.

Read the detailed description

The investigators will conduct a multi-site efficacy RCT comparing Purposeful Pathways + transitional work (TW) (n=127) to TW alone (n=127) with sites at VA Bedford (Bedford, MA), VA Hines (Chicago, IL), and VA North Texas (Dallas, TX). The proposed project will allow us to evaluate the efficacy of Purposeful Pathways as an augmentation to TW for improving the primary outcome of occupational functioning, as well as downstream improvements in secondary outcomes of quality of life, mental health, and substance use. The investigators will also explore whether occupational functioning outcomes in the Purposeful Pathways + TW group are mediated by the factors proposed by the underlying theoretical model for Purposeful Pathways.

Aim 1: Evaluate the efficacy of Purposeful Pathways for improving occupational functioning (primary outcomes) Hypothesis 1a-e: Purposeful Pathways + TW, compared to TW only, will improve occupational functioning at a 12-month follow-up as evidenced by (1a) rates of competitive employment, (1b) hours worked, (1c) income earned, (1d) career adaptabilities (Career Adapt-Abilities Scale), and (1e) meaningful employment (Work as Meaning Inventory-Positive Meaning Subscale).

Aim 2: Evaluate the efficacy of Purposeful Pathways for improving quality of life, and reducing mental health symptoms and substance use (secondary outcomes) Hypothesis 2a-c: Purposeful Pathways + TW, compared to TW only, will improve (2a) quality of life (Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form), and reduce (2b) mental health symptoms (Patient Health Questionnaire) and (2c) substance use (Tobacco, Alcohol, Prescription medications, and other Substance tool) at a 12-month follow-up

Aim 3 (Exploratory): Explore whether occupational functioning (competitive employment attainment) in the Purposeful Pathways + TW group is mediated by vocational identity, work hope, self-regulation, and/or employment motivation, key factors central to the Purposeful Pathways intervention.

The study intervention is a behavioral intervention. Purposeful Pathways is a manualized, vocational counseling intervention based on a Veteran-centered, recovery-oriented approach. The overarching target of the intervention is to increase motivation to pursue meaningful employment goals by enhancing vocational identity/positive vocational self-appraisals, increasing work hope (goals, pathways, and self-efficacy), and promoting employment-related self-regulation skills. The table below provides an overview of the specific treatment elements associated with each of the four core components: 1) career/identity exploration, 2) goal setting/planning, 3) job-search skill building, and 4) self-regulation skill building. The Purposeful Pathways intervention will be provided over 12 weeks by a master's level clinician affiliated with their respective (Bedford, Hines, of North Texas) vocational rehabilitation program. Sessions will be provided in person or through the VHA telehealth services platform (VVC).

All participants will complete the following surveys/questionnaires.

Demographics. The investigators will gather basic demographic information including age, gender, race, level of education, service-connected percentage, service connected condition, receipt of disability pensions, housing stability, and history of substance abuse and mental health diagnoses.

Competitive employment. The investigators will ask whether a Veteran has been competitively employed at any point over the previous month. In line with other RCT research, the investigators define competitive employment as "a non-sheltered job earning salary, wages, or commission, excluding military drill and transient cash-based jobs, such as yard work, babysitting, and manual day labor." (p. 318). For those employed, the investigators will also ask for job title, industry, and company names.

Weeks/hours worked. Among those who have worked in a competitive job, the investigators will ask about the number of days/weeks worked over the past month, as well as the number of hours worked.

Income earned. Among those who have worked in a competitive job, the investigators will ask for the participants' hourly wage.

Career-related adaptability skills. The Career Adapt-Abilities Scale (CAAS) will be utilized to measure one's level of career adaptability, a commonly used measure of ability and skill for navigating long-term career advancement. This is a 24-item measure that is grouped into four different subscales that capture total adaptability along with four dimensions: concern, control, curiosity, and confidence. Respondents are asked to rate how strongly they have developed each of these strengths using a 5-point Likert type scale. Responses range from 5 ("Strongest") to 1 ("Not strong").

Meaningful employment. The Positive Meaning Scale of the Work as Meaning Inventory (WAMI) will be used to measure the degree to which someone perceives their work as meaningful. The Positive Meaning scale consists of 4 items answered on a 7-point scale ranging from 1 (strongly disagree) to 7 (strongly agree). Higher scores represent higher levels of meaningful work. This scale has been used extensively in the vocational literature and has demonstrated consistent reliability and validity, including with Veterans with co-occurring conditions.

Job-Searching Behavior. The Job-Search Intensity Scale (JSIS) will be utilized to assess the level of time one spent on various job-search activities. This nine-item measure asks respondents about the following job-search activities: preparing/revising resume, reading classified/help. wanted advertisements, looking for jobs on the Internet, talking with friends/relatives about job leads, speaking with previous employers or business acquaintances about job leads, contacting employment agencies, making inquiries to prospective employers, sending out application letters, and preparing and going on job interviews. Responses to each activity are measured on a 5-point, Likert-type scale to assess the amount of time spent on each activity. Possible scores for each item range from 1 ("No time at all") to 5 ("Very much time").

Quality of life. The Quality of Life Enjoyment and Satisfaction Questionnaire - Short Form (Q-LES-Q - SF) will be used as a measure of general psychiatric functioning. The Q-LES-Q - SF is a 16 item self-report measure of perceived functioning and is one of the most widely used outcomes measures in psychiatric research.

Mental health: The Patient Health Questionnaire-9 (PHQ-9) is a 9-item measure of common mental health symptoms associated with depression. It is a widely used and available inventory in VHA with good validity and reliability.

Substance use. Substance use outcomes include frequency, quantity, and severity of substance use, and will be measured with the Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) tool, which is used within the National Institute on Drug Abuse (NIDA) clinical trials network.

Vocational identity. The Vocational Identity Scale (VIS) will measure the extent to which an individual possesses a clear and stable understanding of his or her goals, interests, and talents as related to vocational decisions. The VIS consists of 18 true or false items that asks respondents to identify whether the statement is mostly "True" or mostly "False." Higher scores indicate more crystallized vocational identity. The VIS is extensively used in vocational psychology literature and has undergone psychometric analysis demonstrating validity and reliability, and has been used in studies with Veterans and those with psychiatric disorders.

Work hope. The Work Beliefs Scale (WBS) will be utilized to measure work hope. This is a 24-item measure on a seven-point scale ranging from "Strongly disagree" to "strongly agree." Respondents are asked to rate their level of agreement on various items empirically related to work hope (having a goal, having a plan to reach goal, and having self-efficacy to pursue one's goal). Validity and reliability among individuals with significant psychosocial barriers have been established.

Self-regulation. The Short Self-Regulation Questionnaire (SSRQ) will be used to measure self-regulation skills. This 31-item self-report measures asks respondents to respond to items on a 5 point Likert type scale ranging from strongly disagree to strongly agree. The measure demonstrated construct validity and demonstrated high internal consistency among Veterans with co-occurring conditions.

Employment motivation. The Importance of Obtaining Preferred Position (IOPP) will be used to measure motivational attitudes to attain preferred employment. This is a 5-item measure on a five-point scale ranging from "Not important" to "Very Important." This scale has been validated and has been used widely in vocational literatures as an measure of motivational commitment to employment among individuals who are unemployed.

Client satisfaction. The Client Satisfaction Questionnaire-8 (CSQ-8) will be used to measure satisfaction, perceived quality, and effectiveness of treatment. This self-report questionnaire consists of eight items, scored 1 to 4, with higher scores indicating higher satisfaction with treatment. The CSQ-8 has been used in mental health and other health centers and has acceptable internal consistency.

Exit interviews. The investigators will randomly ask 30 Veterans participating in the intervention arm to complete a brief qualitative exit interview (15-minutes) at 12-week treatment end. These semi-structured, open-ended interviews will take place via phone, VVC, or in-person depending on Veteran's preference. Questions will assess barriers and facilitators of treatment engagement (e.g., Describe how the timing of the intervention fit into your day/week and overall recovery. Would you recommend the intervention earlier or later in your recovery? Would you recommend the intervention as in-person or virtual? Were there issues being able to attend your appointments? Did you received any feedback from your TW counselor or workplace supervisor about attending appointments?). Interviews will be recorded via VA-approved recording technologies and will be transcribed by a VA-approved transcription service.

Conditions
Unemployment
Being tested
Purposeful Pathways, Transitional Work
Keywords
rehabilitation, vocational

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Purposeful PathwaysBehavioural

    Purposeful Pathways is a manualized intervention to assist Veterans in aspiring and pursuing meaningful employment. Purposeful Pathways is an individual counseling protocol delivered weekly for up to 12 sessions (50 minutes per session) focused on career exploration, goal clarity, job-searching, and self-regulation.

  • Transitional WorkOther

    Also called CWT

    Provides individuals with immediate access to a non-competitive, paid job contracted by the VA. Positions are typically housed within a VA hospital (e.g., housekeeping, grounds, kitchens, and construction), but are sometimes located in the community. TW is time-limited. TW is staffed by vocational rehabilitation specialists (VRS).

Study groups in NCT07097376
Study groupRoleWhat they receive
Purposeful PathwaysExperimentalParticipants in this arm will receive treatment as usual, which is the transitional work intervention, as well as the Purposeful Pathways intervention
Receives: Behavioral: Purposeful Pathways; Other: Transitional Work
Treatment as usualActive comparatorParticipants in this arm will receive treatment as usual, which is the transitional work intervention.
Receives: Other: Transitional Work

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Number of Participants with Competitive Employment

    Number of participants who were competitively employed at any point over the previous month. We define competitive employment as a non-sheltered job that earns salary, wages, or commission, excluding military drill and transient cash-based jobs, such as yard work, babysitting, and manual day labor.

    Measured: through study completion, an average of 15 months

  2. Number of days worked

    The number of days worked in competitive employment over the past month

    Measured: through study completion, an average of 15 months

  3. Total hours worked

    The number of hours worked in competitive employment during previous month

    Measured: through study completion, an average of 15 months

  4. Income earned

    Total wages from competitive employment earned over the past month

    Measured: through study completion, an average of 15 months

  5. Career Adapt-Ability Scale

    One's functional abilities/strengths to successfully manage career-related tasks. Possible scores range from 24 - 120, with greater scores indicating greater career adaptability functioning.

    Measured: through study completion, an average of 15 months

  6. Positive Meaning Scale of the Work as Meaning Inventory

    Degree to which someone perceives their work as meaningful. Scores range from 4 - 28, with higher scores representing greater levels of meaningful work.

    Measured: through study completion, an average of 15 months

Secondary outcomes (10)
  1. Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form

    A self-report measure of perceived functioning. Scores range from 14 - 70 with higher scores indicating greater perceived functioning

    Measured: through study completion, an average of 15 months

  2. Patient Health Questionnaire-9

    Mental health symptom inventory. Responses range from 0 - 27, with greater scores indicating more severe mental health symptoms.

    Measured: through study completion, an average of 15 months

  3. Alcohol misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess alcohol misuse in the past three months. This scale consists of four Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 4, with greater scores indicating greater alcohol misuse.

    Measured: through study completion, an average of 15 months

  4. Marijuana misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess marijuana misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater marijuana misuse.

    Measured: through study completion, an average of 15 months

  5. Cocaine, crack, or methamphetamine misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess cocaine, crack, or methamphetamine misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater cocaine, crack, or methamphetamine misuse.

    Measured: through study completion, an average of 15 months

  6. Heroin misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess heroin misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater heroin misuse.

    Measured: through study completion, an average of 15 months

  7. Prescription opiate misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess prescription opiate misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater prescription opiate misuse.

    Measured: through study completion, an average of 15 months

  8. Medication for anxiety or sleep misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess medication for anxiety or sleep misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater medication for anxiety or sleep misuse.

    Measured: through study completion, an average of 15 months

  9. Medication for ADHD misuse

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess medication for ADHD misuse in the past three months. This scale consists of three Yes or No items (Yes = 1 and No = 0). Scores range from 0 - 3, with greater scores indicating greater medication for ADHD misuse.

    Measured: through study completion, an average of 15 months

  10. Other illegal or recreational drug use

    The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool Part 2 will assess any other illegal or recreational drug (for example, ecstasy/molly, GHB, poppers, LSD, mushrooms, special K, bath salts, synthetic marijuana ('spice'),whip-its, etc.) in the past three months. This is a single item Yes or No question (Yes = 1 and No = 0). Scores range from 0 - 1, with greater scores indicating use of other illegal or recreational drugs.

    Measured: through study completion, an average of 15 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted31 Jul 2025
  2. Study start1 Sep 2026
  3. Primary completion1 Oct 2030 (estimated)
  4. Study completion31 Mar 2031 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Participants will be randomly assigned to either a treatment as usual condition or to receive treatment as usual along with the additional intervention of Purposeful Pathways.
Masking
None (open label)
Enrolment
254 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07097376
Sponsor's protocol ID
RRD4-001-24W
Status last verified
Sep 2026
First submitted
16 Jul 2025
Last updated
9 Sep 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Purposeful Pathways and Transitional Work in people with Unemployment, run by VA Office of Research and Development at 3 sites in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 3 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Brian J Stevenson, PhD ((718) 687-3919, Brian.Stevenson4@va.gov), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Number of Participants with Competitive Employment (time frame: through study completion, an average of 15 months). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.

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