Pediatric CancerNCT07083674
TeamTalk: Improving Inter-professional Communication During Cancer Treatment
A study testing Multi-level communication intervention in people with Pediatric Cancer, run by Washington University School of Medicine at 1 site in United States.
Trial summary
This study focuses on improving interprofessional communication during cancer treatment, through an individual and hospital system intervention, to improve provider outcomes, patient care, and, ultimately, survival for children with cancer in low-resource settings. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Pediatric Cancer
- What is being tested?
- Multi-level communication intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 8 participants
- Where
- 1 siteUnited States
- Study dates
- 23 Sep 2027to Aug 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Hospitals identified as being in lowest quartile of communication quality, as defined by prior cross-sectional CritCom analysis and measured as the overall CritCom score.
- All Global Alliance hospitals providing childhood cancer care will be eligible to participate.
- Individual participants will be included if they care for hospitalized children with cancer at risk of deterioration.
Who cannot join
- None
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Washington University in St. Louis
St Louis, Missouri, 63110
About this study
Official title: TeamTalk: Strategies to Improve Communication Structure and Quality in Low-resource Childhood Cancer Hospitals
This study focuses on improving interprofessional communication during cancer treatment, through an individual and hospital system intervention, to improve provider outcomes, patient care, and, ultimately, survival for children with cancer in low-resource settings.
- Conditions
- Pediatric Cancer
- Being tested
- Multi-level communication intervention
- Keywords
- Pediatric Cancer, Communication
- Medical subject headings
- Neoplasms, Communication
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multi-level communication interventionBehavioural
The intervention will target multiple levels (provider, unit, hospital) and will respond to identified modifiable communication challenges. Aim 2 intervention mapping will finalize the specific intervention; we anticipate it will involve training and education of staff members and new unit protocols for communication.
| Study group | Role | What they receive |
|---|---|---|
| Intervention Group | Experimental | This study includes an intervention development phase (Aim 2) during which the intervention content and delivery mechanisms will be finalized. We will implement the multilevel intervention developed in Aim 2. We anticipate this will consist of one instance of intervention at each hospital and we will develop a full intervention manual following Aim 2. Details regarding the intervention will be updated prior to participant enrollment in the trial. Receives: Behavioral: Multi-level communication intervention |
| Waitlist Control Group | No intervention | The wait list control is a group that does not receive an intervention during the study period, serving as an untreated comparison during the study, although they later receive the intervention. This intervention will be delivered after the completion of the last data collection instance. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Communication quality - CritCom Measure
Reliable, published measure of communication quality; measured across 6 domains on a Likert scale; self reported by clinical team members; Will assess change in clinician perspective of communication quality within 6 months
Measured: We will evaluate outcomes at three time points; baseline, one month after intervention, and six months after intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2025
- Study start23 Sep 2027 (estimated)
- Primary completionApr 2029 (estimated)
- Study completionAug 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Pediatric CancerStudies of the same condition, open and under way.
- More trials run by Washington University School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Parallel-arm, pilot cluster-randomized wait list-controlled trial to evaluate the intervention compared to control
- Masking
- None (open label)
- Enrolment
- 8 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Washington University School of Medicine
- Sponsor type
- University, hospital or other
- Collaborators
- St. Jude Children's Research Hospital, National Institutes of Health (NIH), National Cancer Institute (NCI)
- Responsible party
- Principal investigator, Sara Malone, Washington University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07083674
- Sponsor's protocol ID
- 202503183
- Other IDs
- 1R01CA287374
- Status last verified
- Dec 2025
- First submitted
- 8 Jul 2025
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
DEVELOPMENT OF A QUANTITATIVE MEASURE (CRITCOM) TO ASSESS THE QUALITY OF INTERDISCIPLINARY COMMUNICATION AROUND PATIENT DETERIORATION IN VARIABLY RESOURCED HOSPITALS
Agulnik A, Graetz DE, Carothers BJ, Rivera J, Blakeney EA, Hayes S, Chaitan VL, Cabassa L, Goss CW, Luke DA, Malone S. Strategies to improve healthcare team communication structure and quality in resource-variable childhood cancer hospitals (TeamTalk): a study protocol. Implement Sci Commun. 2025 Nov 17;6(1):124. doi: 10.1186/s43058-025-00811-z.
PubMed 41250257
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- TeamTalk: Strategies to Improve Communication Structure and Quality in Low-resource Childhood Cancer Hospitals
- ClinicalTrials.gov ID
- NCT07083674
- Acronym / sponsor ID
- 202503183
- Conditions
- Pediatric Cancer
- Keywords
- Pediatric Cancer, Communication
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 8 participants (estimated)
- Lead sponsor
- Washington University School of MedicineUniversity, hospital or other
- Collaborators
- St. Jude Children's Research Hospital, National Institutes of Health (NIH), National Cancer Institute (NCI)
- Study start
- 23 Sep 2027 (estimated)
- Primary completion
- Apr 2029 (estimated)
- Study completion
- Aug 2029 (estimated)
- First posted
- 24 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study focuses on improving interprofessional communication during cancer treatment, through an individual and hospital system intervention, to improve provider outcomes, patient care, and, ultimately, survival for children with cancer in low-resource settings.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Parallel-arm, pilot cluster-randomized wait list-controlled trial to evaluate the intervention compared to control
| Arm | Type | Receives |
|---|---|---|
| Intervention Group | Experimental | Behavioral: Multi-level communication interventionThis study includes an intervention development phase (Aim 2) during which the intervention content and delivery mechanisms will be finalized. We will implement the multilevel intervention developed in Aim 2. We anticipate this will consist of one instance of intervention at each hospital and we will develop a full intervention manual following Aim 2. Details regarding the intervention will be updated prior to participant enrollment in the trial. |
| Waitlist Control Group | No intervention | –The wait list control is a group that does not receive an intervention during the study period, serving as an untreated comparison during the study, although they later receive the intervention. This intervention will be delivered after the completion of the last data collection instance. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Hospitals identified as being in lowest quartile of communication quality, as defined by prior cross-sectional CritCom analysis and measured as the overall CritCom score.
- All Global Alliance hospitals providing childhood cancer care will be eligible to participate.
- Individual participants will be included if they care for hospitalized children with cancer at risk of deterioration.
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multi-level communication interventionThe intervention will target multiple levels (provider, unit, hospital) and will respond to identified modifiable communication challenges. Aim 2 intervention mapping will finalize the specific intervention; we anticipate it will involve training and education of staff members and new unit protocols for communication. | Behavioural | Intervention Group |
Primary outcome
Communication quality - CritCom Measure
Time frame: We will evaluate outcomes at three time points; baseline, one month after intervention, and six months after intervention.
Reliable, published measure of communication quality; measured across 6 domains on a Likert scale; self reported by clinical team members; Will assess change in clinician perspective of communication quality within 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
- BackgroundDEVELOPMENT OF A QUANTITATIVE MEASURE (CRITCOM) TO ASSESS THE QUALITY OF INTERDISCIPLINARY COMMUNICATION AROUND PATIENT DETERIORATION IN VARIABLY RESOURCED HOSPITALS
- Derived from this study: PubMed 41250257Agulnik A, Graetz DE, Carothers BJ, Rivera J, Blakeney EA, Hayes S, Chaitan VL, Cabassa L, Goss CW, Luke DA, Malone S. Strategies to improve healthcare team communication structure and quality in resource-variable childhood cancer hospitals (TeamTalk): a study protocol. Implement Sci Commun. 2025 Nov 17;6(1):124. doi: 10.1186/s43058-025-00811-z.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Multi-level communication intervention in people with Pediatric Cancer, run by Washington University School of Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sara Malone, LCSW, PhD ((502) 797-0240, sara.malone@wustl.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Communication quality - CritCom Measure (time frame: We will evaluate outcomes at three time points; baseline, one month after intervention, and six months after intervention.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07083674, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026.