Bonding of Veneers After Different TreatmentNCT07027709
Clinical Performance of Hybrid Ceramic Laminate Veneers
A study testing BeautiBond Xtreme pretreatment with BeautiLink SA cementation and HC Primer pretreatment with BeautiLink SA cementation in people with Bonding of Veneers After Different Treatment, run by Cairo University at 1 site in Egypt.
Trial summary
This randomized controlled trial evaluates the clinical performance of laminate veneers fabricated from HC hard blocks pretreated with BeautiBond Xtreme versus HC Primer, using BeautiLink SA cement. The study focuses on marginal adaptation, retention, discoloration, and recurrent caries over 18 months. Read more about this study
- Who is it for?
- Ages 21 years and older
- Conditions the study is for
- Bonding of Veneers After Different Treatment
- What is being tested?
- BeautiBond Xtreme pretreatment with BeautiLink SA cementation and HC Primer pretreatment with BeautiLink SA cementation
- Type of treatment
- Medical device, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2025to 1 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Inclusion Criteria:dult patients ≥ 21 years requiring laminate veneers in the esthetic zone, vital or endodontically treated teeth, sufficient enamel, willing and able to consent and comply.
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Exclusion Criteria: Periodontal disease, bruxism, poor hygiene, pregnancy, systemic illness, allergies, insufficient enamel, ongoing trials, orthodontic treatment.
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Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Faculty of Dentistry Cairo University
Cairo
Reham said el basty, professor, 00201207169671, reham.elbasty@dentistry.cu.edu.eg
About this study
Official title: Clinical Performance of Hybrid Ceramic Laminate Veneers With Two Pretreatment Protocols: A Randomized Clinical Trial
This randomized controlled trial evaluates the clinical performance of laminate veneers fabricated from HC hard blocks pretreated with BeautiBond Xtreme versus HC Primer, using BeautiLink SA cement. The study focuses on marginal adaptation, retention, discoloration, and recurrent caries over 18 months.
Read the detailed description
This clinical trial compares two bonding protocols for hybrid ceramic laminate veneers. The veneers are fabricated from HC hard blocks and bonded using BeautiLink SA resin cement. One group receives BeautiBond Xtreme pretreatment, while the other receives HC Primer. The study assesses marginal adaptation, retention, recurrent caries, and discoloration over 18 months to determine the superior clinical bonding protocol for these restorations.
- Being tested
- BeautiBond Xtreme pretreatment with BeautiLink SA cementation, HC Primer pretreatment with BeautiLink SA cementation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
BeautiBond Xtreme pretreatment with BeautiLink SA cementationDevice
Laminate veneers fabricated from HC hard blocks were pretreated on the internal surface with BeautiBond Xtreme, then bonded to tooth structure using BeautiLink SA self-adhesive resin cement. The tooth surfaces were also treated with BeautiBond Xtreme. Veneers were digitally designed and milled, then cemented following a standardized clinical protocol.
HC Primer pretreatment with BeautiLink SA cementationProcedure or surgery
Laminate veneers fabricated from HC hard blocks were pretreated on the internal surface with HC Primer, then bonded to tooth structure using BeautiLink SA self-adhesive resin cement. The tooth surfaces were treated with BeautiBond Xtreme. Veneers were digitally designed and milled, then cemented following the same clinical protocol used in the experimental grou
| Study group | Role | What they receive |
|---|---|---|
| BeautiBond Xtreme Pretreatment Group | Experimental | atients in this group will receive laminate veneers fabricated from HC hard blocks. The inner surface of the veneers will be pretreated with BeautiBond Xtreme, and the veneers will be bonded using BeautiLink SA self-adhesive resin cement. This group is used to assess the clinical performance of BeautiBond Xtreme pretreatment over an 18-month follow-up. Receives: Device: BeautiBond Xtreme pretreatment with BeautiLink SA cementation |
| HC Primer Pretreatment Group | Active comparator | atients in this group will receive laminate veneers fabricated from HC hard blocks. The inner surface of the veneers will be pretreated with HC Primer, and the veneers will be bonded using BeautiLink SA self-adhesive resin cement. This group serves as a comparator to evaluate differences in clinical outcomes relative to the BeautiBond Xtreme group. Receives: Procedure: HC Primer pretreatment with BeautiLink SA cementation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Primary Outcome: Marginal Adaptation
(Modified USPHS)
Measured: Measured at 6, 12, 18 months.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jun 2025
- Study start1 Jun 2025
- Primary completion1 Dec 2026 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Bonding of Veneers After Different TreatmentStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 28 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Omnia Mohammed Wafik, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07027709
- Sponsor's protocol ID
- CU-FP-HCLV-001
- Status last verified
- Jun 2025
- First submitted
- 11 Jun 2025
- Last updated
- 18 Jun 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: this is a university-sponsored clinical study with a small sample size and limited scope. No plan to share individual participant data (IPD) has been established due to privacy considerations and the nature of the trial. However, summary-level results may be published in peer-reviewed journals and conferences.
Publications
Çötert İ, Çötert HS. Survival of partial laminate veneers and categorical covariates affecting the survival: a systematic review. Open Dent J. 2023;17(1) Ho CCK. Appraisal and cementation of porcelain laminate veneers. In: Banerji S, Mehta SB, Ho CCK, editors. Practical procedures in aesthetic dentistry. West Sussex: John Wiley & Sons; 2017. Bajaj M, Jha P, Nikhil V. Shade selection in esthetic dentistry. IP Indian J Conserv Endod. 2023;8(2):79-85. http://doi. org/10.18231/j.ijce.2023.015. De Munck, J., Van Landuyt, K., Peumans, M., Poitevin, A., Lambrechts, P., Braem, M., & Van Meerbeek, B. (2012). A critical review of the durability of adhesion to tooth tissue: methods and results. Journal of Dental Research, 91(4), 351-381. Frankenberger, R., Hartmann, V. E., Krech, M., Krämer, N., Reich, S., Braun, A., & Roggendorf, M. (2015). Adhesive luting of new CAD/CAM materials. International Journal of Computerized Dentistry, 18(1), 9-20. Morimoto, S., Rebello de Sampaio, F. B., Braga, M. M., Sesma, N., & Özcan, M. (2016). Survival rate of resin and ceramic inlays, onlays, and overlays: a systematic review and meta-analysis. Journal of Dental Research, 95(9), 985-994. Lawson, N. C., Bansal, R., & Burgess, J. O. (2016). Wear, strength, modulus and hardness of CAD/CAM restorative materials. Dental Materials, 32(11), e275-e283. El Zohairy, A.A.; De Gee, A.J.; Mohsen, M.M.; Feilzer, A.J. Microtensile bond strength testing of luting cements to prefabricated CAD/CAM ceramic and composite blocks. Dent. Mater. 2003, 19, 575-583.Lührs, A. K., De Munck, J., Geurtsen, W., & Van Meerbeek, B. (2014). Composite cements benefit from light-curing. Dental Materials, 30(3), 292-301. Frankenberger, R.; Lohbauer, U.; Taschner, M.; Petschelt, A.; Nikolaenko, S.A. Adhesive luting revisited: influence of adhesive, temporary cement, cavity cleaning, and curing mode on internal dentin bond strength. J. Adhes. Dent. 2007, 9, 269-273. Dos Santos, V.H.; Griza, S.; de Morae
Study at a glance
From the registry record, last updated by the sponsor on 18 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Performance of Hybrid Ceramic Laminate Veneers With Two Pretreatment Protocols: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07027709
- Acronym / sponsor ID
- CU-FP-HCLV-001
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 28 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 18 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial evaluates the clinical performance of laminate veneers fabricated from HC hard blocks pretreated with BeautiBond Xtreme versus HC Primer, using BeautiLink SA cement. The study focuses on marginal adaptation, retention, discoloration, and recurrent caries over 18 months.
Detailed description
This clinical trial compares two bonding protocols for hybrid ceramic laminate veneers. The veneers are fabricated from HC hard blocks and bonded using BeautiLink SA resin cement. One group receives BeautiBond Xtreme pretreatment, while the other receives HC Primer. The study assesses marginal adaptation, retention, recurrent caries, and discoloration over 18 months to determine the superior clinical bonding protocol for these restorations.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| BeautiBond Xtreme Pretreatment Group | Experimental | Device: BeautiBond Xtreme pretreatment with BeautiLink SA cementationatients in this group will receive laminate veneers fabricated from HC hard blocks. The inner surface of the veneers will be pretreated with BeautiBond Xtreme, and the veneers will be bonded using BeautiLink SA self-adhesive resin cement. This group is used to assess the clinical performance of BeautiBond Xtreme pretreatment over an 18-month follow-up. |
| HC Primer Pretreatment Group | Active comparator | Procedure: HC Primer pretreatment with BeautiLink SA cementationatients in this group will receive laminate veneers fabricated from HC hard blocks. The inner surface of the veneers will be pretreated with HC Primer, and the veneers will be bonded using BeautiLink SA self-adhesive resin cement. This group serves as a comparator to evaluate differences in clinical outcomes relative to the BeautiBond Xtreme group. |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| BeautiBond Xtreme pretreatment with BeautiLink SA cementationLaminate veneers fabricated from HC hard blocks were pretreated on the internal surface with BeautiBond Xtreme, then bonded to tooth structure using BeautiLink SA self-adhesive resin cement. The tooth surfaces were also treated with BeautiBond Xtreme. Veneers were digitally designed and milled, then cemented following a standardized clinical protocol. | Device | BeautiBond Xtreme Pretreatment Group |
| HC Primer pretreatment with BeautiLink SA cementationLaminate veneers fabricated from HC hard blocks were pretreated on the internal surface with HC Primer, then bonded to tooth structure using BeautiLink SA self-adhesive resin cement. The tooth surfaces were treated with BeautiBond Xtreme. Veneers were digitally designed and milled, then cemented following the same clinical protocol used in the experimental grou | Procedure or surgery | HC Primer Pretreatment Group |
Primary outcome
Primary Outcome: Marginal Adaptation
Time frame: Measured at 6, 12, 18 months.
(Modified USPHS)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jun 2025.
- Results publicationÇötert İ, Çötert HS. Survival of partial laminate veneers and categorical covariates affecting the survival: a systematic review. Open Dent J. 2023;17(1) Ho CCK. Appraisal and cementation of porcelain laminate veneers. In: Banerji S, Mehta SB, Ho CCK, editors. Practical procedures in aesthetic dentistry. West Sussex: John Wiley & Sons; 2017. Bajaj M, Jha P, Nikhil V. Shade selection in esthetic dentistry. IP Indian J Conserv Endod. 2023;8(2):79-85. http://doi. org/10.18231/j.ijce.2023.015. De Munck, J., Van Landuyt, K., Peumans, M., Poitevin, A., Lambrechts, P., Braem, M., & Van Meerbeek, B. (2012). A critical review of the durability of adhesion to tooth tissue: methods and results. Journal of Dental Research, 91(4), 351-381. Frankenberger, R., Hartmann, V. E., Krech, M., Krämer, N., Reich, S., Braun, A., & Roggendorf, M. (2015). Adhesive luting of new CAD/CAM materials. International Journal of Computerized Dentistry, 18(1), 9-20. Morimoto, S., Rebello de Sampaio, F. B., Braga, M. M., Sesma, N., & Özcan, M. (2016). Survival rate of resin and ceramic inlays, onlays, and overlays: a systematic review and meta-analysis. Journal of Dental Research, 95(9), 985-994. Lawson, N. C., Bansal, R., & Burgess, J. O. (2016). Wear, strength, modulus and hardness of CAD/CAM restorative materials. Dental Materials, 32(11), e275-e283. El Zohairy, A.A.; De Gee, A.J.; Mohsen, M.M.; Feilzer, A.J. Microtensile bond strength testing of luting cements to prefabricated CAD/CAM ceramic and composite blocks. Dent. Mater. 2003, 19, 575-583.Lührs, A. K., De Munck, J., Geurtsen, W., & Van Meerbeek, B. (2014). Composite cements benefit from light-curing. Dental Materials, 30(3), 292-301. Frankenberger, R.; Lohbauer, U.; Taschner, M.; Petschelt, A.; Nikolaenko, S.A. Adhesive luting revisited: influence of adhesive, temporary cement, cavity cleaning, and curing mode on internal dentin bond strength. J. Adhes. Dent. 2007, 9, 269-273. Dos Santos, V.H.; Griza, S.; de Morae
- Individual participant dataSharing planned: Undecided. this is a university-sponsored clinical study with a small sample size and limited scope. No plan to share individual participant data (IPD) has been established due to privacy considerations and the nature of the trial. However, summary-level results may be published in peer-reviewed journals and conferences.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing BeautiBond Xtreme pretreatment with BeautiLink SA cementation and HC Primer pretreatment with BeautiLink SA cementation in people with Bonding of Veneers After Different Treatment, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 18 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact omnia Mohammed Wafik, lecturer (00201006595375, omniawafik@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Primary Outcome: Marginal Adaptation (time frame: Measured at 6, 12, 18 months.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07027709, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jun 2025.