Abdominal Aortic AneurysmNCT07039825
AAA-CTA Cohort Registry
An observational study of Abdominal Aortic Aneurysm and Image, run by RenJi Hospital at 1 site in China.
Trial summary
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and outpatient populations with abdominal aortic aneurysm. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Abdominal Aortic Aneurysm, Image
- What is being tested?
- Computed tomography angiography
- How many people
- 1,000 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2020to 1 May 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with abdominal aortic aneurysm undergoing computed tomography angiography
Who may be able to join
- Patients with abdominal aortic aneurysm who visited the study hospital.
- Patients included should have computed tomography angiography data.
Who cannot join
- 1. Patients who declined participation, cases with incomplete or missing clinical data.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University
Shanghai
Jun Pu, MD,PHD, 86-21-68383477, pujun310@hotmail.com
About this study
Official title: Abdominal Aortic Aneurysm CTA Cohort Study (AAA-CTA Registry)
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and outpatient populations with abdominal aortic aneurysm.
Read the detailed description
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder characterized by irreversible dilation of the abdominal aorta, posing a significant risk of rupture and catastrophic hemorrhage, with mortality rates reaching 65-85% upon rupture. Given the often asymptomatic nature of AAA until rupture, early detection and precise monitoring are critical to prevent fatal outcomes, underscoring the urgent need for reliable diagnostic tools.
Computed tomography angiography (CTA) has emerged as a gold-standard non-invasive imaging technique, offering high-resolution visualization of AAA morphology, including aneurysm diameter, wall thickness, thrombus formation, and spatial relationship to adjacent structures, which are essential for accurate diagnosis, rupture risk stratification, and surgical planning.
This study aims to investigate the precision and clinical utility of CTA in AAA measurement, with the potential to optimize screening protocols, improve intervention timing, and ultimately reduce AAA-related mortality.
By establishing standardized CTA-based assessment criteria, this research may contribute to enhanced diagnostic workflows, better patient risk stratification, and more personalized treatment strategies, thereby addressing a critical gap in vascular disease management.
- Conditions
- Abdominal Aortic Aneurysm, Image
- Being tested
- Computed tomography angiography
- Medical subject headings
- Aortic Aneurysm, Abdominal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Computed tomography angiographyOther
The results of computed tomography angiography on abdominal aortic aneurysm are collected.
What is being measured
The primary outcome is the main question the study is designed to answer.
Maximal abdominal aortic diameter
The images of computed tomography angiography on abdominal aortic aneurysm are collected and the maximal diameter of abdominal artery is measured by medical specialists.
Measured: 1 month
Secondary outcomes (3)
Rupture
The images of computed tomography angiography on abdominal aortic aneurysm are collected and the rupture of AAA is judged by medical specialists.
Measured: 1 month
Mortality
The death of AAA patients is recorded and mortality is calculated.
Measured: 1 month
Other characteristics of AAA morphology
Through CTA images, the existence of ulcer, mural thrombus is judged, and the length of AAA is measured by medical specialists.
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2025
- Study start1 Jan 2020
- Primary completion1 May 2027 (estimated)
- Study completion1 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Abdominal Aortic AneurysmStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- RenJi Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07039825
- Sponsor's protocol ID
- AAA-CTA cohort
- Status last verified
- Jun 2025
- First submitted
- 18 Jun 2025
- Last updated
- 26 Jun 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Abdominal Aortic Aneurysm CTA Cohort Study (AAA-CTA Registry)
- ClinicalTrials.gov ID
- NCT07039825
- Acronym / sponsor ID
- AAA-CTA cohort
- Conditions
- Abdominal Aortic Aneurysm, Image
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- RenJi HospitalUniversity, hospital or other
- Study start
- 1 Jan 2020 (actual)
- Primary completion
- 1 May 2027 (estimated)
- Study completion
- 1 May 2027 (estimated)
- First posted
- 26 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and outpatient populations with abdominal aortic aneurysm.
Detailed description
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder characterized by irreversible dilation of the abdominal aorta, posing a significant risk of rupture and catastrophic hemorrhage, with mortality rates reaching 65-85% upon rupture. Given the often asymptomatic nature of AAA until rupture, early detection and precise monitoring are critical to prevent fatal outcomes, underscoring the urgent need for reliable diagnostic tools.
Computed tomography angiography (CTA) has emerged as a gold-standard non-invasive imaging technique, offering high-resolution visualization of AAA morphology, including aneurysm diameter, wall thickness, thrombus formation, and spatial relationship to adjacent structures, which are essential for accurate diagnosis, rupture risk stratification, and surgical planning.
This study aims to investigate the precision and clinical utility of CTA in AAA measurement, with the potential to optimize screening protocols, improve intervention timing, and ultimately reduce AAA-related mortality.
By establishing standardized CTA-based assessment criteria, this research may contribute to enhanced diagnostic workflows, better patient risk stratification, and more personalized treatment strategies, thereby addressing a critical gap in vascular disease management.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with abdominal aortic aneurysm undergoing computed tomography angiography
Key inclusion criteria (2 listed)
- Patients with abdominal aortic aneurysm who visited the study hospital.
- Patients included should have computed tomography angiography data.
Key exclusion criteria (1 listed)
- 1. Patients who declined participation, cases with incomplete or missing clinical data.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Computed tomography angiographyThe results of computed tomography angiography on abdominal aortic aneurysm are collected. | Other | – |
Primary outcome
Maximal abdominal aortic diameter
Time frame: 1 month
The images of computed tomography angiography on abdominal aortic aneurysm are collected and the maximal diameter of abdominal artery is measured by medical specialists.
3 secondary outcomes
Rupture
Time frame: 1 month
Mortality
Time frame: 1 month
Other characteristics of AAA morphology
Time frame: 1 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Abdominal Aortic Aneurysm and Image, run by RenJi Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jun Pu, MD, PhD (86-21-68383477, pujun310@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maximal abdominal aortic diameter (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2025.