Pain Intensity AssessmentEANCT07041632
Pain Relief in Women Undergoing Oocyte Retrieval (OR) With Electro-acupuncture (EA) or Conscious Sedation (CS) in a Single Assisted Reproduction Centre.
A study testing electro-acupuncture and Conscious sedation in people with Pain Intensity Assessment, run by Singapore General Hospital at 1 site in Singapore.
Trial summary
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS). Read more about this study
- Who is it for?
- Ages 21 to 45 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Pain Intensity Assessment
- What is being tested?
- electro-acupuncture and Conscious sedation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteSingapore
- Study dates
- Jan 2015to 31 Jan 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 45 years
- Women only
- Healthy volunteers accepted
- Adult
Inclusion Criteria: all women undergoing ivf and have given consent -
Exclusion Criteria: women who have infectious skin diseases, women who were unwilling to accept acupunture, history of bleeding disorders.
-
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Can Acupuncture Replace Conscious Sedation in In-Vitro-Fertilization Transvginal Oocyte Retrievals?
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).
Read the detailed description
A total of 60 women were randomized and 29 women were on electro-acupuncture (EA) versus 27 women on conscious sedation (CS) with intravenous medication for transvaginal egg extraction (OR) in IVF. Pain scores were recorded before , during and after egg extraction when the women were on conscious sedation and electro-acupuncture. Side effects were recorded. Physical parameters were recorded. Livebirth outcome were also recorded.
- Conditions
- Pain Intensity Assessment
- Being tested
- electro-acupuncture, Conscious sedation
- Keywords
- acupuncture, oocyte retrieval, sedation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
electro-acupunctureOther
electro-acupuncture for pain relief in egg collection in IVF
Conscious sedationOther
IVf egg collection using conscious sedation as the usual analgesia
| Study group | Role | What they receive |
|---|---|---|
| electro-acupuncture | Active comparator | Electro-acupunture is compared to Conscious sedation during egg collection in IVF Receives: Other: electro-acupuncture |
| Conscious sedation for egg collection | Active comparator | Conscious sedation is the common analgesia used in egg collection in IVF Receives: Other: Conscious sedation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain relief during egg collection
Pain score 1 to 10 during egg collection in IVF compared between using acupuncture and conscious sedation
Measured: from start of egg collection. to 120 minutes after egg collection
Secondary outcomes (1)
Stress, satisfaction measurement and physical parameters between acupuncture and conscious sedation during egg collection in IVF
Stress score and satisfaction outcome scores 0 to 10 for pain relief between acupuncture and conscious sedation during egg collection were recorded. For the stress score, zero is equivalent to no stress and 10 indicates the worst possible stress. For the satisfaction score, zero is equivalent to no satisfaction at all and 10 is the highest satisfaction.
Measured: Up to 120 minutes after egg collection
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jun 2025
- Study startJan 2015
- Primary completion31 Dec 2017
- Study completion31 Jan 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pain Intensity AssessmentStudies of the same condition, open and under way.
- More trials run by Singapore General HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- randomised control
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Singapore General Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Ministry of Health, Singapore
- Responsible party
- Sponsor
- Investigators
- Su Ling Yu, FRCOG, Principal investigator
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07041632
- Sponsor's protocol ID
- Acupuncture in IVF
- Other IDs
- TCMCRG3103002
- Acronym
- EA
- Status last verified
- Jun 2025
- First submitted
- 19 May 2025
- Last updated
- 27 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: This study has completed a few years ago.
Study at a glance
From the registry record, last updated by the sponsor on 27 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Can Acupuncture Replace Conscious Sedation in In-Vitro-Fertilization Transvginal Oocyte Retrievals?
- ClinicalTrials.gov ID
- NCT07041632
- Acronym / sponsor ID
- EA / Acupuncture in IVF
- Conditions
- Pain Intensity Assessment
- Keywords
- acupuncture, oocyte retrieval, sedation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Singapore General HospitalUniversity, hospital or other
- Collaborators
- Ministry of Health, Singapore
- Study start
- Jan 2015 (actual)
- Primary completion
- 31 Dec 2017 (actual)
- Study completion
- 31 Jan 2018 (actual)
- First posted
- 27 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).
Detailed description
A total of 60 women were randomized and 29 women were on electro-acupuncture (EA) versus 27 women on conscious sedation (CS) with intravenous medication for transvaginal egg extraction (OR) in IVF. Pain scores were recorded before , during and after egg extraction when the women were on conscious sedation and electro-acupuncture. Side effects were recorded. Physical parameters were recorded. Livebirth outcome were also recorded.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- randomised control
| Arm | Type | Receives |
|---|---|---|
| electro-acupuncture | Active comparator | Other: electro-acupunctureElectro-acupunture is compared to Conscious sedation during egg collection in IVF |
| Conscious sedation for egg collection | Active comparator | Other: Conscious sedationConscious sedation is the common analgesia used in egg collection in IVF |
Who may qualify
- Ages
- 21 to 45 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| electro-acupunctureelectro-acupuncture for pain relief in egg collection in IVF | Other | electro-acupuncture |
| Conscious sedationIVf egg collection using conscious sedation as the usual analgesia | Other | Conscious sedation for egg collection |
Primary outcome
Pain relief during egg collection
Time frame: from start of egg collection. to 120 minutes after egg collection
Pain score 1 to 10 during egg collection in IVF compared between using acupuncture and conscious sedation
1 secondary outcome
Stress, satisfaction measurement and physical parameters between acupuncture and conscious sedation during egg collection in IVF
Time frame: Up to 120 minutes after egg collection
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Jun 2025.
- Individual participant dataSharing planned: No. This study has completed a few years ago.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Su Ling Yu, FRCOG principal investigator
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing electro-acupuncture and Conscious sedation in people with Pain Intensity Assessment, run by Singapore General Hospital at 1 site in Singapore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Singapore. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain relief during egg collection (time frame: from start of egg collection. to 120 minutes after egg collection). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Jun 2025.