Nursing StudentNCT07073222
An Escape Room for Nursing Students Taking Pharmacology Classes
A study testing Escape room game in people with Nursing Student and Pharmacology, run by Kahramanmaraş İstiklal University at 1 site in Turkey (Türkiye).
Trial summary
The study was planned as a pre-test-post-test single-group, quasi-experimental design to evaluate the effects of the education provided with the escape room game on the level of autonomic nervous system drug knowledge and perceptions of the game experience in nursing students taking the Pharmacology course. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Nursing Student, Pharmacology
- What is being tested?
- Escape room game
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 6 Jan 2025to 30 Jul 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- First time registration in Pharmacology Course for Nurses,
- Volunteering to participate in the research
Who cannot join
- Having a high school, associate degree or bachelor's degree in a health-related field,
- Having difficulty in understanding and speaking Turkish.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Kahramanmaraş Istiklal University
Kahramanmaraş, Kahramanmaraş, 46100
About this study
Official title: Development and Evaluation of an Escape Room for Nursing Students Taking Pharmacology Course
The study was planned as a pre-test-post-test single-group, quasi-experimental design to evaluate the effects of the education provided with the escape room game on the level of autonomic nervous system drug knowledge and perceptions of the game experience in nursing students taking the Pharmacology course. The sample of the study will consist of students enrolled in the Nursing Pharmacology course at the Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year, who meet the research criteria and agree to participate in the study. The study will be conducted in two stages. In the first stage, the necessary materials for the game development and evaluation process will be prepared and the content validity study of these materials will be conducted. In the second stage, the escape room game will be applied and data will be collected. The data will be collected with the "Descriptive Characteristics Form" and the "Autonomic Nervous System Drug Knowledge Test" (pre-test) before the escape room game, and with the "Autonomic Nervous System Drug Knowledge Test" (post-test) and the "Game Playing Experience Scale" after the game. The analysis of the data will be completed by transferring it to the IBM SPSS Statistics 23 program.
H1a = There is a difference between the mean scores of the autonomic nervous system knowledge test of the students who participated in the escape room game before and after the game.
H1b = There is no difference between the mean scores of the autonomic nervous system knowledge test of the students who participated in the escape room game before and after the game
Read the detailed description
The research was planned in a pretest-posttest one-group, quasi-experimental design design in order to evaluate the effect of the training given with the escape room game on the autonomic nervous system drug knowledge level of the students and their perceptions of the game experience in nursing students taking the Pharmacology course. The population of the study will consist of students enrolled in the Pharmacology Course for Nurses at Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year. In the research, it is planned to reach the universe and no sampling calculation was made. The sample of the research will consist of the students enrolled in the Pharmacology Course for Nurses at Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year, who meet the research criteria and who agree to participate in the research. The research will be conducted in two stages. In the first stage, the materials required for the game development and evaluation process will be prepared and the content validity study of these materials will be carried out. In the second stage, the escape room game will be applied and the data will be collected. The data will be collected before the escape room game with "Descriptive Characteristics Form" and "Autonomic Nervous System Drug Knowledge Test" (pre-test), and after the game with "Autonomic Nervous System Drug Knowledge Test" (post-test) and "Game Playing Experience Scale". Data analysis will be completed by transferring to IBM SPSS Statistics 23 programme. Frequency distribution (number, percentage) for categorical variables and descriptive statistics (mean, standard deviation, minimum, maximum) for numerical variables will be given. Parametric and nonparametric tests will be used according to the normal distribution of the data.
- Conditions
- Nursing Student, Pharmacology
- Being tested
- Escape room game
- Keywords
- escape room, pharmacology, gamification, nursing students
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Escape room gameOther
Escape room games are live action team-based games where players discover clues, solve puzzles and complete tasks in one or more rooms to accomplish a specific goal within a limited time.
| Study group | Role | What they receive |
|---|---|---|
| Escape room playgroup | Experimental | Escape room game is played with escape room game group Receives: Other: Escape room game |
What is being measured
The primary outcome is the main question the study is designed to answer.
Autonomic Nervous System Pharmacology Knowledge Level
Autonomic Nervous System Pharmacology Knowledge Test (ANSPKT) measures the knowledge level of the study participants.
ANSPKT contains 20 five-option multiple-choice questions (a minimum score of 0 and a maximum score of 20) on autonomic nervous system pharmacology, including sympathetic nervous system drugs (5 questions), parasympathetic nervous system drugs (5 questions), the effects of the autonomic nervous system on the body (5 questions), and autonomic nervous system neurotransmitters and receptors (5 questions). This test was evaluated by 40 second-year nursing students. Item analysis was conducted to calculate item difficulty and discrimination. Additionally, the test's KR20 reliability criterion was examined. According to the item analysis, the test was found to be of medium difficulty (0.65) and the KR-20 was found to be 0.76, indicating reliability.
Measured: Before starting the escape game
Secondary outcomes (2)
Autonomic Nervous System Pharmacology Knowledge Level
After the escape room game, the knowledge level of the participants is evaluated with the Autonomic Nervous System Pharmacology Knowledge Test (ANSPKT).
The ANSPKT consists of 20 five-option multiple-choice questions (the lowest possible score is 0, and the highest is 20) related to autonomic nervous system pharmacology, including sympathetic nervous system drugs (5 questions), parasympathetic nervous system drugs (5 questions), the effects of the autonomic nervous system on the body (5 questions), and autonomic nervous system neurotransmitters and receptors (5 questions). This test was evaluated by 40 second-year nursing students. The ANSPKT item analysis was conducted to calculate item difficulty and item discrimination values. Additionally, the test's KR20 reliability measure was examined. According to the item analysis results, the test was found to be of medium difficulty (0.65) and the KR-20 was found to be 0.76, indicating that the test was reliable.
Measured: ANSPKT was applied to the participants one week after the escape room game.
perception of game experience
After the escape room game, participants' game experience perceptions are evaluated with the Gameful Experience Scale (GAMEX).
GAMEX was developed by Eppman et al. (2018) to assess participants' gaming experience. A Turkish validity and reliability study was conducted with nursing students by Çömez İkican et al. (2024). The scale consists of a total of 27 items and 5 subdimensions. The subdimensions are enjoyment, immersion in the game, creative thinking and emotional activation, absence of negative effects, and mastery. A 5-point Likert-type scale is used in the evaluation of the scale, with scores of "Never" (1), "Rarely" (2), "Sometimes" (3), "Frequently" (4), and "Always" (5). Items 18, 21, 22, and 23 of the scale are scored reversely ("Never" (5), "Rarely" (4), "Sometimes" (3), "Frequently" (2), and "Always" (1). In the original and validity-reliability study of the scale, the Cronbach alpha value for the entire scale was found to be 0.89.
Measured: a week after the escape room game
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jul 2025
- Study start6 Jan 2025
- Primary completion10 Feb 2025
- Study completion30 Jul 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Nursing StudentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Kahramanmaraş İstiklal University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nurhan Aktaş, Kahramanmaraş İstiklal University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07073222
- Sponsor's protocol ID
- Istiklal University
- Status last verified
- Jul 2025
- First submitted
- 29 Jun 2025
- Last updated
- 18 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Aktas N, Sazak Y. The use of an escape room-based learning strategy to enhance pharmacology knowledge among nursing students. BMC Nurs. 2025 Dec 31;25(1):106. doi: 10.1186/s12912-025-04270-8.
PubMed 41476208
Study at a glance
From the registry record, last updated by the sponsor on 18 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development and Evaluation of an Escape Room for Nursing Students Taking Pharmacology Course
- ClinicalTrials.gov ID
- NCT07073222
- Acronym / sponsor ID
- Istiklal University
- Conditions
- Nursing Student, Pharmacology
- Keywords
- escape room, pharmacology, gamification, nursing students
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Kahramanmaraş İstiklal UniversityUniversity, hospital or other
- Study start
- 6 Jan 2025 (actual)
- Primary completion
- 10 Feb 2025 (actual)
- Study completion
- 30 Jul 2025 (estimated)
- First posted
- 18 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study was planned as a pre-test-post-test single-group, quasi-experimental design to evaluate the effects of the education provided with the escape room game on the level of autonomic nervous system drug knowledge and perceptions of the game experience in nursing students taking the Pharmacology course. The sample of the study will consist of students enrolled in the Nursing Pharmacology course at the Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year, who meet the research criteria and agree to participate in the study. The study will be conducted in two stages. In the first stage, the necessary materials for the game development and evaluation process will be prepared and the content validity study of these materials will be conducted. In the second stage, the escape room game will be applied and data will be collected. The data will be collected with the "Descriptive Characteristics Form" and the "Autonomic Nervous System Drug Knowledge Test" (pre-test) before the escape room game, and with the "Autonomic Nervous System Drug Knowledge Test" (post-test) and the "Game Playing Experience Scale" after the game. The analysis of the data will be completed by transferring it to the IBM SPSS Statistics 23 program.
H1a = There is a difference between the mean scores of the autonomic nervous system knowledge test of the students who participated in the escape room game before and after the game.
H1b = There is no difference between the mean scores of the autonomic nervous system knowledge test of the students who participated in the escape room game before and after the game
Detailed description
The research was planned in a pretest-posttest one-group, quasi-experimental design design in order to evaluate the effect of the training given with the escape room game on the autonomic nervous system drug knowledge level of the students and their perceptions of the game experience in nursing students taking the Pharmacology course. The population of the study will consist of students enrolled in the Pharmacology Course for Nurses at Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year. In the research, it is planned to reach the universe and no sampling calculation was made. The sample of the research will consist of the students enrolled in the Pharmacology Course for Nurses at Kahramanmaraş İstiklal University, Faculty of Health Sciences, Department of Nursing in the 2024-2025 academic year, who meet the research criteria and who agree to participate in the research. The research will be conducted in two stages. In the first stage, the materials required for the game development and evaluation process will be prepared and the content validity study of these materials will be carried out. In the second stage, the escape room game will be applied and the data will be collected. The data will be collected before the escape room game with "Descriptive Characteristics Form" and "Autonomic Nervous System Drug Knowledge Test" (pre-test), and after the game with "Autonomic Nervous System Drug Knowledge Test" (post-test) and "Game Playing Experience Scale". Data analysis will be completed by transferring to IBM SPSS Statistics 23 programme. Frequency distribution (number, percentage) for categorical variables and descriptive statistics (mean, standard deviation, minimum, maximum) for numerical variables will be given. Parametric and nonparametric tests will be used according to the normal distribution of the data.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Escape room playgroup | Experimental | Other: Escape room gameEscape room game is played with escape room game group |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- First time registration in Pharmacology Course for Nurses,
- Volunteering to participate in the research
Key exclusion criteria (2 listed)
- Having a high school, associate degree or bachelor's degree in a health-related field,
- Having difficulty in understanding and speaking Turkish.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Escape room gameEscape room games are live action team-based games where players discover clues, solve puzzles and complete tasks in one or more rooms to accomplish a specific goal within a limited time. | Other | Escape room playgroup |
Primary outcome
Autonomic Nervous System Pharmacology Knowledge Level
Time frame: Before starting the escape game
Autonomic Nervous System Pharmacology Knowledge Test (ANSPKT) measures the knowledge level of the study participants. ANSPKT contains 20 five-option multiple-choice questions (a minimum score of 0 and a maximum score of 20) on autonomic nervous system pharmacology, including sympathetic nervous system drugs (5 questions), parasympathetic nervous system drugs (5 questions), the effects of the autonomic nervous system on the body (5 questions), and autonomic nervous system neurotransmitters and receptors (5 questions). This test was evaluated by 40 second-year nursing students. Item analysis was conducted to calculate item difficulty and discrimination. Additionally, the test's KR20 reliability criterion was examined. According to the item analysis, the test was found to be of medium difficulty (0.65) and the KR-20 was found to be 0.76, indicating reliability.
2 secondary outcomes
Autonomic Nervous System Pharmacology Knowledge Level
Time frame: ANSPKT was applied to the participants one week after the escape room game.
perception of game experience
Time frame: a week after the escape room game
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jul 2025.
- Derived from this study: PubMed 41476208Aktas N, Sazak Y. The use of an escape room-based learning strategy to enhance pharmacology knowledge among nursing students. BMC Nurs. 2025 Dec 31;25(1):106. doi: 10.1186/s12912-025-04270-8.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Escape room game in people with Nursing Student and Pharmacology, run by Kahramanmaraş İstiklal University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 18 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Autonomic Nervous System Pharmacology Knowledge Level (time frame: Before starting the escape game). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07073222, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jul 2025.