Dental CariesNCT07031856
Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM
A study testing 3D printer partial crown and Treatment as usual in people with Dental Caries and Dental Restoration, Permanent, run by Cukurova University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths. The main question it aims to answer is: Is there a difference between CAD-CAM and 3D restorations according to FDI criteria? Researchers will compare participants to see… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- What is being tested?
- 3D printer partial crown and Treatment as usual
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 12 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jul 2025to Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
None listed.
Who cannot join
- Patients with systemic conditions that may affect the study process (e.g. diabetes, autoimmune diseases).
- Patients with excessive bruxism or parafunctional habits.
- Pregnant or lactating women.
- Patients with gum disease or severe bone loss.
- Patients with a history of allergic reactions.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Çukurova Üniversitesi Diş Hekimliği Fakültesi
Adana, Sarıçam, 01250
Yaren Coşğun, Dr., +90 544 745 8633, yarenncoskun@gmail.com
About this study
Official title: Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths. The main question it aims to answer is: Is there a difference between CAD-CAM and 3D restorations according to FDI criteria? Researchers will compare participants to see if there is a difference between the two restorations according to FDI criteria. In this split-mouth study, participants will be randomized to receive a CAD-CAM partial restoration on one tooth and a 3D partial restoration on the other tooth.
- Conditions
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- Being tested
- 3D printer partial crown, Treatment as usual
- Medical subject headings
- Dental Caries, Tooth Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
3D printer partial crownOther
Comprasion of partial restorations made with 3D printer
Treatment as usualOther
Cad-cam printer partial crown
| Study group | Role | What they receive |
|---|---|---|
| 3D printer partial crown | Experimental | Participant with restoration produced with 3D printer Receives: Other: 3D printer partial crown |
| Cad-Cam partial crown | Other | Participant with restoration produced with Cad-Cam Receives: Other: Treatment as usual |
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinical performance of dental restorations evaluated using FDI World Dental Federation criteria
Esthetic Properties Color match (shade stability) Surface staining Translucency/opacity Anatomical form preservation Functional Properties Fracture and retention Marginal adaptation (gap formation) Wear resistance Occlusal contact stability Biological Properties (Newly added) Postoperative hypersensitivity (pulp reactions) Secondary caries development Periodontal response (gingival inflammation, bleeding on probing) Tooth integrity (adjacent tooth structure)
Measured: Baseline, six months, 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jun 2025
- Study start1 Jul 2025
- Primary completion1 Nov 2025
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental CariesStudies of the same condition, open and under way.
- More trials run by Cukurova UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 12 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cukurova University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yaren Cosgun, Cukurova University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07031856
- Sponsor's protocol ID
- T.C. Ç.Ü BAP
- Status last verified
- Mar 2026
- First submitted
- 20 May 2025
- Last updated
- 2 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 2 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07031856
- Acronym / sponsor ID
- T.C. Ç.Ü BAP
- Conditions
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 12 participants (estimated)
- Lead sponsor
- Cukurova UniversityUniversity, hospital or other
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 1 Nov 2025 (actual)
- Study completion
- Nov 2026 (estimated)
- First posted
- 22 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths. The main question it aims to answer is: Is there a difference between CAD-CAM and 3D restorations according to FDI criteria? Researchers will compare participants to see if there is a difference between the two restorations according to FDI criteria. In this split-mouth study, participants will be randomized to receive a CAD-CAM partial restoration on one tooth and a 3D partial restoration on the other tooth.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| 3D printer partial crown | Experimental | Other: 3D printer partial crownParticipant with restoration produced with 3D printer |
| Cad-Cam partial crown | Other | Other: Treatment as usualParticipant with restoration produced with Cad-Cam |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (0 listed)
Key exclusion criteria (5 listed)
- Patients with systemic conditions that may affect the study process (e.g. diabetes, autoimmune diseases).
- Patients with excessive bruxism or parafunctional habits.
- Pregnant or lactating women.
- Patients with gum disease or severe bone loss.
- Patients with a history of allergic reactions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 3D printer partial crownComprasion of partial restorations made with 3D printer | Other | 3D printer partial crown |
| Treatment as usualCad-cam printer partial crown | Other | Cad-Cam partial crown |
Primary outcome
Clinical performance of dental restorations evaluated using FDI World Dental Federation criteria
Time frame: Baseline, six months, 12 months
Esthetic Properties Color match (shade stability) Surface staining Translucency/opacity Anatomical form preservation Functional Properties Fracture and retention Marginal adaptation (gap formation) Wear resistance Occlusal contact stability Biological Properties (Newly added) Postoperative hypersensitivity (pulp reactions) Secondary caries development Periodontal response (gingival inflammation, bleeding on probing) Tooth integrity (adjacent tooth structure)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Apr 2026.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 3D printer partial crown and Treatment as usual in people with Dental Caries and Dental Restoration, Permanent, run by Cukurova University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Research Assistant (+90 0544 745 8633, yarenncoskun@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinical performance of dental restorations evaluated using FDI World Dental Federation criteria (time frame: Baseline, six months, 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Apr 2026.