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Plaque PsoriasisDREAMNCT07039110

Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque Psoriasis

An observational study of Plaque Psoriasis, run by AbbVie at 84 sites in 8 countries.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
Search all trials

Trial summary

Psoriasis is a chronic, systemic, inflammatory disease in which skin cells build up and develop thick, red and white scaly patches on the skin. This study will assess the change in quality of life of risankizumab treatment in adult participants with moderate to severe plaque psoriasis real-world clinical practice. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Plaque Psoriasis
How many people
700 participants
Where
84 sitesin 8 countries
Study dates
9 Sep 2025to Mar 2028
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Adult participants with moderate to severe plaque psoriasis who are prescribed risankizumab by their physician.

Who may be able to join

  • Participants with a Confirmed diagnosis of moderate-to-severe plaque psoriasis with or without joint involvement according to the treating physician's clinical judgment, prior to time of enrollment.
  • Treatment with risankizumab is indicated per summary of product characteristics (SmPC) or local label and local prescribing/treatment guidelines.
  • Decision to treat with risankizumab is made prior to and independently of study participation.

Who cannot join

  • History of a sleep disorder diagnosis which the patient is currently being treated for.
  • Current or recent (within the last 30 days) participation in an interventional clinical trial or an observational study.
  • Currently receiving other biologic treatments and/or small molecules including Janus kinase (JAK) inhibitors, tyrosine kinase 2 (TYK2) inhibitors, and phosphodiesterase 4 (PDE4) inhibitors for any reason.

Trial locations and contacts

84 sites in 8 countries. Contact the study team or a site near you to ask about taking part.

Julieta Gonzalez Blanco contact

844-663-3742

julieta.gonzalezblanco@abbvie.com

84 sites in 8 countries

Japan20 sites, 20 recruiting

  • Asahikawa Medical University Hospital /ID# 278981

    Asahikawa-shi, Hokkaido, 078-8510

    Recruiting

  • Juntendo University Hospital /ID# 278495

    Bunkyo-ku, Tokyo, 113-8431

    Recruiting

  • Fukuoka University Hospital /ID# 278600

    Fukuoka, 814-0180

    Recruiting

  • University of the Ryukyus Hospital /ID# 278256

    Ginowan-shi, Okinawa, 901-2725

    Recruiting

  • Tokai University Hospital /ID# 278294

    Isehara, Kanagawa, 259-1193

    Recruiting

  • Kagoshima University Hospital /ID# 278514

    Kagoshima, Kagoshima-ken, 890-8520

    Recruiting

  • Kawasaki Medical School Hospital /ID# 278259

    Kurashiki, Okayama-ken, 701-0192

    Recruiting

  • University Hospital Kyoto Prefectural University of Medicine /ID# 278962

    Kyoto, Kyoto, 602-8566

    Recruiting

  • Gunma University Hospital /ID# 278497

    Maebashi, Gunma, 371-8511

    Recruiting

  • Nippon Life Saiseikai Public Interest Foundation Nippon Life Hospital /ID# 278434

    Osaka, 550-0006

    Recruiting

  • Kindai University Hospital /ID# 278258

    Sakai-shi, Osaka, 590-0197

    Recruiting

  • Hokkaido University Hospital /ID# 278260

    Sapporo, Hokkaido, 060-8648

    Recruiting

  • Hosui General Medical Clinic /ID# 279520

    Sapporo, Hokkaido, 0640807

    Recruiting

  • Jichi Medical University Hospital /ID# 280236

    Shimotsuke-shi, Tochigi, 329-0498

    Recruiting

  • Seibo Hospital /ID# 279522

    Shinjuku-ku, Tokyo, 161-8521

    Recruiting

  • The University of Osaka Hospital /ID# 278436

    Suita-shi, Osaka, 565-0871

    Recruiting

  • Tokyo Yamate Medical Center /ID# 278960

    Tokyo, 169-0073

    Recruiting

  • Teikyo University Hospital /ID# 278228

    Tokyo, 173-8605

    Recruiting

  • Nihon University Itabashi Hospital /ID# 279916

    Tokyo, 173-8610

    Recruiting

  • Yokohama City University Hospital /ID# 278257

    Yokohama, Kanagawa, 236-0004

    Recruiting

Other trials in Japan

Canada18 sites, 17 recruiting

  • Cca Medical Research /ID# 276944

    Ajax, Ontario, L1S 7K8

    Recruiting

  • Quinte dermatology /ID# 277497

    Belleville, Ontario, K8N 2S9

    Recruiting

  • Dermatology Research Institute - Blackfoot Trail /ID# 276722

    Calgary, Alberta, T2J 7E1

    Recruiting

  • Rejuvenation Dermatology - Edmonton Downtown /ID# 276688

    Edmonton, Alberta, T5J 3S9

    Recruiting

  • Dermatrials Research /ID# 276714

    Hamilton, Ontario, L8N 1Y2

    Completed

  • Lovegrove Dermatology /ID# 276797

    London, Ontario, N6A 5R9

    Recruiting

  • Lynderm Research Inc /ID# 276755

    Markham, Ontario, L3P 1X2

    Recruiting

  • Rejuvenation Dermatology Clinic Oakville /ID# 277492

    Oakville, Ontario, L6H 6P8

    Recruiting

  • JRB Research inc. /ID# 277730

    Ottawa, Ontario, K1K 4L2

    Recruiting

  • Factor Dermatology /ID# 278610

    Ottawa, Ontario, K2A 2M3

    Recruiting

  • SKiN Centre for Dermatology /ID# 277594

    Peterborough, Ontario, K9J 5K2

    Recruiting

  • Dre Angelique Gagne-Henley M.D. inc. /ID# 276687

    Saint-Jérôme, Quebec, J7Z 7E2

    Recruiting

  • Eternal Springtime Dermatology /ID# 278598

    Thunder Bay, Ontario, P7C 4Y7

    Recruiting

  • North York Research /ID# 276835

    Toronto, Ontario, M2N 3A6

    Recruiting

  • Avenue Research Group /ID# 276846

    Toronto, Ontario, M5N 1A8

    Recruiting

  • Centre for Medical and Surgical Dermatology /ID# 278775

    Whitby, Ontario, L1N 8M7

    Recruiting

  • Winnipeg Clinic /ID# 276751

    Winnipeg, Manitoba, R3C 1T6

    Recruiting

  • Wiseman Dermatology Research /ID# 276847

    Winnipeg, Manitoba, R3M 3Z4

    Recruiting

Other trials in Canada

Germany12 sites, 11 recruiting

  • Klinikum Dortmund Klinikzentrum Mitte /ID# 284856

    Dortmund, North Rhine-Westphalia, 44137

    Recruiting

  • Dr. med. Moritz Huber und Dr. med. Martin Heister /ID# 277627

    Friedrichshafen, Baden-Wurttemberg, 88046

    Recruiting

  • Universitaetsklinikum Hamburg-Eppendorf /ID# 277164

    Hamburg, 20246

    Recruiting

  • Cutaneum /ID# 277294

    Hamburg, 20249

    Recruiting

  • Private Practice - Dr. Mario Pawlak /ID# 277465

    Heilbad Heiligenstadt, 37308

    Recruiting

  • Dermakulm /Id# 277864

    Kulmbach, Bavaria, 95326

    Recruiting

  • Hautarztpraxis Dr. Med. Ulrike Wiemers / Dr. Med. Franca Wiemers /ID# 277821

    Leipzig, 04317

    Completed

  • Universitaetsmedizin Mainz /ID# 278229

    Mainz, Rhineland-Palatinate, 55131

    Recruiting

  • Dermatologie Moelln Praxis Dr. Bodo Segert /ID# 277628

    Mölln, Schleswig-Holstein, 23879

    Recruiting

  • Dermazent /Id# 280327

    Munich, Bavaria, 80331

    Recruiting

  • Hautaerzte am Nauener Tor /ID# 284579

    Potsdam, Brandenburg, 14469

    Recruiting

  • Hautarztpraxis Schwelm /ID# 277464

    Schwelm, 58332

    Recruiting

Other trials in Germany

Greece9 sites, 9 recruiting

  • General Hospital Andreas Syggros /ID# 276826

    Athens, Attica, 16121

    Recruiting

  • General Hospital Andreas Syggros /ID# 279246

    Athens, Attica, 16121

    Recruiting

  • University General Hospital Attikon /ID# 278389

    Chaïdári, Attica, 12462

    Recruiting

  • The University Hospital of Larissa /ID# 276576

    Larissa, Thessaly, 41110

    Recruiting

  • Tzaneio Prefecture General Hospital of Piraeus /ID# 276532

    Piraeus, Attica, 18536

    Recruiting

  • Hospital of Skin and Venereal Diseases- Thessaloniki /ID# 276488

    Thessaloniki, 54643

    Recruiting

  • Hospital of Skin and Venereal Diseases- Thessaloniki /ID# 276489

    Thessaloniki, 54643

    Recruiting

  • Papageorgiou General Hospital /ID# 276487

    Thessaloniki, 56429

    Recruiting

  • Asklipieio General Hospital of Voula /ID# 278235

    Voula, Attica, 16673

    Recruiting

Other trials in Greece

France7 sites, 7 recruiting

  • Dr. Rima Mohty /ID# 279951

    Beauvais, Oise, 60000

    Recruiting

  • Hopital Ambroise-Pare /ID# 280402

    Boulogne-Billancourt, 92104

    Recruiting

  • Chu de Dijon /ID# 279900

    Dijon, Bourgogne-Franche-Comté, 21000

    Recruiting

  • Centre Hospitalier Du Mans /ID# 279899

    Le Mans, Sarthe, 72037

    Recruiting

  • Centre Hospitalier de Niort Georges Renon /ID# 279604

    Niort, Deux-Sevres, 79021

    Recruiting

  • Hopitaux Drome Nord - Romans /ID# 278109

    Romans-sur-Isère, Drome, 26102

    Recruiting

  • Hopital d'Instruction des Armees Sainte-Anne /ID# 278106

    Toulon, Var, 83800

    Recruiting

Other trials in France

Spain7 sites, 7 recruiting

  • Hospital General Universitario Santa Maria Del Rosell /ID# 277894

    Cartagena, Murcia, 30203

    Recruiting

  • Hospital Clinico Universitario Virgen de la Arrixaca /ID# 283338

    El Palmar, Murcia, 30120

    Recruiting

  • Hospital Universitario de Leon /ID# 277895

    León, Leon, 24080

    Recruiting

  • Hospital Regional Universitario de Malaga /ID# 277220

    Málaga, Andalusia, 29010

    Recruiting

  • Hospital General Universitario Morales Meseguer /ID# 283339

    Murcia, 30008

    Recruiting

  • Complejo Hospitalario Universitario de Pontevedra /ID# 278085

    Pontevedra, 36071

    Recruiting

  • Hospital Universitario De Toledo /ID# 277896

    Toledo, 45007

    Recruiting

Other trials in Spain

Czechia6 sites, 6 recruiting

  • Fakultni Nemocnice U Sv. Anny V Brne /ID# 275799

    Brno, Brno-mesto, 656 91

    Recruiting

  • Nemocnice Ceske Budejovice /ID# 275541

    České Budějovice, 370 01

    Recruiting

  • Dermafit Centrum /ID# 275897

    Pilsen, Plzeň Region, 323 00

    Site Coordinator, +420 377 534 145

    Recruiting

  • Fakultni nemocnice Bulovka /ID# 275540

    Prague, Central Bohemia, 180 81

    Recruiting

  • Dermamedest /ID# 275898

    Prague, Praha 2, 120 00

    Recruiting

  • Fakultni nemocnice Kralovske Vinohrady /ID# 275800

    Prague, 100 34

    Recruiting

Other trials in Czechia

Italy5 sites, 5 recruiting

  • Ospedale San Martino /ID# 278984

    Genova, 16132

    Recruiting

  • ASL 1 Abruzzo - Ospedale regionale San Salvatore /ID# 277341

    L’Aquila, L Aquila, 67100

    Recruiting

  • IRCCS Ospedale San Raffaele /ID# 277342

    Milan, Milano, 20132

    Recruiting

  • Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 277713

    Naples, Napoli, 80138

    Recruiting

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 278080

    Rome, Roma, 00168

    Recruiting

Other trials in Italy

About this study

Official title: The Real-World Impact of Risankizumab on the Quality of Life and Cumulative Life Course Impairment (CLCI) in Patients With Moderate-to-Severe Plaque Psoriasis (DREAM)

Psoriasis is a chronic, systemic, inflammatory disease in which skin cells build up and develop thick, red and white scaly patches on the skin. This study will assess the change in quality of life of risankizumab treatment in adult participants with moderate to severe plaque psoriasis real-world clinical practice.

Risankizumab is an approved drug for treating participants with Psoriasis. Approximately 700 participants who are prescribed risankizumab by their physician in accordance with local label will be enrolled in approximately 70 sites worldwide.

Read more

Participants will receive risankizumab as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 2.5 years.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Keywords
Plaque Psoriasis, Moderate to Severe Plaque Psoriasis, Risankizumab

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07039110
Study groupRoleWhat they receive
RisankizumabParticipants will receive risankizumab as prescribed by their physician according to local label.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Proportion of participants achieving a Dermatology Life Quality Index (DLQI) score of 0 or 1

    DLQI (Dermatology Life Quality Index) assesses symptoms and impacts of dermatologic diseases on quality of life. DLQI scores range from 0 (no at all) to 1 (a little).

    Measured: At 12 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted26 Jun 2025
  2. Study start9 Sep 2025
  3. Primary completionMar 2028 (estimated)
  4. Study completionMar 2028 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
700 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07039110
Sponsor's protocol ID
P25-187
Acronym
DREAM
Status last verified
Sep 2026
First submitted
18 Jun 2025
Last updated
1 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

An observational study of Plaque Psoriasis, run by AbbVie at 84 sites in 8 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 84 sites in Japan, Canada, Germany, Greece, France and 3 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Julieta Gonzalez Blanco (844-663-3742, julieta.gonzalezblanco@abbvie.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Proportion of participants achieving a Dermatology Life Quality Index (DLQI) score of 0 or 1 (time frame: At 12 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07039110.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.

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