Tibial Meniscus TearsNCT07089316
Preoperative MRI and Radiographic Parameters in Medial Meniscus Root Tears and Repair Outcomes
An observational study of Tibial Meniscus Tears, run by Karadeniz Technical University at 1 site in Turkey (Türkiye).
Trial summary
This retrospective observational study aims to investigate whether specific preoperative magnetic resonance imaging (MRI) and radiographic parameters are associated with medial meniscus posterior root tears (MMPRT), and whether these parameters have predictive value for mid-term clinical and radiographic outcomes… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Tibial Meniscus Tears
- How many people
- 128 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2025to 15 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population includes adult patients diagnosed with medial meniscus posterior root tear (MMPRT) who underwent arthroscopic repair at Karadeniz Technical University Farabi Hospital between 2020 and 2024, as well as control patients without meniscus tears who had knee MRI and standing radiographs available in the same period. Controls were matched to the MMPRT group based on age, BMI, and mechanical axis distribution to minimize confounding.
Who may be able to join
- Patients aged 18 years or older
- Arthroscopically confirmed medial meniscus posterior root tear (MMPRT) diagnosis
- Availability of preoperative knee MRI and standing long-leg radiographs
- Minimum 24-month clinical and radiographic follow-up
Who cannot join
- Lateral meniscus tear
- Kellgren-Lawrence grade 3 or higher knee osteoarthritis
- Advanced ligament injuries
- History of previous knee surgery, osteotomy, or arthroplasty
- Poor imaging quality
- Mechanical axis deformities (varus or valgus alignment)
- Follow-up period less than 24 months
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Karadeniz Technical University, Orthopedic and Traumatology Department
Trabzon
About this study
Official title: Preoperative MRI and Radiographic Parameters Are Associated With Medial Meniscus Posterior Root Tears and Predict Mid-Term Clinical and Radiographic Outcomes After Repair
This retrospective observational study aims to investigate whether specific preoperative magnetic resonance imaging (MRI) and radiographic parameters are associated with medial meniscus posterior root tears (MMPRT), and whether these parameters have predictive value for mid-term clinical and radiographic outcomes after arthroscopic repair.
Patients with arthroscopically confirmed MMPRT treated between 2020 and 2024 are evaluated based on their preoperative MRI and standing knee radiographs. Imaging parameters of interest include medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology. Clinical outcomes are assessed using standardized scoring systems. The study aims to identify imaging-based anatomical risk factors to improve diagnosis, patient selection, and prognosis following MMPRT repair.
Read the detailed description
This retrospective observational study investigates the role of specific preoperative MRI and radiographic parameters in the diagnosis and prognosis of medial meniscus posterior root tears (MMPRT). Conducted at the Department of Orthopaedics and Traumatology, Karadeniz Technical University Farabi Hospital, the study aims to clarify whether morphologic imaging findings-such as medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology-are associated with the presence of MMPRT and influence postoperative outcomes following arthroscopic repair.
All imaging measurements were performed using standardized techniques on MRI and radiographs obtained prior to surgery. Parameters were assessed by two independent orthopedic surgeons on separate occasions to evaluate interobserver reliability. A matched control group of patients without meniscal pathology was formed to strengthen the comparative analysis and support the identification of risk factors.
By analyzing a wide range of anatomic features on imaging, this study seeks to enhance early diagnostic accuracy, improve patient selection for surgical repair, and refine prognostic counseling. The findings are expected to contribute to the development of objective, imaging-based indicators that can guide clinical decision-making and predict mid-term clinical and radiographic outcomes after MMPRT repair.
- Conditions
- Tibial Meniscus Tears
- Keywords
- Menisci, Tibial, Arthroscopy, Magnetic Resonance Imaging
- Medical subject headings
- Tibial Meniscus Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| MMPRT Patients | Patients with medial meniscus posterior root tears undergoing arthroscopic repair. | |
| Control Patients | Patients without meniscus tears, matched by age, BMI, and mechanical axis. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Medial Tibial Slope
Measured in degrees (°) on sagittal MRI. It is the angle between the tangent to the medial tibial plateau and the anatomical axis of the proximal tibia, drawn using a line connecting the anterior and posterior cortices of the plateau.
Measured: Preoperative MRI assessment
Medial Meniscus Extrusion
Measured in millimeters (mm) on coronal MRI. Defined as the distance from the outer margin of the medial meniscus to the edge of the tibial plateau
Measured: Preoperative MRI assessment
Tibial Plateau Depth
Measured in millimeters (mm) on sagittal MRI. It is the perpendicular depth from the deepest point of the medial tibial plateau concavity to a reference line connecting the anterior and posterior cortical rims.
Measured: Preoperative MRI assessment
Intercondylar Notch Width
Measured in millimeters (mm) on axial MRI images. Width of the intercondylar notch at the level of the popliteal groove.
Measured: Preoperative MRI assessment
Intercondylar Distance
Measured in millimeters (mm) on axial MRI. The distance between the outer surfaces of the medial and lateral femoral condyles at the level of the intercondylar notch.
Measured: Preoperative MRI assessment
Medial Femoral Condyle Angle
Measured in degrees (°) on sagittal MRI. It is the angle between the femoral anatomical axis and the curvature of the medial femoral condyle.
Measured: Preoperative MRI assessment
Notch Width Index (ICNW/ICD Ratio)
A unitless ratio obtained by dividing the intercondylar notch width by the intercondylar distance on axial MRI at the level of the popliteal groove.
Measured: Preoperative MRI assessment
Notch Shape
Morphological classification based on axial MRI. The intercondylar notch is categorized into A-type, U-type, or W-type based on its geometric configuration.
Measured: Preoperative MRI assessment
Presence of Osteophyte (Spur)
Binary variable (Yes/No) indicating the presence of an osteophyte at the intercondylar notch on axial or sagittal MRI.
Measured: Preoperative MRI assessment
Medial Femoral Condyle Width (MFCW)
Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.
Measured: Preoperative MRI assessment
Medial Tibial Plateau Width (MTPW)
Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.
Measured: Preoperative MRI assessment
MFCW/MTPW Ratio
Unitless ratio calculated by dividing medial femoral condyle width (MFCW) by medial tibial plateau width (MTPW) on coronal MRI.
Measured: Preoperative MRI assessment
Medial Femoral Condyle Distal Offset Distance
Measured in millimeters (mm) on sagittal MRI at the level of the medial femoral condyle midpoint (defined on coronal MRI) as the perpendicular distance from the intercondylar axis to the most distal point of the condyle.
Measured: Preoperative MRI
Medial Femoral Condyle Posterior Offset Distance
Measured in millimeters (mm) on the same sagittal MRI slice as the distal offset, defined as the distance from the intercondylar axis to the most posterior point of the condyle.
Measured: Preoperative MRI
MFC Distal / Posterior Offset Ratio
A unitless ratio calculated by dividing the medial femoral condyle distal offset distance by its posterior offset distance on sagittal MRI.
Measured: Preoperative MRI
Secondary outcomes (5)
International Knee Documentation Committee (IKDC) Score
Scored from 0 to 100, this subjective assessment evaluates knee symptoms, function, and ability to engage in sports activities. Higher scores indicate better outcomes.
Measured: Preoperative and minimum 24-month postoperative follow-up
Lysholm Knee Score
Scored from 0 to 100, this questionnaire evaluates limping, support, locking, pain, swelling, stair climbing, and squatting. Higher scores indicate better knee function.
Measured: Preoperative and minimum 24-month postoperative follow-up
Tegner Activity Scale
Activity level is rated on a scale from 0 (disability) to 10 (elite sports). Assesses the return to daily or sports-related physical activity.
Measured: Preoperative and minimum 24-month postoperative follow-up
Kellgren-Lawrence Grade Progression
Graded on a 0-4 scale, this radiographic classification evaluates the severity of osteoarthritis. Progression indicates worsening joint degeneration.
Measured: Preoperative and minimum 24-month postoperative radiographs
Medial Joint Space Width (JSW)
Measured in millimeters (mm) on standing AP radiographs as the minimum vertical distance between the medial femoral condyle and tibial plateau. Reflects cartilage loss or joint space narrowing.
Measured: Preoperative and minimum 24-month postoperative radiographs
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jul 2025
- Study start1 Jan 2025
- Primary completion1 Jun 2026
- Study completion15 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tibial Meniscus TearsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 128 participants (actual)
Sponsor and investigators
- Lead sponsor
- Karadeniz Technical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fevzi Gurkan Aslan, Karadeniz Technical University
- Investigators
- Fevzi Gurkan Aslan, M.D., Principal investigator, Karadeniz Technical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07089316
- Sponsor's protocol ID
- 24237859467
- Status last verified
- Mar 2026
- First submitted
- 6 Jul 2025
- Last updated
- 29 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: No individual participant data (IPD) will be shared for this study. Only aggregate results and statistical analyses will be published to protect patient confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Preoperative MRI and Radiographic Parameters Are Associated With Medial Meniscus Posterior Root Tears and Predict Mid-Term Clinical and Radiographic Outcomes After Repair
- ClinicalTrials.gov ID
- NCT07089316
- Acronym / sponsor ID
- 24237859467
- Conditions
- Tibial Meniscus Tears
- Keywords
- Menisci, Tibial, Arthroscopy, Magnetic Resonance Imaging
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 128 participants (actual)
- Lead sponsor
- Karadeniz Technical UniversityUniversity, hospital or other
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 1 Jun 2026 (actual)
- Study completion
- 15 Jun 2026 (actual)
- First posted
- 28 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective observational study aims to investigate whether specific preoperative magnetic resonance imaging (MRI) and radiographic parameters are associated with medial meniscus posterior root tears (MMPRT), and whether these parameters have predictive value for mid-term clinical and radiographic outcomes after arthroscopic repair.
Patients with arthroscopically confirmed MMPRT treated between 2020 and 2024 are evaluated based on their preoperative MRI and standing knee radiographs. Imaging parameters of interest include medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology. Clinical outcomes are assessed using standardized scoring systems. The study aims to identify imaging-based anatomical risk factors to improve diagnosis, patient selection, and prognosis following MMPRT repair.
Detailed description
This retrospective observational study investigates the role of specific preoperative MRI and radiographic parameters in the diagnosis and prognosis of medial meniscus posterior root tears (MMPRT). Conducted at the Department of Orthopaedics and Traumatology, Karadeniz Technical University Farabi Hospital, the study aims to clarify whether morphologic imaging findings-such as medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology-are associated with the presence of MMPRT and influence postoperative outcomes following arthroscopic repair.
All imaging measurements were performed using standardized techniques on MRI and radiographs obtained prior to surgery. Parameters were assessed by two independent orthopedic surgeons on separate occasions to evaluate interobserver reliability. A matched control group of patients without meniscal pathology was formed to strengthen the comparative analysis and support the identification of risk factors.
By analyzing a wide range of anatomic features on imaging, this study seeks to enhance early diagnostic accuracy, improve patient selection for surgical repair, and refine prognostic counseling. The findings are expected to contribute to the development of objective, imaging-based indicators that can guide clinical decision-making and predict mid-term clinical and radiographic outcomes after MMPRT repair.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| MMPRT Patients | – | –Patients with medial meniscus posterior root tears undergoing arthroscopic repair. |
| Control Patients | – | –Patients without meniscus tears, matched by age, BMI, and mechanical axis. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population includes adult patients diagnosed with medial meniscus posterior root tear (MMPRT) who underwent arthroscopic repair at Karadeniz Technical University Farabi Hospital between 2020 and 2024, as well as control patients without meniscus tears who had knee MRI and standing radiographs available in the same period. Controls were matched to the MMPRT group based on age, BMI, and mechanical axis distribution to minimize confounding.
Key inclusion criteria (4 listed)
- Patients aged 18 years or older
- Arthroscopically confirmed medial meniscus posterior root tear (MMPRT) diagnosis
- Availability of preoperative knee MRI and standing long-leg radiographs
- Minimum 24-month clinical and radiographic follow-up
Key exclusion criteria (7 listed)
- Lateral meniscus tear
- Kellgren-Lawrence grade 3 or higher knee osteoarthritis
- Advanced ligament injuries
- History of previous knee surgery, osteotomy, or arthroplasty
- Poor imaging quality
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Medial Tibial Slope
Time frame: Preoperative MRI assessment
Measured in degrees (°) on sagittal MRI. It is the angle between the tangent to the medial tibial plateau and the anatomical axis of the proximal tibia, drawn using a line connecting the anterior and posterior cortices of the plateau.
Medial Meniscus Extrusion
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on coronal MRI. Defined as the distance from the outer margin of the medial meniscus to the edge of the tibial plateau
Tibial Plateau Depth
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on sagittal MRI. It is the perpendicular depth from the deepest point of the medial tibial plateau concavity to a reference line connecting the anterior and posterior cortical rims.
Intercondylar Notch Width
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on axial MRI images. Width of the intercondylar notch at the level of the popliteal groove.
Intercondylar Distance
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on axial MRI. The distance between the outer surfaces of the medial and lateral femoral condyles at the level of the intercondylar notch.
Medial Femoral Condyle Angle
Time frame: Preoperative MRI assessment
Measured in degrees (°) on sagittal MRI. It is the angle between the femoral anatomical axis and the curvature of the medial femoral condyle.
Notch Width Index (ICNW/ICD Ratio)
Time frame: Preoperative MRI assessment
A unitless ratio obtained by dividing the intercondylar notch width by the intercondylar distance on axial MRI at the level of the popliteal groove.
Notch Shape
Time frame: Preoperative MRI assessment
Morphological classification based on axial MRI. The intercondylar notch is categorized into A-type, U-type, or W-type based on its geometric configuration.
Presence of Osteophyte (Spur)
Time frame: Preoperative MRI assessment
Binary variable (Yes/No) indicating the presence of an osteophyte at the intercondylar notch on axial or sagittal MRI.
Medial Femoral Condyle Width (MFCW)
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.
Medial Tibial Plateau Width (MTPW)
Time frame: Preoperative MRI assessment
Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.
MFCW/MTPW Ratio
Time frame: Preoperative MRI assessment
Unitless ratio calculated by dividing medial femoral condyle width (MFCW) by medial tibial plateau width (MTPW) on coronal MRI.
Medial Femoral Condyle Distal Offset Distance
Time frame: Preoperative MRI
Measured in millimeters (mm) on sagittal MRI at the level of the medial femoral condyle midpoint (defined on coronal MRI) as the perpendicular distance from the intercondylar axis to the most distal point of the condyle.
Medial Femoral Condyle Posterior Offset Distance
Time frame: Preoperative MRI
Measured in millimeters (mm) on the same sagittal MRI slice as the distal offset, defined as the distance from the intercondylar axis to the most posterior point of the condyle.
MFC Distal / Posterior Offset Ratio
Time frame: Preoperative MRI
A unitless ratio calculated by dividing the medial femoral condyle distal offset distance by its posterior offset distance on sagittal MRI.
5 secondary outcomes
International Knee Documentation Committee (IKDC) Score
Time frame: Preoperative and minimum 24-month postoperative follow-up
Lysholm Knee Score
Time frame: Preoperative and minimum 24-month postoperative follow-up
Tegner Activity Scale
Time frame: Preoperative and minimum 24-month postoperative follow-up
Kellgren-Lawrence Grade Progression
Time frame: Preoperative and minimum 24-month postoperative radiographs
Medial Joint Space Width (JSW)
Time frame: Preoperative and minimum 24-month postoperative radiographs
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2026.
- Individual participant dataSharing planned: No. No individual participant data (IPD) will be shared for this study. Only aggregate results and statistical analyses will be published to protect patient confidentiality.
Related trials for Tibial Meniscus Tears
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Recruiting
Hemi-tibial Plateau Osteotomy Combined With Arthroscopic Repair for Medial Meniscus Posterior Root Tears in Varus Knees
Knee Osteoarthristis, Meniscus Injury
RecruitingObservational study
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Fevzi Gurkan Aslan, M.D. principal investigator
Karadeniz Technical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Tibial Meniscus Tears, run by Karadeniz Technical University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Medial Tibial Slope (time frame: Preoperative MRI assessment). The study lists 15 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2026.