HealthyNCT07020234

National Survey to Understand Ethical, Legal and Social Issues in Communicating to the Public About Epigenetics

A study testing Epigenetics Video and Nanotechnology Video in people with Healthy, run by Washington University School of Medicine at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic modification." This study will develop and test strategies for communicating about epigenetics that… Read more about this study

Who is it for?: Ages 18 years and olderHealthy volunteers can take part
Conditions the study is for: Healthy
What is being tested?: Epigenetics Video and Nanotechnology Video
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 2,040 participants
Where: 1 siteUnited States
Study dates: 12 Jun 2025to 18 Jul 2025
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

English language speaker,
Identify as one of five racial/ethnic groups:
Non-Hispanic White
Non-Hispanic Black,
Non-Hispanic Asian
Non-Hispanic Indigenous (i.e., Alaska Native/Native Hawaiians/American Indian/Other Pacific Islander)
Hispanic (all races)

Who cannot join

Self-identify as a genetics expert

Trial locations and contacts

1 site in 1 country.

United States1 site

Washington University School of Medicine
St Louis, Missouri, 63110

Other trials in United States

About this study

Official title: Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research: National Survey

Conditions: Healthy
Being tested: Epigenetics Video, Nanotechnology Video
Keywords: Epigenomics, Epigenetics, Genetics, Behavioral, Bioethics
Medical subject headings: Behavior

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Epigenetics VideoBehavioural
Educational video about health and epigenetics.
Nanotechnology VideoBehavioural
Educational video about nanotechnology

Study groups in NCT07020234
Study group	Role	What they receive
Epigenetics Video	Experimental	Participants will watch a brief (<5 minute) video about the concept of Epigenetics Receives: Behavioral: Epigenetics Video
Nanotechnology Video	Active comparator	Participants will watch a brief (<5 minute) video about nanotechnology Receives: Behavioral: Nanotechnology Video

What is being measured

The primary outcome is the main question the study is designed to answer.

Knowledge & Understanding of Epigenetics Information
We will measure this outcome using a sum score of correct answers for 8 individual items. Scale ranges from 0 points to 8 points with higher scores indicating higher epigenetics knowledge.
Measured: After intervention video

Secondary outcomes (2)

Acceptability of Epigenetics Information
We will measure this outcome using 3 different constructs including perceived benefits of epigenetic research (items 1-7, ranging from 1 to 5 with higher scores indicating higher perceived benefits), perceived drawbacks of epigenetic research (items 8-10, ranging from 1 to 5 with higher scores indicating higher perceived drawbacks), and acceptance of using epigenetic research in medical support (items 11-13, ranging from 1 to 5 with higher scores indicating higher acceptance of using epigenetic research in medical support). Each item was analyzed separately.
Measured: After intervention video
Perceptions of Epigenetic Information
We will measure this outcome using an 6 item scale. Scores range from 1 to 5, with higher scores indicating greater perceptions of epigenetic information.
Measured: After intervention video

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

12 Jun 202518 Jul 2025

First posted13 Jun 2025
Study start12 Jun 2025
Primary completion18 Jul 2025
Study completion18 Jul 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Other trials for HealthyStudies of the same condition, open and under way.
More trials run by Washington University School of MedicineThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Other
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 2,040 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07020234
Sponsor's protocol ID: 202503082
Other IDs: R01ES033743
Status last verified: Oct 2026
First submitted: 5 Jun 2025
Last updated: 14 Oct 2026
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: Yes

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Healthy trials

Study at a glance

From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research: National Survey
ClinicalTrials.gov ID: NCT07020234
Acronym / sponsor ID: 202503082
Conditions: Healthy
Keywords: Epigenomics, Epigenetics, Genetics, Behavioral, Bioethics
Study type: Interventional
Recruitment status: Completed
Enrolment: 2,040 participants (actual)
Lead sponsor: Washington University School of MedicineUniversity, hospital or other
Collaborators: National Institute of Environmental Health Sciences (NIEHS)
Study start: 12 Jun 2025 (actual)
Primary completion: 18 Jul 2025 (actual)
Study completion: 18 Jul 2025 (actual)
First posted: 13 Jun 2025 (actual)
Results: Posted 14 Oct 2026

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Other
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2

Arm	Type	Receives
Epigenetics Video	Experimental	Behavioral: Epigenetics VideoParticipants will watch a brief (<5 minute) video about the concept of Epigenetics
Nanotechnology Video	Active comparator	Behavioral: Nanotechnology VideoParticipants will watch a brief (<5 minute) video about nanotechnology

Who may qualify

Ages: 18 years and older
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (7 listed)

English language speaker,
Non-Hispanic White
Non-Hispanic Black,
Non-Hispanic Asian
Non-Hispanic Indigenous (i.e., Alaska Native/Native Hawaiians/American Indian/Other Pacific Islander)

Key exclusion criteria (1 listed)

Self-identify as a genetics expert

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Epigenetics VideoEducational video about health and epigenetics.	Behavioural	Epigenetics Video
Nanotechnology VideoEducational video about nanotechnology	Behavioural	Nanotechnology Video

Primary outcome

Knowledge & Understanding of Epigenetics Information
Time frame: After intervention video
We will measure this outcome using a sum score of correct answers for 8 individual items. Scale ranges from 0 points to 8 points with higher scores indicating higher epigenetics knowledge.

2 secondary outcomes

Acceptability of Epigenetics Information
Time frame: After intervention video
Perceptions of Epigenetic Information
Time frame: After intervention video

Results and safety

Results posted to the registry on 14 Oct 2026, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Epigenetics Video	1,637	1,637
Nanotechnology Video	403	403

Primary outcome: Knowledge & Understanding of Epigenetics Information

Time frame: After intervention video. Mean (95% Confidence Interval). Unit: Sum Score of Knowledge Items

Measure	Epigenetics Video n = 1310	Nanotechnology Video n = 313
Value	5.44 (0.13)	4.09 (0.28)

Epigenetics Video vs Nanotechnology Video: Mean Difference (Final Values): 1.35 (95% CI 1.06 to 1.65), p <0.001, t-test, 2 sided

Population analysed: We excluded participants who met the following criteria: inattentive responders (defined as answering incorrectly to an attention check question \[to show you read carefully, leave this question blank\] OR participants who self-reported paying no or a little bit of attention to the survey questions), completing the survey in less than half of the median response time, and not watching the full experimental or control condition video. This resulted in n=1623 participants in the analytical sample.

2 secondary outcomes are reported in the full results.

Adverse events

Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Epigenetics Video	0 of 0	0 of 0	0
Nanotechnology Video	0 of 0	0 of 0	0

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Individual participant dataSharing planned: Yes

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Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
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A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
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Recruiting
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Epigenetics Video and Nanotechnology Video in people with Healthy, run by Washington University School of Medicine at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 14 Oct 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Knowledge & Understanding of Epigenetics Information (time frame: After intervention video). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07020234.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.